by Michael D. Owens  and Megan Halliday

Received: 24 December 2020;  Published: 30 August 2021;  doi: 10.21926/obm.icm.2103025

The coronavirus (COVID-19) pandemic continues to bring challenges in identification and management of which the “happy hypoxic” or silent hypoxia presentation has been found to present its own unique challenge. A 67-year-old African American COVID-19 positive female presents to the emergency department (ED) with a chief complaint of decreased oral intake and responsiveness, oriented and stable, with oxygen saturations found to drop as low as 47%. The patient was successfully managed with supplemental oxygen and det [...]

by Michael Frass

Received: 13 November 2019;  Published: 14 November 2019;  doi: 10.21926/obm.icm.1904063

Highlights of Application of Homeopathy in Oncology Patients: An Interview with Prof. Michael Frass

by Oreste Piccolo  , Elisabetta Parodi  and Antonella Petri

Received: 14 September 2022;  Published: 17 November 2022;  doi: 10.21926/cr.2204041

In this study, a PoC (Proof of Concept) of a possible biomass valorization of flax and camelina oilseed press cakes was presented. Biocatalyzed hydrolysis of residual oils and proteins extracted from these wastes was studied. The biotransformation of oils was performed using commercial immobilized lipases, including Amano PS, Amano AK, and Candida Antarctica Lipase B (CALB). Acylglycerols were partially or fully hydrolyzed using Amano PS and AK. Triglycerides were not hydrolyzed by CALB, which behaved differently. [...]

by Roberto Anaya-Prado  , Ana P. Cárdenas-Fregoso  , Ana M. Reyes-Perez  , Danielle M. Ortiz-Hernandez  , Montserrat Quijano-Ortiz  , Monica V. Delgado-Martinez  , Ana S. Pelayo-Romo  , Roberto Anaya-Fernández  , Michelle M. Anaya-Fernández  , Consuelo C. Azcona-Ramirez  , Ivan F. Garcia-Ramirez  , Miguel A. Guerrero-Palomera  , Daniel Gonzalez-Martinez  , Citlalli S. Guerrero-Palomera  , Karina Paredes-Paredes  and Claudia Garcia-Perez

Received: 23 February 2024;  Published: 16 July 2024;  doi: 10.21926/obm.neurobiol.2403232

The human gastrointestinal (GI) tract harbors many microorganisms, including viruses, protozoa, archaea, fungi, and bacteria. Altogether, these microbes constitute what we know as the gut microbiome (GM). These commensal communities have important implications for human health. They influence physiological processes through different mechanisms, including synthesizing neurotransmitters, regulating enzymatic pathways, and releasing molecules responsible for different signal pathways. The interaction between GM and b [...]

by Mojtaba Ehsanifar  , Akram Gholami  and Alireza Esmaeili

Received: 27 October 2024;  Published: 18 April 2025;  doi: 10.21926/obm.neurobiol.2502285

There is growing scientific concern regarding how endocrine-disrupting chemicals (EDCs) impact central nervous system (CNS) disorders. Both anecdotal and preclinical studies suggest a link between EDC exposure and major depressive disorder (MDD), potentially leading to neurodegenerative outcomes. EDCs primarily exhibit their biological effects by interacting with hormone receptors. Nonetheless, there is scientific evidence pointing to dysfunction in the hypothalamic-pituitary-gonadal-adrenal axis, which is linked t [...]

by Ginevra G Adamo  , Sergio D'Angelo  , Angeli Christy Yu  , Marco Pellegrini  , Federico Bernabei  , Vincenzo Scorcia  and Giuseppe Giannaccare

Received: 17 June 2022;  Published: 02 August 2022;  doi: 10.21926/obm.transplant.2203164

Graft-versus-host disease (GVHD) is a serious complication that may occur in patients receiving allogeneic hematopoietic stem cell transplant (HSCT). GVHD occurs because of the immunological reaction between the donor’s T cells and the recipient’s antigens; GVHD may develop in different tissues, including the eye. Corneal perforation is an uncommon but vision-threatening manifestation of GVHD. We reported the case of a 65-year-old male patient who developed corneal perforation sequentially in both eyes 3 years afte [...]

by Carsten Croonenbroeck  and David Hennecke

Received: 06 February 2024;  Published: 15 March 2024;  doi: 10.21926/jept.2401008

We address the Wind Farm Layout Optimization (WFLO) problem and tackle the optimal placement of several turbines within a specific (wind farm) area by incorporating additional aspects of an economically driven target function. With this, we contribute three refinements for WFLO research: First, while many research contributions optimize the turbines' locations subject to maximum energy production or energy efficiency, we instead pursue a strategy of maximizing a profit objective. This enables us to incorporate inne [...]

by Sujeet Kumar Thakur  and Sambasivan Venkat Eswaran

Received: 17 June 2023;  Published: 01 September 2023;  doi: 10.21926/rpm.2303032

The Inert soil obtained from the Ghazipur Municipal Solid Waste landfill located in East Delhi, India has been used as the starting material for the work described in this paper. This mountain-like monster is often in the news for its bad smell, pollution of the groundwater in the area from its leachates, and the occasional fires in it endangering the lives of the people living nearby. Landfills produce many greenhouse gases (CO2, CH4, CO, HCHO, H2S, and NH3) which are poisonous and cause environmental pollution in [...]

by Raymond H. Baillargeon  , Marylène Charette  , François Tessier  and Kevin P. Brand

Received: 08 March 2022;  Published: 03 August 2022;  doi: 10.21926/obm.icm.2203031

The current recommendations of the Canadian Paediatric Society about monitoring children’s disruptive behaviors at well-child visits call for screening if behavioral concerns are being raised by parents. But do parents’ concerns about their child’s behavior constitute a reliable means for primary care providers (PCPs) to decide either in favor or against screening? We conducted a rapid systematic review of the literature by identifying documents that cited the landmark study by Glascoe and her col [...]

by Michael Falkenstein

Received: 11 August 2020;  Published: 19 August 2020;  doi: 10.21926/obm.geriatr.2003130