Table of Content

Open Access Editorial

Acknowledgment to Reviewers of OBM Neurobiology in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/obm.neurobiol.2301149

Abstract

The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication, and they can download a certificate of reco [...]

798 4861

Open Access Review

Leveraging DNA Databases to Reconnect Families Separated by Conflicts and Humanitarian Crises

Received: 14 May 2025;  Published: 15 July 2025;  doi: 10.21926/obm.genet.2503304

Abstract

Ongoing global conflicts and humanitarian crises have led to unprecedented displacement, including millions of separated children, many of whom, especially infants, cannot be traced using traditional methods. This paper advocates for the establishment of a voluntary, privacy-protected global DNA database, managed by an extra-governmental entity, to facilitate family reunification. It presents a comprehensive socio-technical framework that synthesizes a novel operational model with the requisite legal and ethical sa [...]

959 4860

Open Access Editorial

Driving Safety in Healthy Aging and Age-Related Diseases

Received: 03 April 2023;  Published: 04 April 2023;  doi: 10.21926/obm.geriatr.2302232

Abstract

EditorialDriving Safety in Healthy Aging and Age-Related DiseasesMichael Falkenstein *, Ute Brüne-CohrsALA Institute, 44805 Bochum, Germany; E-Mails: falkenstein@ala-institut.de; Ute.Bruene-Cohrs@ruhr-uni-bochum.de * Correspondence: Michael Falkenstein; E-Mail: falkenstein@ala-institut.deSpecial Issue: Driving Safety in Healthy Aging and Age-Related DiseasesOBM Geriatrics 2023, volume 7, issue 2 doi:10.21926/obm.geriatr.2302232Received: April 03, 2023Accepted: April 03, 2023Published: April 04, 2023

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Open Access Case Report

Becker Phenotype Muscular Dystrophy in a Man with Klinefelter Syndrome: A Rare Association

Received: 08 July 2024;  Published: 26 September 2024;  doi: 10.21926/obm.genet.2403262

Abstract

To present a rare clinical case of a man affected simultaneously by Becker phenotype Muscular Dystrophy (MD) and Klinefelter syndrome and the way how he was diagnosed. A 35-year-old man was evaluated in the context of hospitalization for respiratory failure. Since childhood, he had a clinical and muscle biopsy diagnosis of muscular dystrophy, possibly type Becker. His physical examination showed severe weakness of the pelvic and shoulder girdle, with a waddling gait, grade II scoliosis associated with tall height, [...]

785 4844

Open Access Concept Paper

FlowingLife: AI Enhancing Environmental and Economic Benefits for Aquatic Ecosystems Based on Optimizing Altered Flow Regimes

Received: 01 August 2024;  Published: 24 December 2024;  doi: 10.21926/aeer.2404028

Abstract

This proposed FlowingLife framework addresses the challenges of optimizing altered flow regimes in Irish plans and programs to improve Irish aquatic ecosystems' economic and environmental outcomes. The framework uses Artificial Intelligence (AI) techniques to revolutionize flow regime management and decision-making processing, providing sustainable resource allocation, climate change adaptation, and aquatic habitat conservation. The potential of identifying optimization guides thoroughly evaluating Irish Plans, inc [...]

937 4832

Open Access Original Research

Physico-Chemical Study of the Anti-Diabetic Drug of [BzN-EJJ-amide] for Treatment Type2 Diabetes Using CNT Sensor by Drug Delivery Method

Received: 22 February 2024;  Published: 19 June 2024;  doi: 10.21926/obm.genet.2402245

Abstract

The potential and selective inhibitors of protein tyrosine phosphatase 1B (PTP1B) are therapeutically useful in treating type 2 diabetes. N-Benzoyl-L-glutamyl-[4-phosphono(difluoromethyl)]-L-phenylalanine-[4-phosphono(difluoro-methyl)]-L-phenylalanineamide (BzN-EJJ-amide) (BGD) which is the ligand of 1LQF protein code extracted from protein data bank (PDB) is an inhibitor of PTP-1B that indicates selectivity over several protein tyrosine phosphatases. In this research, the interaction between the anti-diabetic drug [...]

