Aversion But Not Aggression: Emotional Traits of KM Rats in Sociability Tests
Abstract
386 1099
Aversion But Not Aggression: Emotional Traits of KM Rats in Sociability Testsby
Abstract
The inbred Krushinsky-Molodkina (KM) rat strain, characterized by latent genetic epilepsy, reduced social motivation, and a high propensity for freezing, is a promising model for translational research of social deficits in autism spectrum disorder (ASD). In clinical practice, social deficits often lead to social withdrawal and can be accompanied by aggression. It was unknown if KM rats exhibit such aggression during inescapable social encounters. We assessed intraspecific aggression in KM and control rats using th [...] 386 1099 |
Development of Methods for Transplanting Human Islet within Macroencapsulation Device that Reverse Diabetes in Miceby
Abstract
Transplanting islets into the subcutaneous (SC) space rather than the portal vein is advantageous because this site is easier and safer to use. However, transplantation of islets directly or within planar devices has been unsuccessful in humans, mainly because of the low oxygen torr in the SC space. Since human islets are very different from mouse islets, the use of human islets in animal experiments to study SC islet transplantation may help to alleviate the roadblocks of this approach in humans. This is the first [...] 270 1082 |
Acknowledgment to Reviewers of Recent Progress in Science and Engineering in 2025Abstract
The editors of Recent Progress in Science and Engineering would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2025. We greatly appreciate the contribution of expert reviewers, which is crucial to the journal's editorial process. We aim to recognize reviewer contributions through several mechanisms, of which the annual publication of reviewer names is one. Reviewers can download a certificate of recognition directly from our submission system. Additionally, reviewers [...] 435 1067 |
Central Post-Stroke Pain: Frequency, Clinical Characteristics, and Associated FactorsAbstract
Central post-stroke pain (CPSP) is a frequently underrecognized complication that contributes to long-term disability among stroke survivors. This study aimed to determine the frequency of CPSP and to describe its clinical characteristics and associated factors among stroke patients treated at Arifin Achmad General Hospital. A cross-sectional design was employed and included adult stroke patients with diagnoses confirmed by neuroimaging. CPSP was diagnosed based on the clinical criteria proposed by Klit et al., and [...] 222 1059 |
A New Model for the Shear of Atomic PlanesAbstract
The article presents a model that describes the shear of atomic planes in crystalline solids by accounting for their electronic structure. Previous studies have shown that an isotropic distribution of valence electrons leads to a spherically symmetric interatomic potential, which affects the stability of the crystal lattice against small shear deformations. Under these conditions, lattice stability is largely determined by the crystal's surface layer. As a consequence, the resistance to atomic-plane shear exhibits [...] 299 1025 |
The Impact of Governmental and Workplace Measures on the Employment Sustainability of Chronically Ill IndividualsAbstract
Using a two-stage qualitative design (Stage 1: expert interviews; Stage 2: biographical interviews with people with MS), existing governmental and organizational support measures for maintaining the work capacity of individuals with multiple sclerosis (MS) were analyzed, and proposals for improvement were developed. Additional state support measures were proposed, including relaxing the criteria for state assistance, creating a centralized contact point for MS-specific inquiries, and enhancing collaboration between [...] 400 1022 |
Examining the Pre-Hospital Workflow of Stroke Patients Referred with Code SAMA (724) and their Outcome in the Emergency Department of Imam Reza Hospital (AS)by
Abstract
The "Sama Code" is a protocol implemented in Iranian pre-hospital emergency services to manage time and treat patients with suspected stroke symptoms based on the FAST criteria. This study aims to analyze the workflow of patients with stroke symptoms transferred under the Sama Code. All patients with neurological symptoms who were brought to Imam Reza Hospital by pre-hospital emergency services after activating the Sama Code during the years 2021 and 2022 were included in the study. Data were collected from pre-hos [...] 339 1010 |
Stochastic Assessment of Renewable Energy Reliability: A Case Study of North Euboea, Greeceby
Abstract
The increasing penetration of renewable energy sources (RES) in the energy mix, particularly solar photovoltaic and wind power, poses significant challenges to electricity grid reliability due to their inherent stochastic variability. This study develops a stochastic framework to assess the ability of RES to balance electricity demand, with a focus on storage requirements and reliability implications. Using North Euboea, Greece, as a representative case study, normalized hourly time series of electricity demand, so [...] 237 969 |
The Prevalence of Autism in the World: An Umbrella Review and Meta-Analysisby
Abstract
