by Victoria S. Jiminez  , Minh Chung  , Mohammad Saleem  and Nabiha Yusuf

Received: 02 July 2022;  Published: 17 April 2023;  doi: 10.21926/obm.geriatr.2302233

Skin aging is a complex process that involves several extrinsic and intrinsic factors and skin health is an indicator of the well-being of an individual. In recent years, there have been numerous developments using computerized systems to aid in finding solutions and treatments to skin aging processes. Tools like artificial intelligence (AI) can aid in finding solutions and treatments for skin aging. AI can also help in monitoring or identifying early signs of skin aging. Within the field of skin aging, several inn [...]

by Giacinto Libertini

Received: 19 February 2017;  Published: 13 April 2017;  doi: 10.21926/obm.geriatr.1702002

Currently, geriatric medicine consists mainly of palliative treatment of the disorders that characterize senile decay. This is perfectly compatible with the prevailing view that aging is the inevitable result of multiple degenerative processes that cannot be treated effectively as they are, in themselves, inevitable and irreversible. This interpretation of aging clashes with a mass of data and arguments that, conversely, indicate that aging is a specific physiological function, favoured by supra-individual natural [...]

by Francesco Sciancalepore  , Giulia Remoli  , Leonardo Tariciotti  , Giulia Sarti  , Federica Trentin  , Gabriele Riccardi  , Eleonora Lacorte  , Massimo Corbo  , Marco Canevelli  , Nicola Vanacore  and Paola Piscopo

Received: 05 February 2021;  Published: 19 May 2021;  doi: 10.21926/obm.neurobiol.2102097

Deep-Brain Stimulation (DBS) is an important treatment option for the management of Parkinson’s disease (PD) and is a common symptomatic treatment. However, an increasing number of studies have examined the biological processes to assess if DBS can also modify the natural history of PD by acting on its pathophysiological mechanisms. Relevant literature published up to November 2020 was systematically searched on databases such as PubMed, ISI Web of Knowledge, Academic Search Index, and Science Citation Index. The f [...]

by Donatella Ciarmoli  and Fabrizio Stasolla

Received: 04 September 2022;  Published: 13 March 2023;  doi: 10.21926/obm.neurobiol.2301163

Neurodevelopmental disorders represent a cluster of conditions first diagnosed during childhood or adolescence (i.e., including intellectual disability, autism spectrum disorders, motor deficits, and communication deficits). The main characteristic of neurodevelopmental disorders is the presence of a deficit or a delay in the acquisition of skills that may affect different areas of evolution (e.g., cognitive, affective, and motor). These clinical conditions make the child or adolescent passive, isolated, and unable [...]

by Barbara L. Fischer  , Allison J. Midden  , Aundrea Hoffmann  , Deborah Urben  , Lynn DeWitt  , Kathryne Kohlman  , Katherine Sherman  , Shannon Myers  , Lindy Clemson  and Jane E. Mahoney

Received: 14 September 2020;  Published: 08 January 2021;  doi: 10.21926/obm.geriatr.2101151

Cognitive impairment significantly increases the risk of accidental falls in older adults, and falls outcomes are more severe in this population. However, few interventions exist to reduce falls among individuals with cognitive impairment. To address this gap, we developed Stepping Out, by modifying the evidenced-based falls prevention program, Stepping On, tailoring it to meet the cognitive needs of individuals with mild cognitive impairment (MCI) who are at risk for falls. Our objectives were to determine whether [...]

by Barbara Schmidt  , Teresa Deffner  and Jenny Rosendahl

Received: 11 December 2019;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002025

Patients in the intensive care unit are confronted with an extreme situation that may cause stress and anxiety. The negative experiences may cause patients to suffer for the long-term after leaving the intensive care unit. One such stressor in the intensive care unit is non-invasive ventilation. Positive therapeutic suggestions under hypnosis can help patients in intensive care to enhance their well-being by helping them to deal with specific stress like being ventilated. The aim of our study is to assess the effec [...]

by Caroline Soares  and Paula Ministro

Received: 04 January 2024;  Published: 19 March 2024;  doi: 10.21926/rpn.2401003

Inflammatory bowel diseases (IBD) affect primarily the bowel, but they are multisystemic diseases with a wide range of extraintestinal manifestations and complications. Nutritional imbalance occurs frequently in patients with IBD. The spectrum of malnutrition goes from undernutrition (low protein-caloric intake, disease-related malnutrition, micronutrient deficiencies) to overnutrition and obesity. The nutritional status of patients with IBD is increasingly recognized as a key aspect of the treatment and must be ad [...]

by Kristin Drexler  and Ed Boles

Received: 02 March 2024;  Published: 25 July 2024;  doi: 10.21926/aeer.2403017

Watershed health and integrity are essential to human and ecosystem health and well-being. New River watershed communities in northern Belize, Central America are vulnerable to annual ‘cultural eutrophication’ - natural eutrophication exacerbated by human activity. Human-caused pollution from agriculture, septic effluent, and industrial drainage, in combination with extended drought and the slow flow of New River, has caused more frequent and prolonged periods of eutrophication. In this qualitative study, 42 New Ri [...]

by Sunil Daga  , Adarsh Babu  , Natasha Khovanova  and Robert Higgins

Received: 11 May 2021;  Published: 17 August 2021;  doi: 10.21926/obm.transplant.2103151

Antibodies against donor HLA determine access to solid organ transplantation and in many cases the outcome of transplantation, but graft failure is not an inevitable consequence of their presence. Much research has been performed with two main aims – which antibodies represent the highest risk factor prior to transplantation, and second to understand how donor specific HLA antibodies behave after transplantation, with a long-term aim of being able to manipulate their production. HLA antibody incompatible kidney tra [...]

by Berta Monleón López  , Valentina Della Torre  , Federico Bilotta  and Rafael Badenes

Received: 11 June 2019;  Published: 22 August 2019;  doi: 10.21926/obm.neurobiol.1903037

Purpose of review: The purpose of this review is to describe recent evidence regarding the use of Extracorporeal Membrane Oxygenation (ECMO) as rescue therapy for refractory cardiac or respiratory failure in patients with traumatic brain injury (TBI) when conventional treatments have failed. The characteristics of these patients, including the risk of bleeding and developing malignant intracranial hypertension, are generally considered as relative contraindications to ECMO treatment; however, recent evidence sugges [...]