Table of Content

Open Access Review

Religious and Traditional Fasting May Be an Alternative Method to Tackle Global Health Threats and the Epidemic of Obesity

Received: 01 June 2024;  Published: 24 September 2024;  doi: 10.21926/obm.icm.2403055

Abstract

Intermittent fasting practices, recommended as a potential nutritional approach against obesity and metabolic diseases, have become increasingly widespread in recent years. Although convincing data on the anti-obesity and cardio-metabolic benefits of intermittent fasting are obtained mostly from experimental studies, religious and traditional fasting practices have been among the treatment methods applied for human health for centuries. Both intermittent fasting and religious fasting may be a promising strategy for [...]

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Open Access Original Research

Experience with Alpha-1 Proteinase Replacement Post-Lung Transplantation in Alpha-1 Antitrypsin Deficiency: A Single Center Case Series

Received: 14 July 2021;  Published: 15 October 2021;  doi: 10.21926/obm.transplant.2104153

Abstract

Alpha-1 antitrypsin deficiency (AATD) accounts for approximately 5% of lung transplants (LTx) performed annually. No studies have addressed the potential benefit of ongoing alpha-1 proteinase inhibitor (A1-PI) replacement to AATD patients post-LTx. Our primary objective was to assess potential benefits of continually administering A1-PI from pre- to post-transplantation for AATD LTx recipients. A retrospective case series was performed on AATD LTx recipients between 2002 and 2018. Data reviewed included date of A1- [...]

1615 14369

Open Access Review

Reminiscence from Half a Century of Anti-Pneumocystis Drug Discovery and Development

Received: 12 September 2018;  Published: 06 December 2018;  doi: 10.21926/obm.genet.1804052

Abstract

My experiences with the identification and development of the anti-Pneumocystis drugs trimethoprim-sulfamethoxazole, dapsone and atovaquone are recounted. Attention is drawn to certain often-overlooked aspects of these drugs, including their concomitant effects against infections other than Pneumocystis, matters of dosing and adverse effects. During the past four decades several million people worldwide received chemoprophylaxis and treatment with these drugs for Pneumocystis jirovecii pneumonia. The population of [...]

1938 14364

Open Access Case Report

Examination of Sustainable Water Management at Norway’s Major Hub Airport: The Case of Oslo Airport Gardermoen

Received: 22 October 2021;  Published: 15 December 2021;  doi: 10.21926/aeer.2104034

Abstract

The present study used a detailed qualitative longitudinal research approach to examine the trends of water consumption, wastewater volumes, and drainage water volumes in Oslo Airport Gardermoen, which is Norway’s major hub airport, between the years 2005 and 2020. An overall upward trend was observed in the water consumption at Oslo Airport Gardermoen, which was consistent with the growth in air traffic and aircraft movements during the study period. The annual water consumption per enplaned passenger was observed [...]

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Open Access Review

Recent Advances in the Production of Genome-Edited Animals Using i-GONAD, a Novel in vivo Genome Editing System, and Its Possible Use for the Study of Female Reproductive Systems

Received: 17 September 2023;  Published: 12 December 2023;  doi: 10.21926/obm.genet.2304207

Abstract

Gene-engineered animals created using gene-targeting technology have long been recognized as beneficial, valid, and valuable tools for exploring the function of a gene of interest, at least in early 2013. This approach, however, suffers from laborious and time-consuming tasks, such as the production of successfully targeted embryonic stem (ES) cells, their characterization, production of chimeric blastocysts carrying these gene-modified ES cells, and transplantation of those manipulated blastocysts to the recipient [...]

4128 14355

Open Access Review

Disturbed Ovarian Differentiation in XX;SRY-Negative Dogs

Received: 30 December 2018;  Published: 29 April 2019;  doi: 10.21926/obm.genet.1902074

Abstract

In a mammal, at the beginning of its development, the gonad is bipotential. The shift into a male or female pathway is coordinated by the sex chromosomal complement, which triggers a series of genetic pathways signaling the developmental pattern of the gonadal anlage. Being mutually exclusive, the differentiated gonad should be either a testis or an ovary. In females, the absence of SRY, a testis-determining gene, drives the signaling cascades controlling the ovarian differentiation. Albeit rare, disorders of the g [...]

2151 14347

Open Access Case Report

Stuart Stress Adaptation and Nola Pender's Model on Mental Nursing Care of Patients Schizophrenia: Case Study

Received: 20 July 2024;  Published: 12 October 2024;  doi: 10.21926/obm.neurobiol.2404249

Abstract

To describe the application of the Stuart Stress Adaptation and Nola Pender Models in mental nursing care for a patient with schizophrenia and risk of violent behavior. This research method used case studies. The sample is one patient with schizophrenia. Data collection is done through direct observation, interviews, and patient medical records. The results showed that the client showed a major nursing problem in the form of risk of violent behavior. Predisposing factors included passive childhood experiences and s [...]

1591 14347

Open Access Review

Enzymes in Poly(Butylene-Succinate) Industry: An Overview on Synthesis Routes and Post-Processing Strategies

Received: 16 June 2023;  Published: 08 November 2023;  doi: 10.21926/cr.2304026

Abstract

This paper will present some sectors in which enzymes can replace traditional catalysts in poly(butylene-succinate) industry, emphasizing the green chemistry aspects associated with these newer strategies.

1907 14325

Open Access Review

Avoiding a Grim Future: The Climate Crisis and Its Effects on Human Aggression and Violence

Received: 30 August 2022;  Published: 24 May 2023;  doi: 10.21926/aeer.2302034

Abstract

As the climate crisis has progressed, scientists have begun to ask, "How does a rapidly warming ecosystem impact human behavior?" As aggression scholars and non-professional environmentalists, it has become increasingly clear that the impact of the climate crisis, without intervention, will dramatically increase humans' exposure to risk factors known to cause aggressive and violent behavior. This article describes a model that explains the indirect and direct effects of the climate crisis on aggression and violence [...]

2243 14312

Open Access Research Article

Non-linear Dynamics and Chaotic Trajectories in Brain-Mind Visual Experiences during Dreams, Meditation, and Non-Ordinary Brain Activity States

Received: 30 April 2020;  Published: 11 June 2020;  doi: 10.21926/obm.neurobiol.2002061

Abstract

The present report discusses brain visual experiences in conditions of low degree of openness of the brain toward the environment, for example, while dreaming, during meditation, or in non-ordinary brain activity states such as under the effects of psychoactive substances, in the state of coma, or in other states of reduced sensory perception, among others. In the present report, for brevity, such states are referred to as brain-mind visual experiences, implying that such a visual activity is not one connected to t [...]

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