by Azza. A. Abou-Hussein  , Wolfgang Linert  and Nelly H. Mahmoud

Received: 18 September 2019;  Published: 19 November 2019;  doi: 10.21926/acr.1904001

Mixed ligand copper(II) complexes of the empirical formula [Cu (L)(TFAA)]X, where L represents 2,2´-bipyridine (Bipy), 1,10´-phenanthroline (Phen), or 4,7-diphenyl-1,10´- phenanthroline (Dphen), TFAA is 1,1,1-Trifluoro-2,4-pentanedione, and X is the counter ion (BF4- or ClO4-), were synthesized and characterized by spectroscopic, magnetic, molar conductance, elemental, and thermal analysis. Solvatochromic studies revealed that all the complexes showed bathochromic shifts. A square planar geometric structure is prop [...]

by Cosimo Magazzino  and Marco Mele

Received: 19 February 2021;  Published: 06 May 2021;  doi: 10.21926/aeer.2102008

In this study, we used an image neural network model to assess the relationship between economic growth, pollution (PM2.5, PM10, and CO2), and deaths from COVID-19 in the Hubei area (China). Data analysis, neural network analysis, and deep learning experiments were carried out to assess the relationship among COVID-19 deaths, air pollution, and economic growth in China (Hubei province, the epicenter of the COVID-19 pandemic). We collected daily data at a city level from January 20 to July 31, 2020. We used main cit [...]

by A. Guillermo Bracamonte

Received: 24 November 2024;  Published: 18 February 2025;  doi: 10.21926/rpm.2501007

The generation of non-classical light with improved performances within tiny sizes, intervals of lengths, and diameters is still a challenge. The generation of variable wavelengths associated with different frequencies of energy modes produced from new sources of emitters within confined scales from the Quantum to Nano-and Micro-scales are of high impact. It is noted here that the concept of the generation of non-classical light related to electronics and photonics interactions with different topological matter con [...]

by Kiril Fedorov  , Sonia Sheikh  , Alex Romaschin  and Michael Thompson

Received: 03 May 2020;  Published: 18 August 2020;  doi: 10.21926/rpm.2003019

During a variety of medical procedures such as renal dialysis, bypass surgery, and lung transplantation patient blood is exposed to the surface of a number of polymeric materials such as polycarbonate (PC), poly (vinyl chloride) (PVC) and polysulfone (PS) for a period up to several days. Such exposure may result in undesirable protein-material interactions that can potentially trigger deleterious biological processes including thrombosis, which may be responsible for other complications such as cognitive disability [...]

by Jamie A. Chin  and Wilson C. Chin

Received: 12 February 2022;  Published: 23 May 2022;  doi: 10.21926/jept.2202018

Flows in multi-branch piping systems are modeled for linear Newtonian and nonlinear Power Law, Bingham Plastic and Herschel-Bulkley fluids. The nonlinear models are often used to describe multiphase fluids consisting of liquid and solid phases, including cement slurries and drilling muds in petroleum engineering. Rheological and heterogeneous multiphase effects are important to blood flows in single and bifurcated arteries, capillaries and veins – biological applications are also emphasized to highlight their incre [...]

by Giuseppe Cocco  and Philipp Amiet

Received: 23 March 2021;  Published: 30 July 2021;  doi: 10.21926/obm.genet.2103133

“Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work. Unlike genetic changes, epigenetic changes are reversible and do not change your DNA sequence, but they can change how your body reads a DNA sequence” (https://www.cdc.gov/genomics/disease/epigenetics.htm). Epigenetic interactions, along with the genetic expression in innate cells, change the structure and function of chromatin, and thus, turn the genes on and off. Epigenetic changes influence dise [...]

by Oya M. Andacoglu  , Jack Liu  , Abigail L. Brooks  , Amit Blumfield  , Mehul Trivedi  , Shoshana Lehman  , Michael K. Parides  , Enver Akalin  , Jay A. Graham  , Juan P. Rocca  and Stuart M. Greenstein

