by Darcy L. Harris

Received: 26 August 2023;  Published: 16 November 2023;  doi: 10.21926/obm.icm.2304052

In the past several decades, new understandings about grief have emerged. In the same time frame, a substantial body of literature has explored the components of compassion and their potential application to various clinical contexts. Compassion evolved from caring motivation associated with the evolutionary challenges of reproduction that involved the necessary care for offspring. Grief also has an evolutionary background that is rooted in core aspects of attachment and the assumptive world construct. Compassion F [...]

by Rosita Borlimi  , Greta Riboli  , Mattia Nese  , Matilde Buattini  , Marella Colombardo  and Gianni Brighetti

Received: 07 November 2021;  Published: 01 April 2022;  doi: 10.21926/obm.icm.2202014

The length of the menstrual cycle (MC) varies among women, with an average regularity between 21 and 40 days. Six temporal frames can be observed within the monthly cycle, based on the fluctuations of the hormone levels. These fluctuations are accompanied by alterations in the central nervous system (CNS) and autonomic nervous system (ANS) and can be quantified using psychophysiological techniques. In this systematic review, we discussed the studies conducted with healthy females that examined aspects associated wi [...]

by Natasha Hui Jin Ng  , Wei Xuan Tan  , Ye Xin Koh  and Adrian Kee Keong Teo

Received: 11 March 2019;  Published: 21 June 2019;  doi: 10.21926/obm.transplant.1902068

The ability to routinely and reproducibly obtain purified human islets has facilitated substantial progress in providing a safe and reliable treatment option for adult patients of type 1 diabetes. The availability of human islets for basic research has also significantly improved the understanding of the biology of human islets, and consequently the pathophysiology of diabetes. Presently, about 70 human islet isolation centers are known to exist around the world, in addition to multiple coordinated human islet dist [...]

by Roland Pässler

Received: 17 June 2021;  Published: 22 November 2021;  doi: 10.21926/rpm.2104042

The well-known classical heat capacity model developed by Debye proposed an approximate description of the temperature-dependence of heat capacities of solids in terms of a characteristic integral, the T-dependent values of which are parameterized by the Debye temperature, ΘD. However, numerous tests of this simple model have shown that within Debye's original supposition of approximately constant, material-specific Debye temperature, it has little chance to be applicable to a larger variety of non-metals, e [...]

by Maurizio Gabrielli  , Veronica Ojetti  , Marcello Candelli  , Luca Santarelli  , Antonio Gasbarrini  and Francesco Franceschi

Received: 18 August 2020;  Published: 09 February 2021;  doi: 10.21926/obm.neurobiol.2101087

Celiac disease (CD) is a common gluten-related enteropathy that presents several extra-intestinal manifestations. Migraine is globally recognized as one of the most diffuse primary headaches. The present paper aims to review the current evidence on the possible association between CD and migraine. Both adults and children having CD exhibit a high prevalence of migraine. However, screening for CD in an unselected population of migraineurs demonstrated contrasting results. Brain imaging may reveal cerebral calcificat [...]

by Andreea L. Seritan

Received: 31 July 2023;  Published: 24 October 2023;  doi: 10.21926/obm.geriatr.2304254

Climate change is a major public health emergency. Natural disasters (earthquakes, floods, hurricanes, tornadoes, tsunamis, landslides, wildfires, and volcanic eruptions) have been increasing in frequency and severity and can cause lasting psychological sequelae. Older adults are highly vulnerable to the physical and mental health impacts of extreme weather and natural disasters. A narrative review was conducted to identify and summarize English-language articles focusing on the impact of climate change on older ad [...]

by Alexander Henn  and Maija-Liisa Mattinen

Received: 08 March 2019;  Published: 26 April 2019;  doi: 10.21926/rpm.1902001

Technical lignins from the biorefinery, pulp, and paper industries are largely underutilized, even though this aromatic and randomly structured biopolymer could be an interesting raw material for advanced applications in addition to bulk daily goods. Recently, colloidal lignin particles (CLPs) have gained much of the research interests due to the attractive multi-functional properties of the biopolymer. Utilization of lignin in nanoparticulate morphology resolves most of the drawbacks when using lignin (heterogenei [...]

by Sima Farpour  , David Smithard  and Hamid reza Farpour

Received: 14 November 2019;  Published: 20 February 2020;  doi: 10.21926/obm.geriatr.2001109

Dysphagia is a term that is used for the difficulty in moving liquid/food from mouth to the stomach. Dysphagia is very common in elders, which makes them susceptible to malnutrition, infection, institutionalization, and death. Consequently, it is categorized as a geriatric syndrome. Therefore, multidisciplinary teams need to work together to determine the correct etiology and implement an appropriate care plan. Oral care is crucial in managing dysphagia and dental hygienists and dentists serve as the key members. I [...]

by Onix Cantres-Fonseca  , Shambhu Aryal  , Christopher King  and Steven D. Nathan

Received: 25 May 2023;  Published: 20 February 2024;  doi: 10.21926/obm.transplant.2401207

Chronic allograft dysfunction (CLAD) is one of the leading causes of death after lung transplantation [1]. CLAD is a progressive and irreversible decline in lung function after transplant, manifested as an obstructive, restrictive, or mixed ventilatory impairment without any identifiable etiology as infection or acute rejection. Multiple risk factors have been associated with this condition. Despite its significant effect on the mortality of transplanted patients, there is still a lack of powerfully effective thera [...]

by Andrew G.L. Douglas  and Diana Baralle

Received: 31 December 2020;  Published: 08 March 2021;  doi: 10.21926/obm.genet.2101125

A large proportion of rare disease patients remain undiagnosed and the vast majority of such conditions remain untreatable whether diagnosed or not. RNA splicing analysis is able to increase the diagnostic rate in rare disease by identifying cryptic splicing mutations and can help in interpreting the pathogenicity of genomic variants. Whilst targeted RT-PCR analysis remains a highly sensitive tool for assessing the splicing effects of known variants, RNA-seq can provide a more comprehensive transcriptome-wide analy [...]