by Esra Pehlivan

Received: 11 December 2024;  Published: 03 March 2025;  doi: 10.21926/obm.transplant.2501239

Cystic fibrosis (CF) is a genetic disorder that significantly impacts respiratory function, leading to progressive lung damage and ultimately respiratory failure. Lung transplantation (LTx) is a critical intervention for CF patients with end-stage lung disease, offering improved survival and quality of life. Pulmonary rehabilitation (PR) plays a pivotal role both preoperatively and postoperatively in optimizing outcomes for LTx candidates and recipients. Pre-transplant PR interventions, including exercise programs, [...]

by Rene J. Duquesnoy

Received: 11 July 2018;  Published: 05 September 2018;  doi: 10.21926/obm.transplant.1803018

The Holy Grail to Clinical Transplant Tolerance is Paved with HLA Epitopes

by Rafael B. Oliva  , Andrés Zappa  , Mariano Amadio  and Guillermo Catuogno

Received: 31 October 2024;  Published: 05 May 2025;  doi: 10.21926/jept.2502009

This work addresses the main results of a test site for small wind turbines (SWTs) located in Patagonia, and the development of the measurement systems involved, including the uncertainties calculations according to applicable IEC standards. Due to market evolution for over a decade, the test systems evolved from battery-charging SWTs to grid-connected units. The test site, developed and managed by state-owned INTI (National Institute for Industrial Technology), was established in 2012 and received support from the [...]

by S.Amitha Banu  and Khan Sharun

Received: 25 May 2023;  Published: 02 June 2023;  doi: 10.21926/obm.transplant.2302187

Platelet-rich plasma (PRP) is a promising tool in regenerative medicine because it stimulates tissue repair and regeneration. PRP contains a high concentration of platelets, growth factors, and cytokines involved in the healing process. This editorial paper aims to give an overview of PRP in regenerative medicine and its potential applications in various medical fields such as orthopedics, dentistry, dermatology, and wound healing. PRP can be integrated with other regenerative therapies, such as stem cell and gene [...]

by Filippo Lixi  , Benedetta Pintus  and Giuseppe Giannaccare

Received: 27 February 2024;  Published: 07 June 2024;  doi: 10.21926/obm.transplant.2402218

Calcareous corneal degeneration is a rare disease characterized by calcium phosphate deposition into the deep corneal layers. Corneal calcification has a multifactorial origin and is associated with various systemic and ocular conditions. Several treatment options showed promising results in the management of this disorder. Herein, two cases of calcareous degeneration occurring postoperatively in patients undergoing surgery for retinal detachment (case #1) and glaucoma (case #2) were reported. Despite normal serum [...]

by Byron J. Hoogwerf

Received: 09 July 2024;  Published: 20 February 2025;  doi: 10.21926/obm.geriatr.2501299

Sarcopenia is more common in persons with type 2 diabetes mellitus (T2DM) than in persons without diabetes. There is overlap of some pathophysiologic features of sarcopenia and T2DM. In addition, the risk for sarcopenia is associated with common complications of T2DM including renal disease, cardiovascular disease and neuropathy. Glycemic control in T2DM may have some benefits on sarcopenia. The specific effects of glucose lowering agents on sarcopenia suggest that metformin, insulin, thiazolidinediones and GLP1 re [...]

by Elga J. Vargas  , Julio C. Martinez  and Lina A. Gomez

Received: 26 April 2024;  Published: 03 October 2024;  doi: 10.21926/obm.transplant.2404225

Acne is a chronic inflammatory condition affecting the pilosebaceous units of the skin, characterized by the formation of papules, cysts, comedones, pustules, nodules, and scars. These lesions are typically located on the face and shoulders, although they can extend to the trunk, arms, and legs. In regenerative medicine, biomolecules are fundamental to tissue regeneration. The use of growth factors from autologous platelet-rich plasma emerges as a promising alternative in the treatment of acne and scars. This study [...]

by Giuseppe Cocco  , Hans Peter Hofmann  and Stefano Pandolfi

Received: 27 December 2023;  Published: 11 March 2024;  doi: 10.21926/obm.geriatr.2401273

Heart failure is one of the major health threats in Western societies, and its prevalence is steadily increasing. Many data show the important impact of sex (biological) and gender (sociocultural) differences on most aspects (diagnosis, etiology, treatments, and outcomes) of heart failure. For example, compared to men, women with heart failure are older, have more co-morbidities, and develop different phenotypes of heart failure. Postpartum cardiopathy is unique in women. The iatrogenic effects of cancer therapies [...]

by Hidehiro Kamezaki  , Tatsuo Kanda  , Osamu Yokosuka  , Yasunori Kasahara  and Takayuki Sakurai

Received: 16 November 2016;  Published: 21 January 2017;  doi: 10.21926/obm.hg.1701001

(1) Background: Preventative treatment for Pneumocystis jirovecii pneumonia (PCP) has been recommended for patients receiving ≥20 mg/day prednisolone. We describe a patient who developed PCP while receiving a dose of 15 mg/day prednisolone, and consider criteria for the initiation of preventative therapy for PCP in patients with autoimmune hepatitis (AIH) treated with prednisolone. (2) Case Report: A 71-year-old woman initially possessed dark-colored urine, white stool, and decreased appetite, which indicated hepat [...]

by Sujeet Kumar Thakur  and Sambasivan Venkat Eswaran

Received: 17 June 2023;  Published: 01 September 2023;  doi: 10.21926/rpm.2303032

The Inert soil obtained from the Ghazipur Municipal Solid Waste landfill located in East Delhi, India has been used as the starting material for the work described in this paper. This mountain-like monster is often in the news for its bad smell, pollution of the groundwater in the area from its leachates, and the occasional fires in it endangering the lives of the people living nearby. Landfills produce many greenhouse gases (CO2, CH4, CO, HCHO, H2S, and NH3) which are poisonous and cause environmental pollution in [...]