Table of Content

Open Access Concept Paper

Four Decades of Newborn Screening: A Historical Perspective of Laboratory Practices

Received: 21 March 2023;  Published: 30 October 2023;  doi: 10.21926/obm.genet.2304201

Abstract

The personal experience of 36 years in charge of the Newborn Screening Laboratory in Galicia and the consequences of the recent advancement of sampling from 3 days to 24 hours of the newborn's life are reviewed. The implication in the results of the assay of reducers in urine with the Mandelin reagent and its alternatives is commented. The implication in the effects of TSH in blood and the possible ways of dealing with the situation. Since 1978, the Newborn Screening Program in Galicia has maintained the urine samp [...]

1072 5700

Open Access Original Research

Where Older Patients with Cancer Die? A Retrospective Study

Received: 10 July 2023;  Published: 16 November 2023;  doi: 10.21926/obm.geriatr.2304258

Abstract

Home is the preferred place of death for most cancer patients. We examined which characteristics of older patients with cancer may have influenced this choice and how important may be relevant an early collaboration between oncologists and palliatives. Hospitalized patients aged ≥70 were screened by G8 questionnaire and evaluated by Comprehensive Geriatric Assessment (CGA) to identify frail and unfit ones and define the most appropriate end-of-life setting with palliatives. Using the G8 questionnaire, we screened 1 [...]

1385 5679

Open Access Editorial

Acknowlegement to Reviewers of Journal of Energy and Power Technology in 2020

Received: 07 January 2021;  Published: 07 January 2021;  doi: 10.21926/jept.2101002

Abstract

The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...]

1200 5670

Open Access Interview

An Interview with Dr. Sok Cheon Pak

Received: 18 September 2022;  Published: 20 September 2022;  doi: 10.21926/obm.icm.2203043

Abstract

Interview with Dr. Sok Cheon Pak. Dr Pak as a physiologist currently leads and guides research into nutraceuticals to provide relevant and impactful clinical applications. The best example is the rice bran arabinoxylan compound (RBAC). RBAC is a functional food produced from hydrolysed rice bran denatured with shiitake mushroom enzymes. RBAC demonstrates strong immunomodulatory properties, particularly for enhancing the natural killer cell activity. Additionally, RBAC is a potent antiproliferative food supplement w [...]

937 5669

Open Access Original Research

An Application of Excess Solar and Storage Capacity Optimization for Grid Services

Received: 11 May 2024;  Published: 20 September 2024;  doi: 10.21926/jept.2403017

Abstract

This initiative aims to enhance the efficiency of utility demand response (DR) operations by coordinating and integrating behind-the-meter (BTM) photovoltaic systems (PV) and energy storage (ES) using innovative machine learning software applications embedded in a distributed control architecture. The project is in the process of creating distributed energy resource (DER) learning agents and optimization engine within a hierarchical and layered distributed control architecture (DCA). These components work together [...]

1058 5666

Open Access Original Research

Attitudes and Motivations Towards Implantation of Intention Towards Exercise among Entrepreneurs: A Brain Freshness Activity

Received: 19 October 2023;  Published: 10 April 2024;  doi: 10.21926/obm.neurobiol.2402216

Abstract

In the contemporary landscape, developing individuals' attitudes, motivations, and intentions toward exercise and physical activities emerges as an imperative cornerstone for fostering a healthy and thriving lifestyle. The present study examines the effect of the theory of the planned behavior (TPB) constructs on exercise motivation (MT) and intention towards exercise (ITWE) among Egyptian entrepreneurs. The study employed a quantitative approach and collected cross-sectional responses from entrepreneurs throug [...]

