by Mieczysław Szyszkowicz

Received: 14 April 2021;  Published: 10 June 2021;  doi: 10.21926/aeer.2102014

Each country has its own characteristics of COVID-19 infection trajectory and epidemic waves. Differences in government-implemented restrictions and social regulations result in variability of the virus transmissions and spread dynamics. This in turn results in various shapes of the growth function used to represent and describe the propagation of infection. Statistical methods are applied to fit non-linear functions to represent daily time-series data of the cumulative numbers of COVID-19 cases. The aim of this wo [...]

by Chris R. Lavers  , Travis Mason  , Jonathan Mazower  and Sarah Grig

Received: 29 October 2020;  Published: 09 July 2021;  doi: 10.21926/aeer.2103018

High-resolution satellite imagery permits acquisition of critical data to observe climate-change and environmental impact on conflict-impacted indigenous communities with co-existing socio-economic factors, often within unstable regimes. Conflict may prevent direct access in remote regions to validate civilian conflict actor evidence. In such cases use of remote sensing tools, techniques, and data are extremely important. Software-based imagery assessment can quantify radiometrically calibrated or Normalized Differ [...]

by Sri Desfita  , Denai Wahyuni  , Yusmarini Yusmarini  , Usman Pato  and Grazyna Budryn

Received: 09 April 2024;  Published: 23 August 2024;  doi: 10.21926/rpn.2403012

This systematic review aimed to analyze the in vivo study of the anti-osteoporotic activity of chickpeas. A comprehensive search for English language papers published between January 2013 and December 2023 using the keywords chickpea or Cicer arietinum, anti-osteoporotic activity or anti-osteoporotic effect, chickpeas and anti-osteoporotic activity, Cicer arietinum and antiosteoporotic activity and their synonyms yielded 3566 results from PubMed, ScienceDirect, SpringerLink and Google Scholar. Articles were screene [...]

by Nagarajan Paramasivam  , Martin Granzow  , Christina Evers  , Katrin Hinderhofer  , Stefan Wiemann  , Claus R. Bartram  , Roland Eils  and Matthias Schlesner

Received: 24 October 2017;  Published: 16 April 2018;  doi: 10.21926/obm.genet.1802017

Background: With genome sequencing entering clinics as a diagnostic tool to detect genetic disorders, there is an increasing need for bioinformatics-based solutions that enable precise causal variant identification in a timely manner. Workflows for the identification of candidate disease-causing variants usually perform the following tasks: i) identification of variants; ii) filtering of variants to remove polymorphisms and technical artifacts; and iii) prioritization of remaining variants to provide a small set of [...]

by Dean M. Cordingley  and Stephen M. Cornish

Received: 30 May 2022;  Published: 07 October 2022;  doi: 10.21926/obm.geriatr.2204206

Myokines are cytokines secreted from muscle during contraction and are implicated in autocrine, paracrine, and endocrine regulation of biological systems. It is postulated that myokines contribute to skeletal muscle adaptations in response to resistance exercise. Exercise, including resistance exercise, is an important factor in the management of maintaining skeletal muscle strength, mass, and function with aging. Sarcopenia is exacerbated with increased age and therefore, it is important to understand the potentia [...]

by Yoko Kawamura

Received: 15 May 2025;  Published: 30 October 2025;  doi: 10.21926/obm.geriatr.2504329

In Japan, a super-aging society, the development of Ikigai is considered the key to extending healthy longevity in national policy. Thus, activities provided by local governments are designed to encourage Ikigai. At this point, Ikigai has developed its conceptual understanding, which includes its distinctiveness from life purposes and other closely related concepts. Empirical studies using developed measurements have shown that Ikigai has an impact on the mental and physical health of older adults across countries [...]

by Heath Murray  and Mehdi Khaki

Received: 23 October 2020;  Published: 29 July 2021;  doi: 10.21926/aeer.2103019

Inland water bodies are crucial for supporting human life in various parts of the world. Therefore, it is essential to accurately monitor its spatiotemporal variations for better water management. The main objective of this study is to investigate the application of remote sensing data for quantifying the surface area changes and the impact of climatological variabilities over Lakes Mead and Chapala. Historical time series of monthly surface area dynamics were developed using Landsat 1-8 scenes and the climate vari [...]

by Allison Ast  , Margaret Meyer  , R. Elyse Heidelberg  , Jennifer M. Allen  , Amy Ly  and Holly Spraker-Perlman

Received: 02 December 2020;  Published: 08 February 2021;  doi: 10.21926/obm.icm.2101005

Children with cancer can experience intense suffering. Currently, despite our best efforts, symptoms associated with both cancer and its treatment result in physical, psychological, and emotional discomfort that can be difficult to manage with traditional Western medicine alone. Developing integrative services within a pediatric hematology-oncology program may help improve cancer-related symptoms by combining different modalities targeting overall health with traditional oncology care. This study details the initia [...]

by Shingo Nakamura  , Naoko Ando  , Masayuki Ishihara  and Masahiro Sato

Received: 09 August 2020;  Published: 16 November 2020;  doi: 10.21926/obm.genet.2004119

The liver is a major organ with a wide range of functions, including detoxification, protein synthesis, and bile production. Liver dysfunction causes liver diseases such as hepatic cirrhosis and hepatitis. To explore the pathogenesis of these liver diseases, and the therapeutic agents against them, mice have been widely used as animal models. Genetic manipulation is easy in mice via the administration of nucleic acids (NAs) in the tail-vein. In particular, hydrodynamics-based gene delivery (HGD) is a method based o [...]

by Navya Uppu  , Kelly McMahen  , Tasneem Khasru  and Mark A. DeCoster

Received: 02 August 2022;  Published: 17 October 2022;  doi: 10.21926/rpm.2204020

Green synthesis of nanomaterials endeavors to reduce the use of high energy methods with those that may include lower temperatures and pressures, use of natural products, and bottom-up self-assembly. Here we describe the generation of metal-organic biohybrids (MOBs) with nanoscale features synthesized at physiological (37°C) and room temperature (25°C). These MOBs utilized the naturally occurring amino acid dimer cystine as the biological component, and a series of metals, including copper, silver, and cobalt. The [...]