Novel FLNC Gene Variant Associated with Hypertrophic Cardiomyopathy
Abstract
966 5474
Novel FLNC Gene Variant Associated with Hypertrophic Cardiomyopathyby
Abstract
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy, affecting approximately 1 in 500 people. It is the most common genetic cardiomyopathy inherited as a Mendelian trait in approximately 50% of patients, mainly due to pathogenic variants in genes encoding sarcomeric proteins. Mutations in the sarcomeric protein filamin C (FLNC) gene, with a cytogenetic localization on 7q32.1, have been linked to hypertrophic cardiomyopathy, as they have been determined to increase the risk of ventricular a [...] 966 5474 |
How to Keep Doing What You Like Doing: A Qualitative Study of Active Older Adults’ Insights on the Facilitators and Barriers to Maintenance of Physical Activity (From the MOVEAGE-Act Project)by
Abstract
While the facilitators/barriers for the initiation of physical activity (PA) are well documented, there is less known about these facilitators/barriers for maintenance of PA in the older population in general and not following an intervention. This study aimed to explore older adults’ perspectives on the facilitators/barriers to maintaining PA. The study used descriptive qualitative design, with three focus groups, one in Ireland and two in France. Participants were community-dwelling older adults (≥60 years) 66% w [...] 807 5469 |
LFO Damping Enhancement in Multimachine Network Using African Vulture Optimization AlgorithmAbstract
The prolonged presence of low-frequency oscillation (LFO) in power system networks (PSN) poses a significant threat to their stability. Hence, engineers and researchers have continuously developed effective strategies to mitigate the issue and enhance the stability of the PSN. This article proposes a new approach using the African Vultures Optimization Algorithm (AVOA) to design robust Power System Stabilizers (PSS) and enhance the LFO damping in multi-machine networks. The damping ratio-based objective function mi [...] 946 5466 |
Astrocyte-Neuron Interactions in the Neuroinflammatory Cascade of Traumatic Brain InjuryAbstract
Traumatic brain injury (TBI) is a significant public health concern, leading to substantial morbidity and mortality. While the primary injury is mechanical, the subsequent neuroinflammatory cascade plays a critical role in secondary injury and long-term neurological deficits. Astrocytes, the most abundant glial cells in the brain, play a key role in this cascade, interacting with neurons in a complex interplay that can both protect and exacerbate neuronal damage. This paper aims to provide a comprehensive overview [...] 1035 5465 |
Acknowlegement to Reviewers of Journal of Energy and Power Technology in 2020Abstract
The editors of Journal of Energy and Power Technology would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2020. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a cer [...] 1078 5461 |
Acute Liver Failure Due to Assumed Drug Induced Liver Injury but Lack of Any Validated Causality Algorithm: Evidence by 36 Cohort Reports with 21,709 Casesby
Abstract
Liver transplantation (LT) can be the only option for patients with acute liver failure (ALF) where medical approaches are ineffective. Causes of ALF are multiple and commonly easily detectable, but uncertainty remained on the role of drug-induced liver injury (DILI) within the published ALF cohorts. Therefore, an analysis was undertaken to clarify which drugs may have caused the DILI and how the diagnosis of the liver injury was established. Using the PubMed database and Google Science, the search term of acute li [...] 972 5451 |
The Impact of Therapeutic Viniyoga on State ChangeAbstract
While many studies have discussed the effectiveness of interventions using different yoga techniques and teachings with various populations, there has been less research on the effectiveness of yoga therapy. Viniyoga therapists utilize the principles of Viniyoga, a type of yoga developed by Krishnamacharya, to provide therapeutic yogic interventions to individual clients in order to improve functioning and relieve suffering. This qualitative study conducted interviews with fourteen Viniyoga trained yoga therapists [...] 671 5446 |
Importance of SLAPE Solar Panels, Electrochemical CO2 Reduction, Alkaline Electrolyzers and Alkaline Fuel Cells Development to Achieve United Nations Sustainable Development Goalsby
Abstract
The United Nations Organization (UNO) in the year 2015 formulated seventeen sustainable development goals (UNO’s 17 SDGs) to be achieved by the end of the year 2030. The so far achieved progress indicates that none of these UNO’s 17 SDGs can be achieved before the deadline. In fact, all these goals can be achieved by developing suitable technologies to fully capture and utilize all the renewable energy resources available on earth to meet all the energy needs of society without any backup from fossil fu [...] 830 5445 |
Immune-Suppression Modulation in Solid Organ Transplant Recipients Admitted for COVID-19by
Abstract
SARS-CoV-2 infection has significantly impacted solid organ transplant (SOT) recipients, who are at high risk of disease and worse outcomes. Moreover, therapeutic management in this population is not precise yet. Our study aimed to evaluate the overall survival of SOT recipients and predictive factors for mortality. We also aimed to assess the impact of antiviral treatments and immunosuppressant changes on overall mortality and to evaluate the length of hospital stay of SOT compared to the general population. This [...] 947 5433 |
Knowledge and Attitudes Towards Use of Complementary and Integrative Health Therapies for Veterans with Opioid Use Disorder in the Veterans Health Administrationby
Abstract
The Veterans Health Administration (VA) offers complementary and integrative health (CIH) therapies to Veterans with chronic pain and opioid use disorder (OUD). While CIH therapies have known benefits for chronic pain, less research exists on its use for patients with OUD. In this qualitative study, we aimed to assess provider and patient perceptions of CIH therapies for Veterans with OUD. We interviewed 45 providers involved in OUD care and 17 Veterans with OUD from five VA medical centers as part of a larger mixe [...] 995 5409 |
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