1032 4814

Open Access Review

Exploring Multitargets Treatment for Diabetes

Received: 17 February 2024;  Published: 30 July 2024;  doi: 10.21926/obm.genet.2403254

Abstract

Diabetes Mellitus (DM) is a degenerative disease that modifies the body’s glucose metabolism. Although glucose is a vital energy source for body cells, individuals with diabetes can either not use insulin efficiently or do not create enough of this hormone, which controls blood sugar. This review aimed to explore the multi-target treatment for diabetes. This study investigates explicitly recent reports published in peer-reviewed journals indexed in various databases, including Web of Science, Scopus, PubMed, Google [...]

686 4813

Open Access Original Research

Quantitative Evaluations on Harmonic and Anharmonic Lattice Thermal Capacity of Polymers

Received: 28 December 2024;  Published: 22 May 2025;  doi: 10.21926/rpm.2502008

Abstract

So-called ‘Generalized Skettrup Model(s)’ (GSMs) of different (1D, 2D, 3D) spatial dimensionalities are used at simulations on temperature-dependent harmonic and anharmonic fractions of lattice thermal capacity of polyethylene and polypropylene with crystalline and/or amorphous atomic structures of limited spatial extents. Basic equations of the GSM slot in explicitly quantization effects of the single-particle and many-particle energy levels of spatially confined phonons. The harmonic lattice thermal c [...]

843 4805

Open Access Editorial

Opportunities and Challenges of Molecular Catalysts

Received: 28 November 2024;  Published: 02 December 2024;  doi: 10.21926/cr.2404013

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Open Access Research Article

Evaluating Screening Guidelines for Disruptive Behavior Problems in Children: A Systematic Review of the Accuracy of Parents’ Concerns

Received: 31 May 2024;  Published: 08 February 2025;  doi: 10.21926/obm.icm.2501009

Abstract

Disruptive behavior problems (DBPs) in young children are early indicators of potential disruptive behavior disorders (DBD), which can lead to negative health and social outcomes. Secondary prevention strategies that target DBPs may facilitate early interventions and reduce these risks. Current Canadian pediatric practice guidelines provide an example one such strategy and suggest screening for DBPs only if a child’s parent reports concerns about their behavior. This systematic review sought to determine if parents [...]

912 4799

Open Access Correction

Correction: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183

Received: 11 March 2024;  Published: 12 March 2024;  doi: 10.21926/obm.neurobiol.2401213

Abstract

CorrectionCorrection: Tse et al. How COVID-19 Ceases All Older Adult Services & the Way Out for Community-Dwelling Older Adults with Chronic Pain. OBM Neurobiology 2023; 7: 183Mimi Mun Yee Tse 1, *, Shamay Sheung Mei Ng 2, Vivian Lou 3, Raymond SK Lo 4, Daphne Sze Ki Cheung 5, Paul H Lee 6, Shuk Kwan Tang 7, Siu Hang Leung 1, Percy Poo-See Tse 1* Correspondence: Mimi Mun Yee Tse; E-Mail: mmytse@hkmu.edu.hkAcademic Editors: Ines Testoni, Adriano Zamperini and Lorenza PalazzoSpecial Issue: How COVID-19 Changed Indi [...]

1012 4798

Open Access Original Research

Chest CT Scan Features of COVID-19 in a Hospitalized High-Altitude Population

Received: 30 November 2022;  Published: 12 April 2024;  doi: 10.21926/obm.genet.2402226

Abstract

There is a lack of knowledge regarding the type of lung compromise in high-altitude residents with COVID-19. This study aims to evaluate the lung compromise in chest CT scans of high-altitude dwellers hospitalized with COVID-19. Retrospective study that took place in "Daniel Alcides Carrión" Regional Hospital, located 3,250 meters above sea level in the city of Huancayo, Perú. 464 medical charts and chest CT images of hospitalized patients with confirmed COVID-19 from January to March 2021 were reviewed. The mean a [...]

