by Nadezhda D Broshevitskaya  , Anastasia A Rebik  , Lidia M Birioukova  , Maria I. Zaichenko  and Inna S Midzyanovskaya

Received: 28 September 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601326

The inbred Krushinsky-Molodkina (KM) rat strain, characterized by latent genetic epilepsy, reduced social motivation, and a high propensity for freezing, is a promising model for translational research of social deficits in autism spectrum disorder (ASD). In clinical practice, social deficits often lead to social withdrawal and can be accompanied by aggression. It was unknown if KM rats exhibit such aggression during inescapable social encounters. We assessed intraspecific aggression in KM and control rats using th [...]

by Alireza Ala  , Samad Shams Vahdati  , Eliyar Sadeghi-Hokmabadi  , Sadaf Jalilzadeh  , Mahsa Kashtkar  and Asghar Jafari Rouhi

Received: 22 February 2025;  Published: 25 February 2026;  doi: 10.21926/obm.neurobiol.2601325

The "Sama Code" is a protocol implemented in Iranian pre-hospital emergency services to manage time and treat patients with suspected stroke symptoms based on the FAST criteria. This study aims to analyze the workflow of patients with stroke symptoms transferred under the Sama Code. All patients with neurological symptoms who were brought to Imam Reza Hospital by pre-hospital emergency services after activating the Sama Code during the years 2021 and 2022 were included in the study. Data were collected from pre-hos [...]

by Alisia Chen  and Jeong M. Park

Received: 29 October 2025;  Published: 24 February 2026;  doi: 10.21926/obm.transplant.2601267

Antibody mediated rejection (AMR) is a considerable cause of late allograft failure in solid organ transplantation. Conventional approaches, using plasmapheresis, intravenous immunoglobulin, rituximab, bortezomib, and eculizumab have been unsuccessful in improving graft survival. This review aims to assess emerging therapies for AMR treatment across all organs. Using a PubMed search, literature published up to July 20, 2025 regarding tocilizumab, clazakizumab, carfilzomib, daratumumab, imlifidase, felzartamab, and [...]

by Muhammad Hannan  , Muzafar Ali  , Chengpeng Lu  and Jia Xu

Received: 12 August 2025;  Published: 24 February 2026;  doi: 10.21926/aeer.2601004

Sindh Province, Pakistan, is highly vulnerable to hydroclimatic extremes, necessitating a detailed understanding of its precipitation patterns for effective water management. This study assesses spatiotemporal precipitation dynamics across Sindh from 2001 to 2024 by integrating satellite-based CHIRPS data, in situ observations from the Climate Knowledge Portal (CKP), and CMIP6 climate model projections. Validation results show strong agreement between CHIRPS and ground data (R ≈ 0.87, d ≈ 0.93), confirming the sate [...]

by Jozélio Freire de Carvalho  and Rosangela Passos de Jesus

Received: 03 November 2025;  Published: 23 February 2026;  doi: 10.21926/rpn.2601003

Dietary factors influence chronic inflammation and immune regulation, potentially affecting the onset and activity of rheumatic disease. Red meat, a major source of protein, heme iron, and saturated fat, has been linked to metabolic and inflammatory disorders, yet its role in rheumatic diseases remains unclear. To comprehensively evaluate the relationship between red-meat consumption and major rheumatic diseases—including rheumatoid arthritis (RA), gout, systemic lupus erythematosus (SLE), and other inflammatory or [...]

by Jozélio Freire de Carvalho  and Rosangela Passos de Jesus

Received: 27 October 2025;  Published: 13 February 2026;  doi: 10.21926/rpn.2601002

Selenium (Se) is a key micronutrient integrated into selenoproteins such as glutathione peroxidases (GPx), which are responsible for crucial antioxidant and anti-inflammatory mechanisms. Oxidative stress contributes to the immunopathogenesis and chronic joint damage of rheumatoid arthritis (RA), supporting interest in selenium supplementation as an adjunct therapeutic strategy. This review was based on a structured literature search of major biomedical databases and evaluated six controlled clinical trials involvin [...]

by Emeka H. Amalu  and Justice O. Nwaneto

Received: 26 June 2025;  Published: 13 February 2026;  doi: 10.21926/jept.2601003

