by Meir Djaldetti  , Chiya Moshe Leibovitch  and Hanna Bessler

Received: 28 June 2020;  Published: 19 November 2020;  doi: 10.21926/obm.hg.2004053

The current study aimed to investigate the effect of a multi-species probiotic (MSP) on cytokine production by human peripheral blood mononuclear cells (PBMCs) and their immune dialogue with HT-29 colon cancer cells. PBMCs were incubated with MSP and their effect on cell proliferation and TNFα, IL-1β, IL-2, IL-6, IFNγ, IL-10, and IL-1ra production was evaluated. The impact of MSP on the cytokine production by PBMC stimulated by HT-29 cells was detected. Not-stimulated PBMC incubated with MSP showed increased produc [...]

by Doo-Sung Lee

Received: 09 December 2020;  Published: 02 June 2021;  doi: 10.21926/rpm.2102021

This paper concerns a poroelastic half-space in which plane compressional waves are scattered by a spherical inclusion. Addition theorems for the spherical wave functions are utilized to meet the boundary conditions on the plane, and the satisfaction of the given conditions on the boundary of the sphere leads to three infinite series equations, whose solution can be acquired by successive approximations. Further, its existence and uniqueness are discussed.

by Navid Khaleghimoghaddam  and Sara Arzhangi

Received: 11 April 2025;  Published: 31 July 2025;  doi: 10.21926/obm.neurobiol.2503294

The acoustic design of indoor environments encompassing spatial configuration, material properties, and sound absorption significantly influences auditory perception and psychological well-being. This study examines the interaction between architectural acoustics, musical stimuli, and neural responses within a controlled therapeutic context, focusing on their effects on stress reduction and relaxation. Electroencephalography (EEG) was utilized to measure brain activity in 24 participants exposed to six musical inst [...]

by Tara Hickey  , Sarah Strohmaier  , Ellie Fossey  and Charlie Heriot-Maitland

Received: 21 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.icm.2402023

In the compassion focused therapy (CFT) model of voice-hearing, a distressing relationship with voices is thought to be influenced by evolved threat-protection patterns, which are activated and attuned by socially threatening experiences, such as being harmed by others, as well being shamed, stigmatised, invalidated, and excluded. Therefore, the CFT approach is particularly interested in the role of voice-hearers’ relationships with others and self, as well as their social context of family/friends, professio [...]

by Wanda Liguigli  , Rita Cengarle  , Anita Rimanti  , Giovanna Catania  , Laura Faglioni  , Simone Voltolini  , Carla Rabbi  , Roberto Barbieri  , Ilenia Zanardi Di Pietro  , Beatrice Vivorio  , Patrizia Morselli  , Chiara Iridile  , Laura Rigotti  and Maurizio Cantore

Received: 26 October 2022;  Published: 27 March 2023;  doi: 10.21926/obm.geriatr.2301230

Comprehensive Geriatric Assessment (CGA) is utilized to plan social and health care of the elderly and to complete the diagnostic-therapeutic choice of oncologist also considering early integration with palliative care. Cancer patients (pts) hospitalized aged ≥70 years were screened by the G8 questionnaire to define if necessary CGA. CGA identified: fit, unfit and frail pts. We screened 95 pts by G8 and 93 (98%) were at risk. Pts at risk, evaluated by CGA resulted: 3 fit, 45 unfit and 45 frail. 3 fit pts received s [...]

by Amjad Mizyed

Received: 23 December 2024;  Published: 21 April 2025;  doi: 10.21926/jept.2502007

Water scarcity is one of the most pressing global challenges, particularly in arid and semi-arid regions. In this context, the Gaza Strip, where groundwater is the only available natural water resource, faces severe water stress due to overexploitation and drought conditions. This study aimed to review the recent water budget for the Gaza Strip by collecting data for the years (2021-2022) which was analyzed, discussed, and compared with other studies. The results showed a sharp deterioration in the Gaza Strip in te [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by Dipti Nikam  and Abbas S. Milani

Received: 05 May 2022;  Published: 24 April 2023;  doi: 10.21926/rpm.2302017

This study evaluates the influence of different loading angles and the area of loading on the ensuing stress distribution and the physical response of a natural central incisor tooth, using a 3D finite element analysis. The CAD model of the incisor tooth assembly (including enamel, dentin, periodontal ligament, pulp, gingiva and jaw bone) was subject to an external (chewing) load of 100 N, over four different areas and at four different angles along the vertical. It was observed that the tooth experiences high von- [...]

by Charles E. Carraher  , Michael R. Roner  , Jessica Frank  , Paul Slawek  , Francesca Mosca  , Kimberly Shahi  , Alisa Moric-Johnson  and Lindsey Miller

Received: 31 January 2019;  Published: 14 May 2019;  doi: 10.21926/obm.hg.1902019

Pancreatic cancer is the fourth leading cause of death in the USA. Treatment is seldom successful. A wide variety of organotin polymers exhibit good inhibition of human pancreatic cancer cell lines AsPC-1 and PANC-1. The AsPC-1 is an adenocarcinoma pancreatic cell line and PANC-1 which is an epithelioid carcinoma pancreatic cell line. Synthesis is rapid employing commercially available reactants and the interfacial polymerization that is employed in the commercial synthesis of aramids and polycarbonates.

by John Konstantaras  , Christos Pagkalos  , Maria K. Koukou  , Kostas Lymperis  , Yannis Caouris  and Michail Gr. Vrachopoulos

Received: 17 April 2022;  Published: 09 June 2022;  doi: 10.21926/jept.2202021

In this study, the performance of a self-sufficient controller used for a solar-latent heat domestic hot water (DHW) production unit under real-world operating conditions was analyzed. The unit consists of a flat-plate solar collector and a latent heat storage tank. The controller is powered by a small solar panel and governs the charging and discharging of the system, ensuring maximum solar energy absorption, desired hot water temperature, and constant monitoring of the heat-storage tank’s capacity. The system is [...]