by Michal Kawka  , Tamara MH Gall  and Long R Jiao

Received: 25 February 2019;  Published: 05 June 2019;  doi: 10.21926/obm.hg.1902022

Background: Severe necrotising pancreatitis (SNP) is characterised by high mortality, severe complications and bad prognosis despite progress in understanding of aetiology and progression of the disease. Traditionally, necrotic changes were removed by open necrosectomy but the paradigm has shifted towards more conservative management and minimally-invasive surgical procedures. However, there is still no consensus on the best management pathway. Minimally-invasive procedures percutaneous drainage, endoscopic transl [...]

by James D Adams

Received: 01 August 2022;  Published: 04 August 2022;  doi: 10.21926/obm.icm.2203032

Oral pain medicines are routinely used to treat pain and chronic pain. Recent evidence shows that many of these medicines actually increase chronic pain when used over several weeks. Patients should be encouraged to find alternative pain treatments and avoid oral medicines for pain.

by Saba Tanveer  , Ali Saad R. Alsubaie  , Rezzan Khan  , Hajra Ahmed  , Mahpara Safdar  , Zainab Bibi  , Sadaf Yousaf  , Bismillah Sehar  , Iftikhar Alam  , Aiman Hadayat  and Falak Zeb

Received: 31 May 2023;  Published: 15 November 2023;  doi: 10.21926/obm.icm.2304051

Nutrition counseling may assist liver transplant patients in controlling weight gain, addressing micronutrient deficiencies, and maintaining metabolic status. This study aimed to determine the effect of nutritional counseling on nutritional status, liver profile, and serum electrolytes of liver transplant patients. In this case-control study, 100 patients were recruited from Shifa International Hospital, Islamabad, who were potential liver transplant candidates. They were divided into two groups: a case group, who [...]

by Abhideep Chaudhary  , Anish Gupta  , Imtiakum Jamir  , Niteen Kumar  and Gaurav Sood

Received: 23 October 2023;  Published: 01 April 2024;  doi: 10.21926/obm.transplant.2402210

With the progressive rise in rates of liver transplantation, stagnant donor pool, and social factors, living donor liver transplantation (LDLT) forms the majority of liver transplantations performed in Asian countries. As the global prevalence of metabolic-associated fatty liver disease (MAFLD) is increasing, around 17-25% of all the prospective donors turn out to be steatotic at the time of evaluation and, as such, rejected for donor hepatectomy, thereby considerably reducing the living donor pool. Steatotic graft [...]

by Pamela Fox  , Gerald H. Burgess  and Chris Irons

Received: 18 February 2023;  Published: 05 January 2024;  doi: 10.21926/obm.icm.2401004

The aim of this study was to examine the relationships between self-compassion and possible predictors of depressed mood in parents of people with eating disorders. A questionnaire design was conducted cross‐sectionally in a sample of 112 parents of people with eating disorders. Participants completed measures of depressed mood, experiences of entrapment, shame, guilt, self-criticism and self-compassion. Regression analyses showed entrapment and self-criticism to be mediators between the relationship of shame and d [...]

by Richard J. Bloomer  , Marie van der Merwe  , Melissa J. Puppa  and Matthew Butawan

Received: 21 December 2022;  Published: 22 August 2023;  doi: 10.21926/rpn.2303014

Time-restricted feeding (TRF) has increased in popularity among various groups, including fitness enthusiasts. The ideal timing of TRF in relation to daily exercise is unknown. Most fitness enthusiasts consume meals immediately or soon after exercise to improve body composition (e.g., lean mass). We compared two different TRF approaches, as well as an ad libitum control diet, with regards to body mass and body composition in C57BL/6 mice. Young, healthy, male mice exercised five days per week and were assigned to c [...]

by Ines Testoni  , Anna Sapino  , Erika Iacona  , Alessia Montagner  , Luca di Montegnacco  , Laura Liberale  , Alain Borczuk  and Fiorella Calabrese

Received: 14 July 2022;  Published: 14 December 2022;  doi: 10.21926/obm.neurobiol.2204148

During the first wave of the COVID-19 pandemic, pathologists had to follow new protocols in their work environment around the world to limit or prevent the possibility of transmission of the infection during the autopsy of infected corpses. By using a qualitative research design, in this study, we investigated the emotions, experiences, and opinions of pathologists concerning changes in clinical practices. We specifically investigated their perspective on death. Our results encompassed five thematic areas, which in [...]

by OBM Genetics Editorial Office

Received: 05 January 2022;  Published: 06 January 2022;  doi: 10.21926/obm.genet.2201144

The editors of OBM Genetics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2021. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers receive a voucher entitling them to a discount on their next LIDSEN publication and can download a certificate of recognition direct [...]

by Mohsen Akbaribazm

Received: 27 September 2023;  Published: 31 January 2024;  doi: 10.21926/obm.genet.2401212

The escalating prevalence of vision loss due to eye diseases has instigated a quest for innovative therapies, given that conventional approaches often fall short in repairing and regenerating damaged eye tissues, particularly the retina. Stem cell-based interventions have emerged as a promising avenue, with numerous studies in animal models and human trials exploring their potential to enhance visual acuity. Beyond addressing conditions like age-related macular degeneration (AMD) and diabetic retinopathy (DR), stem [...]

by OBM Genetics Editorial Office

Received: 13 December 2022;  Published: 14 December 2022;  doi: 10.21926/obm.genet.2204174

An Interview with Dr. Masahiro Sato