As the demand for cleaner-greener energy surges owing to more nations adopting Net Zero Emission by 2050, wind turbine (WT) technology is increasingly poised as one of the technologies to match the demand. Capacity building in the development of cost-effective WT tower with improved reliability and safety has become critical to delivering Net Zero mandate. This research demonstrates implementation of Taguchi Design of Experiment (DoE) in conjunction with Signal-to-noise ratio (S/N) to optimise both structural desig [...]

by Katherine Lucre  , Fatema Bhalloo  , Louis Brown  and Angela Foster

Received: 13 October 2025;  Published: 13 February 2026;  doi: 10.21926/obm.icm.2601009

It has become increasingly evident that individuals who work in the NHS can be heavily impacted by the nature of their work; for instance, PTSD, work related burnout, vicarious trauma, moral injury, anxiety, and depression. In turn, individuals who experience said psychological difficulties often require work-related mental health leave from work. This paper examines the experience of a One-day Compassionate Mind Training workshop (CMT), available for all NHS staff. This day has an emphasis on developing multidirec [...]

by Mathivathani Kandiah  , Nasmah Nisthar  , Beneli Gunaratne  and Ominda Perera

Received: 30 October 2025;  Published: 12 February 2026;  doi: 10.21926/cr.2601004

The advancement of photocatalytic nanomaterials has become central to addressing the growing challenge of removing organic pollutants from water systems through sustainable and efficient degradation pathways. In this study, silver nanoparticles were synthesized via a green approach using aqueous extracts derived from five parts of Flacourtia indica, including bark, flower, fruit, seed, and leaves, at 90°C for 45 minutes. UV–VIS spectroscopy (460 nm) confirmed nanoparticle formation, while scanning electron microsco [...]

by Mohammed H. Moghadasian

Received: 27 January 2026;  Published: 12 February 2026;  doi: 10.21926/obm.transplant.2601266

Dietary guidelines and Nutrient Reference Intakes are important tools for maintaining optimal health in the general population. Similar guidelines have also been developed by specific organ health associations to help their patient populations recover from disorders or prevent/delay clinical events and subsequent complications. However, there are no specific national and international guidelines to provide dietary and nutrient intake recommendations peri-transplantation. The complex nature of transplantation and in [...]

by Mona-Elisa Eberharter

Received: 03 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.neurobiol.2601324

Using a two-stage qualitative design (Stage 1: expert interviews; Stage 2: biographical interviews with people with MS), existing governmental and organizational support measures for maintaining the work capacity of individuals with multiple sclerosis (MS) were analyzed, and proposals for improvement were developed. Additional state support measures were proposed, including relaxing the criteria for state assistance, creating a centralized contact point for MS-specific inquiries, and enhancing collaboration between [...]

by Bojana Anđelković  , Biljana P. Dojčinović  , Ivona Mihajlović  , Jelena M. Živković  and Nebojša Đ. Pantelić

Received: 10 November 2025;  Published: 12 February 2026;  doi: 10.21926/obm.icm.2601008

Persimmon (Diospyros kaki L.) is increasingly recognized as a nutrient-dense fruit rich in health-promoting compounds. This study aimed to comprehensively evaluate the nutritional composition, phenolic profile, antioxidant potential, and elemental content of D. kaki fruit and its contribution to dietary mineral intake. Proximate analysis revealed a high moisture content, low fat, and appreciable fiber and carbohydrate levels, supporting its classification as a low-calorie, fiber-rich food. Methanolic extracts exhib [...]

by Isabelle Wallach  , Julie Beauchamp  , Tamara Sussman  , Arianne Laplante  and Patrick Durivage

Received: 08 October 2025;  Published: 11 February 2026;  doi: 10.21926/obm.geriatr.2601335

The sexuality of older adults at advanced stages of illness, or at the end of life, remains a taboo topic that is rarely addressed in the literature and in practice. As a result, the knowledge base informing the support needs of older adults at the final stages of life with regards to sexuality remains scant. The present study seeks to explore experiences of sexuality in older adults with serious illness or receiving palliative care, focusing specifically on the place of sexuality in their lives, the forms of sexua [...]

