by Richard Cheng  and Jon Kobashigawa

Received: 23 January 2019;  Published: 09 April 2019;  doi: 10.21926/obm.transplant.1902061

Cardiac allograft vasculopathy (CAV) limits long-term survival after heart transplantation. CAV with discrete or tubular lesions can be treated with percutaneous coronary intervention (PCI) with high procedural success. Revascularization with balloon angioplasty, bare-metal stents, and first-generation drug-eluting stents has been associated with high and unacceptable restenosis rates. However, second-generation drug-eluting stents are associated with favorable stent and lesion patency. Stent and lesion patency now [...]

by Mariya Shiyko

Received: 17 July 2018;  Published: 08 November 2018;  doi: 10.21926/obm.icm.1804029

What is meditation? A tool that empowers you to create your life through working it from inside out, beginning with a thought. There is a story. A father had two sons: one felt a victim of life. He viewed his life through the prism of “My childhood was difficult. My father was an alcoholic. The reason my life is failing is because of that. I was not loved enough.” This is his inner mantra – a cycle of a repetitive thought patterns that he continuously told himself. His life followed that very mantra. He didn’t try [...]

by Jessica Lum  and Sherif B. Mossad

Received: 26 October 2018;  Published: 14 February 2019;  doi: 10.21926/obm.transplant.1901050

Despite the advances that have been made in the field of solid organ transplant (SOT), organ shortage remains a persistent problem. In addition, the donor pool has been changing with the ongoing opioid epidemic and increase in deaths related to drug overdose each year. More donors are meeting the 2013 United States (U.S.) Public Health Service criteria for increased risk donors (IRDs), or donors who are at higher risk for transmission of Human Immunodeficiency Virus (HIV), Hepatitis C virus (HCV), and other multidr [...]

by Joep Geraedts

Received: 13 January 2020;  Published: 14 January 2020;  doi: 10.21926/obm.genet.2001102

At the beginning of a new year it is always good to look both backwards and forwards and to highlight a few items that are relevant with respect to the long-term development of our journal. As everybody knows, the principle of open access publishing is that the authors pay fees (the article‐processing charges or APCs) to publish in the journal rather than that the readers pay subscription costs for the journal. Three years ago, OBM Genetics started as an open access journal publishing its first papers totally free [...]

by Rama Jaiswal  , Melad Shaikh  and Kalluri V. S. Ranganath

Received: 01 June 2023;  Published: 21 November 2023;  doi: 10.21926/cr.2304028

A surface modification approach has prepared a nanostructured organic framework connecting two metal oxide NPs. The surface modifier attached two metal oxide NPs via molecular interaction to generate modular structures of fiber, rod, or sponge materials. Thus, obtained hybrid systems have been confirmed through FT-IR, TGA, PXRD, and SEM. Metal oxides such as Fe3O4 and MgO generated mixed materials via the surface modification approach. Thus, obtained materials have been successfully used to dehydrate biomass-derive [...]

by Jacqueline Cramer

Received: 24 September 2023;  Published: 21 November 2023;  doi: 10.21926/aeer.2304050

This paper investigates the practical implementation of transitioning to a circular economy through network governance in conjunction with public governance. The research focuses on a comparative, longitudinal analysis of three Dutch product chains (mattresses, concrete, and textiles) from 2016 to the present. The study based on action research, utilizes documents, reports from all meetings, and personal observations. Drawing from the fields of public administration and transition management, the paper addresses tw [...]

by Seria Tsan  , Stefanie Kankel  , Niklas Padutsch  , Luisa Person  , Monika Ziegler  , Ahmed Al-Rikabi  , Anja Weise  , Kristin Mrasek  and Thomas Liehr

Received: 16 April 2021;  Published: 25 August 2021;  doi: 10.21926/obm.genet.2103135

Cryptic balanced chromosomal aberrations can be an underlying cause of infertility. In 2003 Cockwell and coworkers highlighted the relevance of euchromatic pericentric regions of acrocentric chromosomes that may be a yet ignored genomic region hosting cryptic rearrangements. Here we offer the first follow-up study to further explore this idea. Two specific molecular cytogenetic probe sets were established to elucidate such cryptic rearrangements together with chromosomal heteromorphisms of acrocentric centromeres. [...]

by Jennifer A. King  , Megan R. Holmes  , Kylie Evans  , Anna E. Bender  and Dakota King-White

Received: 28 February 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303036

The COVID-19 pandemic exacerbated the long-standing issues of stress and burnout in the education sector, with teachers and education staff facing unprecedented challenges including significant adjustments to teaching methods and balancing the mental health and academic needs of their students. The resulting challenges have contributed to heightened levels of stress and burnout among teachers and education staff. The impact of the pandemic on teachers and education staff has highlighted the need for greater support [...]

by Solaf Alaakel  and Youssef. AL-Ammouri

Received: 29 July 2023;  Published: 26 October 2023;  doi: 10.21926/obm.genet.2304200

The experiment was carried out at the laboratories of the National Commission for Biotechnology in Syria during the period 2020-2022 to detect the somaclonal genetic variation occurring in callus cultures at different ages and to compare them with the In vitro growing plants and introduced species of Rose Periwinkle that grew up in the Syrian environment, in addition, exploring the effect of abiotic stresses in causing genetic variations in callus, by the Inter Simple Sequence Repeats technique (ISSR) using 21 prim [...]

by Anita Modi  and Sherif Beniameen Mossad

Received: 07 July 2019;  Published: 06 September 2019;  doi: 10.21926/obm.transplant.1903085

Chronic inflammatory states lead to T cell exhaustion, characterized by reduced T cell proliferation and activity. Immune checkpoint inhibitors (ICPI) reactivate T cells to restore the immune system’s natural defenses against foreign antigens. The widespread use of these agents in the treatment of malignancy has led to markedly reduced tumor burden and improved patient survival, sparking curiosity about their potential role in the treatment of other chronic inflammatory states, including infectious diseases. While [...]