by Hannah O'Connor  , Joseph Biederman  , Maura DiSalvo  , Gagan Joshi  , Stephen V. Faraone  and Janet Wozniak

Received: 25 January 2024;  Published: 04 June 2024;  doi: 10.21926/obm.icm.2402031

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of <1 [...]

by Paul O'Hara

Received: 20 December 2023;  Published: 03 June 2024;  doi: 10.21926/rpm.2402012

The spin-statistics theorem is generalized to include quantum entanglement. Specifically, within the context of spin entanglement, we prove that isotropically spin-correlated (ISC) states must occur in pairs. This pairing process can be composed of parallel or anti-parallel states. Consequently, the article proposes using ISC states as a unifying principle to explain better Bose-Einstein condensates, the theory of superconductivity, and molecular and atomic orbitals, all of which involve a pairing process. The theo [...]

by Tatsuya Kin  , Hirofumi Noguchi  and Atsushi Kawaguchi

Received: 15 February 2024;  Published: 03 June 2024;  doi: 10.21926/obm.transplant.2402216

Using donation after circulatory determination of death (DCD) donors has been shown to be a potential means of increasing the number of donors for organ transplantation. The purpose of this study was to examine the published practice of DCD in Japan to properly define their practice as controlled or uncontrolled. Through the Web of Science database, we systematically searched articles describing uncontrolled DCD, controlled DCD or Maastricht classification. A total of 12 articles (ten articles related to kidney, on [...]

by Upasana Ramphal  , Derek Tshiabuila  , Yajna Ramphal  , Jennifer Giandhari  , Carel van Heerden  , Cheryl Baxter  , Stephanie van Wyk  , Sureshnee Pillay  , Oluwakemi Laguda-Akingba  , Eduan Wilkinson  , Richard Lessells  and Tulio de Oliveira

Received: 01 March 2024;  Published: 30 May 2024;  doi: 10.21926/obm.genet.2402239

During the SARS-CoV-2 pandemic, next-generation sequencing (NGS) technologies like the Ion Torrent S5 and Illumina MiSeq, alongside advanced software, improved genomic surveillance in South Africa. This study analysed anonymized samples from the Eastern Cape using Genome Detective and NextClade, showing Ion Torrent S5 and Illumina MiSeq success rates of 96% and 94%, respectively. The study focused on genomic coverage (above 80%) and mutation detection (below 100), with the Ion Torrent S5 achieving 99% coverage comp [...]

by Melissa Scollan-Koliopoulos  , Donna Naturale  , Brynn Mahurter  , Sara Curren  and Ryan J. Koliopoulos

Received: 03 February 2024;  Published: 29 May 2024;  doi: 10.21926/obm.geriatr.2402280

There is not enough information regarding the impact of stigma associated with a. diagnosis of diabetes in aging older adults. Perceptions of diabetes are passed down generationally and may be influenced by mainstream societal perceptions at the time the perception is shaped. This is known as a multigenerational legacy of diabetes for those with whom the perceptions are shaped within families when a hereditarily predisposed condition occurs. In this study, participants over the age of (n = 88) 60 years old were adm [...]

by Alessandro Stasi  and Onnida Thongpravati

Received: 04 March 2024;  Published: 29 May 2024;  doi: 10.21926/obm.genet.2402238

The expansion of do-it-yourself (DIY) gene editing, facilitated by Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technology, has catalyzed a significant shift in scientific research and biotechnology innovation. This movement is propelled by a community-driven approach that challenges the traditional confines of scientific exploration, allowing amateur scientists to perform sophisticated biological experiments. While this democratization fosters inclusivity and accelerates innovation, it simult [...]

by Ahmad R. Alsayed  and Andi Dian Permana

Received: 28 February 2024;  Published: 28 May 2024;  doi: 10.21926/obm.genet.2402237

Bacteriophages, or phages, are viruses that infect bacteria, exhibiting specificity towards particular bacterial strains. Despite being overshadowed by traditional antibiotics in the West, interest in phage therapy has resurged due to the escalating antimicrobial resistance crisis. Understanding phage biology, selection, production, and pharmacology is crucial for their clinical application. Phages interact intricately with the human microbiome, influencing bacterial populations and potentially offering therapeutic [...]

by R. Lalitha S. Fernando  and M.K.M. Natharka Rushan

Received: 25 December 2023;  Published: 28 May 2024;  doi: 10.21926/aeer.2402013

Ensuring the sustainability of hospital waste management practices has become a burning issue. Due to the growing population coinciding with rapid urbanization and industrialization, practicing sustainable methods of medical waste management is an urgent requirement. Like other developing countries, Sri Lanka also faces various difficulties when dealing with high-risk hospital waste material, spreading diseases rapidly and making the environment unclean. Thus, moving towards sustainable hospital waste management ha [...]

