by Joseph S. D'Arrigo

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

by Ibram Ganesh

Received: 31 July 2025;  Published: 17 September 2025;  doi: 10.21926/rpse.2503013

The United Nations Organization (UNO) in the year 2015 formulated seventeen sustainable development goals (UNO’s 17 SDGs) to be achieved by the end of the year 2030. The so far achieved progress indicates that none of these UNO’s 17 SDGs can be achieved before the deadline. In fact, all these goals can be achieved by developing suitable technologies to fully capture and utilize all the renewable energy resources available on earth to meet all the energy needs of society without any backup from fossil fu [...]

by Alastair C. Gray  , Parker Pracjek  , Christine D. Luketic  and Denise Straiges

Received: 03 September 2024;  Published: 09 December 2024;  doi: 10.21926/obm.icm.2404069

Research into the uptake profile and usage of Homeopathy has hitherto tended to be buried amongst complementary medicine research. Despite high levels of uptake of homeopathy, and robust numbers of over-the-counter sales of homeopathic products the current evidence evaluating the uptake of homeopathy remains limited on several fronts. The aim of this study is to explore the basic demographic features and characteristics of users of homeopathy services. The setting is a student teaching tele-health facility based in [...]

by Yohanes Ridora  , Niken Trisnowati  and Retno Danarti

Received: 05 February 2024;  Published: 19 April 2024;  doi: 10.21926/obm.genet.2402229

Xeroderma pigmentosum (XP) is a rare genodermatosis characterized by increased sensitivity to ultraviolet radiation, leading to severe skin manifestations and a higher risk of early-onset malignancies. Previous studies from temperate climate countries with sound economic levels showed adequate photoprotection compliance among pediatric XP patients. However, no studies have assessed photoprotection compliance among children with XP living in tropical and low-economic settings. This article reports a low photoprotect [...]

by Olubunmi Yemisi Fashoto  , Maureen Nokuthula Sibiya  and Olanrewaju Oladimeji

Received: 09 July 2024;  Published: 08 November 2024;  doi: 10.21926/obm.neurobiol.2404253

The availability and utilization of digital technologies can leverage the challenges of the sharp-depleting workforce due to the consistent migration of healthcare professionals (HCPs), the alarming ratio of the number of patients to HCPs, discretional use of digital technologies among HCPs in providing effective therapeutic interventions and mental healthcare services. This study aimed to develop an operational model that integrates digital technologies in mental healthcare service delivery for public facilities i [...]

by Irina V. Tarasova  and Olga A. Trubnikova

Received: 02 November 2023;  Published: 19 March 2024;  doi: 10.21926/obm.neurobiol.2401215

Postoperative cognitive dysfunction (POCD) has been observed as a complication after cardiac surgery consistently. The ineffectiveness of current treatments for POCD is causing a search for non-invasive alternatives. The present review aims to consolidate the current understanding of how VR methods effectively facilitate the recovery of cognitive functioning in cardiac surgery patients. To obtain information about the effects of VR technology on cognitive functions, we investigated the PubMed, Scopus, and Web of Sc [...]

by Dorcas N. Magai  and Hans M. Koot

Received: 29 May 2024;  Published: 29 November 2024;  doi: 10.21926/obm.icm.2404068

This cross-sectional study addressed the association between parental and family characteristics as risk factors for emotional and behavioral problems (EBP) and quality of life (QoL) and the potential moderation of these associations by adolescents' characteristics. A total of 533 households from Central Kenya with adolescents between 12 to 18 years (median age 15 years) and their mothers (or female caregivers) were included in this study. Adolescents and their mothers completed questionnaires on parent and family [...]

by Amale Laouar

Received: 22 July 2018;  Published: 09 September 2018;  doi: 10.21926/obm.hg.1803010

Gut microbes and pathophysiology of sepsis: Spillage of gut microbial products, rather than systemic dissemination of gut microbes, is the potential initiator of septic morbidity

by Jacqueline B. Sperling  , Abigail M. Stark  and Julianne G. Wilner

Received: 27 January 2025;  Published: 26 June 2025;  doi: 10.21926/obm.icm.2502028

School avoidance is associated with a range of negative outcomes and has been increasing in youth in the past several decades. This study examined the efficacy of an intensive outpatient CBT program, for youth (N = 137, ages 8-19) with anxiety disorders or obsessive-compulsive disorder (OCD) and compared both baseline symptoms and outcomes for youth with school avoidance compared to those without. At admission, results indicated that parents of children with school avoidance reported higher levels of family accommo [...]

by Rolf Teschke  and Axel Eickhoff

Received: 08 January 2025;  Published: 14 February 2025;  doi: 10.21926/obm.transplant.2501234

Liver transplantation (LT) can be the only option for patients with acute liver failure (ALF) where medical approaches are ineffective. Causes of ALF are multiple and commonly easily detectable, but uncertainty remained on the role of drug-induced liver injury (DILI) within the published ALF cohorts. Therefore, an analysis was undertaken to clarify which drugs may have caused the DILI and how the diagnosis of the liver injury was established. Using the PubMed database and Google Science, the search term of acute li [...]