by Koji Naruishi

Received: 06 September 2018;  Published: 26 October 2018;  doi: 10.21926/obm.geriatr.1804016

In Japan, the amount of aged hospitalized patients has been steadily increasing. Elderly people are susceptible to poor health, and the rise of elderly patients increases medical care expenses, which can cause economic strain. Therefore, it is clinically and socially important to reduce the occurrence of geriatric diseases, such as aspiration pneumonia and cognitive impairment. The daily care by family members is considered to be effective for the prevention of geriatric diseases, however, early detection of the di [...]

by Maria Neve Ombra  , Filomena Nazzaro  and Florinda Fratianni

Received: 30 March 2023;  Published: 07 June 2023;  doi: 10.21926/rpn.2302008

Edible wild plants are a largely available food at no cost and an emblem of sustainability. Among the numerous varieties of edible wild plants, purslane (Portulaca oleracea L.) and common mallow (Malva sylvestris L.) are good sources of healthful bioactive compounds. Therefore, there is a growing interest in their consumption for health-related nutritional and sustainable perspectives. Fresh durum wheat tagliatelle fortified with dried and pulverized leaves of mallow or purslane at two distinct percentages of integ [...]

by Andrea P. Cuevas-Gómez  , Izlia J. Arroyo-Maya  and Humberto Hernández-Sánchez

Received: 26 April 2021;  Published: 22 June 2021;  doi: 10.21926/rpm.2102027

Whey protein is a byproduct of cheese, casein, and Greek yogurt produced in Europe, North America, and Australasia. It is a substantial source of functional proteins and peptides for the worldwide food industry. α-Lactalbumin (α-La) is a globular protein that can be isolated from WPI (whey protein isolates) using techniques such as chromatography/gel filtration, membrane separation, etc. α-La is used in the elaboration of functional foods and is a very good source of peptides with anticancer, antimicrobial, antivir [...]

by Sumita Jain  , Noufa Khan  , Yena Park  , Densen Cao  and Daniel CN Chan

Received: 02 May 2022;  Published: 15 June 2023;  doi: 10.21926/rpm.2302024

Zinc pyrithione (ZPT) is used to prevent microbial degradation and deterioration of manufacturing starting materials such as plastics, polymers, and latexes. The main objective of this study was to evaluate the anti-bacterial properties of ZPT. Currently, there is insufficient data on the effect of ZPT on viability of commonly encountered bacterial pathogens. We tested the efficacy of ZPT manufactured in the form of film rolls as an anti-bacterial protective layer by using the ASTM–recommended protocol on gro [...]

by Edwin Meresh  , David Daniels  , Jack H. Owens  , David Thompson  , Sarah Mennella  , Michael Levy  and Brenda Swartz

Received: 10 November 2019;  Published: 10 January 2020;  doi: 10.21926/obm.neurobiol.2001048

Agitation is a common manifestation of acute brain injury. When not addressed, agitation can lead to slower recovery rates, including delayed admission to acute rehabilitation programs. Antipsychotics are commonly used to control agitation in acute brain injury in the ICU. However, there is no current consensus on the most "efficacious and safest strategy" for use of antipsychotics in acute TBI. Haloperidol is arguably the commonly used antipsychotic for agitation in ICU setting at present. Interestingly, there are [...]

by Vincenzo Prisco  , Bernadette Donnarumma  and Lorenzo Prisco

Received: 02 December 2022;  Published: 22 March 2023;  doi: 10.21926/obm.geriatr.2301228

This paper discusses the history and the concept of somatization from masked depression to somatic symptoms and related disorders in the Diagnostic and Statistical Manual of Mental Disorders (DSM). Evaluating the evolution of these terms and concepts along the time course is very interesting. DSM 5 revision was intended to increase the relevance of these concepts in the primary care setting. “Masked depression” is a form of depression in which somatic symptoms or behavioral disturbances dominate the clinical pictur [...]

by Kathy Carter  , John Campbell  , Peyton Shoemaker  , Elisabeth Dichiara  , Neel Patel  and John Caruso

Received: 09 December 2021;  Published: 23 February 2022;  doi: 10.21926/rpn.2201005

Space flight imposes a myriad of adverse effects upon the human body. Improved in-flight nutritional strategies help mitigate those adverse effects. This review examines how space flight changes human physiology, and how improved in-flight nutritional strategies may address the unique dietary needs created by microgravity exposure. Dietary approaches and recommendations to address those needs are discussed. This review also describes food sustainability methods for long-term manned space flight, how precision nutri [...]

by Alejandro Ochoa-Ramirez  , Evelyn M. Kuhn  , Jitsupa Sirinit  and Theresa A. Mikhailov

Received: 11 October 2021;  Published: 26 January 2022;  doi: 10.21926/obm.icm.2201003

Many clinical, biochemical, and anthropometric factors have been used to determine the nutritional status of critically ill children. One of the most commonly used anthropometric measurements in children is the head circumference. It is used to assess their development, and in some instances, can be an indicator of chronic malnutrition. We aim to study the association between head circumference and the nutritional status of critically ill children under 2 years old. We retrospectively obtained the head circumferenc [...]

by Komeil Mirzaei Baboli  and Sumeet K. Mittal

Received: 29 October 2020;  Published: 05 February 2021;  doi: 10.21926/obm.geriatr.2101157

A 64-year-old, cachectic man with body mass index (BMI)

by Yi Song  , Carlos Rivera  , Jiayu Mai  , Annie Sun  and Weihan Li

Received: 23 March 2020;  Published: 22 May 2020;  doi: 10.21926/obm.genet.2002110

The majority of the secretory and transmembrane proteins are folded in the endoplasmic reticulum (ER). When unfolded proteins accumulate in the ER, a collective of signalling pathways, termed the unfolded protein response (UPR), are activated to restore the ER protein folding homeostasis. The most evolutionarily conserved branch of UPR is mediated by the kinase/endoribonuclease Ire1. Ire1 mediates a cytosolic non-conventional mRNA splicing reaction of HAC1 mRNA in yeast and XBP1 mRNA in mammalian cells. The spliced [...]