by Gerhard Litscher

Received: 27 May 2016;  Published: 15 August 2016;  doi: 10.21926/obm.icm.1601001

Integrative and Complementary Medicine (ICM-OBM) is an international peer-reviewed, open-access journal which covers all evidence-based scientific studies on integrative and complementary approaches to improving health and quality of life. Integrative and complementary medicine comprises science-oriented “university” or academic medicine, but also experience-based medicine with all its complementary methods. It is not a special field in itself, but a signal for an all-encompassing medicine, open-minded about the p [...]

by Siva Mahendran  , Paramit Chowdhury  , Ronan Breen  , Grainne d’Ancona  and Heather J. Milburn

Received: 14 August 2020;  Published: 08 March 2021;  doi: 10.21926/obm.transplant.2101137

Patients with chronic kidney disease (CKD) have an increased risk of developing tuberculosis (TB) compared to those with normal renal function. The reasons for this are well described, but include impaired cellular immunity, a high incidence of co-morbid conditions as well as the concomitant use of immunosuppressive medications. Ethnicity as well as socio-economic factors also prevail. Expert guidelines recommend TB chemoprophylaxis in renal transplant recipients deemed at high risk – invariably those from ethnic m [...]

by Vineela Nagamalla  , Jay Patel  and Mir Saleem

Received: 20 December 2020;  Published: 21 July 2021;  doi: 10.21926/obm.neurobiol.2103104

Alzheimer’s disease (AD) is a neurodegenerative condition which consists of stages of mental, memory, and cognitive decline. As it continues to stand as the sixth leading cause of death in the U.S., 44 million people worldwide are affected. The objective of this paper is to explore the risk factors for AD in an attempt to examine potential causes for the incidence of AD. We examined genetics, lifestyle, and pre-existing conditions as risk factors for AD. We found that there are various alleles, such as APP, P [...]

by Tina Huang  , Tony Hung  , S. Irene Kim  and Ka Kit Hui

Received: 07 October 2019;  Published: 02 March 2020;  doi: 10.21926/obm.icm.2001011

Acupuncture has increasingly been used to address a variety of symptoms in patients with cancer. Here we present a case to illustrate the use of acupuncture in a 35-year-old female with metastatic breast cancer who presented to the UCLA Center for East-West Medicine (CEWM) with physical and psychological symptom clusters of insomnia, anxiety, and joint pain.

by Sofia Silva  , Alexandra Cravo  , João Rodrigues  , Cátia Correia  and Cristina M.M. Almeida

Received: 09 April 2021;  Published: 19 June 2021;  doi: 10.21926/aeer.2102015

The use of biomarkers in bivalves has gained significance as a reliable method for the assessment of the presence and effect of contaminants in aquatic ecosystems. However, it is important to note that the biomarkers respond not only to contaminant loadings and bioavailability but also to environmental stress. Therefore, the association between biomarkers and contamination/pollution should be conducted cautiously as the environmental factors also affect their response. These factors should be integrated into the as [...]

by Joep Geraedts

Received: 05 June 2018;  Published: 23 July 2018;  doi: 10.21926/obm.genet.1803024

Both preimplantation genetic testing (PGT) and prenatal diagnosis (PND) are powerful tools to tackle the transmission of inherited disorders carried by families from generation to generation. Here, we present an overview of the current landscape of both methods and identify the pros and cons of each of these reproductive options. In prenatal testing, non-invasive diagnostic methods have become available as an alternative for invasive diagnosis. Different genome sequencing strategies have now been introduced that en [...]

by Owen Sedej  , Eric Mbonimpa  , Trevor Sleight  and Jeremy Slagley

Received: 18 February 2022;  Published: 18 August 2022;  doi: 10.21926/jept.2203027

Waste-to-Energy technologies have the potential to dramatically improve both the natural and human environment. One type of waste-to-energy technology that has been successful is gasification. There are numerous types of gasification processes and in order to drive understanding and the optimization of these systems, traditional approaches like computational fluid dynamics software have been utilized to model these systems. The modern advent of machine learning models has allowed for accurate and computationally ef [...]

by Razieh Sadraei

Received: 25 April 2020;  Published: 01 July 2020;  doi: 10.21926/rpm.2003017

A literature survey shows that the valorization of urban and/or agricultural biowastes into chemicals has caught the attention of experts and is gradually becoming quite an important issue. This review presents the application of the Bio-Based Substances (BBS) isolated from the compost of bio-wastes from urban gardening and park trimming residues. The non-cost BBS has been well studied in the literature. BBS are biological macromolecules with a complex lignin-derived structure containing several functional groups, [...]

by Arlene A. Schmid  , Marieke Van Puymbroeck  , Christine A. Fruhauf  , Laura A. Swink  and Jennifer D. Portz

Received: 29 September 2019;  Published: 25 November 2019;  doi: 10.21926/obm.geriatr.1904087

Background: Falls are relatively common in older adults and are associated with chronic pain. Chronic pain may even be a predictor of falls in older adults. However, this relationship has not been studied in adults

by Thaninee Prasoppokakorn  , Supachaya Sriphoosanaphan  , Nutbordee Nalinthassanai  , Thitaporn Roongrawee  , Pongtorn Hanboonkunupakarn  , Pisit Tangkijvanich  and Rungsun Rerknimitr

Received: 08 December 2023;  Published: 02 February 2024;  doi: 10.21926/obm.icm.2401013

Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022. The patients were randomized to receive a combination of Andrographolide and favipiravir or favipiravir monotherapy. The primary outcome was the occurrence rate of severe pneumonia. The se [...]