by Michael B. Keller  , Temesgen E. Andargie  and Sean Agbor-Enoh

Received: 16 March 2023;  Published: 26 June 2023;  doi: 10.21926/obm.transplant.2302190

Advances in the use of molecular biomarkers to guide management of lung transplant recipients are emerging. One such biomarker, donor-derived cell-free DNA (dd-cfDNA), has the potential to alter traditional approaches of lung transplant management, including the detection of acute rejection or infection, surveillance monitoring strategies, risk stratification of vulnerable patient populations and molecular phenotyping of various forms of allograft injury. The emergence of novel genetic and epigenetic approaches uti [...]

by Georgia Savvidou  , Spyratou Ellas  and Efstathios P Efstathopoulos

Received: 23 April 2024;  Published: 29 August 2024;  doi: 10.21926/rpm.2403022

Nanotechnology is one of the most promising fields of study, and it represents a pioneering leap in science and technology by the precise control over materials at the atomic and molecular level. This transformation affects numerous aspects of modern human life, including medicine, healthcare, electronics, computing, and energy storage. Nanotechnology has shown significant advancements in managing various health problems through different nano-formulations. These engineered nano-systems can be used as drug delivery [...]

by Ginevra G Adamo  , Sergio D'Angelo  , Angeli Christy Yu  , Marco Pellegrini  , Federico Bernabei  , Vincenzo Scorcia  and Giuseppe Giannaccare

Received: 17 June 2022;  Published: 02 August 2022;  doi: 10.21926/obm.transplant.2203164

Graft-versus-host disease (GVHD) is a serious complication that may occur in patients receiving allogeneic hematopoietic stem cell transplant (HSCT). GVHD occurs because of the immunological reaction between the donor’s T cells and the recipient’s antigens; GVHD may develop in different tissues, including the eye. Corneal perforation is an uncommon but vision-threatening manifestation of GVHD. We reported the case of a 65-year-old male patient who developed corneal perforation sequentially in both eyes 3 years afte [...]

by Mahmoud F. Elmorshedy  , Abualkasim Bakeer  and Dhafer Almakhles

Received: 14 February 2023;  Published: 09 May 2023;  doi: 10.21926/jept.2302017

The special design of linear induction machines (LIMs) leads to adverse effects caused by the longitudinal and end effects. These effects make the thrust control of the LIMs most attractive because its value decreases sharply with the speed increase. Thus, finite-state model predictive control (FS-MPC) is developed to increase the performance of the LIMs. However, the variable switching frequency is the main drawback of this control. Consequently, the main objectives of this paper are to propose FS-MPC with a const [...]

by Mohammed Mustafa  , Salman Pervaiz  and Ibrahim Deiab

Received: 23 February 2024;  Published: 18 June 2024;  doi: 10.21926/rpm.2402013

This paper investigates the effect of rake angle, α, cutting edge radius, r, and feed rate, f, on the cutting force and cutting zone temperature during orthogonal dry cutting of Ti6Al4V. A numerical model representative of the 2D orthogonal cutting process is developed using ABAQUS/Explicit software. Johnson-Cook, (JC) constitutive material model is used to describe material plasticity. JC damage model and energy-based fracture criterion are used to describe damage initiation and evolution. Using Minitab-19 softwar [...]

by Charles E. Carraher  , Michael R. Roner  , Jessica Frank  , Paul Slawek  , Francesca Mosca  , Kimberly Shahi  , Alisa Moric-Johnson  and Lindsey Miller

Received: 31 January 2019;  Published: 14 May 2019;  doi: 10.21926/obm.hg.1902019

Pancreatic cancer is the fourth leading cause of death in the USA. Treatment is seldom successful. A wide variety of organotin polymers exhibit good inhibition of human pancreatic cancer cell lines AsPC-1 and PANC-1. The AsPC-1 is an adenocarcinoma pancreatic cell line and PANC-1 which is an epithelioid carcinoma pancreatic cell line. Synthesis is rapid employing commercially available reactants and the interfacial polymerization that is employed in the commercial synthesis of aramids and polycarbonates.

by Meir Djaldetti  , Chiya Moshe Leibovitch  and Hanna Bessler

Received: 28 June 2020;  Published: 19 November 2020;  doi: 10.21926/obm.hg.2004053

The current study aimed to investigate the effect of a multi-species probiotic (MSP) on cytokine production by human peripheral blood mononuclear cells (PBMCs) and their immune dialogue with HT-29 colon cancer cells. PBMCs were incubated with MSP and their effect on cell proliferation and TNFα, IL-1β, IL-2, IL-6, IFNγ, IL-10, and IL-1ra production was evaluated. The impact of MSP on the cytokine production by PBMC stimulated by HT-29 cells was detected. Not-stimulated PBMC incubated with MSP showed increased produc [...]

by Aart Heesterman

Received: 29 November 2021;  Published: 28 November 2022;  doi: 10.21926/aeer.2204046

Around 1600 AD the carbon dioxide content of the earth’s atmosphere started to rise, even whilst according to the Milankovitch [1] astronomical theory of climate variation it was due to fall. On the natural earth the carbon dioxide count of the atmosphere is a delayed response and an enhancing feedback on the basic cause of the Milankovitch astronomical cycle, the intensity of the June sunshine. If the Milankovitch cycle had continued its natural course, the medevial cold period known as the little ice age. Human i [...]

by Mahdi Yousefi  , Scott Donne  , Shabnam Bahremand Abrasi  and Mohammad Yousefi

Received: 10 April 2023;  Published: 13 September 2023;  doi: 10.21926/jept.2303028

The thermal cracking of methane (TMC) is a significant reaction occurring above 850°C, which proceeds in two stages: non-isothermally and isothermally. However, most existing studies have focused on obtaining reaction rates under isothermal conditions [1], limiting their applicability to practical industrial reactor conditions. This novel research aims to determine the overall thermal decomposition rate of methane to hydrogen and carbon in adiabatic conditions, covering the range of unstable industrial reactor temp [...]

by Oreste Piccolo  , Elisabetta Parodi  and Antonella Petri

Received: 14 September 2022;  Published: 17 November 2022;  doi: 10.21926/cr.2204041

In this study, a PoC (Proof of Concept) of a possible biomass valorization of flax and camelina oilseed press cakes was presented. Biocatalyzed hydrolysis of residual oils and proteins extracted from these wastes was studied. The biotransformation of oils was performed using commercial immobilized lipases, including Amano PS, Amano AK, and Candida Antarctica Lipase B (CALB). Acylglycerols were partially or fully hydrolyzed using Amano PS and AK. Triglycerides were not hydrolyzed by CALB, which behaved differently. [...]