1114 5635

Open Access Original Research

Potential CRISPR-Cas9-based Antiviral Activity Against Hepatitis C Virus in Liver Cancer

Received: 04 July 2024;  Published: 28 February 2025;  doi: 10.21926/obm.genet.2501287

Abstract

Hepatitis C virus (HCV) is a primary global health concern, and though therapeutic options have improved, no very effective vaccine is available despite decades of research. The health and vitality of the organism are related to the result of homeostatic regulation of the internal environment. In contrast, it follows that disruption of homeostatic mechanisms leads to disease, particularly in liver cancer. Since HCV can rapidly mutate to evade the immune response, an effective HCV vaccine must rely on the identifica [...]

1239 5631

Open Access Original Research

Elaboration, Structural and Optical Characterization of the New Ternary Chalcogenide SnSb2S5

Received: 29 March 2024;  Published: 17 July 2024;  doi: 10.21926/jept.2403013

Abstract

In this study, tin antimony sulfide (SnSb2S5) thin films with 200 nm, 312 nm, and 431 nm thicknesses were successfully fabricated using thermal evaporation. These films' structural, optical, and photoanode properties were meticulously characterized to assess their suitability for photovoltaic applications. X-ray diffraction (XRD) analysis confirmed the presence of an orthorhombic symmetry phase within the Pnma space group, ensuring the crystalline quality of the films. Raman spectroscopy further validated the cryst [...]

981 5630

Open Access Research Article

Possibilities of Predicting a Person's Substance Use Behaviour and Mental Health Through Social Media in a COVID-19 Crisis Context

Received: 18 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.icm.2304049

Abstract

The negative psychological consequences of the COVID-19 pandemic and the forced isolation of a large proportion of people worldwide have demonstrated the need to develop ways and technologies to reduce the effects of sudden threats of this type. The basis of any practical work to minimize the negative psychological consequences of the COVID-19 pandemic associated with substance use is the monitoring and diagnosis of the psychological resources of the individual. The article aims to show the possibilities of predict [...]

1078 5612

Open Access Research Article

A Tail Within a Tale, Within a Tale: An Autoethnographic Account for Dog Lovers, Cat Lovers, and Story Lovers

Received: 16 October 2023;  Published: 21 December 2023;  doi: 10.21926/obm.icm.2304062

Abstract

It was March-April 2020. The first few weeks of the first COVID-19 pandemic lockdown had just begun. Anxiety levels were high, and being locked up at home was an unfamiliar and eerie situation. A music therapist sent her clients (elementary school children on the autism spectrum) daily videos of her dog, Robben, during his daily routines. She dubbed the dog as if he told the children a story about a tail-less cat. This endeavor resulted in a series of 27 storytelling episodes titled “Robben’s Pandemic Adventures”, [...]

1089 5609

Open Access Original Research

The Timing of Endoscopic Evaluation of Anti-TNFα Therapy Patients with Ulcerative Colitis

Received: 10 August 2020;  Published: 09 July 2021;  doi: 10.21926/obm.hg.2103058

Abstract

Anti-TNFα Therapy are used to induce remission and as maintenance therapy in refractory ulcerative colitis (UC) to achieve mucosal healing (MH). However, the time at which mucosal healing should be assessed is unclear. We retrospectively examined the optimal timing for colonoscopy and the criteria to determine the need for the continuation of treatment. We evaluated 44 UC patients that were treated with anti-TNFα Therapy and categorized them into the following groups according to the degree of MH within 12 months: [...]

1057 5607

Open Access Original Research

Exploring the Opportunities and Barriers of Implementing the Health Focused Physical Therapy Model

Received: 21 June 2024;  Published: 19 September 2024;  doi: 10.21926/obm.icm.2403052

Abstract

The Health-Focused Physical Therapy Model integrates lifestyle behavior management into physical therapy practice using a standardized care model and motivational patient interviewing. The purpose of this study was to identify the perceived opportunities and barriers physical therapists, physical therapist assistants, and rehab administrators may face when implementing the model. This study included a survey of 19 physical therapy clinicians, and interviews with four rehabilitation administrators from one healthcar [...]

