Table of Content

Open Access Review

Using Acoustic Fields to Fabricate ECM-Based Biomaterials for Regenerative Medicine Applications

Received: 22 March 2020;  Published: 21 July 2020;  doi: 10.21926/rpm.2003018

Abstract

Ultrasound is emerging as a promising tool for both characterizing and fabricating engineered biomaterials. Ultrasound-based technologies offer a diverse toolbox with outstanding capacity for optimization and customization within a variety of therapeutic contexts, including improved extracellular matrix-based materials for regenerative medicine applications. Non-invasive ultrasound fabrication tools include the use of thermal and mechanical effects of acoustic waves to modify the structure and function of extracell [...]

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Open Access Original Research

Mindful Self-Compassion and Adult Learner Retention in Post-Compulsory Education

Received: 15 July 2018;  Published: 23 January 2019;  doi: 10.21926/obm.icm.1901004

Abstract

Background: Adult learners often engage in formal education because they want to create changes in their lives and are determined to succeed in their chosen field. However, they also come with emotional "baggage" of early educational experiences, frequently have to deal with a multitude of competing demands, have financial strain, may face a lack of support, illness and/or injury. In addition, they are often dealing with the challenges of unfamiliar academic work, competing deadlines and initially lack basic academ [...]

2339 15186

Open Access Review

Computational Modelling of Deep Brain Stimulation for Parkinson's Disease: A Critical Review

Received: 23 November 2020;  Published: 14 May 2021;  doi: 10.21926/obm.neurobiol.2102095

Abstract

We review the use of numerical and computational models to explore deep brain stimulation for Parkinson’s disease (DBS PD). It is a review for the modeler and those interested in PD DBS modelling methods and their value. The main model categories of active fiber, mean field, driving force, and volume of tissue activated are described as well as many modelling techniques. We give the basic requirements for a DBS PD model and current theories of DBS mechanism of action, PD etiology, and movement selection. The emphas [...]

2517 15163

Open Access Review

Thrombotic Microangiopathy in Solid Organ Transplantation

Received: 31 January 2024;  Published: 10 April 2024;  doi: 10.21926/obm.transplant.2402211

Abstract

Thrombotic Microangiopathy (TMA) is a syndrome characterized by microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. The presence of schistocytes on peripheral smear, a negative Coombs test, elevated lactate dehydrogenase, increased reticulocyte count and low haptoglobin are often the clues for MAHA. The microvascular process often targets vasculature in kidneys, brain, gastrointestinal system, heart, and skin. A timely diagnosis and treatment are often crucial to prevent severe end organ damage and death [...]

2761 15148

Open Access Original Research

Energy Policy Scenarios for Carbon Emissions in Road Passenger Transport in Austria up to 2050

Received: 23 June 2024;  Published: 06 December 2024;  doi: 10.21926/aeer.2404026

Abstract

The transport sector accounts for approximately 25% of CO2-emissions in the EU and Austria, primarily due to passenger car transport powered by fossil fuels. Replacing conventional cars with sustainable alternatives is crucial for reducing emissions, improving air quality, and mitigating climate change while decreasing vehicle kilometers driven. This study analyzes policy strategies for Austria’s road passenger transport sector up to 2050 to determine their potential for significant CO2 reduction. Four scenar [...]

1239 15137

Open Access Original Research

A Multi-Centric Single-Blind Randomized Placebo-Controlled Trial to Evaluate the Efficacy of the Individualized Homeopathic Intervention in Breast Fibroadenoma

Received: 17 October 2022;  Published: 16 May 2023;  doi: 10.21926/obm.icm.2302021

Abstract

The primary objective of this study was to evaluate the efficacy of homeopathic medicines in the reduction or resolution of breast fibroadenoma (FA) through ultrasound (US) assessment in intervention and control groups. The secondary objective was to compare the efficacy of the homeopathic intervention in single and multiple fibroadenomas. A single-blind, randomized, placebo-controlled pilot study was conducted from January 2014 to June 2018 at 4 research centers with 6 months of follow-up. Females in the age group [...]

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Open Access Research Article

GAPcare: The Geriatric Acute and Post-Acute Fall Prevention Intervention for Emergency Department Patients – A Qualitative Evaluation

Received: 21 August 2019;  Published: 10 October 2019;  doi: 10.21926/obm.geriatr.1904078

Abstract

Background: Three million US emergency department (ED) visits occur for falls each year. The mortality of falls is increasing and only one fourth of older adults report their fall to their primary care provider, suggesting that valuable preventative opportunities are missed. A fall prevention intervention initiated in the ED immediately after a fall has the potential to reduce subsequent falls, but ED providers lack the time and resources to complete fall risk assessments on their patients. GAPcare, the Geriatric A [...]

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Open Access Short Communication

Evolution of Psychosomatic Diagnosis: From Masked Depression to Somatic Symptoms and Related Disorders

Received: 02 December 2022;  Published: 22 March 2023;  doi: 10.21926/obm.geriatr.2301228

Abstract

This paper discusses the history and the concept of somatization from masked depression to somatic symptoms and related disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM). Evaluating the evolution of these terms and concepts along the time course is very interesting. DSM 5 revision was intended to increase the relevance of these concepts in the primary care setting. “Masked depression” is a form of depression in which somatic symptoms or behavioral disturbances dominate the clinical pictur [...]

2259 15131

Open Access Case Report

Chasing Bodily-Self Ghost: Interoception-Aided Hypnosis in the Treatment for Depersonalization-A Case Study

Received: 17 May 2022;  Published: 06 February 2023;  doi: 10.21926/obm.icm.2301012

Abstract

This paper aims to introduce a relatively novel approach for Hypnosis to treat Depersonalization-derealization Disorder (DPRD). Depersonalization is conceptualized as a disrupted interoceptive process disorder. Based on this conceptualization, Hypnotic intervention is tailored to counter the flawed process. It is exemplified by a case of a young man suffering from depersonalization disorder who couldn't bear looking at himself in the mirror. The hypnotic intervention used in this case is then explained by predictiv [...]

1815 15130

Open Access Review

The Science of the “Simile”

Received: 20 April 2021;  Published: 11 August 2021;  doi: 10.21926/obm.icm.2103023

Abstract

Homeopathy is often attacked with claims of not being evidence-based or for the implausible nature of its major principles of dilution/potentization and/or the similars (“similia similibus curentur”). However, these statements have already been falsified on the experimental ground, besides being incorrect on an epistemological level. Here we provide an updated appraisal of the scientific approach to the principle of Similars and homeopathy, focusing on laboratory models. After a brief historical introdu [...]

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