by Leonard A. Jason

Received: 15 October 2024;  Published: 05 February 2025;  doi: 10.21926/obm.neurobiol.2501267

Following mental or physical exertion, patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) experience Post-Exertional Malaise (PEM). Although self-report questions represent less expensive and invasive procedures to assess PEM, variability in the wording of the symptom can cause reliability and validity problems. If different PEM measures are used in studies, this could create difficulties in replicating findings, identifying biomarkers, and determining effective treatments for patients. The o [...]

by Heidrun Männle  , Birthe Osorio  and Karsten Münstedt

Received: 09 March 2020;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002024

Palliative care is a steadily growing component of medicine that focuses on treating individuals with life-limiting diseases such as cancer. It aims at improving the quality of life and alleviating cancer-related symptoms, including anxiety, pain, dyspnea, cough, nausea/vomiting, and constipation, which could result in significant physical and mental impairment. Integrative palliative care (IPC), as a subspecialty of palliative care, includes complementary approaches to treat patients holistically in their biopsych [...]

by Pluvinage Guy  and Capelle Julien

Received: 03 March 2022;  Published: 01 September 2022;  doi: 10.21926/jept.2203029

Hydrogen is a dangerous gas due to its low ignition energy, wide flammability range, promotion of the embrittlement of steel, and its high coefficient of permeation for polymers. The fracture toughness and failure elongation of pipe steels are strongly impacted by hydrogen embrittlement, whereas yield stress and ultimate strength are moderately impacted. Specific tools are required for the pipe defect assessment used for the transport of hydrogen, which is pure or blended with natural gas. The safety factors associ [...]

by Brooks M. Hybertson  , Bifeng Gao  and Joe M. McCord

Received: 21 September 2021;  Published: 10 January 2022;  doi: 10.21926/obm.icm.2201002

There has been a long history of human usage of the biologically-active phytochemicals in Salvia rosmarinus, Zingiber officinale, and Sophora japonica for health purposes, and we recently reported on a combination of those plant materials as the PB123 dietary supplement. In the present work we extended those studies to evaluate activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor and differential gene expression in cultured HepG2 (hepatocellular carcinoma) cells treated with PB1 [...]

by JeongChul HEO  and Sumi HAN

Received: 15 June 2022;  Published: 08 October 2022;  doi: 10.21926/obm.neurobiol.2204141

This study aimed to verify whether self-directed learning readiness (SDLR) level can be significantly predicted by the literacy of learning management system (LLMS), motivation, and feedback interaction (FI) in non–face-to-face educational settings. We performed Pearson’s correlation analysis and multiple regression analysis. A total of 206 online college students responded to this web survey using simple random sampling. Results showed that three variables (LLMS, motivation, and FI) were positively associated with [...]

by Robert Resta

Received: 22 June 2021;  Published: 01 September 2021;  doi: 10.21926/obm.genet.2103136

The goals of prenatal testing remain controversial and reflect competing interests of public health, patient rights, disability activists, scholars, feminist critics, commercial laboratories, judiciary/legislative trends, and medical science. This paper reviews and critiques the most common justifications of prenatal testing for fetal aneuploidy that have been put forth over the half century of its existence: reducing the medical and economic burden to society of genetic disease through selective abortion, allowing [...]

by Niamh Flynn

Received: 18 March 2021;  Published: 02 May 2021;  doi: 10.21926/obm.neurobiol.2102092

Although studies to understand the pathogenesis of migraines are in progress, no theory has adequately explained the etiology and pathophysiology of migraines to date. This has affected the development of treatment strategies for migraineurs. Currently, the pharmacological treatment for migraines provides both acute and prophylactic options to patients based on a biomedical model of pain. However, patients’ adherence to oral migraine preventive medication (OMPM) is poor, and their persistence is even lower when the [...]

by Pietro Gareri

Received: 28 February 2022;  Published: 19 May 2022;  doi: 10.21926/obm.geriatr.2202198

The omega-3 long-chain polyunsaturated fatty acids (omega-3 LC-PUFAs) family includes eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and docosapentaenoic acid (DPA). Although seafood is the richest source of omega-3 LC-PUFAs, because diet alone is often insufficient in older people, they may require food supplements and enriched food as sources of omega-3 LC-PUFAs. It has been reported that long-term intake of 3-5 g/d EPA + DHA as supplements is safe for adults; omega-3 LC-PUFAs exert cardio-metabolic pro [...]

by Ana Pérez-González  and Ismael El Hajra

Received: 17 November 2024;  Published: 13 May 2025;  doi: 10.21926/rpn.2502010

In recent years, the incidence of Inflammatory Bowel Disease (IBD) has risen significantly in the Western population, pointing toward the potential influence of environmental and dietary factors. In order to explain this, some research on nutritional therapy identifies exclusive enteral nutrition (EEN) as a highly effective approach for managing IBD in children. This treatment achieves high remission rates; more specifically, some clinical trials have reported remission rates from 70% to 100%. EEN not only facilita [...]

