Table of Content

Open Access Review

BK Virus-Associated Nephropathy in Adult Patients Post Kidney Transplantation: What Progress in 30 Years of History?

Received: 24 January 2024;  Published: 25 July 2024;  doi: 10.21926/obm.transplant.2403221

Abstract

Completely unknown before the 90s and exceptional up to the 2000s, BK virus nephropathy (BKvN), usually known as polyomavirus-associated nephropathy, has emerged as a significant and severe viral complication in kidney transplantation (KT). More than twenty years after Gardner's discovery of BKv in 1971, Purighalla described, in 1995, the first case of BKvN. Four years later in 1999, Nickeleit et al. published a first series of five cases of BKvN and made very precious and pertinent contributions to understanding t [...]

826 11230

Open Access Review

Advancements in Silkworm-Derived Silk Fibroin Biomaterials for Peripheral Nerve Regeneration

Received: 14 October 2022;  Published: 20 January 2025;  doi: 10.21926/obm.neurobiol.2501265

Abstract

Regenerating injured nerves is difficult because they have little spontaneous regeneration potential. Advances in tissue engineering and regenerative medicine have emphasized the possibility of biomaterial-based methods for nerve healing. Natural protein-based biomaterials have benefits over synthetic ones, such as biocompatibility, non-immunogenicity, and biodegradability. Silk fibroin, generated from mulberry and non-mulberry silkworms, is especially promising because of its abundance, simplicity of processing in [...]

1488 11224

Open Access Original Research

Promoting College Student and Staff Well-being Through a Mindfulness-based Coping Program

Received: 23 February 2023;  Published: 30 August 2023;  doi: 10.21926/obm.icm.2303034

Abstract

This study evaluated the impact on student and staff well-being of a mindfulness-based cognitive-behavioral coping program, Be REAL (Resilient Attitudes & Living), delivered by campus staff using a task-sharing approach. The program was adapted for online delivery during COVID19. Study participants included 325 undergraduate students and 100 staff members at a large tri-campus university in the U.S. Participants completed surveys with self-report measures assessing mindfulness, perceptions of stress, emotion regula [...]

1388 11212

Open Access Research Article

Synthesis of SAPO-34 Zeolite Membrane: Influence of Sources of Silica

Received: 03 October 2023;  Published: 11 December 2023;  doi: 10.21926/cr.2304030

Abstract

The research described the production and characterization of various materials, particularly alpha-alumina ceramic supports, zeolite SAPO-34, and zeolite membranes. Ceramic supports were manufactured through dry uniaxial compaction. Sintering of the supports was carried out at 1300°C for 2 h. SAPO-34 zeolites and zeolite membranes were synthesized through a hydrothermal process involving two steps: a first step at 38°C for 24 h and a second step at 200°C for 24 h. The research aimed to determine how different sili [...]

1525 11199

Open Access Review

Practical Review on the Impact of Celiac Disease on the Patient

Received: 05 August 2022;  Published: 13 February 2023;  doi: 10.21926/rpn.2301003

Abstract

Celiac disease (CD) is a multisystem immune-mediated disorder resulting in enteropathy of the small intestine with the ingestion of gluten, in genetically susceptible individuals. This condition impact 1% of the population and can result in the development of other conditions such as chronic fatigue, anemia, osteoporosis, aphthous stomatitis, elevated liver enzymes, joint pain, infertility, peripheral neuropathy, and epilepsy. In this review, we outline the clinical presentation of CD, the physiological differences [...]

1326 11193

Open Access Original Research

An Ab Initio Study of Li/Ni-doped NaxMeO2 Cathode Material for Na-Ion Batteries

Received: 02 November 2020;  Published: 10 June 2021;  doi: 10.21926/jept.2102022

Abstract

The current state-of-the-art quantum mechanics methodologies were applied to derive information on the bulk and surface properties of the P2-type layered oxide Na0.85Li0.17Ni0.21Mn0.64O2 (NLNMO), a cathode material. The special quasi-random structure (SQS) approach was employed to identify the arrangement of Li, Ni, and Mn ions in a supercell containing 115 atoms. Both the cell parameters and atomic positions were determined from DFT-PBE+U calculations to highlight specific distortions induced by the dopants (Ni an [...]

1972 11189

Open Access Review

RNA Editors and DNA Mutators: Cancer Heterogeneity Through Sequence Diversification

Received: 03 December 2018;  Published: 08 April 2019;  doi: 10.21926/obm.genet.1902072

Abstract

Cancer development and progression is strongly associated with somatic mutations. From oncogenic hits that initiate the primary tumor formation to metastasis, the tumor mutational burden (TMB) plays a prominent role in the disease progression for the vast majority of cancer types. Not only are heterogeneous mutational loads or genetic heterogeneity causal to transcriptomic and proteomic discrepancies and to phenotypic diversity between individuals, they are also between tumor cells. But in addition to mutations, a [...]

1626 11184

Open Access Original Research

Preparation of a Novel Bi2MoO6/Ag/Ag2CrO4 Catalyst with Promoted Visible Light Photodegradation of RhB Dye

Received: 29 January 2022;  Published: 07 April 2022;  doi: 10.21926/cr.2202008

Abstract

A series of novel Bi2MoO6/Ag/Ag2CrO4 heterostructure photocatalysts (denoted as BA-X, X = 1, 3, 5, 10) were synthesized using a coprecipitation method. These photocatalysts were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), UV-vis spectroscopy, and X-ray photoelectron spectroscopy (XPS) and their photocatalytic properties were investigated. Compared with pure Bi2MoO6 or Ag2CrO4, BA-5 exhibited a higher photocatalytic property and broader light absorption. In addition, the surface pla [...]

1573 11178

Open Access Review

Prenatal Screening for Fetal Aneuploidy

Received: 01 August 2017;  Published: 26 September 2017;  doi: 10.21926/obm.genet.1703007

Abstract

Prenatal genetic aneuploidy screening approaches are designed to identify pregnant patients at increased risk of having a fetus affected. Conventional prenatal screening has consisted in providing women a risk estimate of having a pregnancy affected with trisomy 21 or trisomy 18 based on maternal age and analysis of serum markers and ultrasound nuchal translucency (NT) measurement. In 2011, the introduction of cell-free DNA (cfDNA) based screening into clinical practice has provided new options for aneuploidy scree [...]

1718 11173

Open Access Concept Paper

Understanding the Functional Roles of Multi-Modal Processing and Gc Activation In Older People's Performance in Caregiving Training

Received: 05 October 2018;  Published: 25 December 2018;  doi: 10.21926/obm.geriatr.1804026

Abstract

The current article addresses the working memory constraints experienced by older people in caregiving training. Two different approaches aiming to free the older people’s working memory space were discussed. They include multi-modal visual processing and Gc activation. The emphasis was on the theoretical underpinnings of both approaches with empirical evidence from the research and literature to demonstrate their effectiveness in older people’s caregiving training. Further discussion was made with respect to the t [...]

1695 11161

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