959 4794

Open Access Review

Platelet Immune Interactions, Lifespan, and Senescence

Received: 18 July 2024;  Published: 23 January 2025;  doi: 10.21926/obm.geriatr.2501297

Abstract

In addition to their hemostatic functions, platelets play an essential role in immunologic interactions, which is confirmed by the observation of an increase in platelet counts in patients with immune-related thrombocytopenia and other autoimmune diseases after immunomodulatory treatment with intravenous human immunoglobulin concentrate. The mechanisms of action of this biological therapeutic option induce the development of therapeutic monoclonal antibodies, agonists, and antagonists that target the complex pathop [...]

890 4790

Open Access Original Research

Comparison of Muscle Damage Markers and Myokines between Adult and Middle-Aged Marathon Runners

Received: 20 August 2024;  Published: 28 February 2025;  doi: 10.21926/obm.geriatr.2501301

Abstract

This study compared markers of muscle damage and myokines between adult and middle-aged runners before and after the marathon. Seventy-four male runners: 48 adults aged 30-44 years (AA group), and 26 middle-aged individuals aged 45-59 years (MA group) participated of the study. Blood samples were collected 24 hours before, immediately after, 24 hours and 72 hours after the marathon to measure skeletal and cardiac muscle damage markers (CK, LDH, troponin, and proBNP) and myokines (IL-6, IL-15, decorin, BDNF, GDF-15, [...]

881 4788

Open Access Original Research

Photon Recycling for Indoor Energy Harvesting: Optical Optimization of LED-Driven Silicon Photovoltaic Systems

Received: 06 July 2025;  Published: 11 September 2025;  doi: 10.21926/jept.2503013

Abstract

Indoor environments offer a unique opportunity for photon recycling using LED-based illumination, particularly to address energy limitations of solar photovoltaic (PV) systems during nighttime or in low-light conditions. This study presents an optical and electrical performance evaluation of silicon-based photovoltaic (SPV) panels operating under controlled indoor LED lighting. Despite the low irradiance (~1.4 mW/cm2), significant power output was achieved through engineered panel configurations and optimized light [...]

1029 4788

Open Access Original Research

Opioid-Involved Elder Abuse in the United States: Perspectives from Adult Protective Services

Received: 23 August 2024;  Published: 09 January 2025;  doi: 10.21926/obm.geriatr.2501294

Abstract

The purpose of this descriptive study was to understand the nature, extent, and challenges confronted by APS programs in the United States in providing services to older clients affected by opioids. The study design involved a two-step process: Phase I involved telephone interviews with state-level Adult Protective Services administrators from 11 states considered to be “hot-bed states” for the opioid epidemic. Findings from the administrator interviews informed questions for Phase II telephone interviews with indi [...]

975 4778

Open Access Original Research

Computer-Aided Study on Metal Complexes with Benzohydrazide Schiff Base as Potential Bacterial and Fungi Inhibitors

Received: 22 October 2024;  Published: 06 March 2025;  doi: 10.21926/rpse.2501002

Abstract

The biochemical properties of metal complexes containing benzo hydrazide Schiff base have been reported by numerous researchers worldwide in various ways. In this work, the evaluation of biochemical roles of the metal complexes with benzo hydrazide Schiff base activity as anti-gram positive and gram-negative bacteria, as well as antifungal agents, were observed. The use of various techniques, including the induced fit docking methodology, the density functional theory method, and pharmacokinetics investigations wit [...]

1175 4776

Open Access Editorial

Acknowledgement to Reviewers of OBM Geriatrics in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/obm.geriatr.2301221

Abstract

The editors of OBM Geriatrics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition dire [...]

