by Michael Fossel

Received: 29 January 2019;  Published: 30 January 2019;  doi: 10.21926/obm.geriatr.1901031

Telomere Editorial-Perspectives on Telomeres and Aging

by Éilish A. Burke  , Rachael Carroll  , Angela W. Ding  , Melisa Yaman  , J. Bernard Walsh  , Philip McCallion  and Mary McCarron

Received: 23 June 2021;  Published: 08 November 2021;  doi: 10.21926/obm.geriatr.2104182

Globally between 30-40% of all osteoporotic fractures occur among men, with a quarter of all hip fractures, the most serious complication of osteoporosis, occurring in men. Among men of 50 years of age or older, osteoporotic fracture risk reaches an alarming 20%. What is of great concern is that associated mortality is greater among men when compared with women. For hip fractures specifically, mortality for men is two to three times that in women which may be attributed to the fact that osteoporosis is often consid [...]

by Matthew Adah Onu  , Olusola Olaitan Ayeleru  , Helen Uchenna Modekwe  and Peter Apata Olubambi

Received: 28 August 2023;  Published: 29 December 2023;  doi: 10.21926/aeer.2304055

Plastic waste accrual in the environment has been identified as the topmost significant global issue related to modern civilization. Traditional waste disposal methods, such as open burning, landfilling, and incineration, have increased greenhouse gas emissions in economic and material losses. Unless immediate action is made to curtail demand, prolong product lifespans, enhance waste management, and encourage recyclability, plastic pollution will increase due to an almost threefold increase in plastic use spurred b [...]

by Carmelo Guido  , Valentina Selmi  , Cosimo Chelazzi  , Giulia Borsotti  , Rita Giachetti  , Vittorio Limatola  , Martina Sicurani  and Angelo Raffaele De Gaudio

Received: 29 September 2018;  Published: 28 March 2019;  doi: 10.21926/obm.icm.1901020

Background: In recent years, complementary and alternative medicine (CAM) techniques have become very widespread; among these, acupuncture can play an important role in the treatment of adverse effects related to chemotherapy. This role has been recognized by the National Institutes of Health after many clinical studies, thus allowing the official introduction of acupuncture in supportive therapy for oncological diseases, particularly to prevent nausea and vomiting. The aim of this paper is to describe the activity [...]

by Dayu Lv  , Jose Garcia-Tirado  and Chiara Fabris

Received: 17 May 2018;  Published: 11 September 2018;  doi: 10.21926/obm.transplant.1803019

Background: Human pancreatic islet transplantation is a minimally-invasive procedure that is gaining recognition for the treatment of type 1 diabetes (T1D). Selected patients with unstable T1D, hypoglycemia unawareness, history of severe hypoglycemia, and glycemic lability, not successfully stabilized with intensive insulin treatment, can be offered this alternative therapy that has been shown to provide long-term glycemic control with near-normalization of hemoglobin A1c in the absence of severe hypoglycemia. Toda [...]

by Walter Milano  , Paola Ambrosio  , Francesca Carizzone  and Anna Capasso

Received: 19 November 2019;  Published: 13 April 2020;  doi: 10.21926/obm.neurobiol.2002055

Anorexia nervosa is a psychiatric disorder, the etiopathogenesis of which is still not fully understood. Currently, the most accredited model is a multifactorial model, which involves interaction between predisposing factors of biological nature, partly genetically determined, and psychological/personological and environmental socio-cultural factors. The last 20 years have led to the advancement in our knowledge on the mechanisms of energy homeostasis maintenance. There has been a veritable explosion of studies aim [...]

by Francisco V. Muñoz  and Linda Larkey

Received: 20 May 2020;  Published: 27 July 2020;  doi: 10.21926/obm.icm.2003035

Breast cancer survivors (BCSs) report decrements in cognitive functioning. A Meditative Movement (MM) program (Qigong/Tai Chi Easy) combines meditation and exercise, practices known to improve cognitive function. Method: Using a single group, pre- to post-intervention assessment design, a pilot study was conducted in BCSs to test the effects of an 8-week MM intervention on cognitive functioning, sleep and mood and to explore changes on selected gene expression factors, BDNF, NF-kB1, and TP53, expected to improve wi [...]

by Tina Rawal  , Jean W.M. Muris  , Vijay Kumar Mishra  , Monika Arora  , Nikhil Tandon  and Onno C.P. van Schayck

Received: 10 January 2022;  Published: 30 March 2022;  doi: 10.21926/rpn.2201010

COVID-19 greatly affected the lives of adolescents through restrictions such as less playtime, more screen time, and limited interaction with peers. In this study, we assessed the impact of the COVID-19 pandemic on the dietary and physical activity-related behavior of school students aged 10–16 years. This cross-sectional study was conducted with adolescents recruited from seven randomly selected private schools in Delhi, India, during 2021. A self-administered web-based survey was conducted to evaluate the behavio [...]

by Kjeld C. Engvild

Received: 17 July 2019;  Published: 03 December 2019;  doi: 10.21926/obm.genet.1904100

Hansemann-Boveri’s aneuploidy theory, the Warburg effect, and the Knudson hypothesis can be viewed as different aspects of a single theory of cancer. In this, the extremely common chromosome missegregation may be the underlying cause. Chromosome missegregation is mitigated via several mechanisms. Cancer can occur only when all of these mechanisms have been inactivated in a single cell line, typically by mutation. There are at least five different repair mechanisms, implying a hit-factor of at least five. These miti [...]

by Johannah Ruddy  and Kate Scarlata

Received: 05 August 2022;  Published: 13 February 2023;  doi: 10.21926/rpn.2301003

Celiac disease (CD) is a multisystem immune-mediated disorder resulting in enteropathy of the small intestine with the ingestion of gluten, in genetically susceptible individuals. This condition impact 1% of the population and can result in the development of other conditions such as chronic fatigue, anemia, osteoporosis, aphthous stomatitis, elevated liver enzymes, joint pain, infertility, peripheral neuropathy, and epilepsy. In this review, we outline the clinical presentation of CD, the physiological differences [...]