by Naiwei Chi  , Shuyao Zheng  , Elwin Clutter  and Rong Wang

Received: 30 October 2019;  Published: 18 December 2019;  doi: 10.21926/rpm.1904007

Background:Diabetic patients suffer from chronic wounds partly due to altered function of fibroblasts. Fibroblasts of diabetic patients synthesize collagen I (COLI) at a much higher level than collagen III (COLIII), resulting in delayed tissue granulation and, consequently, a delay in the overall wound healing process. Methods:We aimed to revive the matrix protein productivity of diabetic fibroblasts by employing aligned, electrically conductive and biocompatible spider silk-CNT fibers as a cell culture matrix to m [...]

by Carol Tran  and Laurence J. Walsh

Received: 28 September 2021;  Published: 26 November 2021;  doi: 10.21926/rpm.2104046

Subsurface remineralization can be promoted by the topical application of nanoparticles of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). To assess changes in enamel white spot lesions, an in situ proof-of-concept investigation was performed using 5 subjects (all of whom were healthy young adults) with a cross-over study design. Custom orthodontic brackets were attached to the buccal surfaces of the maxillary second premolar and first molar teeth. Each bracket had a recess that held a slab of enamel w [...]

by Alpha Chukwumela Ajie  , Mohammed Moore Ojapah  and Endurance Ogheneruona Diemuodeke

Received: 07 February 2023;  Published: 20 June 2023;  doi: 10.21926/jept.2302020

With their higher sustainability index, biofuels, environmentally-friendly and renewable nature is a viable alternative energy source in the transportation sector. This study presents the effect of waste cooking oil (WCO) biodiesel on performance, combustion, and emission from a compression ignition engine. The biodiesel was blended with diesel in varying proportions of 5% biodiesel and 95% diesel (designated as B5), 10% biodiesel in diesel (B10), 15% biodiesel in diesel (B15), 20% biodiesel in diesel (B20), 50% bi [...]

by Angela Q Maldonado  , Kristoffer Sjöholm,  , Joshua Lee  , Håkan Olsson  , Christian Kjellman  and Darren E Stewart

Received: 01 April 2021;  Published: 03 June 2021;  doi: 10.21926/obm.transplant.2102143

Prioritization in the US Kidney Allocation System (KAS) has led to an improvement in the rates of transplantation in highly sensitized (HS) patients. However, there is a subset of HS patients who are at a disadvantage, despite prioritization under KAS. The purpose of this study was to describe the transplant rate (TR) by calculated panel reactive antibody (CPRA) of HS candidates before and five years post-KAS to characterize their access to deceased donor transplants and quantify the number of HS candidates who are [...]

by Tamuyen P. Do  , Eileen B. O'Keefe  and Nicole L. Spartano

Received: 04 June 2020;  Published: 23 September 2020;  doi: 10.21926/obm.geriatr.2003133

Individuals with dementia frequently report poor quality of life (QOL), which declines as their disease progresses. Some evidence suggests that physical activity may help maintain cognitive function in older age, but it is unclear whether physical activity affects quality of life in older adults with dementia. The purpose of this review paper is to explore whether and how physical activity impacts QOL in patients with diagnosed dementia in different residential settings. To conduct this systematic review, the follo [...]

by Debora Di Jorio

Received: 14 April 2020;  Published: 22 June 2020;  doi: 10.21926/obm.neurobiol.2002063

The story of each individual is essentially the story of their learning processes and relationships from the moment they were born. Indeed, the story of learning processes is merely a constant stratification of experiences based on biological and neurofunctional features that are influenced by genetic and cultural factors and subject to environmental stimuli constantly reshaping their behaviour.Neuroscientific studies conducted over the past decades have highlighted a unique feature of the human nervous system, cal [...]

by Rachel Snodgrass  , Joanna Carnell  and Tim Chapman

Received: 31 May 2022;  Published: 10 August 2022;  doi: 10.21926/obm.icm.2203035

This study presents a mixed methods evaluation of a transdiagnostic Compassion Focused Therapy (CFT) group intervention, for adults with long-term health conditions (LTHCs). It aims to assess whether group completion was associated with improved outcomes in mood, overall well-being and the extent of LTHC interference in confidence for managing daily activities. Additionally, it examines the extent to which changes were related to processes targeted by CFT. The ‘Living Well with Illness’ group consisted of eleven we [...]

by Myia S. Williams  , Keyla Ordonez  , D’Arcy King  , Jeffrey Solomon  , Suzanne Ardito  , Jennifer Polo  , Sindee Weiss  and Negin Hajizadeh

Received: 21 April 2024;  Published: 18 October 2024;  doi: 10.21926/obm.icm.2404060

We explored the feasibility of a virtual-reality delivered mindfulness training intervention on burnout symptoms among corporate employees and clinicians in the Intensive Care Unit and Palliative Care Unit (PCU). To develop the VR mindfulness intervention we leveraged the Capability, Opportunity, Motivation, Behavior model (COM-B) as a guide for the design and implementation of the VR mindfulness training intervention. Using a pre-posttest within subjects design we assessed burnout syndrome, job stress and work-rel [...]

by Aaron R. Dezube  , Ashley L. Deeb  and Michael T. Jaklitsch

Received: 25 June 2021;  Published: 15 October 2021;  doi: 10.21926/obm.neurobiol.2104109

Myasthenia Gravis (MG) is a rare autoimmune disorder characterized by antibody mediated blockade of neuromuscular transmission. Up until the last decade, evidence suggesting benefit of thymectomy for myasthenia gravis has been based on non-randomized control studies. Our paper serves as an expert narrative review of new literature pertaining to surgical management of myasthenia gravis based on review of articles from PubMed and Cochrane database from date of inception through June 14, 2021. We used the MeSH search [...]

by Cristóbal Coronel-Rodríguez  and Alejandro Rodríguez-Martínez

Received: 10 May 2020;  Published: 24 July 2020;  doi: 10.21926/obm.neurobiol.2003067

This paper presents the case of a child diagnosed with both celiac disease and Asperger’s syndrome. The literature does not report this association to date, and the authors believe it to be a coincidence rather than a casualty.