by Elisabetta Barbara Cortesi  , Sonia Baccetti  , Maria Valeria Monechi  , Mariella Di Stefano  , Barbara Cucca  , Tommaso Conti  , Antonella Traversi  , Filippa Terranova  , Roberto Montelatici  , Sylvie Yvonne Barberousse  , Federica Sabatini  , Catia Vuono  , Christian Bini  and Marco Picchi

Received: 26 September 2018;  Published: 28 April 2019;  doi: 10.21926/obm.icm.1902028

Introduction: Pain in musculoskeletal disorders is a common problem that involves high social and individual costs. Systematic reviews and randomized controlled trials show that a number of treatments usually applied in this field are not effective. On the other hand, there is clinical evidence of the effectiveness of physical exercise, acupuncture, and auriculotherapy. Side effects of current medication limit their use. Aim: To evaluate the effectiveness of auriculotherapy on the pain of patients suffering from ch [...]

by Jeremy M. Quintana  , Alexandra L. Stinchcomb  , Jessica H. Kostyo  , Blair M. Robichaud  , Michael A. Plunk  and Robert R. Kane

Received: 08 October 2018;  Published: 28 December 2018;  doi: 10.21926/obm.transplant.1804036

Islet transplantation has proven to be a viable treatment for individuals suffering from both Type 1 Diabetes Mellitus (T1D) and chronic pancreatitis. However, a variety of challenges limit the effectiveness of this procedure by reducing the number of islets that survive the harvesting and transplantation processes. Increasing islet survival would increase the long-term effectiveness of the procedure and allow this technique to be used in more patients. A number of factors have been shown to improve the outcomes of [...]

by Robert J Emanuel

Received: 09 January 2019;  Published: 21 March 2019;  doi: 10.21926/obm.geriatr.1901040

The amount of patients who suffer with dementia is set to rise with an ageing population. As well as living longer, patients will be retaining their natural teeth into their later life and will be less reliant on dentures. From both the current evidence available in the literature, and anecdotally from clinicians experienced in treating patients with dementia, it can be concluded that on balance, patients with dementia appear to be at a greater risk from dental caries (dental decay). However, more research in this [...]

by Jaspreet Kaur  , Khushveer Kaur  , Khushwinder Kaur  , Avtar S. Matharu  and Surinder K. Mehta

Received: 14 December 2022;  Published: 14 April 2023;  doi: 10.21926/aeer.2302027

Continued industrialization, urbanization and ecological destruction have caused significant environmental problems, particularly increased water pollution. Introducing harmful organic and inorganic effluents into watercourses has limited the supply and accessibility of safe and affordable drinking water. There is an urgent need to find green and sustainable abatement solutions for water remediation, many based on nanoparticles. The primary objective of this review is to explore and have a comprehensive discussion [...]

by Manuel Legree  , Jocelyn Sabatier  , Fabrice Mauvy  , Abdel Salam Awad  , Matthieu Faessel  , Frederic Bos  and Jean-Louis Bobet

Received: 04 March 2020;  Published: 28 April 2020;  doi: 10.21926/jept.2002004

This paper focuses on hydrogen production for green mobility applications (other applications are currently under investigation). Firstly, a brief state of the art of hydrogen generation by hydrolysis with magnesium is shown. The hydrolysis performance of Magnesium powder ball–milled along with different additives (graphite and transition metals TM = Ni, Fe, and Al) is taken for comparison. The best performance was observed with Mg–10 wt.% g mixtures (95% of theoretical hydrogen generation yield in about 3 min). An [...]

by Jacques Pédron  and Frédérique Van Gijsegem

Received: 25 July 2019;  Published: 26 November 2019;  doi: 10.21926/obm.genet.1904098

Background: Genus Dickeya comprises aggressive soft rot plant pathogens with wide geographic distribution and host ranges. Ten Dickeya species were characterized. Seven of them (Dickeya chrysanthemi, D. dadantii, D. dianthicola, D. fangzhongdai, D. solani, D. paradisiaca, and D. zeae) group causative agents of maceration-associated diseases that impact a wide variety of crops or ornamentals as well as isolates from fresh water. The other three species (D. aquatica, D. lacustris, D. undicola) were recently isolated [...]

by Chrisann Fahy  and Lisa Hollis-Sawyer

Received: 19 January 2018;  Published: 10 October 2018;  doi: 10.21926/obm.geriatr.1804014

Background: The growing aging population requires care support resources which engage older adults in many different aspects of human functioning and experiences [1]. The purpose of this applied research project was to develop, and pilot test a holistic enrichment program manual used with Institutionalized Residential Care Facilities (IRCF) that encompasses motor skill, social, cognitive and self- enrichment outcomes, and to pilot test the enrichment program manual to be both cost-effective and a time savings to IR [...]

by Andrew G.L. Douglas  and Diana Baralle

Received: 31 December 2020;  Published: 08 March 2021;  doi: 10.21926/obm.genet.2101125

A large proportion of rare disease patients remain undiagnosed and the vast majority of such conditions remain untreatable whether diagnosed or not. RNA splicing analysis is able to increase the diagnostic rate in rare disease by identifying cryptic splicing mutations and can help in interpreting the pathogenicity of genomic variants. Whilst targeted RT-PCR analysis remains a highly sensitive tool for assessing the splicing effects of known variants, RNA-seq can provide a more comprehensive transcriptome-wide analy [...]

by Rachel Mills  , Louisa Jackman  , Mithila Mahesh  and Ian James

Received: 12 December 2018;  Published: 11 February 2019;  doi: 10.21926/obm.geriatr.1901032

Background: Research suggests that the use of lies and deception is prevalent within dementia care settings, despite ongoing debates raised about the ethics of this approach. There has been increasing exploration of when and why deceptive practices should be used, but the lack of clarity as to what constitutes a lie has caused difficulty in ensuring that lies are used ethically. The aim of this study was to widen our understanding of the key dimensions that underpin the use of lies, and further to use this informat [...]

by Olorunjuwon O. Bello  , Rosemary O. Akande  , Temitope K. Bello  , Muibat O. Fashola  , Mathew O. Oni  and Adeleke Osho

Received: 21 July 2024;  Published: 20 January 2025;  doi: 10.21926/obm.icm.2501006

The incidence of antifungal-resistant pathogenic fungi has steadily increased around the globe and calls for an aggressive response. The study aimed to produce and evaluate virgin coconut oil's phytochemical properties and antifungal potentials (VCO). The production of VCO was achieved by hot extraction and natural fermentation methods. Gas Chromatography-Mass Spectrometry (GC-MS) was used to evaluate the active phytochemicals in the VCO. The antifungal activities of VCO against Aspergillus flavus, Aspergillus nige [...]