965 5604

Open Access Review

The Cellular Mechanism of Aging as Programmed Epigenetic Phenomenon: From Hypothesis to Scientific Evidence

Received: 04 December 2024;  Published: 10 September 2025;  doi: 10.21926/obm.geriatr.2503325

Abstract

There is a main difference between theories explaining aging as an adaptive phenomenon that is determined and modulated by genes (i.e., the result of a specific “program”) and theories explaining aging as a non-adaptive phenomenon caused by the accumulation of random degenerative events. In fact, for adaptive theories, a genetically determined and modulated program determining aging is indispensable, while for non-adaptive theories, such a program cannot exist. However, there appears to be strong evidence to suppor [...]

1375 5599

Open Access Editorial

Acknowledgement to Reviewers of Catalysis Research in 2022

Received: 04 January 2023;  Published: 04 January 2023;  doi: 10.21926/cr.2301003

Abstract

The editors of Catalysis Research would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recogn [...]

910 5592

Open Access Original Research

Artocarpus Communis Seed Regulates P53, IRS, HsD17β2, FTO, and CYP11a Genes in Polycystic Ovarian Syndrome Rats

Received: 20 November 2023;  Published: 20 February 2024;  doi: 10.21926/obm.genet.2401213

Abstract

Polycystic ovarian syndrome (PCOS) is a prevalent endocrine illness that affects 5-10% of reproductive women globally. It is a multifaceted hormonal disorder characterized by the involvement of numerous molecular mechanisms that contribute to its development. This study investigates the effect of Artocarpus communis seed on the hormonal imbalance and P53, IRS, HsD17β2, FTO, and CYP11a genes expression in the ovaries of letrozole-induced polycystic ovarian syndrome rats. To induce PCOS in 30 female Wistar rats, [...]

1332 5579

Open Access Interview

An Interview with Dr. Carlo Pedrolli

Received: 01 June 2022;  Published: 09 June 2022;  doi: 10.21926/obm.geriatr.2202199

Abstract

InterviewAn Interview with Dr. Carlo PedrolliOBM Geriatrics Editorial OfficeLIDSEN Publishing Inc., 2000 Auburn Drive, One Chagrin Highlands, Suite 200, Beachwood, OH, USA; E-Mail: geriatrics@lidsen.comOBM Geriatrics 2022, volume 6, issue 2 doi:10.21926/obm.geriatr.2202199Received: June 01, 2022Accepted: June 02, 2022Published: June 09, 2022

810 5572

Open Access Original Research

Experimental Study and Kinetic Modeling of Agro-Industrial Wastes for Conversion to Fuel Gas via the Boudouard Reaction

Received: 12 November 2024;  Published: 24 January 2025;  doi: 10.21926/jept.2501004

Abstract

Independent parallel reactions (IPR) and distributed activation energy (DAEM) kinetic models were developed and compared for the combined pyrolysis-gasification of two agro-industrial waste materials. The aim was to recycle greenhouse gas carbon dioxide for mitigating emissions, to evaluate the thermal behavior, reactivity, conversion and product composition in terms of structural/chemical characteristics of the fuels, and to provide accurate kinetic parameters useful in the scaling-up of the process. The experimen [...]

1290 5566

Open Access Original Research

A Technology-Aided Program to Help People with Profound Intellectual and Multiple Disabilities Access Preferred Stimulation and Exercise Motor Responses and Visual Orientation

Received: 14 March 2024;  Published: 28 June 2024;  doi: 10.21926/obm.neurobiol.2402228

Abstract

People with profound intellectual and multiple disabilities (PIMD) are generally isolated, with a high risk of reduced stimulation input and physical inactivity. One of the strategies available to mitigate this situation relies on using technology-aided programs delivering stimulation contingent on people’s basic responses/activation. The two studies reported here were intended to extend the evidence available in this area. Specifically, Study I assessed whether a technology-aided program, which enabled participant [...]