Received: 17 March 2021;  Published: 20 July 2021;  doi: 10.21926/obm.transplant.2103150

Glomerular filtration rate (GFR) is an excellent indicator of renal function; however, it is rarely evaluated as an endpoint. We investigated donor and recipient factors for associations that might be predictive of mid-term GFR after renal transplantation. We performed a retrospective review of 828 deceased donor renal transplantations performed at Montefiore Medical Center between the years 2009-2015. Donor characteristics included KDPI, [low (<20%), medium (20-80%), high (>80%)], age, graft types [extended [...]

by Mouna Daldoul  , Rim Charfi  , Khouloud Ferchichi  , Mouna Ben Sassi  , Syrine Ben Hammamia  , Fatma Medhioub  , Emna Gaies  , Rym Enneifer  , Hanene Eljebari  , Anis Klouz  , Riadh Daghfous  and Sameh Trabelsi

Received: 20 August 2024;  Published: 13 December 2024;  doi: 10.21926/obm.transplant.2404228

A high intra and interindividual pharmacokinetics variability characterize Tacrolimus. Data regarding factors influencing its pharmacokinetics and pharmacodynamics in liver transplantation are limited. This study aimed to assess tacrolimus therapeutic response, pharmacokinetics and adherence in liver transplant recipients. The study was conducted at the Clinical Pharmacology Department for 12 years, from January 2009 to March 2021. We included liver transplant patients treated with tacrolimus referred to our depart [...]

by Eduardo Garrido  , Javier Botella de Maglia  , Oriol Sibila  and Gustavo Zubieta-Calleja

Received: 18 July 2022;  Published: 09 September 2022;  doi: 10.21926/obm.genet.2203163

High-altitude pulmonary edema (HAPE) and COVID-19 pneumonia are different diseases, but HAPE-susceptible individuals (whose susceptibility often has a genetic basis) can also suffer from severe COVID-19. We hypothesized that certain pathogenic mechanisms might overlap if such a coincidence occurs, since these patients could react to alveolar hypoxia with a more intense and heterogeneously distributed pulmonary vasoconstriction than non-HAPE-susceptible patients. It is also not known how future altitude acclimatizat [...]

by Krishanu Aich  , Sukrit Kashyap  , Konika Tyagi  , Ishika Verma  , Abhimanyu Chauhan  and Chakresh Kumar Jain

Received: 09 April 2022;  Published: 29 November 2023;  doi: 10.21926/obm.neurobiol.2304198

Today, the advancement of assessment, forecasting, and therapy or medical attention for psychological healthcare is already using artificial intelligence (AI) technology, particularly machine learning, due to the introduction of digital tools to treat mental health conditions. In mental health treatment, the present and the future of artificial intelligence technologies hold both enormous promises and potential dangers. With the current global scenario, psychological disorders like clinical depression, general anxi [...]

by Yuri Shavrukov

Received: 03 March 2020;  Published: 04 March 2020;  doi: 10.21926/obm.genet.2001104

by Filomena Papa  , Bartolomeo Sapio  and Enrico Nicolò

Received: 31 October 2018;  Published: 04 January 2019;  doi: 10.21926/obm.geriatr.1901028

Background: Information and Communication Technologies (ICTs) have the potential to promote healthy aging and increase the quality of life of older adults. However, several barriers like access, performance, psychological, and privacy issues still exist against fully deploying ICT solutions for older adults. To determine useful methods to overcome such barriers, this work investigated the possible factors that prevent elders from directly accepting ICT services based on three field studies. Methods: The Unified The [...]

by Paul D. Loprinzi  , Emily Frith  and Faith Harris

Received: 17 December 2018;  Published: 21 February 2019;  doi: 10.21926/obm.icm.1901011

