by Nour Hasan  , Ankita P. Desai  and Jignesh Dalal

Received: 12 November 2019;  Published: 04 February 2020;  doi: 10.21926/obm.transplant.2001098

Invasive fungal disease (IFD) is a significant contributor to morbidity and mortality in pediatric patients undergoing hematopoietic stem cell transplantation (HSCT). Early detection and timely initiation of antifungal therapy is important for improved outcome, but diagnosis remains difficult, especially when relying on conventional microbiology methods such as culture and microscopy. Data on the use of fungal biomarkers for screening and diagnosis of IFD in HSCT pediatric patients are limited, precluding the devel [...]

by Areen Omary  and Tameka Chambers

Received: 17 August 2021;  Published: 22 December 2021;  doi: 10.21926/obm.geriatr.2104185

The current study aimed to examine if sex can significantly predict risk for lifetime major depressive episodes among adults aged 65 and older with and without adjustment for covariate variables of race, education, marital status, health, and poverty. Secondary data was obtained from the National Survey on Drug Use and Health public-use data file to achieve study goals. The study participants were males and females aged 65 years or older. The unweighted sample included 3,969 adults aged 65 years or older, represent [...]

by Andre Cardim de Aguiar  and Soraya Giovanetti El-Deir

Received: 09 May 2022;  Published: 20 September 2022;  doi: 10.21926/aeer.2203034

The presence of shopping malls causes a social, economic, and environmental impact. The bibliometric analysis is a valuable method used to dentify published research papers, and understand historic information published in scientific journals. This method can be used to carry out qualitative and quantitative analyses of scientific production on a specific subject. This analytical method primarily focuses on analyzing the bibliometric study of the solid waste management method used in shopping malls. A small number [...]

by Mario D. Garrett

Received: 12 June 2019;  Published: 16 July 2019;  doi: 10.21926/obm.geriatr.1903063

Simplifying the cause of Alzheimer’s disease has lulled the public into believing that the search for a cure is within reach. The disease has captured the attention of researchers worldwide, catapulting the disease as the third most funded research interest (after cancer and HIV). But after a century of pharmacological failures in stopping or slowing the disease, there is a need to examine how the simplified cause evolved and to explore alternate approaches to understanding Alzheimer’s disease. Going beyond the nar [...]

by Pratima Pandey  , Narges Sadat Shamabadi  , Ewen McLean  and Omar Bagasra

Received: 28 August 2020;  Published: 07 May 2021;  doi: 10.21926/aeer.2102009

Normally we encounter a myriad of chemicals in our daily lives. Endocrine disrupting chemicals [EDCs] are ubiquitous in our environment and upon bodily entry many be stored in adipose tissue and, in pregnant woman, can reach the developing fetal brain, disrupting normal fetal brain development. EDC-induced aberrant levels of sex hormones can alter sexual dimorphism [i.e. degree of feminization or masculinization; sex differences in brain and behavior] and may contribute to the differential susceptibility of males a [...]

by Owen Sedej  , Eric Mbonimpa  , Trevor Sleight  and Jeremy Slagley

Received: 18 February 2022;  Published: 18 August 2022;  doi: 10.21926/jept.2203027

Waste-to-Energy technologies have the potential to dramatically improve both the natural and human environment. One type of waste-to-energy technology that has been successful is gasification. There are numerous types of gasification processes and in order to drive understanding and the optimization of these systems, traditional approaches like computational fluid dynamics software have been utilized to model these systems. The modern advent of machine learning models has allowed for accurate and computationally ef [...]

by Rebecca H. Affoo  and Ashwini Namasivayam-MacDonald

Received: 06 August 2024;  Published: 09 December 2024;  doi: 10.21926/obm.geriatr.2404291

A conceptual model was developed to create a basis for understanding the risk factors and outcomes associated with dysphagia and to hypothesize the nature of the relationship between certain factors. The conceptual model was developed by two academic speech-language pathologists with ≥10 years research and clinical experience in swallowing and dysphagia in older adults. A comprehensive review of English-language literature was conducted, and relevant, evidence-informed factors associated with dysphagia in older adu [...]

by Catarina F. Martins  , Jorge Soares  and Maria Paula Mota

Received: 20 March 2024;  Published: 01 August 2024;  doi: 10.21926/obm.neurobiol.2403235

Alzheimer's disease is a neurodegenerative condition that impacts an individual's physical, cognitive, and social well-being, ultimately resulting in a decline in independence and functionality. This case report explores how a program combining multimodal physical exercise and psychomotor rehabilitation can improve outcomes in interventions for Alzheimer's disease patients. This approach can enhance treatment effectiveness and provide researchers and practitioners with additional therapeutic options. The participan [...]

by Sheila Krishnan  , Chadi Hage  , Raymond Coakley  , David van Duin  and Leonard Jason Lobo

Received: 18 February 2019;  Published: 10 June 2019;  doi: 10.21926/obm.transplant.1902065

Lung transplant recipients are at greater risk of respiratory viral infections as compared to other solid organ transplant recipients due to constant exposure of the allograft to the external environment. There are no standardized methods for surveillance, prevention, or treatment of these infections despite their association with increased morbidity and mortality. Various studies have linked respiratory viral infections with acute cellular rejection and chronic allograft dysfunction, and emerging data indicates a [...]

by Thaninee Prasoppokakorn  , Supachaya Sriphoosanaphan  , Nutbordee Nalinthassanai  , Thitaporn Roongrawee  , Pongtorn Hanboonkunupakarn  , Pisit Tangkijvanich  and Rungsun Rerknimitr

Received: 08 December 2023;  Published: 02 February 2024;  doi: 10.21926/obm.icm.2401013

Reports indicate that Andrographolide inhibits viral replication and reduces COVID-19 symptoms. This study aimed to determine Andrographolide's additional effect and safety in mild COVID-19 patients treated with favipiravir. A multicenter, open-labeled, randomized controlled trial was conducted from October 2021 to February 2022. The patients were randomized to receive a combination of Andrographolide and favipiravir or favipiravir monotherapy. The primary outcome was the occurrence rate of severe pneumonia. The se [...]