Table of Content

Open Access Original Research

How Can Architectural Acoustics Reflect Levels of Stress and Relaxation in Indoor Environments? An EEG-Based Experimental Study

Received: 11 April 2025;  Published: 31 July 2025;  doi: 10.21926/obm.neurobiol.2503294

Abstract

The acoustic design of indoor environments encompassing spatial configuration, material properties, and sound absorption significantly influences auditory perception and psychological well-being. This study examines the interaction between architectural acoustics, musical stimuli, and neural responses within a controlled therapeutic context, focusing on their effects on stress reduction and relaxation. Electroencephalography (EEG) was utilized to measure brain activity in 24 participants exposed to six musical inst [...]

1468 8904

Open Access Short Communication

Mental Health among the Elderly in Nepal: Special Emphasis on Depression

Received: 21 December 2023;  Published: 08 February 2024;  doi: 10.21926/obm.geriatr.2401268

Abstract

This paper discusses the impact of Depression on the aging population. It also tries to explore the psychosocial risk factors and burden associated with geriatric depression in low-and-middle-income (LAMI) countries. Nepal, a South Asian developing country, is resource-poor and research-naïve. Research, in general, and mental health studies, in particular, are the least prioritized in this country. The lack of culturally adapted psychiatric inventories is one of the possible reasons for the low number of mental hea [...]

1504 8903

Open Access Review

Emerging Roles of Signal Transduction Pathways in Neurodegenerative Diseases. Hunting New Possible Therapeutic Molecular Targets

Received: 27 January 2023;  Published: 05 May 2023;  doi: 10.21926/obm.geriatr.2302234

Abstract

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable populations of neurons in specific regions of the central nervous system was traced to different pathological events, such as misfolded proteins’ accumulation, abnorma [...]

1389 8889

Open Access Original Research

Zn(OCOCH3)2·2H2O Catalysed Efficient Preparation of 2-Phenyl-4-Arylmethylidene-5-Oxazolinones under Ultrasonic Condition

Received: 30 September 2022;  Published: 15 February 2023;  doi: 10.21926/cr.2301007

Abstract

2-Phenyl-4-arylmethylidene-5-oxazolinones were synthesized in very high yield by subjecting a mixture of an aryl aldehyde/heterocyclic aldehyde/cinnamaldehyde and hippuric acid in anhydrous acetic anhydride and catalytic Zn(OCOCH3)2·2H2O to ultrasonication at 35 KHz for 4 to 8 min. This method has many advantages: use of a green catalyst; yields are high, involves easy workup procedure, is energy efficient and economically feasible.

1801 8872

Open Access Research Article

Effects of Coenzyme Q10 on H2O2-Induced Oxidative Stress of Human Keratinocytes

Received: 05 July 2024;  Published: 06 January 2025;  doi: 10.21926/obm.genet.2501279

Abstract

Keratinocytes are particularly vulnerable to oxidative stress due to their function as the primary natural protective barrier exposed to chemicals, rays, and pollution to stimulate the formation of free radicals in the body. Two factors of interest correlate with cellular senescence under oxidative stress. These include regulating antioxidant synthesis, which maintains free-radical homeostasis through the Nrf2 gene, and the prevention of telomere shortening, which involves the collaboration of human telomerase gene [...]

1639 8870

Open Access Short Communication

Targeted MRI (tMRI) of Small Increases in the T1 of Normal Appearing White Matter in Mild Traumatic Brain Injury (mTBI) Using a Divided Subtracted Inversion Recovery (dSIR) Sequence

Received: 30 June 2023;  Published: 14 December 2023;  doi: 10.21926/obm.neurobiol.2304201

Abstract

In modelling studies targeted MRI (tMRI) of small increases in the T1 of tissues using divided Subtracted Inversion Recovery (dSIR) sequences show ten or more times the contrast seen with conventional IR sequences. This may be particularly useful in imaging normal appearing white matter where there may be small changes in T1 and/or T2 in disease but these changes may be insufficient to produce useful contrast with conventional T2-weighted spin echo (T2-wSE) and T2-FLuid Attenuated Inversion Recovery (T2-FLAIR) sequ [...]

1637 8866

Open Access Original Research

Improving Confidence in Dementia Care by Helping Care Staff Articulate Skills They Already Possess: The Value of the Communication and Interaction Training (CAIT) Programme

Received: 14 August 2022;  Published: 18 January 2023;  doi: 10.21926/obm.geriatr.2301222

Abstract

This article discusses the findings from a training programme called ‘Communication and Interaction Training’ (CAIT). CAIT was designed to improve the confidence of carers in their use of communication skills with people living with dementia, particularly when managing behavioural agitation. This pre/post assessment study employed a mixed design, and showed positive effects in terms of quantitative and qualitative features. The participants were mainly from a specialist team who were experienced in managing episode [...]

1476 8856

Open Access Editorial

‘Digital Chinese Medicine (DCM)’: From Acupuncture to Algorithms and the Digital Transformation of Traditional Chinese Medicine (TCM)

Received: 19 November 2023;  Published: 20 November 2023;  doi: 10.21926/obm.icm.2304054

Abstract

In today's high-tech-driven times, traditional ways are getting a digital upgrade, and Chinese medicine is part of this change. Mixing ancient healing know-how with modern high technology has created digital Chinese medicine (DCM). It could change healthcare worldwide. This editorial aims to explore this new area and look at its possibilities, challenges, and how it might affect healthcare in the future. It lists some essential topics that need to be considered in the future within the digital transformation of Chi [...]

1372 8853

Open Access Communication

Linking Population and Forest Dynamics over the Conterminous US for the 1990s and 2000s

Received: 24 September 2020;  Published: 09 March 2021;  doi: 10.21926/aeer.2101003

Abstract

Few studies have investigated deforestation and population connections in the U.S. at large spatial extents or small scales. We examined forest cover changes over two decades, 1990-2000 and 2000-2010, in the continental U.S. at the county scale. Forest dynamics were estimated using the National Land Cover Database, a satellite-derived classification product and then linked to population data from the US. Census. At the aggregate level, high population growth seems to increase net forest loss in a non-linear manner, [...]

1355 8850

Open Access Original Research

Nonlinear Optimal Control for Six-Phase Induction Generator-Based Renewable Energy Systems

Received: 07 December 2022;  Published: 11 May 2023;  doi: 10.21926/jept.2302018

Abstract

The article aims at optimizing six-phase induction generator-based renewable energy systems (6-phase IGs or dual star induction generators) through a novel nonlinear optimal control method. Six-phase induction generators appear to be advantageous compared to three-phase synchronous or asynchronous power generators, in terms of fault tolerance and improved power generation rates. The dynamic model of the six-phase induction generator is first written in a nonlinear and multivariable state-space form. It is proven th [...]

1340 8847

TOP