by Emily Smith Schafer

Received: 02 March 2023;  Published: 24 May 2024;  doi: 10.21926/obm.icm.2402030

According to the National Survey of Children’s Health (NSCH), nearly 30 million children in the United States have experienced one or more types of significant childhood trauma. In the average public school, this statistic translates to as many as half of the students in a given teacher’s classroom. Children exposed to the toxic stress of trauma often experience negative consequences that affect their academic, psychological, socioemotional, and behavioral health. To aid educators in addressing this reality, trauma [...]

by Emad Fadhal

Received: 18 January 2024;  Published: 24 May 2024;  doi: 10.21926/obm.genet.2402236

The RAS signaling pathway is a crucial cell transduction pathway central to transmitting signals from outside the cell to the cell nucleus and influencing fundamental biological mechanisms like cell growth, division, and specialization. This signaling pathway has recently received much attention in scientific research because of its involvement in various diseases, especially carcinogenesis. Our study identified the significance of crucial proteins in the RAS signaling cascade in cancer development and progression. [...]

by Mubashir Zafar

Received: 13 March 2024;  Published: 24 May 2024;  doi: 10.21926/obm.neurobiol.2402225

The increasing prevalence of mental health issues among university students has become a growing concern globally. This review explores the potential of Artificial Intelligence (AI) integrated with principles of behaviour therapy to address mental health challenges among university students. The paper examines how AI technologies, including chatbots, virtual reality, and machine learning algorithms, can be harnessed to provide accessible, personalized, and effective mental health interventions. Furthermore, it disc [...]

by Syd Hiskey  and Neil E Clapton

Received: 07 April 2024;  Published: 21 May 2024;  doi: 10.21926/obm.icm.2402029

The work of psychotherapy demands much of those who engage in it. Compassion provisioned by therapists requires varying competencies, yet remains a highly embodied and enactive endeavour. Therapist skill can be cultivated in this area and enhanced through a variety of body-mind trainings, including various forms of therapist personal practice. However, much clinical training/continued professional development centres on education workshops, emphasising knowledge above skill. Given this we present feasibility data f [...]

by Yang Eun Kim  and Boram Lee

Received: 07 March 2024;  Published: 21 May 2024;  doi: 10.21926/obm.neurobiol.2402224

Preschool teachers are at high risk of depression. Therefore, emphasis should be placed on evaluating a valid and reliable instrument to measure depressive symptomatology for this population. One such promising instrument is the Beck Depression Inventory (BDI-II), a 21-item self-report measure designed to assess the presence and severity of depression. Although the tool’s psychometric properties have been analyzed in different samples, they have not been validated with a Korean preschool teacher sample. Hence, this [...]

by Ana Valado  , Márcia Morais  , Stephanie Fortes  , Joana Rosado  , João Paulo Figueiredo  and Armando Caseiro

Received: 20 November 2023;  Published: 21 May 2024;  doi: 10.21926/obm.icm.2402028

Hydrotherapy is highly recommended for older adults because it offers warmth and support, so people with pain or reduced mobility and balance can move and exercise more freely compared to regular physical activity. The high plasma antioxidant capacity of uric acid in neutralizing oxidative species and the importance of nitric oxide (NO) in vasodilation and inflammatory response are relevant in older adults. This work aimed to evaluate hydrotherapy's effect on uric acid and NO concentrations in a population aged ≥ 6 [...]

by Faten Dhawi

Received: 20 February 2024;  Published: 20 May 2024;  doi: 10.21926/obm.genet.2402235

Pearl millet (Pennisetum glaucum), a vital cereal crop renowned for its drought tolerance, is a cornerstone for smallholder farmers in arid and semi-arid regions, ranking as the fifth most significant cereal globally. Despite its resilience, the molecular mechanisms underlying its tolerance to heat stress remained elusive. To address this knowledge gap, we subjected ten-day-old pearl millet seedlings to an unprecedented temperature of 50°C for 60 seconds. Subsequent next-generation RNA sequencing aimed to unrav [...]

by Salah Vaisi  , Honia Modares Gorji  and Narmin Shafei

Received: 07 January 2024;  Published: 17 May 2024;  doi: 10.21926/aeer.2402012

Visual comfort affects the quality of classrooms as well as student learning. A practice-oriented approach discovers how the gap between academic research and its application in building design can be addressed. Nevertheless, the physical characteristics design of daylighting systems, including window sizes, shapes, dimensions, and materials, are considered fundamental challenges for their practicability. In this study, the physical characteristics design of daylighting systems, including window sizes, shapes, dime [...]

by Gerhard Litscher

Received: 14 May 2024;  Published: 15 May 2024;  doi: 10.21926/obm.icm.2402027

Laser acupuncture, a rising complementary therapy, applies a low-intensity laser to acupuncture points, yet its underlying mechanisms remain unclear. Proposed hypotheses include modulation of cellular signaling, tissue repair, and immune modulation. Laser acupuncture may stimulate energy flow, neurotransmitter release, cellular changes, immune regulation, and neuroendocrine activity. Additionally, the biophoton theory suggests an involvement of ultra-weak photon radiation from cells. Litscher et al. explore these m [...]