by Uttayan Chakrabarti  , Manish Chaturvedy  , Nitin Kumar Bajpai  , Jitendra Goswami  , Rajesh Kumar Garsa  and Rajesh Jhorawat

Received: 10 April 2023;  Published: 14 July 2023;  doi: 10.21926/obm.transplant.2303192

BK virus (BKV) is a common opportunistic pathogen in kidney transplant recipients and one of the most challenging causes of allograft dysfunction and loss. Although over-immunosuppression remains the primary risk factor for BKV infection after transplantation, male gender, older recipient age, prior rejection episodes, degree of human leukocyte antigen mismatching, prolonged cold ischemia time, BK virus serostatus and ureteral stent placement have all been implicated as risk factors. Routine screening post-renal tr [...]

by Aurélie Laborel-Préneron  , Paulina Faria  , Jean-Emmanuel Aubert  and Camille Magniont

Received: 12 March 2021;  Published: 07 May 2021;  doi: 10.21926/rpm.2102016

Bio-based earth composites present various environmental benefits, such as usable wastes, coproducts, abundant or renewable materials, etc. Moreover, the incorporation of bioaggregates in the earth matrix allows the buildings to act as an effective carbon sink. A growing number of studies are now focusing on the mechanical and hygrothermal properties of bio-based earth building materials. However, the durability of these types of material is a major concern, and knowledge of their various aspects is essential to an [...]

by Adayabalam S. Balajee

Received: 26 August 2018;  Published: 19 October 2018;  doi: 10.21926/obm.genet.1804042

The technique of in situ hybridization (ISH) using radioactively labeled DNA probes was first described in the late 1960s and early 1970s. The first use of fluorescence in situ hybridization (FISH) was reported in 1980s where RNA labeled with a fluorophore at the 3’ end was used to detect specific DNA sequences. Since then, the technique has undergone various modifications for detecting single genes, chromosomes and whole genomes on various targets such as interphase nucleus, prematurely condensed chromosomes [...]

by Tracy Harwood  , John Maltby  and Elizabeta B. Mukaetova-Ladinska

Received: 28 March 2019;  Published: 15 July 2019;  doi: 10.21926/obm.geriatr.1903062

Background: Art enhances both physical and mental health wellbeing. The health benefits include reduction in blood pressure, heart rate, pain perception and briefer inpatient stays, as well as improvement of communication skills and self-esteem. In addition to these, people living with dementia benefit from reduction of their non-cognitive, behavioural changes, enhancement of their cognitive capacities and being socially active. Methods: The current study represents a narrative general literature review on availabl [...]

by Asaad G Ishak  , Sundar V Cherukuri  , GianCarlo Diaz  and Richard McCallum

Received: 25 January 2021;  Published: 02 July 2021;  doi: 10.21926/obm.geriatr.2103174

Dysphagia, or difficulty swallowing, is a common condition, especially among the elderly population and can become debilitating. As we age, there are subtle changes in esophageal motility, but by no means is dysphagia ever considered to be a normal result of aging. Dysphagia usually presents with a variety of accompanying symptoms ranging from regurgitation during meals, mild discomfort, to severe chest pain. It can be challenging to localize the dysphagia from the history. The underlying etiology may become eviden [...]

by Khalid Saidov  , Anna Tiunova  , Oksana Subach  , Fedor Subach  and Konstantin Anokhin

Received: 12 October 2018;  Published: 04 March 2019;  doi: 10.21926/obm.genet.1901065

Background: The method of cellular compartment analysis of temporal activity by fluorescent in situ hybridization (catFISH) is widely used in cellular and behavioral neurobiology. This technique exploits stimulus-induced expression of immediate early genes (IEGs) and allows identification of two neuronal populations activated in the brain of the same animal in response to neural or behavioral events separated by 25–30 min. The differential labeling is based on the visualization of nuclear RNA and cytoplasmic [...]

by Em V. Adams  , Brandi M. Crowe  , Jasmine Vanadore  , Marieke Van Puymbroeck  and Arlene A. Schmid

Received: 06 February 2022;  Published: 22 April 2022;  doi: 10.21926/obm.icm.2202020

The purpose of this descriptive survey was to explore how, and for what purpose, health care practitioners use yoga in clinical practice. A survey was administered to professionals who identified as healthcare practitioners who used yoga in their practice. There were 205 completed responses from a combination of healthcare practitioners including occupational therapists, physical therapists, yoga therapists, recreational therapists, speech-language pathologists, and mental health counselors. Practitioners worked in [...]

by Cathryn Duchette  , Danilo V Tolusso  , Whitley J Stone  , Maire M Blankenship  and Rachel A Tinius

Received: 23 June 2021;  Published: 25 November 2021;  doi: 10.21926/obm.icm.2104051

Studies have demonstrated that new and expectant mothers experience increased levels of stress and anxiety during the COVID-19 pandemic. Though prenatal yoga is an effective mode of improving mental health during pregnancy, no research has evaluated its effect on mental health during times of extreme stress, such as a global pandemic. The purpose of this study was to determine the influence of a single session and a 10-week prenatal yoga intervention on the mental health of pregnant women during the COVID-19 pandem [...]