Background: Learning and memory, unquestionably, are critical for many aspects of life, including acquisition and retention of educational material. The purpose of this brief narrative review is to provide a primer on empirical-based, learning and memory techniques. Methods: A narrative review approach is employed. Results: This review is structured by first discussing contextual factors that influence learning and memory, followed by addressing several specific techniques to help facilitate learning and memory ret [...]

by Kara B. Dassel  , Eli Iacob  , Rebecca L. Utz  , Katherine P. Supiano  and Hollie Furhmann

Received: 01 September 2022;  Published: 06 January 2023;  doi: 10.21926/obm.icm.2301004

Due to the insidious progression of Alzheimer's disease and related dementias (ADRD), surrogate decision-makers typically make medical and long-term-care decisions for a care recipient, most often a family care partner. Unfortunately, many care recipient/care partner dyads have failed to engage in advance care planning or have lost the opportunity to do so due to the cognitive decline of the care recipient. To address this need, our team created a validated dementia-focused advance care planning tool known as t [...]

by Stefan Hardy Lung  and Thomas Lung

Received: 30 November 2024;  Published: 14 April 2025;  doi: 10.21926/obm.geriatr.2502307

Cellular senescence (aging) is a physiological process that plays a role in tissue remodeling, wound healing, and embryogenesis. Prolonged senescence of cells can have detrimental effects and trigger a secretory phenotype (SASP, senescence-associated secretory phenotype), degenerative disorders, cancer, and age-related diseases. Suitable biomarkers and a range of different laboratory methods are used to investigate these complex relationships in vitro and in vivo. Since a universal biomarker for cell senescence has [...]

by Preeti Chhabra  and Kenneth L. Brayman

Received: 02 April 2018;  Published: 05 June 2018;  doi: 10.21926/obm.transplant.1802010

Pancreas or islet transplantation is the only reliable cure for Type 1 Diabetes. However, shortage of donor tissue supply, longitudinal graft attrition due to innate and adaptive immunity and the recurrence of autoimmunity, as well as the harmful side-effects of chronic immunosuppressive therapy limit the wide-spread acceptance of islet transplantation as a mainstream cure for autoimmune diabetes. Herein, preclinical and clinical stem-cells based research approaches aimed at obtaining large quantities of islets for [...]

by Deborah A. Sharpe  and Lisa D. Hinz

Received: 30 May 2023;  Published: 19 July 2023;  doi: 10.21926/obm.icm.2303029

This study explored how the global COVID-19 pandemic changed the ways in which art therapists use art in their therapeutic practice. Art has repeatedly been linked to healing in a variety of settings, but generally art therapists have been accustomed to conducting therapy sessions in person. Prior to the pandemic most art therapists preferred in-person sessions for a variety of therapeutic reasons. Although there are clearly downsides to meeting remotely, there have been unforeseen advantages, as well. The present [...]

by Clemens Drenowatz  , Gerson Ferrari  , Gerhard Ruedl  , Armando Cocca  and Klaus Greier

Received: 15 November 2021;  Published: 18 February 2022;  doi: 10.21926/rpn.2201004

Poor lifestyle choices in adolescents, including low physical activity (PA), excess screen time, and unhealthy dietary habits, are major threats to their health in the future. Unhealthy behaviors such as insufficient PA, high TV time, and poor dietary choices also tend to cluster, but information on the combined association of screen time, sports participation, and dietary habits is limited in Austrian youth. To examine the association among these behaviors, 165 adolescents (74 girls and 91 boys) between 11 and 14 [...]

by Oyovwi Mega Obukohwo  , Peggy Ejiro Ohwin  , Rotu Arientare Rume  , Olowe Gideon Temitope  , Oyelere Abosede Oreoluwa  and Adelowo Joy Motunrayo

Received: 19 February 2024;  Published: 05 July 2024;  doi: 10.21926/obm.genet.2403249

