by Meshari A. Alzahrani  , Mohammad A. Alghafees  , Lama H. Aldosari  , Abdulaziz K. Almaymuni  , Abdulltaif M. Altalhah  , Mohammed M. Abualgasem  and Basel O. Hakami

Received: 19 April 2024;  Published: 30 September 2024;  doi: 10.21926/obm.genet.2403265

The total lack of spermatozoa in the ejaculate is known as Azoospermia. It is the most severe and significant contributor to male infertility. Therefore, the purpose of this study is to assess the status of Azoospermia and its etiologic factors that contribute to male infertility in Saudi Arabia. This study included all published studies written in English that were published in Saudi Arabia. Online searches via PubMed and Google Scholar were conducted from their inception to 15 January 2023. A total of 624 studies [...]

by Mario F. Tecce  , Walter Milano  and Anna Capasso

Received: 26 June 2020;  Published: 31 August 2020;  doi: 10.21926/obm.icm.2003038

Adipocytes play a central role in maintaining lipid homeostasis and energy balance by storing triacylglycerols (TAGs) or releasing free fatty acids in response to changes in energy requirements. Obesity is a major risk factor for many diseases, including diabetes, hypertension, and cardiovascular disease. Besides, morbidity and mortality associated with being overweight and obese are on the rise. The development of obesity is characterized by an increase in lipid cells due to mitogenesis and differentiation, which [...]

by Bradley Jorgensen

Received: 24 October 2022;  Published: 18 January 2023;  doi: 10.21926/aeer.2301009

The Contingent Valuation (CV) Method, like other stated preference techniques, seeks to measure economic preferences for public goods. Throughout the development and application of this non-market procedure, the accuracy of the measured preferences has been front-and-centre among practitioners and potential users. The most important issue of debate has been the extent to which the method can reliably measure economic preferences. In this article, a new methodology is described that enables multiple indicators of la [...]

by Vincenza Rita Lo Vasco

Received: 01 October 2019;  Published: 18 May 2020;  doi: 10.21926/obm.neurobiol.2002058

Mechanisms leading to neuronal cell death in human pathology are far from being fully delineated. Understanding the molecules involved in neuronal death and the timing of their recruitment might help to explain the natural history of degenerative processes, including the morphological abnormalities observed in Alzheimer’s disease (AD). Moreover, it might help refine the diagnosis by defining new molecular markers as well as find effective therapies, especially for slow cognitive deficits, often associated wit [...]

by Joun Park  , Xianzun Tao  and R. Grace Zhai

Received: 13 January 2020;  Published: 20 March 2020;  doi: 10.21926/obm.genet.2001106

By adjusting gene expression in response to environmental changes, cells can optimize fitness as needed. Alternative splicing is one of the most important post-transcriptional regulation steps, broadly involved in diverse physiological and pathological conditions. Here, we present 5 cases of alternative splicing conferring increased neuroprotection through diverse mechanisms. These examples highlight the enormous power of alternative splicing in maintaining viability of neurons. From pre-mRNA secondary structure al [...]

by Maria E. Pushpanathan  , Andrea M. Loftus  , Natalie Gasson  , Meghan G. Thomas  and Romola S. Bucks

Received: 13 May 2019;  Published: 23 September 2019;  doi: 10.21926/obm.geriatr.1903075

Background: Both disrupted sleep and cognitive impairment are frequent in Parkinson’s disease (PD), but the evidence for a relationship between self-reported sleep disturbance and cognitive symptoms has been equivocal. If sleep symptoms differentially predict cognition in different subtypes, effects may be obscured in a general PD sample. Objective: First, to determine whether the associations between participant and disease variables, sleep symptoms and cognitive performance vary by subtype (younger and olde [...]

by Kesiena Owebor  , Smith Orode Otuagoma  , Ogheneakpobo Jonathan Eyenubo  , Arthur Gogo Uranta  , Friday Erhimudia Ukrakpor  , Kesiena Ezewu  and Ebimene Ezekiel Ebisine

Received: 01 August 2023;  Published: 08 November 2023;  doi: 10.21926/jept.2304033

The proper management of sawdust is critical to socioeconomic development. In this research, waste-to-energy has been proposed to utilize sawdust in selected timber markets in Port Harcourt, namely, Illoabuchi Timber Market, Marine Base Timber Market, and Mile 3 Timber Market. A quantitative approach has been taken to estimate the sawdust generation, energy potential, power generation capacities, and pollutant reduction of indiscriminate combustion of sawdust. The findings suggest that, annually, 171 ktons, 42 kton [...]

by Ferah Armutcu

Received: 01 June 2024;  Published: 24 September 2024;  doi: 10.21926/obm.icm.2403055

Intermittent fasting practices, recommended as a potential nutritional approach against obesity and metabolic diseases, have become increasingly widespread in recent years. Although convincing data on the anti-obesity and cardio-metabolic benefits of intermittent fasting are obtained mostly from experimental studies, religious and traditional fasting practices have been among the treatment methods applied for human health for centuries. Both intermittent fasting and religious fasting may be a promising strategy for [...]

by Phillip Aouad  , Nerissa Soh  and Kristin Stedal

Received: 05 May 2020;  Published: 18 August 2020;  doi: 10.21926/obm.neurobiol.2003070

Consensus for where along the eating disorder spectrum the pathological eating behaviour of Chew and Spit (CHSP) falls has been a point of contention in academic literature. Using the case of Mary1, a 30 year old female from Australia who has engaged in excessive restrictive behaviour, was diagnosed with anorexia nervosa (AN) and has been engaging in Chew and Spit (CHSP) behaviour for over 10 years, the current paper examines the similarities from a neurobiological perspective between restrictive behaviours (akin w [...]

by Ahalapitiya H Jayatissa  , Omer Ahmed  , Bodhi R Manu  and Adam M Schroeder

Received: 13 August 2020;  Published: 22 January 2021;  doi: 10.21926/rpm.2101003

The tribological properties of ZnO thin film coated on an aluminium work piece by RF magnetron sputtering were studied as a function of deposition power, substrate coating temperature, heat treatment and rotation speed. The variation in the coefficient of friction of ZnO films produced under various levels of coating parameters and conditions were experimentally determined using a pin-on-disk tribometer. The results showed that with change in deposition conditions and heat treatment, there are significant microstru [...]