794 4775

Open Access Short Report

Integrating Palliative Medicine into Medical Education: Creating a More Compassionate Generation of Physicians

Received: 26 February 2024;  Published: 01 July 2024;  doi: 10.21926/obm.geriatr.2403281

Abstract

How should Palliative Medicine competencies be taught to medical students? In the United States and other countries, there is a consensus that teaching Palliative Medicine competencies to medical students is essential. Health agencies have also identified teaching Palliative Medicine competencies as crucial. According to Sanchez-Reilly and Ross, medical students reported that they feel better prepared to care for the elderly, patients with severe illness, and dying patients after completing formal training. The aut [...]

837 4759

Open Access Research Article

Analysis of Global Scientific Production on Health Service Waste through Bibliometric and Scientometric Indicators

Received: 19 October 2024;  Published: 27 April 2025;  doi: 10.21926/aeer.2502021

Abstract

Inadequate management of healthcare waste represents a significant challenge to public health and the environment. This study aims to analyze global scientific production on healthcare waste using bibliometric and scientometric indicators, providing a comprehensive overview of research trends and areas of interest. Data from academic databases were used to map the temporal distribution of publications, identify the leading countries, institutions, and researchers involved, and evaluate collaboration networks and jo [...]

1074 4754

Open Access Original Research

Effect of Drought Stress on Agronomic Traits and Total Leaf Proteins in Different Bottle Gourd [Lagenaria siceraria (Molina) Standl.] Genotypes

Received: 16 July 2024;  Published: 16 October 2024;  doi: 10.21926/obm.genet.2404267

Abstract

Breeding drought-tolerant genotypes using genetic and biochemical tools is an important mitigation strategy to improve stress response and yields in bottle gourd [Lagenaria siceraria (Molina) Standl.]. This current study evaluated the variations among bottle gourd genotypes for potential breeding purposes by establishing the relationship between agronomic traits and the protein profile required for the plants’ resilience against drought stress. The study assessed 12 bottle gourd accessions grown under non-str [...]

1078 4752

Open Access Original Research

Identification of Soybean Components that Prevent the Entry of Influenza Virus

Received: 31 August 2024;  Published: 01 April 2025;  doi: 10.21926/rpn.2502005

Abstract

We have previously demonstrated the anti-influenza virus activity of a soybean extract, indicating the presence of compounds that prevent viral entry into cells. In this study, we sought to identify the compounds in hydrothermal extracts of soybean that blocked viral entrance and analyzed their mechanisms of action. Hot aqueous extracts of roasted soybeans were separated by reverse-phase chromatography on an octadecylsilyl C18 column, and the antiviral activity of individual fractions was measured during the viral [...]

954 4749

Open Access Editorial

Acknowledgment to Reviewers of Journal of Energy and Power Technology in 2023

Received: 04 January 2024;  Published: 05 January 2024;  doi: 10.21926/jept.2401001

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can [...]

951 4742

Open Access Review

Clinical Trials Characterizing the Serum 25-Hydroxyvitamin D Response to Vitamin D Supplementation in Children: A Systematic Review and Meta-Analysis

Received: 13 September 2024;  Published: 29 October 2025;  doi: 10.21926/rpn.2504024

Abstract

Recommendations for vitamin D supplementation are essential for the prevention and therapy of vitamin D deficiency. However, reliable data remain lacking for children, as most intake recommendations are based on individual studies. This work aimed to obtain reliable data that allow health authorities to re-evaluate recommendations for oral vitamin D uptake in children. We conducted a systematic literature search in MEDLINE/PubMed on vitamin D supplementation in children. All randomized controlled trials (RCTs) publ [...]

1020 4736

Open Access Original Research

Experiences and Support Needs of Informal Caregivers in Managing Behavioral Symptom of Dementia

Received: 03 October 2024;  Published: 10 April 2025;  doi: 10.21926/obm.geriatr.2502306

Abstract

About 90% of people living with Alzheimer's disease and related dementias experience behavioral and psychological symptoms during the course of the disorder. Although extensive research exists on the roles of informal caregivers in dementia care, their abilities to manage behavioral symptoms and the resources they turn to for support remain understudied. This phenomenological study explored informal caregivers' experience, knowledge sources, and self-initiated strategies for managing behavioral symptoms of dementia [...]

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