Autism is a neurodevelopmental disorder characterized by persistent challenges in social interactions and repetitive behaviors. This study aimed to investigate the prevalence of autism and autism spectrum disorder(ASD) in normal and abnormal groups, such as premature infants or seizure patients, using an umbrella review and meta-analysis. This study was conducted in accordance with the PRISMA guidelines. Scientific sources included PubMed, Scopus, Web of Science, and Google Scholar, and searches were conducted with [...] 238 959 |
Evaluation of Ten Bread Wheat (Triticum aestivum) Cultivars and Five of Their Hybrids under Salinity Stress at Germination and Seedling Stageby
Abstract
Salinity poses a danger to food security; hence, it is necessary to create crop types that can withstand salt to meet the growing demand for food. The goal of the current study was to examine the morphological and biochemical responses of wheat (Triticum aestivum L.) genotypes under salt stress. Salt tolerance in ten wheat cultivars and five selected F1 hybrids was assessed at the germination and seedling stage. Genotypes were assessed for seven traits under control (0 mM NaCl) and salinity stress (150, 200, and 25 [...] 231 907 |
A Rapid Method of Examining Land Use/Land Cover at Small Industrial Facilities Using Four U.S. Department of Energy Sites as Case StudiesAbstract
This work addresses the application of a method to examine the spatial extent of ecological resources and green space on small Department of Energy (DOE) sites and comparison to ecological resources and green space in the surrounding region. Increasingly, governmental regulators, resource trustees, and the public are concerned that federal facilities are protecting human health and the environment, including ecological resources on their sites. This paper uses the National Land Cover/Land Use Database to examine an [...] 266 894 |
Sustainable and Environmentally Friendly Approaches for Eliminating Alizarin Red S from Contaminated Water Using Hydroxyfluorapatite-Based BiomaterialsAbstract
This study investigated the use of new bioadsorbent the Hydroxyfluorapatite (Ca10(PO4)6OH1.75F0.25, HFA) to eliminate Alizarin Red S (ARS), a harmful water pollutant. Initial batch tests were conducted to evaluate the adsorption process, focusing on both kinetics and equilibrium behavior. Various kinetic models were applied such as: pseudo first-order, pseudo second order, the intraparticular diffuision model and external diffusion model. The modeling results proved that the pseudo-second-order model best matched t [...] 285 846 |
Disability, Functional Limitations, and Family Violence among Older Adults in Brazil: A Cross-Sectional Study Using National Health Survey Data, Brazil 2019by
Abstract
Elder abuse is a global public health issue, with consequences on individual health, increased burden on healthcare systems, and high social costs. The study aimed to estimate the prevalence of family violence among older adults in Brazil and analyze its association with disability, comorbidities, functional limitation, and sociodemographic characteristics. Cross-sectional study using data from the 2019 National Health Survey (PNS 2019), including older adults aged 60 years or older. Bivariate and multiple logistic [...] 278 840 |
Determining the Role of KRAS in Patients with Different Demographic Profiles Diagnosed with Diabetes Mellitus: A Case-Control Studyby
Abstract
Diabetes mellitus (DM) is widely spread among populations. About 3 of 10 people show the symptoms of this disease. Many factors may cause this illness in both types (type 1 and type 2 DM), mainly attributed to insufficient insulin production in type 1 DM or developing insulin resistance in type 2 DM. Genes that control specific biochemical pathways involving glucose metabolism can interfere with the manifestation of this disease when they undergo genetic changes like KRAS. Investigating the role of KRAS in DM. Abou [...] 271 836 |
Athens 2026 – International Exchange of Professionals in Medicine: A Global Gala Technology Platform for Medical Sciences, Innovation, and Interdisciplinary CollaborationAbstract
The International Exchange of Professionals – Thematic Event in Medicine 2026, held in Athens, was a high-level interdisciplinary forum for clinical medicine, biomedical research, and translational innovation. Conducted at the Radisson Blu Park Hotel, the congress brought together more than 300 international experts from over 40 countries. It was organized under the auspices of the World High Technology Society in cooperation with BIT Group Global and the Shenzhen International Talent Exchange Center. The program i [...] 173 830 |
Assessment of Genetic Diversity and Polymorphism in Corylus avellana L. Pollen by Inter-Primer Binding Site Marker AnalysisAbstract
Genetically conditioned variation in pollen has been demonstrated to have a substantial influence on reproductive mechanisms and population dynamics. The present study evaluated the genetic variability of 28 pollen samples of Corylus avellana L. using iPBS (Inter Primer Binding Sites Polymorphism) markers 1882 and 2152. The collection of biological material was undertaken at various locations across five European countries, with the objective of capturing a broad spectrum of environmental conditions. The genetic re [...] 240 815 |
A Qualitative Exploration: Black Women Living with DepressionAbstract
Studies show Black women exhibit distinct depression symptoms and treatment experiences compared to other groups, often facing underdiagnosis and inadequate care. Unfortunately, knowledge about Black women with depression has been underexplored. Therefore, the purpose of this study is to gain a better understanding of Black women’s experiences living with clinical depression. To address this objective, we conducted a survey among 28 Black women aged 18 years and older (mean age = 35) residing in the United States, [...] 242 782 |