Chromosome abnormalities are a leading cause of pregnancy loss, developmental delays, and birth defects. These abnormalities arise from errors in chromosome structure (breakage) or number (missegregation) during cell division. Understanding the causes of these errors is crucial for developing effective preventive strategies to improve reproductive health. This paper aims to review the known causes of chromosome breakage and mis-segregation, emphasizing their impact on pregnancy and newborn health. It further explor [...]

by Hanneke van der Wal- Huisman  , Henk Groen  , Erik Heineman  and Barbara L. van Leeuwen

Received: 08 April 2020;  Published: 01 July 2020;  doi: 10.21926/obm.geriatr.2003125

Postoperative pain has a negative influence on physical and mental recovery and may result in a variety of postoperative complications. Listening to recorded music has been revealed to reduce pain, but in addition to that, live bedside music further offers the possibility to interact with the patient, respond to their emotions, and help them in adapting their conditions. It, therefore, seems appropriate for older surgical patients. This study examines the effect of live bedside music on postoperative elderly patien [...]

by Holly Hazlett-Stevens

Received: 12 April 2022;  Published: 07 June 2022;  doi: 10.21926/obm.icm.2202022

Mindfulness-based stress reduction (MBSR) teaches mindfulness meditation to reduce stress, anxiety, depression, and related forms of distress among a variety of patients. Much research has documented statistically significant reductions across a variety of self-report measures following MBSR, but researchers rarely assessed and reported the clinical significance of MBSR symptom reduction in accordance with specific criteria famously established by Jacobson and Truax [1]. Patients reporting symptoms of anxiety, depr [...]

by Ashley Schumaker  , Rachel Klauber  , Margaret Aasen  , Michael Padua  and Edwin Meresh

Received: 07 December 2021;  Published: 24 April 2022;  doi: 10.21926/obm.neurobiol.2202121

Catatonia and malignant catatonia may result in devastating and life-threatening complications like pulmonary embolisms, pneumonia, deep venous thrombosis, rhabdomyolysis, and even death. There have been documented cases implicating alcohol withdrawal as a significant culprit in catatonia. Here, we provide a unique case report of a patient with a complicated medical course, who subsequently developed malignant catatonia secondary to severe alcohol withdrawal, and was successfully treated using both first line treat [...]

by Tomeu Rigo  and Sergi Castillo

Received: 28 October 2020;  Published: 14 April 2021;  doi: 10.21926/aeer.2102004

The Metropolitan Area of Barcelona is a densely populated region in the North-East of the Iberian Peninsula. Infrastructures in this area play a significant role in the economy of this part of Europe. The combination of the Mediterranean Sea and the complex topography is responsible for the occurrence of severe weather events in this location and the surrounding areas. The use of remote sensing data in an hourly resolution allows the identification and characterization of those severe episodes, helping in determini [...]

by Siera Sylvester  , Jalaycia Hughes  and Clayton Clark II

Received: 23 March 2022;  Published: 07 June 2022;  doi: 10.21926/aeer.2202023

Building performance is often expressed according to primary energy use; however studies should also include environmental load. To mitigate the effects of increased CO2 emissions, green building designs are now increasingly popular options for stakeholders. In contrast, impacts of green design parameters, building performance assessment, and design optimization objectives are not addressed sufficiently for American infrastructure. Designing low-energy architecture to minimize carbon emissions requires thoughtful a [...]

by Adolfo Toledano-Díaz  , Ma Isabel Álvarez  and Adolfo Toledano

Received: 18 December 2019;  Published: 09 May 2020;  doi: 10.21926/obm.geriatr.2002117

Neurons, from the time of their birth until their death, are always accompanied by neuroglial cells, maintaining very close morphological and functional relationships among themselves. Classically three main neuroglial families have been considered within the central nervous system (CNS): astroglia, oligodendroglia, and microglia. However, using morphological and immuno-cytochemical criteria, several different types/subtypes of neuroglial cells have been identified, each exerting specific physiological and patholog [...]