1049 5562

Open Access Review

Review of Heterotopic Heart Transplantation Models in Rats

Received: 21 October 2024;  Published: 14 March 2025;  doi: 10.21926/obm.transplant.2501242

Abstract

Heterotopic heart transplantation (HHT) in rats is a valuable tool for cardiac transplantation research. While abdominal HHT has been established in rats for nearly 90 years, novel approaches involving cervical and femoral techniques have also been explored. The abdominal HHT model, despite its long history, is technically demanding and has a steep learning curve. In contrast, the cervical HHT model enables surgeons with more basic microsurgical skills to achieve competency more quickly while producing comparable o [...]

1216 5556

Open Access Interview

An Interview with Dr. Francisco J. Barrantes

Received: 22 September 2022;  Published: 26 September 2022;  doi: 10.21926/obm.neurobiol.2203136

1033 5553

Open Access Original Research

Elementary Collective Effects in Systems Containing Small Fermion-Numbers

Received: 14 October 2023;  Published: 06 February 2024;  doi: 10.21926/rpm.2401004

Abstract

Collective effects are a typical nuclear feature that refers to the behavior of a group of N fermions (protons and neutrons) within the atomic nucleus. Our interest lies in light nuclei only. Thus, we consider here, using the Lipkin model, a small-N fermion system at low-temperature T and discover -collective phenomena. Our fermion-model simplicity allows one to gain insight into collective fermion behavior. We focus attention, for N<20, on several quantifiers. These include standard ones related to thermal [...]

1310 5543

Open Access Original Research

Trace Elements Spatial Distribution in the Groundwater near the Subarnarekha River Basin - Jamshedpur, India

Received: 07 August 2024;  Published: 06 December 2024;  doi: 10.21926/aeer.2404027

Abstract

The present study assessed the spatial distribution of trace elements in the groundwater near the Subarnarekha River Basin - Jamshedpur, India. Half of this city's water need (48.11%) relies on groundwater resources. GIS-based maps were constructed using ArcGIS 10.3 software to describe the spatial distribution of Arsenic (As), Barium (Ba), Cadmium (Cd), Chromium (Cr), Cobalt (Co), Copper (Cu), Iron (Fe), Manganese (Mn), Molybdenum (Mo), Nickel (Ni), Selenium (Se), and Strontium (Sr). The concentration of trace ele [...]

1021 5539

Open Access Editorial

Acknowledgment to Reviewers of OBM Genetics in 2022

Received: 05 January 2023;  Published: 05 January 2023;  doi: 10.21926/obm.genet.2301175

Abstract

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2022. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition direct [...]

874 5538

Open Access Original Research

Low Mortality Associated with COVID-19 Infection in Lung Transplant Recipients at a Single Center

Received: 15 October 2023;  Published: 28 April 2024;  doi: 10.21926/obm.transplant.2402213

Abstract

Lung Transplant Recipients (LTR) are particularly vulnerable to severe infection, hospitalization, and death due to community acquired respiratory viruses. As a result, the global SARS-Cov-2 pandemic poses a higher risk to this population. We aim to study the lung function, severity of infection and mortality among LTR at a single center. A retrospective chart review was performed on all LTR at the University of San Diego, California Medical Center between June 2020 and September 2022. Spirometry was performed at 1 [...]

948 5533

Open Access Original Research

The Multigenerational Legacy of Diabetes and Illness Perception: Influence on Older Adult’s Stigma

Received: 03 February 2024;  Published: 29 May 2024;  doi: 10.21926/obm.geriatr.2402280

Abstract

There is not enough information regarding the impact of stigma associated with a. diagnosis of diabetes in aging older adults. Perceptions of diabetes are passed down generationally and may be influenced by mainstream societal perceptions at the time the perception is shaped. This is known as a multigenerational legacy of diabetes for those with whom the perceptions are shaped within families when a hereditarily predisposed condition occurs. In this study, participants over the age of (n = 88) 60 years old were adm [...]

1143 5528

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