Complete Chloroplast Genome of Rauvolfia tetraphylla (Gentianales: Apocynaceae) and Phylogenetic AnalysisAbstract
Rauvolfia tetraphylla L. (1753) is an important medicinal species of Apocynaceae, widely used for its rich indole alkaloids and related bioactive compounds. We report the first complete chloroplast genome of R. tetraphylla. The genome exhibits a typical circular quadripartite structure of 155,667 bp, with an overall GC content of 37.8%. The genome comprises a large single-copy (LSC) region of 86,332 bp, a small single-copy (SSC) region of 17,853 bp, and a pair of inverted repeat (IR) regions of 25,741 bp each. A to [...] 241 732 |
Comprehensive Cytogenetic and ISSR Analysis in the Context of Conservation of the Local Breed of Brown Carpathian Cattle BreedAbstract
The article reveals the variability of the genome of cattle of the local small-numbered domestic Brown Carpathian breed using cytogenetic and molecular genetic polylocus markers, and justifies the need to integrate local breeds into the modern system of agricultural production in accordance with FAO requirements. The work aimed to study the genetic uniqueness of cows of the brown Carpathian breed using cytogenetic and molecular genetic markers. The karyotype of the animals corresponded to the species norm and was 2 [...] 187 722 |
Development of New Macroencapsulating Planar Devices to Inhibit Allorejection of Islet Transformed Cellsby
Abstract
Subcutaneous transplantation of islets into small-pore macroencapsulation devices that prevent immune cell passage can inhibit allorejection in rodents. However, there are no reports of euglycemia in humans using this technology. This report further develops these macroencapsulation devices. We compared the ability of macroencapsulation transplant devices containing transformed mouse islet cells (MIN-6) with varying polymer membranes, pore sizes, and hydrophilicity to inhibit allorejection and maintain glycemic con [...] 156 627 |
The Multi-Biophysical Nature of Computation in Brain Neural NetworksAbstract
Comprehending the nature of nerve communication is fundamental to our understanding of the functioning of nervous systems in general. The ionic mechanisms underlying action potentials in the squid giant axon were first described by Hodgkin and Huxley in 1952, and their findings have formed our orthodox view of how the physiological action potential functions. However, substantial evidence has now accumulated to show that the action potential is accompanied by a synchronized coupled soliton pressure pulse in the cel [...] 170 595 |
DWSIM-Based Process Simulation and Exergy Analysis of Bioethanol Production from Rice Huskby
Abstract
The growing concerns over fossil fuel dependency have motivated the exploration of sustainable biofuel alternatives. However, the practice of utilizing first-generation bioethanol production obtained majorly from food crops threat food supply market and poses threat to food security and land use. As a way forward, second-generation bioethanol from biomass, such as rice husk, an abundant agricultural residue, could potentially offer a promising pathway. Yet, its conversion remains energy-intensive and thermodynamica [...] 206 535 |
A Novel Missense Variant in the CDH23 Gene is Segregated in an Iranian Family with Hearing Lossby
Abstract
Sensorineural hearing loss (SNHL) describes a diverse group of clinically and genetically distinct disorders of the auditory system. SNHL is associated with mutations in up to 150 genes. Among them is Cadherin 23 (CDH23), which is associated with both Usher syndrome and non-syndromic hearing loss. In the current study, we used WES to find the genetic cause of SNHL in an extended Iranian family. WES and subsequent Sanger sequencing confirmed the occurrence of a novel homozygote variant in the CDH23 gene (c.817T>C, p [...] 135 523 |
A Case of Prenatal Diagnosis of Apert Syndrome in the Second Trimester of Pregnancyby
Abstract
Craniosynostosis is a disorder characterized by premature closure of cranial sutures, resulting in restricted skull growth perpendicular to the affected suture and compensatory growth in other directions. Over 180 syndromes have been classified under craniosynostosis, of which eight are associated with mutations in the fibroblast growth factor receptor 2 (FGFR2) gene: isolated coronal synostosis, Pfeiffer syndrome, Crouzon syndrome, Apert syndrome, Beare–Stevens syndrome, Jackson–Weiss syndrome, Crouzon syndrome wi [...] 153 522 |
Cr(VI) Adsorptive Removal Using Raw Cordia africana Sawdust: Optimization of Operating Parameters, Kinetics, Isotherm, Thermodynamics, and Desorption EfficiencyAbstract
Hexavalent chromium (Cr(VI)) is a carcinogenic pollutant commonly found in wastewater from tanning and electroplating industries. This study investigates the efficiency of raw Cordia africana sawdust as a biosorbent for Cr(VI) removal. Batch adsorption experiments were conducted by varying pH (3-8), contact time (10-120 min), and Cr(VI) concentration (21-47 mg/L) using Response Surface Methodology (RSM) with Box-Behnken design. Characterization was performed using FTIR, SEM, BET, pH, and PZC analysis before and aft [...] 158 484 |
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