by Anna Scheyett  , Virginia Brown  and Christopher Weatherly

Received: 24 September 2024;  Published: 16 January 2025;  doi: 10.21926/obm.icm.2501005

In this conceptual paper we apply the construct of time poverty to a novel population, farmers struggling with stress and mental health challenges. Farmers have rates of suicide that can be over three times that of the general population, with depression and anxiety at double general population rates. These are linked to the multiple stressors farmers experience due to the unpredictable nature of their work, such as weather, input costs, commodity prices, and government regulations. In addition, there are multiple [...]

by Francesco Peracchi  , Giovanna Travi  , Marco Merli  , Roberto Rossotti  , Fulvio Crippa  and Massimo Puoti

Received: 14 June 2023;  Published: 01 December 2023;  doi: 10.21926/obm.transplant.2304204

SARS-CoV-2 infection has significantly impacted solid organ transplant (SOT) recipients, who are at high risk of disease and worse outcomes. Moreover, therapeutic management in this population is not precise yet. Our study aimed to evaluate the overall survival of SOT recipients and predictive factors for mortality. We also aimed to assess the impact of antiviral treatments and immunosuppressant changes on overall mortality and to evaluate the length of hospital stay of SOT compared to the general population. This [...]

by Benjamin Drukarch  and Micha M.M. Wilhelmus

Received: 09 October 2024;  Published: 13 February 2025;  doi: 10.21926/obm.neurobiol.2501269

According to mainstream neuroscience, the action potential (AP) is a purely dissipative electrical phenomenon that should be modeled as such. However, also (essentially) reversible mechanical, thermal, and optical changes in the neuron have been reported to accompany the movement of the AP along the axonal surface. These are not accounted for in the prevailing (bio)-electric theory of neuronal excitability, originally introduced by Hodgkin and Huxley (HH) and mathematically formulated in their famous HH model of th [...]

by Andrés R. Latorre-Rodríguez  , Devika Sindu  , Sumeet K. Mittal  and Ashwini Arjuna

Received: 23 February 2024;  Published: 21 June 2024;  doi: 10.21926/obm.transplant.2402219

Activated pepsin (pepA) in bronchoalveolar lavage (BAL) fluid may be a biomarker of gastric aspiration. We sought to i) evaluate the association of pepA in BAL fluid with acute cellular rejection (ACR) in a cohort of lung transplant recipients (LTRs), ii) assess the association between pepA and isolation of typical gastrointestinal microorganisms from BAL fluid, and iii) explore the accuracy of using pepA concentration as a biomarker of ACR. After IRB approval, we conducted a retrospective observational study analy [...]

by Yasuhiro Kotera  , Noelia L. Martínez-Rives  , Muhammad Aledeh  , Habib Adam  , Julie Beaumont  , Rory Colman  , Jessica Eve Jackson  , Christian Veasey  , Lucie-May King  , Tracey Harrington  , Elaina Taylor  , Ann-Marie Edwards  , Gabby A. A. Rothwell-Blake  , Adewale Allen Sokan-Adeaga  , Gillian H.T. Liu  , Kenneth Curley  , Matthew Cotterill  , Malik Dimbei Halidu  , Juliet Wilkes  , Aiesha Carew Tofani  , Samantha Greaves  , Rob Hughes  , Annabel Rushforth  , Ann Kirkman  , Michelle Brooks-Ucheaga  and Kristian Barnes

Received: 14 February 2024;  Published: 22 August 2024;  doi: 10.21926/obm.icm.2403048

This short report presents an international research group, Research Ensemble for Advancement in Cross-cultural Healthcare (REACH). REACH is an independent research group, and no one is paid to do research for REACH. All members participate because they are intrinsically motivated to pursue cross-cultural healthcare. REACH consists of 28 healthcare workers and educators from 13 countries, researching about cross-cultural issues in healthcare (18 publications on average per year as of February 2024). REACH is multi- [...]

by Carolina Ramírez  , Elizabeth González  and Fernando Tomasina

Received: 23 September 2024;  Published: 20 May 2025;  doi: 10.21926/aeer.2502023

Healthcare Waste (HCW) management is a pressing challenge in Latin America, where insufficient regulatory enforcement, poor segregation practices, and the lack of accurate generation data hinder sustainable waste management. This study presents a methodological proposal for the internal management of HCWs in Healthcare Centers (HCCs) in Uruguay, based on Decree 586/009 and developed through a situational diagnosis conducted at the Hospital de Clínicas "Dr. Manuel Quintela." The diagnosis involved the qualitative an [...]

by Vsevolod Konstantinov  , Pavel Ustin  and Leonid Popov

Received: 18 July 2023;  Published: 01 November 2023;  doi: 10.21926/obm.icm.2304049

The negative psychological consequences of the COVID-19 pandemic and the forced isolation of a large proportion of people worldwide have demonstrated the need to develop ways and technologies to reduce the effects of sudden threats of this type. The basis of any practical work to minimize the negative psychological consequences of the COVID-19 pandemic associated with substance use is the monitoring and diagnosis of the psychological resources of the individual. The article aims to show the possibilities of predict [...]

by Nadia A. Abdelmegeed Abdelwahed  and Muhammad Sufyan Ramish

Received: 27 October 2024;  Published: 14 February 2025;  doi: 10.21926/obm.neurobiol.2501270

This study examines the effect of e-learning crack-up perception (ECUP) and fear of academic year loss (FAYL) on psychological distress (PD). The study also explores the impact of PD on students' academic performance (AP). It uses a quantitative method based on data collected from Egyptian medical university students using convenience sampling. The study utilized 313 cases to get the final results. Using path analysis through analysis of moment structures (AMOS) software, the study confirmed a positive effect o [...]

by Mohammad-Reza Ghasemi  , Maryam Mirahmadi  , Hadi Bayat  , Mohammad Miryounesi  , Reza Mirfakhraie  , Shadab Salehpour  , Raheleh Tangestani  , Faezeh Sherafat  , Hasan Roudgari  and Milad Gholami

Received: 16 January 2025;  Published: 21 May 2025;  doi: 10.21926/obm.genet.2502294

Kabuki Syndrome (KS) is a rare, multisystem congenital disorder with five foremost clinical manifestations encompassing dysmorphic facial characteristics, postnatal growth constraint, craniofacial/skeletal anomalies, mild to moderate intellectual disability, and dermatoglyphic abnormalities. We analyzed two unrelated Iranian patients suspected of having KS using whole-exome sequencing. An in silico analysis was performed to evaluate the potential effects of the discovered variants on the structure and function of t [...]

by Varrassi Giustino

Received: 01 February 2024;  Published: 02 February 2024;  doi: 10.21926/obm.neurobiol.2401210

Neurobiology is an expansive field of studies encompassing the nervous system's anatomical and physiological aspects [1]. This complex framework's deep study and understanding have facilitated a more intricate comprehension of the interconnections among various nervous system components implicated in pain perception, transmission, modulation, and adaptation.