by Agegnehu Kitanbo Yoshe

Received: 08 November 2025;  Published: 10 February 2026;  doi: 10.21926/aeer.2601003

Characterizing drought severity using GRACE and TerraClimate datasets is globally important because it enables consistent, large-scale monitoring of both surface and subsurface water availability across data-scarce regions. This integrated perspective supports improved drought assessment, climate change impact analysis, and informed water-resource management worldwide. The Ethiopian Rift Valley has experienced recurrent hydrological drought hazards, posing serious threats to water availability, agricultural product [...]

by Fabrizio Stasolla  , Enza Curcio  , Antonio Zullo  , Mariacarla Di Gioia  and Anna Passaro

Received: 04 November 2025;  Published: 10 February 2026;  doi: 10.21926/obm.neurobiol.2601323

Mathematical learning often presents persistent challenges for children and adolescents with Autism Spectrum Disorder (ASD) due to differences in Executive Functioning (EF), cognitive flexibility, and symbolic reasoning. These factors can hinder the development of numerical understanding and pre-mathematical reasoning, problem-solving, and abstract thinking, frequently resulting in disengagement and anxiety. In recent years, digital and embodied technologies—particularly Serious Games (SG) and Educational Robotics [...]

by Mojtaba Ehsanifar  , Akram Gholami  , Nioosha Pahnavar  , Reyhaneh Shenasi  and Maryam Golmohammadi

Received: 27 October 2025;  Published: 09 February 2026;  doi: 10.21926/obm.neurobiol.2601322

Mycotoxins, toxic secondary metabolites produced by fungi and molds, have negative health impacts on both humans and animals. They are commonly found in foods such as nuts, coffee, cereals, and grains, particularly in regions with warm, humid climates. Among the most prevalent mycotoxins in these foods are aflatoxin B1, ochratoxin A, zearalenone, patulin, and deoxynivalenol (DON). The presence of mold capable of producing mycotoxins within food contributes to an elevated risk of various illnesses, including those r [...]

by Reyhaneh Bakhtiari  , Michelle V. Tomczak  , Stephen D. Langor  , Aaron Granley  , Farah Campbell  and Anthony Singhal

Received: 02 September 2025;  Published: 05 February 2026;  doi: 10.21926/obm.geriatr.2601334

Driving is a complex cognitive behavior that is an essential part of everyday life and can be broken down into many subcomponents. Due to aging and medication interactions, a wide range of motor, sensory, and cognitive skills that are imperative for driving are affected in older adults. Several studies show that the number of crashes and mortality rates increase by age and the consumption of cannabis and cocaine is associated with a range of adverse mental and physical effects. The purpose of this study was to iden [...]

by Vivek Shekhar  and Hester O Connor

Received: 29 October 2025;  Published: 04 February 2026;  doi: 10.21926/obm.icm.2601007

The innate desire to belong and to connect is profoundly human, yet in a world of instant communication, millions of young people increasingly feel untethered and adrift. Loneliness is the 21st century's primary health care concern across all age groups. Young people not only feel lonely and emotionally isolated, but they also describe a lack of meaningful connections and purpose. Young people lack safe spaces where they can connect with their peers, without fear of judgment, prejudice, and pressure to succeed. In [...]

by Rafaele Tavares Silvestre  , Mariana Chantre-Justino  , Mariana Alexandre Bragante  , Paula Lacorte de Carvalho  , Lucas Delmonico  , Gilda Alves  , Maria Helena Ornellas  and Dirce Bonfim de Lima

Received: 31 May 2025;  Published: 04 February 2026;  doi: 10.21926/obm.genet.2601326

Advances in antiretroviral therapy (ART) have normalized the life expectancy of people living with HIV (PLWH) but have been linked to a premature presentation of age-related comorbidities, including cancer. Telomere length (TL) is a marker of cellular aging and was investigated in blood leukocytes from 78 PLWH on ART, compared with 163 HIV-uninfected controls. The PLWH group was stratified into three subgroups: HIV-only (n = 57), HIV with AIDS-defining cancer (ADC, n = 9), and HIV with NADC (n = 12). Quantitative p [...]

