by Suman Mishra  , Kerry Bentley-Hewitt  , Alex Lubransky  , Bernard Venn  , Duncan Hedderley  , Hannah Dinnan  , Sheridan Martell  , Jillian Haszard  and John Monro

Received: 22 December 2021;  Published: 25 February 2022;  doi: 10.21926/rpn.2201006

People with pre-diabetes may be reluctant to add fruit to their diets due to concerns around sugars. Our objective was to measure outcomes associated with potential adverse effects of ingesting fruit sugars while assessing metabolic benefits from eating nutrient-rich kiwifruit. Thirty-four people with pre-diabetes were randomized to receive two kiwifruit or 250 mL bottled water per day for 12-weeks; two people withdrew. The primary outcomes were between-group differences for glycated haemoglobin (HbA1c) and plasma [...]

by Scott A. Campbell  , Matthew Hubert  , Janyne Johnson  , Nicole Salamon  and Peter E. Light

Received: 12 March 2019;  Published: 26 June 2019;  doi: 10.21926/obm.transplant.1902069

Background: One of the goals of clinical islet transplantation is to achieve a single-donor transplant that is dependent on obtaining enough quality β cell mass from one donor pancreas. Human islets are routinely cultured prior to transplantation, and pro-survival factors such as GLP-1 analogues have been reported to maintain β cell mass and survival. Interestingly, human islets may secrete GLP-1 and they also express the enzyme DPP4 that proteolytically cleaves GLP-1 into an inactive form. The aim of [...]

by Niccolo Caldararo

Received: 19 October 2021;  Published: 11 January 2022;  doi: 10.21926/obm.genet.2201145

The evolution of hominins, members of the zoological tribe Hominini, has been a much-studied topic, and the construction of phylogenetic trees has been the key method in molecular evolutionary studies. How scientists determine the phylogenetic trees are governed by the assumptions they place on the construction of similarities and differences in morphological traits, the differences in the number of base pairs in the genomes, and the number of similar gene clusters that code for traits (haplotypes) or are error seq [...]

by Pietro Gareri  , Antonino Maria Cotroneo  , Giuseppe Orsitto  , Nicola Veronese  and Salvatore Putignano

Received: 12 September 2021;  Published: 08 March 2022;  doi: 10.21926/obm.geriatr.2201193

Certain previous studies have demonstrated the benefits of the addition of citicoline, a cholinergic precursor, to acetylcholinesterase inhibitors (AchEIs) or memantine in patients with Alzheimer's disease (AD). The present study showed the effectiveness of oral citicoline plus AchEIs plus memantine in outpatients with AD. This was a retrospective case-control study involving 169 patients aged 65 years old or older having AD (mean age: 78.7 ±4.9 years). In addition, 84 patients were treated with AchEIs plus [...]

by Wolfgang Rennert  , Katie Cormier  and Samantha Sprott

Received: 22 November 2021;  Published: 24 December 2021;  doi: 10.21926/obm.transplant.2104156

Bone marrow transplants remain an import source of hematopoietic stem cells for patients suffering from specific diseases like aplastic anemia, for pediatric patients with malignant and non-malignant blood cell disorders, and for situations in which graft-versus-host disease (GvHD) is a concern. Identifying the optimal donor to achieve a 3-5 x 108/kg of recipient weight TNC yield may be challenging. In an analysis of 687 consecutive donors, donor and procedure characteristics were related to TNC/kg of recipient wei [...]

by Edmundo S. Valerio Neto  , Caio V.S. Almeida  , Giancarlo R. Salazar-Banda  and Katlin I.B. Eguiluz

Received: 24 November 2023;  Published: 11 March 2024;  doi: 10.21926/cr.2401003

In this study, we synthesized Pt-Rh nanowires (NWs) through chemical reduction of metallic precursors using formic acid at room temperature, excluding the use of surfactants, templates, or stabilizing agents. These NWs were supported on two substrates: carbon (Vulcan XC-72R) and carbon modified with tin oxide (SnO2) via the sol-gel method (10 wt.% SnO2). We explored the electroactivity of Pt/SnO2/C, Pt-Rh/C, Pt-Rh/SnO2(commercial)/C (commercial SnO2), and Pt-Rh/SnO2/C NWs toward electrochemical oxidation of ethanol [...]

by Satoshi Migita  and Tomoya Yamaguchi

Received: 18 September 2019;  Published: 14 January 2020;  doi: 10.21926/rpm.2001003

The surface roughness of titanium could regulate various cellular functions such as survival and growth. In the context of cell adhesion to materials, cell spreading and cell shape are also closely linked to various cellular functions. Previously, we found that Ti substrate with a 100-nm scale surface roughness reduced cell survival. However, effects of surface roughness on cell shape were not investigated. Herein, we quantified the initial adhesion behavior of osteoblasts on a Ti substrate with ~100 nm scale surfa [...]

by Jeamichel Puente Torres  , Harold Crespo Sariol  , Thayset Mariño Peacok  , Ángel Brito Sauvanell  , Greet Cuyvers  , Guy Reggers  , Pieter Samyn  , Dries Vandamme  , Jan Yperman  , Peter Adriaensens  and Robert Carleer

Received: 25 October 2022;  Published: 21 April 2023;  doi: 10.21926/aeer.2302028

The chemical regeneration of exhausted granular activated carbon (GAC) from a water treatment plant to produce dialysis water used in hemodialysis treatments for chronic renal disease patients from a general Hospital of Ciego de Avila province, Cuba, was investigated. Activated carbon (AC) exhausted mainly by inorganics (Ca (Ca-chelates), Mg and Na) was regenerated using hydrochloric acid and acetic acid (one regeneration cycle). Solutions of 5%, 10%, 15% and 20%(v/v) as well as four contact times (2 h, 4 h, 6 h an [...]

by Audrey Vanhaudenhuyse  , Anne-Sophie Nyssen  and Marie-Elisabeth Faymonville

Received: 14 February 2020;  Published: 09 May 2020;  doi: 10.21926/obm.icm.2002028

Hypnosis is a modified state of consciousness widely used to decrease pain perception in research protocols and clinical practice. In recent decades, hypnosis has been increasingly proposed to patients to re-engage their resources and capacities to modulate pain and emotional distress and to improve their treatment and recovery of well-being. Neuroimaging research helps clinicians to understand better how hypnosis works in terms of brain modulation. Hypnotic suggestions dramatically influence the self and environme [...]

by Gerald P. Morris

Received: 22 February 2019;  Published: 11 April 2017;  doi: 10.21926/obm.transplant.1701002

(1) Background: Lung transplantation is an increasingly utilized treatment for end-stage lung disease. Scarcity of organ donors limiting transplantation underscores the importance of optimal histocompatibility testing approaches to facilitate organ allocation and avoid immunologic rejection. Significant data has emerged over the past decade to define the role of alloantibodies against HLA in the pathogenesis of post-lung transplant complications. (2) Methods: Medical literature from 1996–2016 related to search term [...]