Table of Content

Open Access Review

Pancreatic Islet Cell Transplantation: Graft Stability and Metabolic Outcomes

Received: 07 June 2020;  Published: 07 July 2020;  doi: 10.21926/obm.transplant.2003115

Abstract

Pancreatic islet transplantation is a rapidly evolving field. It has been increasingly regarded as a promising approach for the correction of dysglycemia associated with type 1 diabetes mellitus (allogenic islet transplantation), or the prevention of surgical diabetes in chronic pancreatitis subjects undergoing total pancreatectomy (autologous islet transplantation). In this review, we discuss the latest literature pertaining to metabolic outcomes of autologous and allogenic islet transplantation, shedding close li [...]

2269 11907

Open Access Research Article

Morpholine-Based Novel Ionic Liquid for Synthesis and Characterization of Triazolidinethiones and Their Biological Properties

Received: 03 December 2022;  Published: 12 March 2023;  doi: 10.21926/cr.2301011

Abstract

Keeping the green chemistry approach in mind we have synthesized a novel morpholine-based ionic liquid [NBMMorph]+Br-. The structure of Ionic liquid was confirmed by spectral techniques viz. IR, 1H NMR, and 13C NMR, analysis. The synthesized novel IL [NBMMorph]+Br- was utilized to prepare 1,2,4-triazolidine-3-thiones of biological significance. The [NBMMorph]+Br- IL shows excellent catalytic activity, and a simple filtration technique can separate the thiazolidinedione products. The structure of the synthesized com [...]

2157 11899

Open Access Original Research

Wind-Stress Variations from Deep to Shallow Water during Hurricanes for Air-Sea-Land Interaction Applications

Received: 27 December 2021;  Published: 14 February 2022;  doi: 10.21926/aeer.2201006

Abstract

In September 2020 Hurricane Sally impacted two National Data Buoy Center (www.ndbc.noaa.gov) buoys near its track: 42040 in the deep water and 42012 in the shallow. Using pertinent air-sea interaction formulas from the literature, analyses of these buoy data indicate that, under fully rough airflow and wind sea conditions, U* = a Hs2 /Tp3 + b, here U* is the friction velocity, Hs is the significant wave height, and Tp is the peak wave period. It is found that a = 28 and b = 0.12 for the deep water environment, a = [...]

1511 11895

Open Access Short Report

Compassion-Focused Therapy and People with Intellectual Disabilities: A Renewed Focus

Received: 06 March 2022;  Published: 04 January 2023;  doi: 10.21926/obm.icm.2301002

Abstract

Compassion-Focused Therapy is an integrative therapeutic model with a wealth of evidence behind its efficacy. Its accessibility leads it to be a helpful therapeutic modality for the intellectual disability population. Its ability to aid the understanding of the person, us as clinicians, and the wider context around us give a depth of understanding not prioritised across all therapeutic models. This article explores Compassion-Focused Therapy in the context of working alongside people with intellectual disabilities. [...]

1786 11894

Open Access Research Article

Effects of Chemical Stabilisation of Eggshells-Lime and Fly-Ash-Cement on the Structural Strength of Subgrade Soil in Rural Roads

Received: 15 May 2022;  Published: 04 August 2022;  doi: 10.21926/rpm.2203013

Abstract

This study examines the chemical compositions of eggshell powder (ESP) and lime as the soil stabilisers and compared with the compositions of cement and fly-ash to understand the optimal distribution of chemical stabilisers maximising the bearing capacity and structural integrity of subgrade soil. The different proportions of eggshell powder (ESP) (2%, 4%, 6% and 8% of total soil mass) were mixed with a fixed proportion of lime (6% of total soil mass) to analyse the optimum proportion of eggshell maximising the soi [...]

1499 11888

Open Access Editorial

Hypnosis: From Neural Mechanisms to Clinical Practice

Received: 25 August 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003039

2499 11884

Open Access Concept Paper

German Guidelines for Molecular Genetic Diagnostic Testing Using High-throughput Technology, Such As Next-Generation Sequencing

Received: 24 September 2017;  Published: 28 April 2018;  doi: 10.21926/obm.genet.1802019

Abstract

On behalf of the German Society of Human Genetics, we present guidelines for molecular genetic diagnostic testing using high-throughput technology, such as next-generation sequencing (NGS). These guidelines have been formulated by an expert group and reviewed by members of the German Society of Human Genetics. Building on the existing EuroGentest guidelines for diagnostic NGS, these updated guidelines incorporate additional aspects and country-specific topics. New considerations include the introduction of a check [...]

2382 11867

Open Access Case Report

Candida auris and Heart Transplantation. Preoperative Attitude.

Received: 15 October 2018;  Published: 27 February 2019;  doi: 10.21926/obm.transplant.1901053

Abstract

In recent years, several agencies have issued warnings about the spread of Candida auris infections, a multidrug-resistant yeast that is associated with serious infections and with a mortality rate that can reach 70%. This problem is especially serious in transplant recipients receiving intense immunosupressive therapy. There are no established criteria on the relevance of this colonization or on when the transplant should be contraindicated in these cases. Five cases of colonization and two of candidemia have been [...]

1992 11864

Open Access Case Report

A Case of Coincidental Association of Amyotrophic Lateral Sclerosis in a Patient with Celiac Disease Consuming a Gluten-Free Diet

Received: 30 June 2020;  Published: 12 October 2020;  doi: 10.21926/obm.neurobiol.2004073

Abstract

We report, for the first time, the case of amyotrophic lateral sclerosis (ALS) onset in a 54-year-old woman not following a strict gluten-free diet (GFD) for six years after the diagnosis of celiac disease (CD). The patient did not display any sign of gluten toxicity, malabsorption, or CD-related comorbidity. Previous cases reported in medical literature showed ALS-like forms secondary to gluten intolerance, with symptom remission after a strict GFD. Even after correcting dietary flaws, the clinical manifestation o [...]

1954 11857

Open Access Original Research

Design and Techno-Economic Evaluation of a Hybrid Mini-grid System for an Academic Institution

Received: 26 September 2023;  Published: 03 April 2024;  doi: 10.21926/jept.2402010

Abstract

Inadequate electricity supply is a global challenge that needs solutions. This situation has compelled the purchasing of fossil fuel-generating units for use in residential, commercial, and industrial sectors to generate electricity. However, using fossil fuel generating units cause greenhouse gas emissions, bringing about environmental pollution and ultimately resulting in climate change. In particular, educational institutions require adequate and reliable power supply to ensure proper learning and teaching, whic [...]

2001 11856

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