Table of Content

Open Access Review

Mechanisms and Approaches for Salt Tolerance in Turmeric: A Breeding Perspective

Received: 22 March 2022;  Published: 23 May 2022;  doi: 10.21926/obm.genet.2202154

Abstract

India is home to several medicinal herbs including turmeric. Turmeric is one of the major produces of India, primarily due to its unique and valuable medicinal and therapeutic properties. However, the growth and yield of turmeric are greatly affected by salt stress in certain parts of the country, especially those near water bodies where significant yield losses have been reported. To mitigate these losses caused by salt stress, certain plant breeding methods, transgenic approaches, and candidate genes along with i [...]

1851 13719

Open Access Review

Multimodal Pain Management of Liver Transplantation: What Is New?

Received: 14 May 2023;  Published: 13 October 2023;  doi: 10.21926/obm.transplant.2304198

Abstract

Liver transplantation (LT) is a life-saving treatment representing the only viable option for patients suffering from end-stage liver disease (ESLD) or acute liver failure. Patients who undergo LT require a multidisciplinary approach to postoperative pain management. However, pain management in this context is often inadequately explored. Limited options exist for proper pain control in patients with hepatic failure, mainly due to the increased risk of kidney and multi-organ failure. In LT candidates, specific anal [...]

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Open Access Technical Note

Improving the HealthCare of People with Dementia beyond the Diagnosis: The “Carlo Poma Dementia Care Pathway” Study Protocol

Received: 31 October 2018;  Published: 27 February 2019;  doi: 10.21926/obm.geriatr.1901036

Abstract

The WHO global action plan on the public health response to dementia 2017-2025 stressed the need to have a comprehensive approach with deep interconnections and cross-cutting elements through several action areas. As the elderly population grows worldwide, the number of patients with dementia increases rapidly because age is an important risk factor for developing late-onset dementia. Currently, dementia syndrome represents a true emergency. Once a diagnosis of dementia was made, informal caregivers, patients and t [...]

1586 13709

Open Access Review

Reminiscence from Half a Century of Anti-Pneumocystis Drug Discovery and Development

Received: 12 September 2018;  Published: 06 December 2018;  doi: 10.21926/obm.genet.1804052

Abstract

My experiences with the identification and development of the anti-Pneumocystis drugs trimethoprim-sulfamethoxazole, dapsone and atovaquone are recounted. Attention is drawn to certain often-overlooked aspects of these drugs, including their concomitant effects against infections other than Pneumocystis, matters of dosing and adverse effects. During the past four decades several million people worldwide received chemoprophylaxis and treatment with these drugs for Pneumocystis jirovecii pneumonia. The population of [...]

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Open Access Original Research

Estimating Potential Cost Containment through Provision of Unplanned Institutional Respite Services to Support Home-Based Care within Japan’s Long-Term Care Insurance System

Received: 19 February 2019;  Published: 09 July 2019;  doi: 10.21926/obm.geriatr.1903061

Abstract

Background: Many informal caregivers providing at-home care to older family members want to continue serving as the primary caregiver if they get sufficient support. A key service enabling continued at-home care is access to unplanned respite care facilities for temporary institutional care on short notice and in emergencies. Methods: This study used city government survey results on service user satisfaction with the Japanese Long-Term Care Insurance (LTCI) system for a mid-sized, Japanese city. From this a range [...]

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Open Access Case Report

Chasing Bodily-Self Ghost: Interoception-Aided Hypnosis in the Treatment for Depersonalization-A Case Study

Received: 17 May 2022;  Published: 06 February 2023;  doi: 10.21926/obm.icm.2301012

Abstract

This paper aims to introduce a relatively novel approach for Hypnosis to treat Depersonalization-derealization Disorder (DPRD). Depersonalization is conceptualized as a disrupted interoceptive process disorder. Based on this conceptualization, Hypnotic intervention is tailored to counter the flawed process. It is exemplified by a case of a young man suffering from depersonalization disorder who couldn't bear looking at himself in the mirror. The hypnotic intervention used in this case is then explained by predictiv [...]

1506 13659

Open Access Original Research

The Effect of Rotor Radius Ratio on The Performance of Hybrid Vertical Axis Wind Turbine Savonius-Darrieus NREL S809

Received: 05 October 2022;  Published: 02 January 2023;  doi: 10.21926/jept.2301001

Abstract

This research aims to know the effect of the Rotor Radius Ratio on the performance of the hybrid Vertical Axis Wind Turbine Savonius-Darrieus NREL S809 model using the Computational Fluid Dynamics method. Two-bladed Savonius is used as an internal rotor, and three-bladed Darrieus NREL S809 as an external rotor. Turbine model performance is analyzed through the value of the Moment Coefficient and Power Coefficient. The result shows that the increase in the Rotor Radius Ratio value causes an increase in the initial M [...]

1650 13639

Open Access Review

A Review on Male Infertility and Herbal Medicine: Complementary and Alternative Therapies in Animal Models

Received: 27 September 2023;  Published: 06 March 2024;  doi: 10.21926/obm.genet.2401221

Abstract

Various factors contributing to male infertility include genetic determinants, hormonal/neurological imbalance, erectile/libido disorders, genital tract injuries, and toxic/ischemic testicular injuries. Herbs increase sperm count and quality parameters, as well as sexual performance in infertile men, through various mechanisms. For this purpose, efforts were made to investigate effective plants in treating infertility, focusing on those studied in animal research. In this review, we explored the latest findings fro [...]

1786 13630

Open Access Review

Current Evidence on the Role of Epigenetic Mechanisms in Migraine: The Way Forward to Precision Medicine

Received: 09 May 2018;  Published: 10 October 2018;  doi: 10.21926/obm.genet.1804040

Abstract

Interactions between genetic and environmental factors in migraine are well known and can potentially determine an individual’s susceptibility to disease and responsiveness to treatment. Consequently, several epigenetic studies have been conducted to determine if and how genes are activated or inactivated in response to a diverse range of environmental migraine triggers. The results, in turn, have helped elucidate how these factors can promote or inhibit migraine progression or therapeutic response and can guide de [...]

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Open Access Perspective

Compassion in Preregistration Nurse Education: An Integrated Review

Received: 07 March 2019;  Published: 13 June 2019;  doi: 10.21926/obm.icm.1902036

Abstract

The evolving, dynamic and challenging healthcare landscape requires that the art and science of nursing equip preregistration nursing students with the knowledge and skills to positively respond to these changes. Central to these students’ ability to demonstrate competence in the fundamentals of nursing care are core nursing attributes to meaningfully engage and attend to patients’ in delivering compassionate care and meeting their needs. The literature identifies the process of delivering compassionate care as a h [...]

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