by Masahiro Sato  , Issei Saitoh  , Yuki kiyokawa  , Eri Akasaka  , Shingo Nakamura  , Satoshi Watanabe  and Emi Inada

Received: 21 January 2022;  Published: 11 April 2022;  doi: 10.21926/obm.genet.2202151

Adipose tissue is distributed throughout the body as fat depots. The amount of adipose tissue increases with age. In mice, epididymal fat depots in males and gonadal fat depots in females are associated with the reproductive system. Regarding fat depots in females, the adipose tissue under the skin can be easily exposed via surgery when the ovary, oviduct, and uterus are pulled out and exposed. As handling adipose tissue is relatively easy, adipocytes might be good targets for genetic manipulation (including gene d [...]

by Seong Soo Choi  , Byung Seong Bae  , Kyoung Jin Kim  , Myoung JIn Park  , Yong Min Lee  , Hyun Tae Kim  and Soo Bong Choi

Received: 22 December 2020;  Published: 05 February 2021;  doi: 10.21926/rpm.2101004

We fabricated various nanoaperture plasmonic platforms for single-molecule detection. We fabricated nanoapertures like nanopores on a pyramid and nanoslits on an Au flat membrane using a Ga ion focused ion beam drilling technique, followed by irradiating with a high energy electron beam, dependent on the electron beam current density to obtain nanoapertures with a few nanometer sizes (circular nanopore, nanoslit pores). We examined their optical characteristics with varying aperture sizes and sample thicknesses. We [...]

by Divya Taneja  , Madhumita Sadhukhan  , Padmalaya Rath  , Manas R Sarangi  , Renu Mittal  , Akshaya Kumar Prusty  , Deepthi Gilla  , Ashish Shivadikar  , Birendra Rawat  , Ravi Kumar Sadarla  , Gurudev Choubey  , Nidhi Mahajan  , Renu Bala  , Neha Kalra  , Anupam Mukherjee  , Anil Khurana  and Raj K. Manchanda

Received: 12 August 2022;  Published: 21 September 2022;  doi: 10.21926/obm.icm.2203044

Patients with psoriasis commonly opt for homeopathic treatment. However, no study has assessed the response to homeopathic treatment by using standardized disease-specific scales, and the findings are based on clinical assessments only. The objective of this study was to evaluate the response to the individualized homeopathic treatment of psoriasis with respect to changes in disease severity and quality of life based on Psoriasis Area and Severity Index (PASI) and Psoriasis Disability Index (PDI) scales, respective [...]

by Ryan L Dimmock  , Xuyiling Wang  , Yibin Fu  , Alicia J El Haj  and Ying Yang

Received: 09 December 2019;  Published: 28 February 2020;  doi: 10.21926/rpm.2001005

Advancements in surface engineering and material fabrication techniques have enabled the creation and replication of naturally occurring surface topographies or the extrapolation of natural patterns to become achievable targets. Polymers are used extensively in the field of biomedical sciences for containment, handling, and as cell culture substrates. It is well established that several polymers exhibit good biocompatibility for cell culture, with properties that include exhibiting minimal to no cytotoxicity and be [...]

by Fengxia Liang  and Gerhard Litscher

Received: 25 February 2020;  Published: 26 February 2020;  doi: 10.21926/obm.icm.2001009

Traditional Chinese Medicine (TCM) has been used to prevent and alleviate epidemic diseases for hundreds of years. The combination of TCM and Western medicine can effectively reduce fever; alleviate cough, fatigue, diarrhoea and other symptoms of patients with mild COVID-19 (Coronavirus disease-19). For the treatment of moderate and severe syndromes, the integrative approach can reduce lung exudation and inhibit the further development of the disease. However the risk of infection is a limit for example in needle a [...]

by Scarlett Puebla-Barragan  , Britney Lamb  , Serenah Jafelice  and Gregor Reid

Received: 16 June 2021;  Published: 01 November 2021;  doi: 10.21926/obm.icm.2104040

Vaginal care products are widely used by women to relieve discomfort such as pain, itching and malodour, all of which are commonly caused by conditions resulting from microbiota dysbiosis. Previous studies showed that probiotic strains Lacticaseibacillus (formerly Lactobacillus) rhamnosus GR-1 (LGR-1) and Limosilactobacillus (formerly Lactobacillus) reuteri RC-14 (LRC-14), can aid in restoring homeostasis in the vaginal microbiome when taken orally. A topical product containing these strains could be of value for r [...]

by Obumneme Emmanuel Ezeani  , Christopher Igwe Idumah  , Ifeanyi Emmanuel Okoye  and Chioma Joan Ikebudu

Received: 13 January 2025;  Published: 27 May 2025;  doi: 10.21926/rpm.2502009

Nanotechnology has revolutionized the textile industry by introducing innovative finishing techniques that enhance the durability and performance of textile materials and the application of nanoscale/nanoparticles/nanomaterials and processes to improve the properties and performance of textiles. The synergism of textile technology and nanotechnological advancements has propelled a paradigm shift, changed the narrative, and formed novel platforms for textile surface engineering at both atomically affiliated and mole [...]

by Camille Jubert Tomasso  , Anne L. Pham  , Tracy M. Mattox  and Jeffrey J. Urban

Received: 20 April 2020;  Published: 19 May 2020;  doi: 10.21926/jept.2002009

Hydrogen (H2) shows great promise as zero-carbon emission fuel, but there are several challenges to overcome in regards to storage and transportation to make it a more universal energy solution. Gaseous hydrogen requires high pressures and large volume tanks while storage of liquid hydrogen requires cryogenic temperatures; neither option is ideal due to cost and the hazards involved. Storage in the solid state presents an attractive alternative, and can meet the U.S. Department of Energy (DOE) constraints to find m [...]

by Adam Spandorfer  , Katelyn Stuart  , Judy Daboul  , Gavisha Waidyaratne  and Subhankar Chakraborty

Received: 12 December 2024;  Published: 28 April 2025;  doi: 10.21926/obm.geriatr.2502309

Dysphagia in the geriatric population, age 65 or older, is increasingly common and a growing concern among healthcare providers. Not only can it critically impact quality of life, but it can also lead to clinically significant malnutrition, hospitalizations, increased length of stays, and has been shown to impact mortality. A multi-disciplinary approach to assess oral, pharyngeal, and esophageal etiologies is key to guiding targeted management, which can include behavioral modifications, medications, and endoscopic [...]

by Elissavet Feloni  and Evgenia Karandinaki

Received: 08 May 2021;  Published: 17 August 2021;  doi: 10.21926/jept.2103039

The objective of this study is the development and implementation of a geographic information system (GIS)-based methodology to determine suitable sites for wind farms by using multicriteria decision making (MCDM) techniques. Many eligibility criteria are considered in this approach, such as GIS analysis is performed in combination with MCDM techniques, both for the criteria weighting process (using the analytical hierarchical process) and for the standardization/classification of the criteria values into a common [...]