The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until Extinction
Abstract
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The Contribution of Dietary Fatty Acids to Prediction of All-Cause Mortality in a Cohort of Middle-Aged Men Followed-Up for 61 Years Until ExtinctionAbstract
To describe the contribution of three classes of dietary fatty acids to all-cause mortality and age at death among middle-aged men followed up for 61 years until extinction. The cohort comprised 1712 men aged 40-59 years at entry examination in 1960, belonging to the Italian Rural Areas of the Seven Countries Study of Cardiovascular Diseases. A dietary survey allowed to estimate dietary fatty acids [saturated (SAFA), mono-unsaturated (MUFA), poly-unsaturated (PUFA) and their ratios (M/S, P/S)] that were fed as poss [...] 1101 4385 |
Acknowledgement to Reviewers of OBM Neurobiology in 2023Abstract
The editors of OBM Neurobiology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2023. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal’s editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers can sign up to the [...] 989 4377 |
An Exploration of the Experiences of Group Compassion Focused Therapy for Hospital Outpatients with Long-Term Mental Health Difficultiesby
Abstract
There is now good evidence for the efficacy of Compassion Focused Therapy (CFT) for a variety of mental health difficulties. To deepen understanding of the processes underpinning CFT’s effectiveness, this service evaluation explored the experiences and reflections of individuals with long-term mental health difficulties who had previously received therapy and attended an 11-week CFT group. Ten clients were invited to the group; one withdrew before the group started because of work and personal commitments and anoth [...] 2387 4332 |
“At My Age, Its Perhaps the End of My Walking or the End of a Lot of My Life”: A Phenomenological Study of the Lived Experiences of a Serious Fall to Independent Older AdultsAbstract
The purpose of this original research was to describe the lived experience and meaning of a serious fall to independently residing older adults. A qualitative phenomenological approach was utilized with a purposive sample of 19, independent, high-level functioning older adult residents of a Continuing Care Retirement Community to describe their most serious fall and its personal meaning. Traced through multiple data sources, interpretive analysis of the language expressed by older adults were integrated to support [...] 955 4320 |
Modeling the Mesoscopic-Scale Spatial Evolution of the Epileptic Pre-Ictal and Ictal PhasesAbstract
The spatial evolution of the epileptiform regime in neural networks can be alternatively described in terms of a statistical approach, dealing with average smooth, differentiable fields rather than discrete neural elements. After a brief review of mathematical methods for modeling epilepsy (the condensed matter vs. the neural mass models) together with their pros and cons, we introduce our continuous-space model for the pre-ictal scalar field and the ictal epileptiform vector flux in the form of the diffusion equat [...] 1068 4311 |
External Validation and Modification of a New Score for Predicting Mortality in Patients with COVID-19 in High Altitude Patients. A Peruvian Studyby
Abstract
This study aims to validate two predictive mortality scores for patients with COVID-19 to support clinical decision-making in those who require hospitalization. The tomographic patterns found can be added to the original scores to increase their predictive power. Retrospective, analytical, observational, and cross-sectional studies were carried out in two phases. 489 medical records of patients with COVID-19 hospitalized at “Daniel A. Carrión” Hospital in Huancayo (located at 3,250 meters above sea level) were revi [...] 768 4301 |
Mechanisms of Action of Ready-to-Use Therapies in Hematologic Malignancies: From Clinical Impact to Future Directionsby
Abstract
Off-the-shelf cellular therapies, utilizing allogeneic T cells derived from healthy donors, represent a promising alternative to autologous chimeric antigen receptor T-cell (CAR-T) therapies for the treatment of hematological malignancies such as leukemias and lymphomas. Unlike autologous approaches, which require the patient’s own cell collection, modification, and expansion, off-the-shelf therapies can be prepared in advance, substantially reducing treatment timelines, decreasing costs, and improving global acces [...] 999 4293 |
Impact of Normalization Methods on Metagenomic Characterization of Amaranthus Cruenthus var. Pribina-Associated Microbiomes Under Cadmium StressAbstract
The study of endophytic and rhizosphere microbiota offers considerable potential for applications in agriculture, biotechnology, and bioremediation, given the phytoremediation capacity of Amaranthus cruentus var. Pribina performed a detailed analysis of the root and rhizosphere microbial communities under cadmium (Cd) stress. Although metagenomics provides powerful tools for microbial community profiling, the reproducibility and interpretability of the results are strongly influenced by the data processing strategi [...] 1253 4278 |
Dependence Levels and Oral Functionality in Older Peopleby
Abstract
It has been suggested that an individual's overall functional capacity gradually declines with age. It has been reported that a decline in oral functionality increases the risk of sarcopenia and frailty, which contributes to the decrease in functional capacity. In Chile, the Preventive Medical Examination for Older Adults (EMPAM) is used to assess the functionality of that population; however, this examination does not include an evaluation of oral functionality. To address this gap, the Preventive Dental Examinati [...] 1149 4272 |
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