by Lei Zhang  , Xian-Zhang Hu  , Xiaoxia Li  , Jacob Dohl  , Tianzheng Yu  and Robert J. Ursano

Received: 28 December 2018;  Published: 21 March 2019;  doi: 10.21926/obm.geriatr.1901041

Depression, PTSD, and hostility are common mental conditions that are associated with aging. A growing body of research has highlighted the possible effects of depression, PTSD, and hostility on aging and telomere length (TL), a cellular aging marker. Individuals who exhibit excessive responses to stressors show notable circulating inflammatory responses with high cortisol reactivity, which increases cell turnover and oxidative stress and may subsequently contribute to shortened TL. This review focuses on the most [...]

by Igor Val Danilov  , Sandra Mihailova  and Araksia Svajyan

Received: 05 July 2022;  Published: 28 September 2022;  doi: 10.21926/obm.neurobiol.2203137

This study aims to observe the differences in the shared intentionality magnitude in mother-child dyads with neurotypical (NT) children and neurodivergent (ND) children aged 3-6 years. The quality of shared intentionality in infancy is associated with cognitive development. Our results showed that ND children scored six times higher (on average) in quiz-test than NT children. Children with difficulties in interaction (ND children) are more likely to use shared intentionality in conversation than NT children. We bel [...]

by Mohamed Abutineh  , Nicholas Pizzo  , Nicholas Nifakos  , Xiao-Lu Jin  , John M Harlin  and Xing-Hai Zhang

Received: 26 October 2020;  Published: 18 February 2021;  doi: 10.21926/obm.genet.2101124

Citrus is an important group of globally produced fruit crops, holding great economic, cultural, and health value. Belonging to the Rutacaeae family, the genus Citrus includes some of the most iconic and widely appreciated variants of fruits such as the orange, lemon, lime, grapefruit, and tangerine. The spread of various diseases threatens the worldwide production of citrus fruit crops. Diseases such as Asiatic citrus canker, citrus tristeza virus, citrus leprosis, and especially citrus greening disease (also know [...]

by Zheer Al-Mashhadi  , Rikke Viggers  , Rasmus Fuglsang-Nielsen  , Bente Langdahl  , Peter Vestergaard  , Søren Gregersen  and Jakob Starup-Linde

Received: 02 April 2020;  Published: 18 June 2020;  doi: 10.21926/obm.geriatr.2002123

Type 2 diabetes mellitus (T2DM) and osteoporosis are two major public health concerns worldwide, contributing to morbidity and mortality in the elderly. Aging is one of the most significant risk factors for low bone mass, bone fragility, and fractures. Among the several comorbidities that affect the elderly with diabetes, increased fracture risk is a relatively recently discovered complication. Generally, individuals with T2DM exhibit higher bone mineral density, which complicates the assessment of fracture risk. D [...]

by Jeamichel Puente Torres  , Harold Crespo Sariol  , Thayset Mariño Peacok  , Ángel Brito Sauvanell  , Greet Cuyvers  , Guy Reggers  , Pieter Samyn  , Dries Vandamme  , Jan Yperman  , Peter Adriaensens  and Robert Carleer

Received: 25 October 2022;  Published: 21 April 2023;  doi: 10.21926/aeer.2302028

The chemical regeneration of exhausted granular activated carbon (GAC) from a water treatment plant to produce dialysis water used in hemodialysis treatments for chronic renal disease patients from a general Hospital of Ciego de Avila province, Cuba, was investigated. Activated carbon (AC) exhausted mainly by inorganics (Ca (Ca-chelates), Mg and Na) was regenerated using hydrochloric acid and acetic acid (one regeneration cycle). Solutions of 5%, 10%, 15% and 20%(v/v) as well as four contact times (2 h, 4 h, 6 h an [...]

by Jaclyn B. Murry  and Ying S. Zou

Received: 30 June 2022;  Published: 07 November 2022;  doi: 10.21926/obm.genet.2204168

Double aneuploidy is the co-occurrence of aneuploidy of two different chromosomes within the same individual. Genomic imbalance associated with two aneuploidies in humans is associated with early lethality, and observation in live-born humans is rare. In isolation, trisomy of chromosomes 13, 18, 21, X, and Y may be better tolerated, whereas monosomy of X is the only such type of aberration that may be compatible with life. It is hypothesized that two successive malsegregation events must occur in early development [...]

by Naiwei Chi  , Shuyao Zheng  , Elwin Clutter  and Rong Wang

Received: 30 October 2019;  Published: 18 December 2019;  doi: 10.21926/rpm.1904007

Background:Diabetic patients suffer from chronic wounds partly due to altered function of fibroblasts. Fibroblasts of diabetic patients synthesize collagen I (COLI) at a much higher level than collagen III (COLIII), resulting in delayed tissue granulation and, consequently, a delay in the overall wound healing process. Methods:We aimed to revive the matrix protein productivity of diabetic fibroblasts by employing aligned, electrically conductive and biocompatible spider silk-CNT fibers as a cell culture matrix to m [...]

by Brenda T. Mbibueh  , Reeves M. Fokeng  and Suiven J.P. Tume

Received: 29 September 2021;  Published: 30 December 2021;  doi: 10.21926/aeer.2104038

Land-use change is one of the main indicators of soil quality. Soil physical and chemical properties vary with land use change and altitude as inferred from transect surveys and toposequences. Soil nitrogen, phosphorus, and potassium (NPK) are essential macronutrients for plant growth and soil nutrient balance. Their presence in the soil in appropriate quantities is important for maintaining crop yields and farmers income, particularly in developing countries where resources of soil chemical additives may be limite [...]

by Tyrone Pretorius  and Anita Padmanabhanunni

Received: 01 May 2022;  Published: 17 August 2022;  doi: 10.21926/obm.neurobiol.2203132

An important mental health concern arising from the COVID-19 pandemic was the loneliness resulting from the lockdown measures taken by many countries due to the outbreak. Thus, loneliness needs to be studied in detail for intervention purposes. The UCLA Loneliness Scale is the most widely used measure of loneliness. However, the 20-item measure has some drawbacks, including questionnaire fatigue, especially when used with other measures, and a lack of accurate responses to all items. In this study, we evaluated two [...]

by Arksarapuk Jittirat  , Natsuki Eguchi  , Natthavat Tanphaichitr  , Myreen Tomas  , Praveen Gundelly  , Kai Zhao  , Leal Herlitz  , Yasolatha Chalicheemala  , Himabindu Yerneni  , Rachel C. Forbes  , Beatrice P. Concepcion  and Ekamol Tantisattamo

Received: 02 May 2021;  Published: 07 February 2022;  doi: 10.21926/obm.icm.2201007

The novel coronavirus disease 2019 (COVID-19) pandemic has significantly impacted kidney transplantation worldwide. The rate of kidney transplantation decreased during the peak of the COVID-19 pandemic, especially living donor kidney transplantation. Kidney transplant recipients are at high risk of developing severe complications from COVID-19 due to underlying comorbidities and immunosuppressed status. Management of immunosuppression, including the induction therapy and maintenance immunosuppressive regimen, has b [...]