by Mariya Shiyko

Received: 17 July 2018;  Published: 08 November 2018;  doi: 10.21926/obm.icm.1804029

What is meditation? A tool that empowers you to create your life through working it from inside out, beginning with a thought. There is a story. A father had two sons: one felt a victim of life. He viewed his life through the prism of “My childhood was difficult. My father was an alcoholic. The reason my life is failing is because of that. I was not loved enough.” This is his inner mantra – a cycle of a repetitive thought patterns that he continuously told himself. His life followed that very mantra. He didn’t try [...]

by Christiana Chioma Efe-Onakpojeruo  , Mehdi Seraj  and Huseyin Ozdeser

Received: 11 March 2024;  Published: 26 September 2024;  doi: 10.21926/aeer.2403018

This study addresses the critical issue of carbon dioxide (CO2) emissions, focusing on understanding the intricate interplay between four major variables Gross Domestic Product per capita (GDPC), Renewal Energy (RE), Fossil Fuel energy consumption (FF), and Patent application (PTS). This research is crucial due to the emerging negative impacts of climate change, which will create a disastrous future for human beings. It focuses on three decades from 1990 to 2020 and compares the results between the United States an [...]

by Enrico Capobianco

Received: 15 June 2020;  Published: 30 December 2020;  doi: 10.21926/obm.neurobiol.2004077

Marks of brain disorders may be visible through abnormal networks characterized by states with distinct signatures or connectivity patterns. Apart from neurodegenerations, drug abuse or eventually addiction may exert complex perturbative effects over human health, including damage to various organs and especially brain inflammation, volume shrinkage and functional deficits. These can also be regarded as signs of accelerated ageing, which involve multiple comorbidities associated with long-lasting cognitive impairme [...]

by Solaf Alaakel  and Youssef. AL-Ammouri

Received: 29 July 2023;  Published: 26 October 2023;  doi: 10.21926/obm.genet.2304200

The experiment was carried out at the laboratories of the National Commission for Biotechnology in Syria during the period 2020-2022 to detect the somaclonal genetic variation occurring in callus cultures at different ages and to compare them with the In vitro growing plants and introduced species of Rose Periwinkle that grew up in the Syrian environment, in addition, exploring the effect of abiotic stresses in causing genetic variations in callus, by the Inter Simple Sequence Repeats technique (ISSR) using 21 prim [...]

by Jennifer A. King  , Megan R. Holmes  , Kylie Evans  , Anna E. Bender  and Dakota King-White

Received: 28 February 2023;  Published: 07 September 2023;  doi: 10.21926/obm.icm.2303036

The COVID-19 pandemic exacerbated the long-standing issues of stress and burnout in the education sector, with teachers and education staff facing unprecedented challenges including significant adjustments to teaching methods and balancing the mental health and academic needs of their students. The resulting challenges have contributed to heightened levels of stress and burnout among teachers and education staff. The impact of the pandemic on teachers and education staff has highlighted the need for greater support [...]

by Mariette Kokolo  and Montse Bach-Elias

Received: 25 June 2020;  Published: 16 November 2020;  doi: 10.21926/obm.genet.2004118

Non-coding RNAs (ncRNAs) have emerged as one of the most abundant regulatory molecules. However, their roles and functions are significantly different from those of proteins. Moreover, around 95% of the human genome contains non-coding DNA. ncRNAs contribute by far the majority of human transcriptional units, and the functions of the most are yet unknown. Here, we highlight that an important RNA sequence region, encompassing an exon-intron hairpin loop (also called IDX-rasISS1), of the H-Ras pre-mRNA may encode an [...]

by Vjollca Ndreu  , Yllka Themeli  , Ilirjana Zekja  and Fatjona Kamberi

Received: 02 April 2022;  Published: 06 July 2022;  doi: 10.21926/obm.neurobiol.2203126

The World Health Organization declared the COVID-19 pandemic on March 11th, 2020. The pandemic had significantly affected public health, and the mental health of people was compromised regardless of age or socioeconomic status. In this study, we measured the psychological distress caused by the pandemic and determined the associated factors. An online survey was conducted from November 16th (2020) to January 31st (2021). The participants were Albanian adults (≥18 years old). The call to participate was poste [...]

by Abhijit Jagdale  , C. Adam Banks  , Hayato Iwase  , David K.C. Cooper  and Hidetaka Hara

Received: 29 December 2020;  Published: 30 June 2021;  doi: 10.21926/obm.transplant.2102146

It has been speculated that the immunomodulation associated with pregnancy, e.g., decreasing pro-inflammatory cytokines, increasing anti-inflammatory cytokines, upregulation of T regulatory cells (Tregs), is in part due to the effect of human chorionic gonadotropin (hCG). In this study, we tested the effect of hCG on proliferation of human peripheral blood mononuclear cells (PBMCs) stimulated by irradiated pig PBMCs. Mixed lymphocyte reaction (MLR) was carried out with human PBMCs as responders and irradiated wild- [...]

by Roberto Anaya-Fernández  , Roberto Anaya-Prado  , Michelle M. Anaya-Fernández  , Miguel A. Guerrero-Palomera  , Ivan F. Garcia-Ramirez  , Daniel Gonzalez-Martinez  , Consuelo C. Azcona-Ramirez  , Citlalli S. Guerrero-Palomera  , Claudia Garcia-Perez  , Bernardo Tenorio-Gonzalez  , Jose E. Tenorio-Gonzalez  , Laisha F. Vargas-Ascencio  , Abraham I. Canseco-Villegas  , Gustavo Servin-Romero  , Allen R. Barragan-Arias  and Bruno Reyna-Rodriguez

Received: 02 May 2024;  Published: 07 August 2024;  doi: 10.21926/obm.neurobiol.2403239

Oxidative stress in cerebral ischemia/reperfusion injury (CIRI) involves reactive oxygen and nitrogen species (ROS and RNS). Despite efficient antioxidant pathways in the brain, hypoxia triggers the production of oxygen free radicals and downregulates ATP, which leads to oxidative stress. Sources of free radicals during CIRI include Ca2+-dependent enzymes, phospholipid degradation and mitochondrial enlargement. Upon reperfusion, the abrupt increase of oxygen triggers a massive radical production via enzymes like xa [...]

by Andreea L. Seritan

Received: 26 November 2021;  Published: 24 January 2022;  doi: 10.21926/obm.geriatr.2201187

Older adults’ mental health needs significantly increased during the COVID-19 pandemic. Geriatric psychiatry is an area of extreme workforce shortage globally. A novel curriculum was developed to educate healthcare providers on COVID-19-related geriatric and geropsychiatry topics. Monthly lectures were presented from November 2020 to June 2021. Evaluations were collected after each lecture via an anonymous survey. Overall lecture quality and relevance for the participants’ clinical practices were rated on a 1-3 Lik [...]