by Ronald J. Pekala  and Kevin Creegan

Received: 20 January 2020;  Published: 13 April 2020;  doi: 10.21926/obm.icm.2002019

Noetic analysis is a methodology to quantify the mind during hypnosis, meditation, or other stimulus conditions/states of consciousness in a reliable and valid manner. The methodology uses retrospective phenomenological assessment (RPA) to comprehensively assess subjective experience. By having the participant complete a first person, self-report questionnaire, the Phenomenology of Consciousness Inventory (PCI), in reference to a short stimulus condition, the researcher can generate a “snapshot” of the mind, and it [...]

by Olorunjuwon O. Bello  , Rosemary O. Akande  , Temitope K. Bello  , Muibat O. Fashola  , Mathew O. Oni  and Adeleke Osho

Received: 21 July 2024;  Published: 20 January 2025;  doi: 10.21926/obm.icm.2501006

The incidence of antifungal-resistant pathogenic fungi has steadily increased around the globe and calls for an aggressive response. The study aimed to produce and evaluate virgin coconut oil's phytochemical properties and antifungal potentials (VCO). The production of VCO was achieved by hot extraction and natural fermentation methods. Gas Chromatography-Mass Spectrometry (GC-MS) was used to evaluate the active phytochemicals in the VCO. The antifungal activities of VCO against Aspergillus flavus, Aspergillus nige [...]

by Igor Val Danilov

Received: 09 May 2023;  Published: 02 November 2023;  doi: 10.21926/obm.neurobiol.2304192

The theoretical study observes literature to understand whether or not low-frequency oscillations can simultaneously alter the excitability of neurons from peripheral nervous subsystems in different individuals to provide Shared Intentionality in recipients (e.g., fetuses and newborns) and what are the attributes of ecological context for Shared Intentionality. To grasp the perception of objects during environmental learning at the onset of cognition, a fetus needs exogenous factors that could stimulate her nervous [...]

by Karen Harrison Dening  and Zena Aldridge

Received: 26 February 2019;  Published: 10 May 2019;  doi: 10.21926/obm.geriatr.1902053

There has been a strong thrust to identify the needs of people with dementia against a background of person-centred care, however, people with dementia do not exist in isolation; they live within relational contexts with family members. Case management is a model of care that has its origins in supporting patients with a long term disease, however, a very practical approach to case management that can support the care needs of both the person with dementia and the family carers is emerging in the UK. Admiral Nursin [...]

by Ernest Ilisca

Received: 18 June 2021;  Published: 29 October 2021;  doi: 10.21926/jept.2104045

Most of the hydrogen storage vessels meant for vehicles to run the electric motor via a fuel cell during transport are designed for drives of only a few tenths of kilometers per day. The present report, however, describes a vessel model that is conceived to hold the hydrogen energy only for short periods during transport, such as a few hours. This would include transport via a light-duty vehicle, a taxi, or a bus, which would load liquid hydrogen at a station every morning for the day. This is a simple model based [...]

by Preetam Datta  and Subhasis Roy

Received: 15 April 2023;  Published: 05 July 2023;  doi: 10.21926/cr.2303020

With increasing population levels and rapidly growing industries worldwide, the purification of water contaminated with different impurities is one of the biggest challenges we face in recent times. Photocatalysis holds great potential as an efficient mineralization process to remove the foreign matter present in wastewater. Rapid advancement in innovative materials development has made photocatalysis the frontrunner among different water treatment methods. Our main priority lies in different strategic approaches t [...]

by Gian Andrea Rollandi  , Aldo Chiesa  , Nicoletta Sacchi  , Mauro Castagnetta  , Matteo Puntoni  , Adriana Amaro  , Barbara Banelli  and Ulrich Pfeffer

Received: 31 January 2019;  Published: 05 May 2019;  doi: 10.21926/obm.geriatr.1902051

Aging is associated with an increased incidence of major diseases, including cancer, cardiovascular, neurodegenerative, metabolic and autoimmune diseases. Primary prevention and early diagnosis of these diseases have a dramatic impact on incidence, outcome, quality of life and are commonly applied as age-dependent indications based on evidence of efficacy for specific groups of the aging population. They likely contribute to the observed increase in life expectancy through the reduction of incidence and the retarda [...]

by Kelly Armstrong  , Raman Gokal  and Todd Todorsky

Received: 25 March 2019;  Published: 25 September 2019;  doi: 10.21926/obm.icm.1903056

Background: Direct Current (DC) micro-current point stimulation (MPS) is increasingly recognized as a therapy for chronic pain and stress management. However, there remains limited evidence as to the therapeutic value of MPS in chronic post surgical pain (CPSP) management related to C-Section scars. Objectives: We aimed to determine the effect and magnitude that MPS has when applied to C-section scars and its effects on a wide variety of non-specific chronic post surgical pain syndromes. Study Design: This was a co [...]