by Spiros Koutandos

Received: 21 October 2023;  Published: 07 February 2024;  doi: 10.21926/rpm.2401005

In this paper, we continue our previous work by discussing the consequences of curvature in spacetime caused by the presence of mass and the implications of this. We address the question raised by Dirac regarding the impact of a magnetic monopole on the quantum world. We discuss quantization concerning the solid angles observed, which may have a connection with a magnetic monopole.

by Christine Demanche  , Jacques Guillot  and Magali Chabé

Received: 22 February 2019;  Published: 15 May 2019;  doi: 10.21926/obm.genet.1902078

Pneumocystis spp. are a group of fungi that are known for causing opportunistic infections in immunocompromised individuals. It was only at the end of the 20th century that the scientific community challenged the notion of a unique species in the genus Pneumocystis (i.e., Pneumocystis carinii) that drastically changed the understanding of the natural history of pneumocystosis. It is now accepted that the Pneumocystis genus comprises a group of heterogenous fungi having multiple stenoxenic biological entities. These [...]

by Waqar Husain  , Farrukh Ijaz  , Muhammad Ahmad Husain  , Marwa Zulfiqar  and Javeria Khalique

Received: 20 December 2023;  Published: 23 January 2024;  doi: 10.21926/obm.icm.2401011

The assessment of mental health and mental disorders has undergone extensive exploration within the field of psychology, resulting in various models and approaches. In addition to traditional ways like the Diagnostic and Statistical Manual of Mental Disorders, psychologists have proposed alternative perspectives for evaluating mental health. One such innovative approach is the psychosocial health model, which defines mental well-being as sexual, emotional, social, environmental, cognitive, religious, moral, and spi [...]

by Francesco Sciancalepore  , Giulia Remoli  , Leonardo Tariciotti  , Giulia Sarti  , Federica Trentin  , Gabriele Riccardi  , Eleonora Lacorte  , Massimo Corbo  , Marco Canevelli  , Nicola Vanacore  and Paola Piscopo

Received: 05 February 2021;  Published: 19 May 2021;  doi: 10.21926/obm.neurobiol.2102097

Deep-Brain Stimulation (DBS) is an important treatment option for the management of Parkinson’s disease (PD) and is a common symptomatic treatment. However, an increasing number of studies have examined the biological processes to assess if DBS can also modify the natural history of PD by acting on its pathophysiological mechanisms. Relevant literature published up to November 2020 was systematically searched on databases such as PubMed, ISI Web of Knowledge, Academic Search Index, and Science Citation Index. The f [...]

by Nuria Arias-Ramos  , Jesús Pacheco-Torres  and Pilar López-Larrubia

Received: 11 November 2018;  Published: 30 January 2019;  doi: 10.21926/obm.neurobiol.1901020

Background: Despite important advances in multimodal therapeutic options, glioblastoma (GBM), the most frequent and aggressive form of all astrocytomas, remains with a median overall survival period of 15 months. A direct correlation between GBM hypoxia and higher aggressiveness, poor prognosis and greater resistance to different treatments has been established. However, because of intratumoral and interindividual heterogeneity, it has not been possible to assess accurately the hypoxia degree from physiopathologica [...]

by Berta Monleón López  , Valentina Della Torre  , Federico Bilotta  and Rafael Badenes

Received: 11 June 2019;  Published: 22 August 2019;  doi: 10.21926/obm.neurobiol.1903037

Purpose of review: The purpose of this review is to describe recent evidence regarding the use of Extracorporeal Membrane Oxygenation (ECMO) as rescue therapy for refractory cardiac or respiratory failure in patients with traumatic brain injury (TBI) when conventional treatments have failed. The characteristics of these patients, including the risk of bleeding and developing malignant intracranial hypertension, are generally considered as relative contraindications to ECMO treatment; however, recent evidence sugges [...]

by Hamid Ullah  , Sara Iqbal  , Blanca Lizaola Mayo  and Elizabeth Carey

Received: 31 March 2021;  Published: 20 July 2021;  doi: 10.21926/obm.transplant.2103149

Liver transplantation (LT) has grown monumentally in the last 40 years. Sarcopenia has emerged as an independent factor associated with increased mortality in patients with end stage liver disease. In this review we aim to shed light upon recent developments in assessment, clinical implications, management of sarcopenia in patients requiring a liver transplant. We also bring attention to the impact of COVID-19 pandemic on sarcopenia which ranges from the disease pathology to the unprecedented preventive measures ta [...]

by Oghenerume Lucky Emakpor  , Great Iruoghene Edo  , Emad Yousif  , Princess Oghenekeno Samuel  , Agatha Ngukuran Jikah  , Khalid Zainulabdeen  , Athraa Abdulameer Mohammed  , Winifred Ndudi  , Susan Chinedu Nwachukwu  , Ufuoma Ugbune  , Joy Johnson Agbo  , Irene Ebosereme Ainyanbhor  , Huzaifa Umar  , Helen Avuokerie Ekokotu  , Ephraim Evi Alex Oghroro  , Patrick Othuke Akpoghelie  , Joseph Oghenewogaga Owheruo  , Lauretta Dohwodakpo Ekpekpo  , Priscillia Nkem Onyibe  , Ufuoma Augustina Igbukuc  , Endurance Fegor Isojec  and Arthur Efeoghene Athan Essaghahk

Received: 28 December 2023;  Published: 28 June 2024;  doi: 10.21926/obm.icm.2402038

The optimal enhancement of athletic performance, recovery from exhaustion after exercise, and injury prevention are products of appropriate nutrition. Nutritional supplements that contain proteins, carbohydrates, vitamins, and minerals are frequently utilized in various sports to complement the recommended daily amounts. Several of these supplements have been identified to have physiological effects and, thus, are known to help enhance athletic performance and prevent injuries. Our review intends to show the interp [...]

by Fathi M. Layas  , Vail Karakale  and Ramadan E. Suleiman

Received: 28 April 2023;  Published: 27 July 2023;  doi: 10.21926/rpm.2303029

In recent years, regional wars and terror activities have caused blast-loading effects on reinforced concrete buildings, resulting in catastrophic human and material damage. When a building is exposed to a blast load, a very high air pressure affects the building within a very short duration. To decide on the reconstruction or retrofit of a building exposed to blast loading, the behavior of the building under blast loading should be investigated. In this paper a case study of a RC building exposed to blast loading [...]

by Sunil Daga  , Adarsh Babu  , Natasha Khovanova  and Robert Higgins

Received: 11 May 2021;  Published: 17 August 2021;  doi: 10.21926/obm.transplant.2103151

Antibodies against donor HLA determine access to solid organ transplantation and in many cases the outcome of transplantation, but graft failure is not an inevitable consequence of their presence. Much research has been performed with two main aims – which antibodies represent the highest risk factor prior to transplantation, and second to understand how donor specific HLA antibodies behave after transplantation, with a long-term aim of being able to manipulate their production. HLA antibody incompatible kidney tra [...]