Table of Content

Open Access Review

Potential Use of Human Mesenchymal Stem Cells (hMSCs) in Pancreatic Damage/Cancer

Received: 13 March 2024;  Published: 17 July 2024;  doi: 10.21926/obm.genet.2403252

Abstract

Pancreatic damage and pancreatic cancer pose significant challenges due to their complex pathogenesis, limited treatment options, and poor prognosis. In recent years, the potential use of human Mesenchymal Stem Cells (hMSCs) has been explored to address these complex pancreatic conditions and develop novel therapeutics. hMSCs, known for their regenerative and immunomodulatory properties, offer a novel therapeutic avenue for repairing damaged tissues and possibly inhibiting cancer progression. This communication dis [...]

715 5554

Open Access Original Research

Unveiling Genetic Variation in Garlic Genotypes in Response to Rust Disease Using RAPD Markers

Received: 23 January 2024;  Published: 28 April 2024;  doi: 10.21926/obm.genet.2402231

Abstract

Garlic (Allium sativum), cultivated worldwide for its medicinal and nutritional value, faces challenges due to diseases caused by various pathogens. In this study, eleven garlic genotypes from Iran and one from China were selected and sown under natural infection rendered by the rust fungus (Puccinia alli) over two consecutive years. Subsequently, disease distribution and severity, percentage of infection and susceptibility of different garlic genotypes to rust disease were investigated. The results showed that gen [...]

1003 5552

Open Access Original Research

Influence of Thermal Environment Conditions on Mechanical Properties of MEX Printed 17-4 PH Stainless Steel

Received: 18 February 2024;  Published: 22 August 2024;  doi: 10.21926/rpm.2403020

Abstract

This study investigates the influence of thermal environmental conditions during printing and their effects on the mechanical properties of material extrusion (MEX) 3D-printed 17-4 PH stainless steel. Various ambient temperatures and cooling behaviors were used during the printing process of the tensile specimens. Following DIN EN ISO 50125 and DIN EN ISO 6892, the study analyzes tensile strength, elongation and yield strength. The results demonstrate that the thermal environmental conditions affect both tensile an [...]

731 5549

Open Access Original Research

Investigating Cytogenetic Profiles in Couples Experiencing Recurrent Implantation Failure Post in vitro Fertilization

Received: 22 November 2023;  Published: 17 January 2024;  doi: 10.21926/obm.genet.2401211

Abstract

This study evaluates how chromosomal factors affect assisted reproduction techniques (ART) challenges among infertile couples, impacting their chances of conception. Chromosomal abnormalities, a leading cause of pregnancy failure and miscarriages, were investigated in a four-year retrospective study involving 100 patients with a history of infertility and unsuccessful IVF treatment. Among these cases, nine (9%) displayed aberrant chromosomal patterns, including balanced translocations (5%), sex chromosome deletions [...]

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Open Access Original Research

Creating through COVID-19 - An Art-Based Autoethnographic Account

Received: 09 November 2023;  Published: 29 November 2023;  doi: 10.21926/obm.icm.2304057

Abstract

The experience of painting during the COVID-19 period initiated this art-based autoethnographic account. The pandemic affected various fields of life; the discussion is thus pursued from a few interrelated points of view: of an individual coping with the COVID-19 crisis on a personal level, of a painter, of an art therapist, of an art therapy lecturer and supervisor, and an artist involved in community interventions. Artmaking and viewing artworks can enhance communication with the beholder and encourage others to [...]

832 5531

Open Access Original Research

The Psychometric Properties of the COVID Stress Scales in Korean University Students

Received: 13 April 2023;  Published: 07 August 2023;  doi: 10.21926/obm.neurobiol.2303177

Abstract

The COVID-19 pandemic and its associated disruptions have significantly impacted university students’ lives worldwide. The COVID Stress Scale (CSS) is a 36-item self-reporting instrument designed to measure stress caused by the COVID-19 pandemic. This study purposed to examine the psychometric properties of the Korean version of the CSS for use with Korean university students. The study sample comprised 402 undergraduate students enrolled in a four-year private university in central South Korea. This cross-sectiona [...]

749 5526

Open Access Original Research

Assessment of the Main Elements for a Healthcare Waste Management System Using Analytical Hierarchical Process

Received: 16 October 2024;  Published: 10 April 2025;  doi: 10.21926/aeer.2502018

Abstract

When addressing Healthcare Waste Management (HCWM), numerous factors play a crucial role in ensuring its safety and environmentally responsible handling within institutional processes. Recognizing this imperative, this study employed the Analytical Hierarchical Process (AHP) methodology to establish a comprehensive assessment of 10 primary criteria and 66 sub-criteria concerning the governance and operational aspects of Healthcare Waste Management. This evaluation was based on the insights of 14 specialists in the [...]

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Open Access Short Review

Pathophysiological Linkage between Aging and Cognitive Decline: Implications for Dementia Treatment

Received: 26 June 2022;  Published: 19 December 2022;  doi: 10.21926/obm.icm.2204054

Abstract

The cardiovascular risk factors for dementia trigger widespread inflammation and oxidative stress. These two interacting processes lead to neurodegeneration, gradual cognitive/memory decline, and eventually (late-onset) dementia. In addition, there is supporting evidence pointing to elevated pulse pressure as a clear risk factor for cognitive decline. Accordingly, an effective therapeutic strategy to delay dementia could be based upon nanotargeting bioactive molecules, using lipid nanocarriers, toward cell-surface [...]

888 5524

Open Access Original Research

Taste Impairment and Compliance Improvement of Branched-Chain Amino Acids in Patients with Liver Cirrhosis

Received: 25 September 2018;  Published: 26 December 2018;  doi: 10.21926/obm.hg.1804011

Abstract

Background: Branched-chain amino acids (BCAA) are nutrients with a bitter taste, which causes low compliance in patients who need BCAA supplementation. Moreover, chronic liver disease is frequently complicated by taste impairment. The present study was designed to improve patient noncompliance regarding nutrients in liver disease. Methods: A taste questionnaire was administered to healthy controls, chronic hepatitis patients, and cirrhotic patients. Eleven different flavored powders that can be added to BCAA nutri [...]

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Open Access Short Report

The Heavy Burden of Judgement: Cultivating Compassion with People Accessing Healthcare Services for Support with Weight Management

Received: 16 October 2023;  Published: 20 March 2024;  doi: 10.21926/obm.icm.2401020

Abstract

Compassion focused therapy concepts and techniques are explored in the context of weight management efforts within community, specialist and surgical settings. Living at higher weights within a culture that over-values life at low weights can induce feelings of shame, self-loathing and hypercriticism. This article examines points at which individuals engaging in weight management may experience heightened distress and describes some of the ways that the model has been applied with this population. An outline of the [...]

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