by Kamyar Afshar  , Michelle Bremer  , Bharath Ravichandran  , Ashley A. Feist  , Eugene Golts  , Elizabeth H. Schonhoft  and Gordon Yung

Received: 14 July 2021;  Published: 15 October 2021;  doi: 10.21926/obm.transplant.2104153

Alpha-1 antitrypsin deficiency (AATD) accounts for approximately 5% of lung transplants (LTx) performed annually. No studies have addressed the potential benefit of ongoing alpha-1 proteinase inhibitor (A1-PI) replacement to AATD patients post-LTx. Our primary objective was to assess potential benefits of continually administering A1-PI from pre- to post-transplantation for AATD LTx recipients. A retrospective case series was performed on AATD LTx recipients between 2002 and 2018. Data reviewed included date of A1- [...]

by Kenneth Lundstrom

Received: 01 October 2019;  Published: 28 November 2019;  doi: 10.21926/obm.genet.1904099

Epidemiological data and meta-analysis have confirmed that there exists a strong association between nutrition and disease risk. In the context of cancer, it has been demonstrated that unhealthy diets increase the risk of disease. On the other hand, major dietary interventions and lifestyle changes have been demonstrated to provide therapeutic efficacy in cancer patients. Genetic mechanisms have been reported to be associated with cancer development induced by environmental and nutritional factors. Genetics plays a [...]

by Jeamichel Puente Torres  , Harold Crespo Sariol  , Thayset Mariño Peacok  , Ángel Brito Sauvanell  , Greet Cuyvers  , Guy Reggers  , Pieter Samyn  , Dries Vandamme  , Jan Yperman  , Peter Adriaensens  and Robert Carleer

Received: 25 October 2022;  Published: 21 April 2023;  doi: 10.21926/aeer.2302028

The chemical regeneration of exhausted granular activated carbon (GAC) from a water treatment plant to produce dialysis water used in hemodialysis treatments for chronic renal disease patients from a general Hospital of Ciego de Avila province, Cuba, was investigated. Activated carbon (AC) exhausted mainly by inorganics (Ca (Ca-chelates), Mg and Na) was regenerated using hydrochloric acid and acetic acid (one regeneration cycle). Solutions of 5%, 10%, 15% and 20%(v/v) as well as four contact times (2 h, 4 h, 6 h an [...]

by Aleksandra Oledzka  and Lynne Ann Barker

Received: 05 March 2019;  Published: 06 May 2021;  doi: 10.21926/obm.neurobiol.2102093

Brain training apps are becoming increasingly popular for at home use and as an adjunct to more traditional therapies. There is uncertainty about whether the effects of brain training transfer to real-world cognition, or performance on other cognitive assessment tests, or is specific only to the brain training app. Executive functions (EF’s) are higher-order cognitive processes important for activities of everyday living and autonomous goal-directed behaviour [1]. EF’s are associated with frontal brain networks tha [...]

by Tanja Radu  , Vincent Smedley  , Dipti Yadav  , Richard Blanchard  , Sheik Aminur Rahaman  , P. Abdul Salam  and Chettiyappan Visvanathan

Received: 21 September 2022;  Published: 28 November 2022;  doi: 10.21926/jept.2204039

The implementation of community-level de-centralised anaerobic digestion (AD) systems offers a sustainable solution for organic waste management and energy provision, but there is currently a need for low-cost methods of system control and management at this scale. The problem becomes accentuated with increasing deployment, as greater complexities are created by the need to both monitor and control a wider network of smaller, community-scale plants. This paper describes research to design, deploy and test such a sy [...]

by Marina Maier  , Amela Ajanovic  and Reinhard Haas

Received: 23 June 2024;  Published: 06 December 2024;  doi: 10.21926/aeer.2404026

The transport sector accounts for approximately 25% of CO2-emissions in the EU and Austria, primarily due to passenger car transport powered by fossil fuels. Replacing conventional cars with sustainable alternatives is crucial for reducing emissions, improving air quality, and mitigating climate change while decreasing vehicle kilometers driven. This study analyzes policy strategies for Austria’s road passenger transport sector up to 2050 to determine their potential for significant CO2 reduction. Four scenar [...]

by Gemechu Fanta Garuma

Received: 29 March 2022;  Published: 06 June 2022;  doi: 10.21926/aeer.2202022

An increase in global temperature will likely result in more intense and frequent heatwaves that would last longer. Simultaneously, the growth of urban population requires more areas of land incorporated into urbanization, because most people are expected to live in cities, which will increase the intensity and duration of urban heat islands. However, the extent of the link between global warming induced heatwaves and urbanization caused heat islands is barely understood. Understanding the link would give a new inf [...]

by Elaine Beaumont  , Chris Irons  and Sue McAndrew

Received: 25 May 2022;  Published: 26 September 2022;  doi: 10.21926/obm.icm.2203045

Self-guided, smartphone apps may be helpful in reducing symptoms associated with psychological distress and may boost wellbeing, and levels of compassion. To our knowledge this is the first study to examine the impact a 28-day app based on Compassion Focused Therapy and Compassionate Mind Training has on participant’s levels of compassion, wellbeing, and self-criticism. The Self-Compassion App includes exercises, meditations, quotes, a daily wisdom, and audios, all of which aim to help individuals develop com [...]

by Walter Hughes

Received: 12 September 2018;  Published: 06 December 2018;  doi: 10.21926/obm.genet.1804052

My experiences with the identification and development of the anti-Pneumocystis drugs trimethoprim-sulfamethoxazole, dapsone and atovaquone are recounted. Attention is drawn to certain often-overlooked aspects of these drugs, including their concomitant effects against infections other than Pneumocystis, matters of dosing and adverse effects. During the past four decades several million people worldwide received chemoprophylaxis and treatment with these drugs for Pneumocystis jirovecii pneumonia. The population of [...]

by Yoko Moriyama  , Timothy Bolt  , Marilyn Luptak  and Nanako Tamiya

Received: 19 February 2019;  Published: 09 July 2019;  doi: 10.21926/obm.geriatr.1903061

Background: Many informal caregivers providing at-home care to older family members want to continue serving as the primary caregiver if they get sufficient support. A key service enabling continued at-home care is access to unplanned respite care facilities for temporary institutional care on short notice and in emergencies. Methods: This study used city government survey results on service user satisfaction with the Japanese Long-Term Care Insurance (LTCI) system for a mid-sized, Japanese city. From this a range [...]