by Em V. Adams  , Marieke Van Puymbroeck  , Brent L. Hawkins  and Arlene A. Schmid

Received: 19 August 2020;  Published: 22 December 2020;  doi: 10.21926/obm.geriatr.2004144

Using a qualitative approach, this study explored the perceived impacts of a therapeutic yoga intervention for individuals with Parkinson’s disease (PD), and examined the beneficial components of the intervention. Eighteen individuals with PD who completed an eight-week yoga intervention participated in focus groups to determine the general effects, transference of effects, and psychosocial impact of the intervention. Additionally, programmatic aspects of the intervention were explored. A conventional content analy [...]

by Maathar Al Qasimi  , Dhafer Manna Al Zulayqa  and Mostafa Seifan

Received: 29 July 2020;  Published: 23 October 2020;  doi: 10.21926/rpm.2004022

Additive manufacturing is a recent revolution in the construction field since cementitious materials became printable. This extrusion technique has enabled the construction of very complex geometry with a reduction in costs, time and labour interventions. This study aims to evaluate the possibility of reinforcing 3D printable cementitious composites with the use of nano and micro materials, particularly nano silica, micro silica and microfibrillated cellulose (MFC) which are known for their ability to enhance the f [...]

by Elena Crooks  and Kimberly Cleary

Received: 14 September 2019;  Published: 25 October 2019;  doi: 10.21926/obm.geriatr.1904082

Background: Falls are the leading cause of hospitalization and death among older adults; therefore, the ability to predict fall risk among older adults is critical. Several performance-based outcome measures exist to assess fall risk. Psychological factors are also associated with fall risk yet can be difficult to assess and are often overlooked. In this study, we investigated whether the Short Form 36 Item Health Survey (SF-36v2®), a measure of health-related quality of life (HRQOL), predicted future falls in [...]

by Carly M. Darden  , Srividya Vasu  , Kenjiro Kumano  , Bashoo Naziruddin  and Michael C. Lawrence

Received: 21 November 2018;  Published: 29 January 2019;  doi: 10.21926/obm.transplant.1901043

Islet transplantation is a minimally invasive cell based replacement therapy to prevent or reverse diabetes or hypoglycemia through natural hormonal responses to regulate blood glucose. However, extending the islet graft functional lifespan remains a challenge that prevents long-term success and widespread use of the procedure. Islets are subject to stress and damage and undergo immunological assault during transplantation procedures. Current treatments to prevent immune reactivity toward the graft come with toxic [...]

by Donatella Ciarmoli  and Fabrizio Stasolla

Received: 04 September 2022;  Published: 13 March 2023;  doi: 10.21926/obm.neurobiol.2301163

Neurodevelopmental disorders represent a cluster of conditions first diagnosed during childhood or adolescence (i.e., including intellectual disability, autism spectrum disorders, motor deficits, and communication deficits). The main characteristic of neurodevelopmental disorders is the presence of a deficit or a delay in the acquisition of skills that may affect different areas of evolution (e.g., cognitive, affective, and motor). These clinical conditions make the child or adolescent passive, isolated, and unable [...]

by Xi Chen  and Jianhua Xuan

Received: 19 October 2019;  Published: 07 April 2020;  doi: 10.21926/obm.genet.2002107

The analysis of gene networks and signalling pathways plays a key role in understanding gene functions, i.e., their effects on the development of a particular disease. Yet, for many heterogeneous diseases, the number of known disease-associated genes is limited. Identifying disease-associated genes is still an open challenge. To understand the functions of genes associated with a disease, we develop a Metropolis-Hastings sampling based SIGnificant NETwork (MSIGNET) identification approach. MSIGNET integrates diseas [...]

by Mohammad Jafari  and Zahra Malekjamshidi

Received: 13 June 2020;  Published: 05 August 2020;  doi: 10.21926/jept.2003014

In this paper, a topology of a residential hybrid renewable energy system based on a high-frequency multi-winding transformer is introduced and analyzed. The system includes a PV and a wind-turbine as renewable energy sources, a battery as energy storage and their energies are integrated through a high-frequency transformer. In fact, the transformer integrates the energies in a magnetic form and also isolates the system inputs and outputs. The integrated output from renewables and battery is a DC high-voltage and i [...]

by Barbara L. Fischer  , Allison J. Midden  , Aundrea Hoffmann  , Deborah Urben  , Lynn DeWitt  , Kathryne Kohlman  , Katherine Sherman  , Shannon Myers  , Lindy Clemson  and Jane E. Mahoney

Received: 14 September 2020;  Published: 08 January 2021;  doi: 10.21926/obm.geriatr.2101151

Cognitive impairment significantly increases the risk of accidental falls in older adults, and falls outcomes are more severe in this population. However, few interventions exist to reduce falls among individuals with cognitive impairment. To address this gap, we developed Stepping Out, by modifying the evidenced-based falls prevention program, Stepping On, tailoring it to meet the cognitive needs of individuals with mild cognitive impairment (MCI) who are at risk for falls. Our objectives were to determine whether [...]

by Ugo Testa  , Germana Castelli  and Elvira Pelosi

Received: 27 May 2020;  Published: 06 August 2020;  doi: 10.21926/obm.genet.2003114

Cancer is characterized by sequential and progressive genetic and epigenetic alterations in key proto-oncogenes and tumor suppressor genes, which ultimately lead to tumor development. Advances in the technology of analysis of molecular mechanisms have increased the efficiency of clinical management of cancer patients. Recent years have witnessed a progressive development in technologies that enable the detection of specific molecular abnormalities associated with various types of solid tumors in body fluids, a proc [...]

by Nadia A. Abdelmegeed Abdelwahed

Received: 19 September 2023;  Published: 04 January 2024;  doi: 10.21926/obm.neurobiol.2401205

Entrepreneurial intention plays a pivotal role within entrepreneurship ecosystems, acting as a catalyst for economic growth and innovation by inspiring individuals to embrace entrepreneurship as a viable career pursuit. The present research delves into the intricate dynamics between stress, entrepreneurial intention, personal income, and physical health within Egypt's entrepreneurial landscape. Grounded in a quantitative analysis of 286 valid samples and utilizing SmartPLS 4, this study unveils compelling insights. [...]