by Tülin Avcı Hansu

Received: 25 December 2023;  Published: 15 May 2024;  doi: 10.21926/cr.2402005

In this study, by producing bifunctional material, hydrolysis, and supercapacitor applications were investigated. The carbon nanotube-supported Pt catalyst was prepared using the sodium borohydride (NaBH4) reduction. Surface characterization of the synthesized Pt/CNT catalyst was performed using scanning electron microscopy-energy dıstrıbutıon X-ray spectrometer (SEM-EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). Hydrolysis experiments were performed after deciding on the appropriate ato [...]

by Adrian Krzysztof Antosik  , Karolina Mozelewska  and Marcin Bartkowiak

Received: 29 February 2024;  Published: 13 May 2024;  doi: 10.21926/jept.2402012

The investigation aimed to delve into the intricate relationship between the presence of titanium dioxide and the resulting alterations in the adhesive's behavior under different conditions. The focus extended beyond mere observation to understand how these additives interact with the adhesive matrix, potentially imparting beneficial attributes. Notably, the study delved into the optimization of thermal stability, the extension of the adhesive's functional lifespan, and the mitigation of shrinkage tendencies. This [...]

by Gilbert Ahamer

Received: 07 December 2023;  Published: 13 May 2024;  doi: 10.21926/jept.2402011

The present need for an energy transition in the wake of a global climate catastrophe led to the “EU green deal” which requires a transition of the energy system in all countries. This study aimis survey aims to identify strategies within such an energy transition based on global trend analyses and reports on available technologies for implementation. Based on a literature analysis of over 300 pieces (of feasibility studies and technology implementation reports with a focus on Central Europe) and a statistical anal [...]

by Tracy O'Halloran  , Jennifer Symonds  and Linda Bhreathnach

Received: 02 November 2023;  Published: 11 May 2024;  doi: 10.21926/obm.icm.2402026

This systematic review examined the impact of wellbeing interventions on the anxiety levels of children attending low-income schools. Studies, published between January 2000 and April 2022, were included if they had samples of school aged children attending low-income schools who were given a universal school-based wellbeing intervention. Ten databases were searched systematically to identify 542 records. After title and abstract screening, 43 records remained for full text screening, and of these studies, 10 met i [...]

by Anna Koczwara  , Lingfan Jiang  and Shasha Zheng

Received: 29 November 2023;  Published: 11 May 2024;  doi: 10.21926/rpn.2402009

Gout is an increasing metabolic disease due to the buildup of uric acid. The buildup of uric acid due to inadequate excretion leads to uric acid crystal formation. Treatment for gout aims to eliminate the uric acid crystal formation so that inflammation decreases. Traditional gout medication is usually allopurinol, but increasing studies have proven that herbal remedies may be promising. Over the past few years, studies have demonstrated that Simiao powder, a traditional Chinese medicine (TCM), is more effective th [...]

by Shourjo Chakravorty  and Ashka Patel

Received: 21 November 2023;  Published: 10 May 2024;  doi: 10.21926/obm.transplant.2402215

Transplanted lung allografts are particularly susceptible to infection among SOT due to the constant exposure to the environment, aggressive immunosuppressive strategies, and impaired clearance mechanisms after denervation of the transplanted lung. Though prophylactic antimicrobial, antifungal, and antiviral regimens are used as preventive strategies to mitigate the risk of infection, complications related to allograft infection remain one of the primary causes of morbidity and mortality after lung transplantation. [...]

by Leonel Pereira  and Ana Valado

Received: 06 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.neurobiol.2402223

This review explores the potential of compounds derived from red algae (Rhodophyta) as promising neuroprotective agents for treating neurodegenerative disorders. Red algae, abundant in marine environments, contain bioactive compounds with diverse chemical structures and functionalities. Sulfated polysaccharides, primarily agar and carrageenans, stand out as the predominant and widely utilized compounds derived from red algae. Additionally, red algae harbor a spectrum of potential molecules such as essential fatty a [...]

by Shashya Wijesinghe  and Elizabeta B. Mukaetova-Ladinska

Received: 03 March 2024;  Published: 10 May 2024;  doi: 10.21926/obm.geriatr.2402279

In the UK, 25,000 people from ethnic minority background live with dementia. Although dementia associated risk factors are common amongst South Asians, they tend to present at services later and when in crisis. This review explores UK South Asian communities perception of dementia to understand factors impacting their decision to seek help. Search terms assisted by the PICO strategy were inputted into five databases and ten qualitative papers identified. Meta-ethnography methodological framework was implemented for [...]