by Enesi Y. Salawu  , Opeyemi E. Akerekan  , Femi E. Adegbite  , Olasehinde O. Nifemi  , Samson O. Ongbali  , Joseph O. Dirisu  , Ogunkola B. Abiodun  and Emmanuel O. Ajanaku

Received: 27 October 2025;  Published: 02 February 2026;  doi: 10.21926/rpse.2601002

In bottling companies, spur gears play a vital role in ensuring efficient mechanical power transmission in bottling machines. Therefore, the maintainability of spur gears in these machines is important because it directly affects the overall efficiency, productivity, and cost-effectiveness of bottling operations. The study focused on data collection for different tasks performed on a failed gear from January to December of a particular year based on task time and frequency of occurrence, which are important factors [...]

by Walter Paganin

Received: 30 July 2025;  Published: 27 January 2026;  doi: 10.21926/obm.neurobiol.2601321

Difficult-to-treat depression (DTD) with inflammatory features (e.g., hs-CRP ≥3 mg/L and/or elevated IL-6) may represent a clinically and biologically distinct presentation characterized by chronicity, functional impairment, prominent cognitive-motivational symptoms, and suboptimal response to conventional treatments. Classical anti-inflammatory strategies (e.g., COX-2 inhibitors or cytokine-targeting biologics) have shown signals of efficacy in selected biomarker-enriched subgroups; however, overall evidence remai [...]

by Mohsen Khosravi

Received: 19 September 2025;  Published: 26 January 2026;  doi: 10.21926/obm.neurobiol.2601320

Personalized psychopharmacotherapy remains a critical yet underdeveloped frontier in psychiatry, as traditional approaches often fail to address substantial interindividual variability in drug efficacy and tolerability. While demographic, clinical, and genetic factors have improved treatment precision, they do not fully account for observed heterogeneity. Recent advances highlight the promise of personality traits, particularly as operationalized by Cloninger’s Seven-Factor Model, as novel biomarkers for treatment [...]

by Svetlana I. Kulakovskaya  , Tatyana S. Zyubina  , Alexander S. Zyubin  , Alexander V. Kulikov  and Yuriy A. Dobrovolskiy

Received: 07 August 2025;  Published: 26 January 2026;  doi: 10.21926/cr.2601003

Electrocatalytic oxidation of organic compound in the absence of noble metals or their oxides as catalysts and using metal-free electrodes is a "green" electrochemical, inexpensive and attractive process for practical use in electrocatalysis, power sources and sensors. The process accompanied by the elimination of protons, is of interest both for obtaining valuable organic compounds at the anode and for the release of hydrogen evolution at the cathode. In this work, the catalytic oxidation of cyclohexanol in the pr [...]

by Edward Caddye  , Yuliia Lukianstseva  , Richard Aceves  and Guy W. Fincham

Received: 28 July 2025;  Published: 22 January 2026;  doi: 10.21926/obm.icm.2601006

This paper introduces Movement-informed Breathwork (MiB), a personalised breath-body approach with biofeedback that integrates a form of conscious connected breathwork (breathing without pauses) with targeted neuromuscular contraction and relaxation cycles. Drawing from neuromuscular torque chain dynamics, fascial research and sensorimotor trauma therapy principles, MiB aims to enhance autonomic regulation, interoceptive awareness and somatic-emotional integration by bridging traditional breathwork (deep, slow-pace [...]

by Chawannuch Ruaengsri  , Miguel Alvarez-Cortes  , Marc Leon  , Manuel Quiroz-Flores  , Masafumi Shibata  and Yasuhiro Shudo

Received: 30 June 2025;  Published: 22 January 2026;  doi: 10.21926/obm.transplant.2601265

The increasing demand for organ transplantation has necessitated innovative strategies to maximize donor organ utilization, especially in donation after circulatory death (DCD) contexts. This article explores the integration of direct lung recovery with abdominal normothermic regional perfusion (A-NRP) to optimize organ preservation and expand the donor pool. A-NRP effectively mitigates warm ischemic injury, supporting the viability of both abdominal and thoracic organs. Our approach emphasizes meticulous surgical [...]