Immune Senescence and Covid-19 Pandemic
Abstract
1699 8107
Immune Senescence and Covid-19 PandemicAbstract
Covid-19 pandemic has been infecting a substantial portion of the world population, thereby revealing quality deficits in health care in the majority of the countries around the globe. Severe illness and mortality from Covid-19 infection are present predominantly in minorities; especially they are more frequent in geriatric patients. Unfortunately, our knowledge is limited about what accounts for the variability in immune response from one person to another. This question is far from being merely academic, and find [...] 1699 8107 |
A Mixed-Methods Pilot Study to Identify Facilitators Leading to Sustained Mindfulness Practice across the Perinatal Periodby
Abstract
Many women experience depression and/or anxiety during pregnancy and/or the postpartum period. Mind-Body Interventions (MBIs) have shown great efficacy in the mitigation of these symptoms; however, there is limited research spanning the postpartum period and exploring long-term sustainability of mindfulness practice. Furthermore, little is known about specific facilitators that contribute to sustainability. The primary objective of this mixed-methods study is to use the Theory of Planned Behavior (TPB) framework to [...] 1464 8107 |
An Evidence of Drug Repurposing for COVID-19 Pandemic Based on In silico Investigation from Phenolic Derivatives of Silybum Marianum Against SARS-Cov-2 ProteinsAbstract
The outbreak of coronavirus disease-2019 (COVID-19) had a striking impact on the worldwide healthcare system within a very short period. The availability of a large number of clinical data on SARS-CoV-2, conventional precautionary majors, and treatment strategies with the existing therapeutic antiviral drug molecules also fails to control progression and disease transmission among the population. Hence, we implemented pharmacoinformatics approaches to facilitate the drug discovery by repurposing naturally available [...] 1155 8106 |
Indoor Built Environments Attended by Primary School Children and Its Microbiology: A Cross-Project Studyby
Abstract
Exposure to indoor pollutants may exert a significant effect on children health as they spend most of their time in enclosed environments. This research compared the association of biological concentrations with indoor characteristics and building materials in places where children spend significant time indoors. It was compared the results of two autonomous research projects conducted in Porto primary schools and households. Both the projects included a walkthrough inspection and biological measurements in indoor [...] 1238 8106 |
Compassion in Medicine – A Psychiatric Physician’s ViewAbstract
There are several definitions of sympathy, empathy, and compassion on the internet. I have chosen the above definitions to emphasize their salient differences, for the following reason: In medical school, in the early 1960s, we were taught not to sympathize with patients, but to empathize: By empathizing, one can retain some professional objectivity toward the patient, in order to be of some help. To sympathize, on the other hand, was to immerse oneself in the patient’s suffering and lose one’s professional per [...] 1596 8104 |
Hereditary Pancreatitis – A Review of Current Concepts and ManagementAbstract
(1) Background: Hereditary Pancreatitis is a rare cause of acute pancreatitis. These patients usually present at a young age with recurrent episodes of acute pancreatitis that usually progresses to chronic pancreatitis with associated endocrine and exocrine failure. Hereditary pancreatitis also carries an increased lifetime risk of pancreatic adenocarcinoma. These high risk patients need early intervention where appropriate by specialist multidisciplinary teams and tailored long term management.
(2) Methods [...] 1277 8102 |
Clinical Features, Genetic Landscape and Management of Behçet's Syndrome: A Comprehensive Reviewby
Abstract
Behçet's syndrome is a systemic inflammatory disorder of unknown origin, presenting with diverse symptoms such as recurrent oral and genital ulcers, skin lesions, and uveitis, and can impact multiple organ systems. Diagnosis relies primarily on clinical evaluation due to the lack of specific diagnostic tests. Management requires a multidisciplinary approach to control inflammation and alleviate symptoms, utilizing treatments like corticosteroids, immunosuppressive agents, and biological therapies. The higher preval [...] 658 8098 |
Challenges of Applying Circular Economy in Agricultural Sustainable Development: A Case Study of Kurdistan Province, IranAbstract
Current production and distribution models in agriculture primarily operate based on the 'linear economy' approach. This means that after the exploitation of natural resources and the production of the final product, a significant portion of these resources and products, now contaminated or turned into waste, exit the economic cycle. The circular economy approach in agriculture seeks to reuse waste products and depleted inputs, thereby reducing the intensity of resource exploitation and taking a step towards sustai [...] 1464 8097 |
Coping and Managing ALS Disease in the Family during COVID-19: Caregivers' Perspectiveby
Abstract
Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons, the nerve cells in the brain and the spinal cord that enable voluntary muscle movement. Managing ALS is complex and increasingly requires informal care, most often by the patient's companions/spouses or children. The COVID-19 pandemic posed additional critical issues, particularly the disruption of home care and the increased time caregivers spent on patient care. One aim of this research was to assess caregiv [...] 1105 8093 |
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