by Brittany Montgomery  , Calvin Mammen  and Matt Golden

Received: 18 October 2024;  Published: 09 May 2025;  doi: 10.21926/obm.geriatr.2502311

Assistive technology (AT) interventions have shown promising results in supporting cognitive, social, and physical activities in persons living with dementia (PLWD) and their caregivers. Despite strong evidence of the effectiveness of AT, PLWD and their caregivers can disengage with the technology after it is used for a time – i.e., the “stickiness challenge”. Diminished use of AT reduces the opportunity for it to have optimal impact. We asked whether the opportunity to engage in cognitive games may enhance continu [...]

by Fatimazahra Smaili  , Khawla Zerrouki  , Fatima Ezzahra Aouni  , Ayad Ghanam  , Maria Rkain  , Abdeladim Babakhouya  and Mariam Tajir

Received: 04 October 2024;  Published: 04 February 2025;  doi: 10.21926/obm.genet.2501283

Dystrophinopathies are genetic muscular disorders with recessive inheritance linked to the X chromosome due to mutations in the dystrophin gene, the DMD gene located in Xp21. The best-known forms are Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD). Our study aims to determine the molecular profile and genotype/phenotype correlations of dystrophinopathies in the eastern region of Morocco. We report patients referred for 4 years (2020-2023) to the Medical Genetics Laboratory of the Mohammed VI U [...]

by Tayseer A. S. Idrees  and Ibtisam E. M. El Zubeir

Received: 06 April 2024;  Published: 27 April 2025;  doi: 10.21926/rpn.2502009

This study was conducted to investigate the effect of sources. locations and seasons (late summer and winter) on the chemical composition of cow milk collected from Khartoum State. The samples were collected randomly in the morning or the evening. Two hundred and seventy milk samples were collected from farms (90 samples), groceries (90 samples) and vendors (90 samples) in Khartoum State during the late summer and winter seasons, 135 samples each. The milk samples were kept in cool cracked ice and transported immed [...]

by Yusuke Kataoka

Received: 25 October 2022;  Published: 06 April 2023;  doi: 10.21926/aeer.2302026

Understanding the urban environment and the health status of residents is necessary for appropriate administrative services and regional management. This study used indicator scores derived from the area statistics of cities in the Tokyo metropolitan area to identify factors that affect health status. Indices were classified into two groups: health-related and non-health-related. The index values of each group served as the observed variables and were statistically standardized. The relationship between the two gro [...]

by Recent Progress in Materials Editorial Office

Received: 11 April 2022;  Published: 14 April 2022;  doi: 10.21926/rpm.2202007

An Interview with Prof. Vincenzo M. Sglavo.

by Andrés R. Latorre-Rodríguez  , Devika Sindu  , Sumeet K. Mittal  and Ashwini Arjuna

Received: 23 February 2024;  Published: 21 June 2024;  doi: 10.21926/obm.transplant.2402219

Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii) assess the association between pepA and isolation of typical gastrointestinal microorganisms from BAL fluid, and iii) explore the accuracy of using pepA concentration as a biomarker of ACR. After IRB approval, we conducted a retrospective observational study analy [...]

by Joseph S. D'Arrigo

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

by Nadia A. Abdelmegeed Abdelwahed  and Muhammad Sufyan Ramish

Received: 12 May 2024;  Published: 19 August 2024;  doi: 10.21926/obm.neurobiol.2403242

In the present era of digitalization, technology plays a prominent role in relaxation and brain development (BD), specifically for university students. The present study explores the impact of technology use and digital characteristics (DC) in developing students' BD. We applied the quantitative methods; the study collected 328 samples from Egypt's different public sector universities through a questionnaire. Using path analysis through analysis of moment structures (AMOS), the results demonstrate a positive effect [...]

by Sabrine Mekni  , Lamia Torjemane  , Malek Khayati  , Dorra Belloumi  , Rimmel Yosra Kanoun  , Insaf Ben Yaiche  , Rihab Ouerghi  , Ines Turki  , Saloua Ladeb  , Tarek Ben Othman  and Nour Ben Abdeljelil

Received: 29 June 2024;  Published: 11 November 2024;  doi: 10.21926/obm.transplant.2404226

Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) remains the only curative treatment for bone marrow failure (BMF) and hematologic complications of Fanconi anemia (FA). The evolution remains affected by the toxicity, the risk of graft failure, and clonal evolution. This study aimed to identify factors affecting outcomes in FA patients after allo-HSCT. We included FA patients who underwent allo-HSCT between January 2006 and December 2021. The conditioning regimen was cyclophosphamide/fludarabine (Cy/Fl [...]

by Vladimir N. Gorchakov  , Kirill M. Nicolaychuk  , Olga V. Gorchakova  , Georgi A. Demchenko  and Bayan A. Nurmakhanova

Received: 09 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.geriatr.2304257

Lymph nodes are prioritized in protecting and ensuring endoecological safety at different periods of life, especially in retirement age. It destabilizes the structure and function of the lymphatic system and organs when aging increases the risk of comorbid conditions. This is a sign of age-related pathology. Improving lymph node function is an essential task in integrating gerontology and lymphology. The solution to this problem is possible with the help of a phytotherapeutic agent, which involves the evaluation of [...]