by Steve Liebich

Received: 16 March 2020;  Published: 02 July 2020;  doi: 10.21926/obm.genet.2003113

Multicellularity has gained the advantage over the unicellular world by expanding the number of increasingly more complex tissues that achieve advanced and specific functions. This same event gave rise to the most evolved group of organisms, namely mammals. Even though the complexity of multicellular organisms does not necessarily provide them with excellent adaptation modes performed by unicellular and prokaryotic organisms, this complexity per se stands as one of the greatest phenomena in biology. However, there [...]

by Lucy V. Fisher  and Andrew R. Barron

Received: 24 February 2021;  Published: 16 July 2021;  doi: 10.21926/rpm.2103028

One of the largest problems facing the steelmaking industry is the high amount of waste currently produced and the low amount of waste that is currently recycled. This study aims to look at the suitability of 3 different samples of basic oxygen steelmaking (BOS) slag as a construction material, in concert with their carbon capture capacity. Characterization by scanning electron microscopy (SEM), X-ray diffraction (XRD), inductively coupled plasma spectroscopy (ICP), X-ray fluorescence (XRF), CO2 adsorption analysis [...]

by Carlos A. Echeverry-Gonzalez  and Vladimir V. Kouznetsov

Received: 01 December 2020;  Published: 28 April 2021;  doi: 10.21926/rpm.2102015

The design of nanomaterials for application in diverse fields ranging from photovoltaic to fluorescence sensing is a research area of increasing interest. Recently, Quantum Dots (QDs), which are classified as semiconductor quantum dots (SQDs) and Carbon dots (CDs), have become a hot topic of investigation, owing to their extraordinary tunable fluorescence emission properties that render them excellent candidates for sensing metal ions. The detection of metal ions in aqueous solutions with high sensitivity is very i [...]

by Alice Walton  , Mustafa Faruk Usta  , Melissa Wong  and Wayne Hellstrom

Received: 01 August 2021;  Published: 02 November 2021;  doi: 10.21926/obm.icm.2104042

Metabolic syndrome (MetS) is considered a risk factor for erectile dysfunction (ED), and ED is almost three times more prevalent in men with MetS. Vascular pathologies are a significant factor for the development of ED, and many experts suggest endothelial dysfunction (EnD) as a likely explanation for the association between ED and MetS. Studies also show that corporal vascular and trabecular smooth muscle dysfunction leads ultimately to corporal veno-occlusive dysfunction. Different functional system abnormalities [...]

by Heidrun Männle  , Birthe Osorio  and Karsten Münstedt

Received: 09 March 2020;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002024

Palliative care is a steadily growing component of medicine that focuses on treating individuals with life-limiting diseases such as cancer. It aims at improving the quality of life and alleviating cancer-related symptoms, including anxiety, pain, dyspnea, cough, nausea/vomiting, and constipation, which could result in significant physical and mental impairment. Integrative palliative care (IPC), as a subspecialty of palliative care, includes complementary approaches to treat patients holistically in their biopsych [...]

by Niamh Flynn

Received: 18 March 2021;  Published: 02 May 2021;  doi: 10.21926/obm.neurobiol.2102092

Although studies to understand the pathogenesis of migraines are in progress, no theory has adequately explained the etiology and pathophysiology of migraines to date. This has affected the development of treatment strategies for migraineurs. Currently, the pharmacological treatment for migraines provides both acute and prophylactic options to patients based on a biomedical model of pain. However, patients’ adherence to oral migraine preventive medication (OMPM) is poor, and their persistence is even lower when the [...]

by Michael F Knoll  , Carmela A Knoll  , Rita Bottino  , Suzanne Bertera  and Massimo Trucco

Received: 12 January 2021;  Published: 25 March 2021;  doi: 10.21926/obm.transplant.2101140

Clinical islet transplantation was first realized over four decades ago at the University of Minnesota. Autologous islet transplantation is now widely recognized as a treatment to prevent diabetes in patients after pancreas excision and is offered at major transplant centers throughout the United States and the world. Type 1 diabetes represents a much larger demographic in which islet transplantation may benefit patients. Allogeneic islet transplantation can now offer similar outcomes to pancreas transplantation in [...]

by Prabhumallikarjun Patil  and Amanda RB Weber

Received: 18 January 2022;  Published: 22 July 2022;  doi: 10.21926/obm.neurobiol.2203129

Cerebral palsy is defined as “A group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non-progressive disturbances that occurred in the developing fetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cognition, communication, and behavior, by epilepsy, and by secondary musculoskeletal problems [1].” Between 30-40% of people with cerebral palsy also have epilepsy [2,3,4]. Som [...]

by JeongChul HEO  and Sumi HAN

Received: 15 June 2022;  Published: 08 October 2022;  doi: 10.21926/obm.neurobiol.2204141

This study aimed to verify whether self-directed learning readiness (SDLR) level can be significantly predicted by the literacy of learning management system (LLMS), motivation, and feedback interaction (FI) in non–face-to-face educational settings. We performed Pearson’s correlation analysis and multiple regression analysis. A total of 206 online college students responded to this web survey using simple random sampling. Results showed that three variables (LLMS, motivation, and FI) were positively associated with [...]

by Chiara Castellani  , Emanuele Molteni  , Serena Colafrancesco  , Fabrizio Conti  , Roberta Priori  and Rossana Scrivo

Received: 13 August 2020;  Published: 18 November 2020;  doi: 10.21926/obm.geriatr.2004139

Musculoskeletal conditions represent one-third to more than one-half of all non-communicable disease multimorbidities in the elderly, worsening their disability because of pain and limited physical function, often concurring with their mental decline. Musculoskeletal conditions significantly contribute to frailty and global disability, second only to mental health conditions. Furthermore, premature mortality, generally due to an increased risk of developing cardiovascular disease, has been documented in several rhe [...]