by Maggi A Budd  and Michelle E Mlinac

Received: 30 January 2025;  Published: 30 May 2025;  doi: 10.21926/obm.geriatr.2502314

Identifying and addressing ethical issues in the care of older adults can be complex and challenging in clinical settings. This article reviews specific ethical principles including autonomy, beneficence, non-maleficence, dignity, and justice, and explores them in the context of interprofessional geriatric care. Situations and related ethical components such as treatment in intensive care units, end-of-life care, dementia care, and aging with advancing technology are included. Case scenarios for each principle or s [...]

by Jeremy M. Quintana  , Alexandra L. Stinchcomb  , Jessica H. Kostyo  , Blair M. Robichaud  , Michael A. Plunk  and Robert R. Kane

Received: 08 October 2018;  Published: 28 December 2018;  doi: 10.21926/obm.transplant.1804036

Islet transplantation has proven to be a viable treatment for individuals suffering from both Type 1 Diabetes Mellitus (T1D) and chronic pancreatitis. However, a variety of challenges limit the effectiveness of this procedure by reducing the number of islets that survive the harvesting and transplantation processes. Increasing islet survival would increase the long-term effectiveness of the procedure and allow this technique to be used in more patients. A number of factors have been shown to improve the outcomes of [...]

by Simonetta Bernardini  , Francesca Bechini  , Giulia Braccesi  , Franco Cracolici  , Rosaria Ferreri  , Roberto Pulcri  and Andrea Serafini

Received: 30 September 2018;  Published: 17 April 2019;  doi: 10.21926/obm.icm.1902024

Since 2011, the Tuscany Regional Authority has been funding the use of Integrated Medicine (IM) in a clinical setting in Pitigliano Hospital, with the aim of testing the true efficacy of complementary and alternative medicine (CAM) in a hospital setting. The clinical setting also comprises the Manciano rehabilitation facility whose services include post-stroke rehabilitation. This study aims to establish if IM helps to improve the rehabilitation performance of stroke patients. The study compared 212 patients divide [...]

by Rachel Mills  , Louisa Jackman  , Mithila Mahesh  and Ian James

Received: 12 December 2018;  Published: 11 February 2019;  doi: 10.21926/obm.geriatr.1901032

Background: Research suggests that the use of lies and deception is prevalent within dementia care settings, despite ongoing debates raised about the ethics of this approach. There has been increasing exploration of when and why deceptive practices should be used, but the lack of clarity as to what constitutes a lie has caused difficulty in ensuring that lies are used ethically. The aim of this study was to widen our understanding of the key dimensions that underpin the use of lies, and further to use this informat [...]

by Darcy L. Harris

Received: 26 August 2023;  Published: 16 November 2023;  doi: 10.21926/obm.icm.2304052

In the past several decades, new understandings about grief have emerged. In the same time frame, a substantial body of literature has explored the components of compassion and their potential application to various clinical contexts. Compassion evolved from caring motivation associated with the evolutionary challenges of reproduction that involved the necessary care for offspring. Grief also has an evolutionary background that is rooted in core aspects of attachment and the assumptive world construct. Compassion F [...]

by Peng Li  , Chi-Yao Chang  and Amsini Sadiki

Received: 02 April 2021;  Published: 28 June 2021;  doi: 10.21926/jept.2102026

A numerical model describing the ballistic behavior of a commercially used initiator is presented in this article. This model was built on the principle of conservation of mass and energy in the multi-phase framework incorporated with multi-loaded conditions. After obtaining the information about the grain size distribution in each composite, a fixing factor was proposed based on the surface area ratio of the composites. Thus, the solid propellant burning process based on distributed grain size was described, and t [...]

by Chrisann Fahy  and Lisa Hollis-Sawyer

Received: 19 January 2018;  Published: 10 October 2018;  doi: 10.21926/obm.geriatr.1804014

Background: The growing aging population requires care support resources which engage older adults in many different aspects of human functioning and experiences [1]. The purpose of this applied research project was to develop, and pilot test a holistic enrichment program manual used with Institutionalized Residential Care Facilities (IRCF) that encompasses motor skill, social, cognitive and self- enrichment outcomes, and to pilot test the enrichment program manual to be both cost-effective and a time savings to IR [...]

by Shefali Mody  , Soham Nadkarni  , Shreyash Vats  , Akshay Kumar  , Sravanthi Nandavaram  and Suresh Keshavamurthy

Received: 09 July 2023;  Published: 23 November 2023;  doi: 10.21926/obm.transplant.2304203

The shortage of donor lungs for transplantation is a major challenge, resulting in longer waitlist times for patients with a higher risk of waitlist mortality. It is crucial to continue promoting awareness about organ donation through legislation, public campaigns, and health care provider education. Only a small number of cadaveric donors meet the ideal criteria for lung donation, leaving many lungs unused. Donor lung utilization can be improved by carefully considering the extended-criteria donors, actively parti [...]

by Andrew G.L. Douglas  and Diana Baralle

Received: 31 December 2020;  Published: 08 March 2021;  doi: 10.21926/obm.genet.2101125

A large proportion of rare disease patients remain undiagnosed and the vast majority of such conditions remain untreatable whether diagnosed or not. RNA splicing analysis is able to increase the diagnostic rate in rare disease by identifying cryptic splicing mutations and can help in interpreting the pathogenicity of genomic variants. Whilst targeted RT-PCR analysis remains a highly sensitive tool for assessing the splicing effects of known variants, RNA-seq can provide a more comprehensive transcriptome-wide analy [...]

by Geeta Pokhrel  , Hongmei Gu  , Douglas J. Gardner  and Shane O'Neill

Received: 07 December 2021;  Published: 09 February 2022;  doi: 10.21926/rpm.2201003

This study is expanding the previous studies that were focused on the material properties and transportation costs of the two alternative feedstocks for manufacturing wood-plastic composites (WPCs): wood flour and pellets. Besides the material properties and cost analysis, life-cycle assessment (LCA) is equally important to assess the environmental impacts of these two alternative wood feedstocks to manufacture WPCs and gain the knowledge of influences from the manufacturing and transportation processes. The main g [...]