by Danielle Gentile  , Danielle Boselli  , Matthew Flores  , Susan Yaguda  , Rebecca Greiner  , Paulomi Campbell  and Chasse Bailey-Dorton

Received: 31 October 2019;  Published: 21 February 2020;  doi: 10.21926/obm.icm.2001008

Literature suggests Oncology Massage (OM) reduces anxiety. However, research is limited in large, diverse, nonexperimentally manipulated outpatient samples of cancer patients. The purpose of this study was to 1) describe OM visit patterns, 2) describe anxiety response to OM, and 3) determine if OM resulted in significantly reduced anxiety at first visit, across all visits, and longitudinally over time controlling for demographic factors. From January 2015-June 2019, a cohesive, consecutive, retrospective sample eva [...]

by Peter Bauer  , Gabriele Wildhardt  , Dieter Gläser  , Clemens Müller-Reible  , Hanno J. Bolz  , Hanns-Georg Klein  , Ulrich Finckh  and Ute Hehr

Received: 24 September 2017;  Published: 28 April 2018;  doi: 10.21926/obm.genet.1802019

On behalf of the German Society of Human Genetics, we present guidelines for molecular genetic diagnostic testing using high-throughput technology, such as next-generation sequencing (NGS). These guidelines have been formulated by an expert group and reviewed by members of the German Society of Human Genetics. Building on the existing EuroGentest guidelines for diagnostic NGS, these updated guidelines incorporate additional aspects and country-specific topics. New considerations include the introduction of a check [...]

by Luis Delaye

Received: 05 May 2019;  Published: 11 July 2019;  doi: 10.21926/obm.genet.1903083

Background: Phylogenetic analysis shows that Pneumocystis have coevolved with their mammalian hosts for millions of years. As a result, infection by Pneumocystis is species specific (i.e. a given Pneumocystis species can infect only a single species of host). This specificity suggests the existence of a Red-Queen dynamic between Pneumocystis and its host. Evidence of this dynamic is provided by the molecular diversity and the elevated rate of non-synonymous versus synonymous (dN/dS) codon substitutions among Pneumo [...]

by Francisco V. Muñoz  and Linda Larkey

Received: 20 May 2020;  Published: 27 July 2020;  doi: 10.21926/obm.icm.2003035

Breast cancer survivors (BCSs) report decrements in cognitive functioning. A Meditative Movement (MM) program (Qigong/Tai Chi Easy) combines meditation and exercise, practices known to improve cognitive function. Method: Using a single group, pre- to post-intervention assessment design, a pilot study was conducted in BCSs to test the effects of an 8-week MM intervention on cognitive functioning, sleep and mood and to explore changes on selected gene expression factors, BDNF, NF-kB1, and TP53, expected to improve wi [...]

by Dean M. Cordingley  and Stephen M. Cornish

Received: 30 May 2022;  Published: 07 October 2022;  doi: 10.21926/obm.geriatr.2204206

Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of maintaining skeletal muscle strength, mass, and function with aging. Sarcopenia is exacerbated with increased age and therefore, it is important to understand the potentia [...]

by Rui Wang  , Dong Lin  , Minghuan Gao  , Linna Guo  , Tiesheng Li  and Minghua Liu

Received: 29 January 2022;  Published: 07 April 2022;  doi: 10.21926/cr.2202008

A series of novel Bi2MoO6/Ag/Ag2CrO4 heterostructure photocatalysts (denoted as BA-X, X = 1, 3, 5, 10) were synthesized using a coprecipitation method. These photocatalysts were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-vis spectroscopy, and X-ray photoelectron spectroscopy (XPS) and their photocatalytic properties were investigated. Compared with pure Bi2MoO6 or Ag2CrO4, BA-5 exhibited a higher photocatalytic property and broader light absorption. In addition, the surface pla [...]

by Sylvie Bonin-Guillaume  and Patrice Rat

Received: 09 July 2020;  Published: 07 December 2020;  doi: 10.21926/obm.geriatr.2004141

Acute or persistent pain is a common occurrence and is often undertreated in older patients, especially those with an inability to communicate verbally (ICV). Regular comprehensive pain assessment, including self-rating and/or behavior scales, is critical but difficult to implement in routine clinical practice. The choice of the most appropriate scale for each patient is not easy, even for trained and skilled medical personnel. Indeed, the use of scales for short pain-behavior exposes to pain under-detection due to [...]

by Chang Gu  , Hongmei Gu  , Meng Gong  and Janet Blackadar

Received: 21 April 2022;  Published: 05 August 2022;  doi: 10.21926/rpm.2203014

Mass timber products (MTPs) are being adopted in new building constructions and remodels in the last three decades, credited to their renewable and low carbon footprint characteristics. However, there are no mass timber manufacturers currently existing in Atlantic Canada. Extended distances of transporting MTPs to this region from other Canadian provinces may sacrifice the environmental benefits of using MTPs. This study was aimed to understand, via conducting a cradle-to-gate life cycle assessment (LCA), the envir [...]

by Sylvie Langlois  and R Douglas Wilson

Received: 01 August 2017;  Published: 26 September 2017;  doi: 10.21926/obm.genet.1703007

Prenatal genetic aneuploidy screening approaches are designed to identify pregnant patients at increased risk of having a fetus affected. Conventional prenatal screening has consisted in providing women a risk estimate of having a pregnancy affected with trisomy 21 or trisomy 18 based on maternal age and analysis of serum markers and ultrasound nuchal translucency (NT) measurement. In 2011, the introduction of cell-free DNA (cfDNA) based screening into clinical practice has provided new options for aneuploidy scree [...]

by Edda Cava  , Alessandro Collo  , Marcella Serioli  and Sergio Riso

Received: 30 June 2020;  Published: 12 October 2020;  doi: 10.21926/obm.neurobiol.2004073

We report, for the first time, the case of amyotrophic lateral sclerosis (ALS) onset in a 54-year-old woman not following a strict gluten-free diet (GFD) for six years after the diagnosis of celiac disease (CD). The patient did not display any sign of gluten toxicity, malabsorption, or CD-related comorbidity. Previous cases reported in medical literature showed ALS-like forms secondary to gluten intolerance, with symptom remission after a strict GFD. Even after correcting dietary flaws, the clinical manifestation o [...]