Table of Content

Open Access Review

Allogeneic Hematopoietic Cell Therapies to Induce Tolerance in Kidney Transplantation

Received: 29 October 2018;  Published: 20 November 2018;  doi: 10.21926/obm.transplant.1804027

Abstract

This review summarizes the latest results from the interventional clinical trials for inducing clinical tolerance in the recipients of human leukocyte antigen (HLA)-matched or mismatched living donor kidney transplants via allogeneic hematopoietic stem cell (HSC)-based therapies. The protocols utilized by the three medical centers in the United States differ in degree of HLA-matching, relatedness or unrelatedness, donor cell composition of the hematopoietic stem cells transplant (HSCT), timing for infusion and cond [...]

1487 9056

Open Access Case Report

Prolonged Maintenance of Remission with Crohn Disease Exclusion Diet (CDED) in Two Siblings with Crohn Disease

Received: 23 August 2024;  Published: 13 December 2024;  doi: 10.21926/rpn.2404020

Abstract

Dietary and nutritional interventions have been shown to have roles in managing active Crohn disease (CD), with exclusive enteral nutrition (EEN) being recommended as the preferred initial treatment in children following diagnosis. In recent years, other nutritional interventions such as the Crohn's disease exclusion diet (CDED) have been considered and evaluated for induction therapy. To date, the long-term benefits of CDED have not been established. This report highlights the outcomes of the prolonged use of CDED [...]

1276 9053

Open Access Original Research

Preparation & Characterization of Polyvinyl Alcohol-Sodium Alginate-Starch Based Hydrogel by Gamma Radiation and Its Application for the Treatment of Dye Containing Water

Received: 04 September 2023;  Published: 02 November 2023;  doi: 10.21926/aeer.2304048

Abstract

Hydrogels are three-dimensional, hydrophilic networks of polymers with a high water absorption capacity. We investigated the removal of monovalent cationic dye, methylene blue, from aqueous solutions by a polyvinyl alcohol/Sodium alginate/Starch mix hydrogel to discover a solution to the environmental waste-water problem. By applying a gamma radiation dose from a Co-60 source without adding a hazardous cross-linker, a novel PVA/SA/Starch mix hydrogel was synthesized. The effects of factors like irradiation dose and [...]

1458 9052

Open Access Research Article

Corporate Digital Responsibility and the Business Implications of Quantum Computing

Received: 06 September 2023;  Published: 07 December 2023;  doi: 10.21926/aeer.2304053

Abstract

While artificial intelligence has been attracting increasing investment and controversy, a new, and potentially much more powerful technology, Quantum Computing, is on the business horizon. Already, organizations are assessing its potential for addressing a range of computationally challenging issues, such as last-mile optimization and cryptanalysis to break encryption algorithms, and are exploring possible applications in a range of business areas. While the advent of Quantum Computing may bring an array of opport [...]

1367 9052

Open Access Case Report

Dietary Supplements in Dyslipidemia

Received: 04 March 2018;  Published: 23 May 2018;  doi: 10.21926/obm.icm.1802008

Abstract

Lifestyle and dietary interventions can have a significant impact on patients with dyslipidemia and should be encouraged with the use of dietary supplements. With new research, there is evidence that using dietary supplements, specifically nutraceuticals can be helpful for cholesterol management. Four commonly used supplements are: Red Yeast Rice, Omega 3 Fatty Acids, Niacin and Berberine.

1756 9051

Open Access Short Review

Alzheimer's Disease: Parsing the Pathways Leading to the Disease Based on the Spirochete/Biofilm Hypothesis

Received: 30 December 2019;  Published: 19 February 2020;  doi: 10.21926/obm.geriatr.2001107

Abstract

A pathway which highlighted spirochetes (Borrelia burgdorferi and dental treponemes) that made biofilms which led to Alzheimer’s disease has recently been promulgated. All the Alzheimer’s disease, on which this pathway was based, had been specifically confirmed both clinically and pathologically. This current work will show putative and plausible individual pathways that were studied. First and foremost, intracellular spirochetes make biofilms and concurrently make beta amyloid; this has been shown in v [...]

1474 9048

Open Access Original Research

Thermo-rechargeable Batteries Fabricated Using Low-cost Materials

Received: 15 February 2022;  Published: 30 March 2022;  doi: 10.21926/jept.2201011

Abstract

We fabricated three thermo-rechargeable batteries using low-cost transition metal hexacyanoferrate and determined the thermal voltage (Vcell) and discharge capacity (Qcell) per unit weight of the total active material in the cathode and anode. The obtained values were compared with the calculated values, which were determined by analyzing the temperature and capacity coefficients of the redox potential.

1427 9046

Open Access Research Article

The Lived Experience of Individuals with Chronic Traumatic Brain Injury: An Adapted Group Yoga Intervention

Received: 04 November 2018;  Published: 16 December 2018;  doi: 10.21926/obm.icm.1804033

Abstract

Background: An adapted yoga intervention was delivered to seven individuals with chronic traumatic brain injury. The purpose of this study was to explore and describe the participants' experience of engaging in the 8-week intervention. Methods: Using a phenomenological design, data were collected, analyzed, and coded to generate themes regarding experiences that occurred, how experiences occurred, and why experiences occurred. Results: Participants described experiencing the yoga intervention as a process: from ini [...]

1381 9044

Open Access Opinion

The Conundrum of High Body Mass Index in Kidney Transplant Patients

Received: 19 October 2018;  Published: 19 November 2018;  doi: 10.21926/obm.transplant.1804026

Abstract

Obesity is on the rise and the number of end stage renal disease patients who are obese parallel this trend. There is no universally accepted guideline for wait-listing end stage renal disease obese patients in order to reduce surgical complications and improve survival of the kidney graft. Criteria for acceptance are variable among transplant centres, as do post-transplant policies. Careful risk assessment to maximise the benefits of the limited organ donor resource must be undertaken prior to waitlist an obese ki [...]

1283 9042

Open Access Review

Molecular Marker Applications in the Selection of Elite Genotypes for Plant Stress Tolerance and Genetic Fidelity

Received: 17 May 2024;  Published: 02 September 2024;  doi: 10.21926/obm.genet.2403260

Abstract

Molecular markers play a crucial role in accelerating crop production for sustainable agriculture by identifying resistant traits and enhancing genetic diversity. In this review, we examine the impact of the molecular markers on advancing our understanding of stress tolerance mechanisms in plants, addressing the pressing imperative to bolster global food production to meet the escalating demands of the growing population. Additionally, the application of molecular markers to evaluate the genetic accuracy of plants [...]

1214 9041

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