by David W. Scharp  , Jayagowri Arulmoli  , Kelly Morgan  , Hannah Sunshine  and Ergeng Hao

Received: 15 October 2018;  Published: 26 February 2019;  doi: 10.21926/obm.transplant.1901052

Background: This presentation of a six-year study processing human islets for research and transplantation includes a review of multi-center transplant studies identifying key variables critical for successful islet processing and defines standardized processing procedures required to provide highly purified, functional Human Islets. Methods: Human islet processing methods are defined in detail with pancreas retrieval, shipping, trimming for processing, collagenase distension, controlled digestion by digestion/filt [...]

by Foad Haeri  , Deepak Tapriyal  , Christopher Matranga  , Dustin Crandall  and Angela Goodman

Received: 05 September 2021;  Published: 05 November 2021;  doi: 10.21926/jept.2104046

Contact angles were measured for CO2-brine interactions on 20 different rocks that represent the properties of various CO2 storage depositional environments to characterize the wettability during geologic carbon storage. Three different CO2 phases (gaseous, liquid, and supercritical) were considered to investigate the effect of pressure and temperature. Bubbles were studied in two groups of larger and smaller than 500 μm, the latter being more relevant to pore scale. Variation was observed among contact angle measu [...]

by Alexander Manevich  , Simon Shimshon Rubin  , Rachel Ben-Hayun  , Judith Aharon-Peretz  and Michael Katz

Received: 07 September 2020;  Published: 12 March 2021;  doi: 10.21926/obm.geriatr.2101160

Caregiving for a loved one suffering from cognitive decline involves coping with many challenges and losses. This experience increases the risk of worsening the physical and mental health of the caregiver and has been the subject of a substantial number of studies focusing on the stress and burden of the primary caretaker. Theory and research on the grief reactions experienced by the family members, however, continues to lag in terms of the attention given to the behavioral and psychological burden of caregivers. T [...]

by Ana Monteagudo-Sánchez  , Marta Sánchez-Delgado  , Sonia Guara Ciurana  , Jose Medrano  , Maria Eugenia Poo-Llanillo  , Miho Ishida  , Gudrun E. Moore  , Isabel Iglesias-Platas  , Carlos Simón  and David Monk

Received: 29 May 2018;  Published: 29 July 2018;  doi: 10.21926/obm.genet.1803026

Background: Symmetrical DNA methylation profiles of autosomal genes are associated with equal expression by both alleles. Genes with an allelic imbalance or monoallelic expression are associated with discrete intervals of allele-specific methylation (ASM), as highlighted by genomic imprinting, X-chromosome inactivation and genotype-driven ASM. However, a more complex pattern has been described in which random monoallelic methylation provides cells with a unique mechanism for modulating allelic dosage. Methods: We c [...]

by Bo-Cai Gao  and Rong-Rong Li

Received: 26 April 2021;  Published: 05 July 2021;  doi: 10.21926/aeer.2103017

Passive high spatial resolution hyperspectral and multispectral imaging systems in the solar spectral region from aircraft and satellite platforms are being increasingly used for remote sensing of coastal waters and inland lakes. However, the remotely sensed data are often contaminated by the specular reflection of solar radiation at the air/water interface. Thus, the effects of sunglint need to be corrected. The purpose of sunglint correction is to remove the undesired specular reflected portion of radiance that d [...]

by Dieter Rehder

Received: 18 December 2019;  Published: 08 January 2020;  doi: 10.21926/acr.2001002

Vanadium is an element that is widely distributed in Earth’s crust as well as in sea-water and ground-water reservoirs. Therefore, it exerts a great influence on the issues related to life and environment. Vanadium is utilized by several marine organisms. For example, there are vanadate-dependent haloperoxidases in algae and several bacteria, e.g., Azotobacter, use it for nitrogen fixation and bacterial reduction involves the conversion of vanadate to oxidovanadium (IV). The similarity between vanadate and phosphat [...]

by Jun Kohyama

Received: 21 February 2019;  Published: 22 July 2019;  doi: 10.21926/obm.neurobiol.1903034

Background: Several recommendations on optimum sleep duration have been published for adolescents to secure a healthy life. This study aimed to compare the sleep duration of middle and high school pupils in Japan with the recommended values and determined the factors associated with the duration of sleep among them. Methods: A total of 1766 completed questionnaires were obtained from grades 7 to 12 pupils in Japan. The questionnaire addressed the following points: sleeping, eating, defecation, physical activity, sc [...]

by Pierpaolo Di Cocco  , Alberto Fratti  , Kerim B. Kaylan  , Ivo G. Tzvetanov  and Enrico Benedetti

Received: 22 August 2020;  Published: 28 September 2020;  doi: 10.21926/obm.transplant.2003119

This article reviews the current treatment strategies of antibody-mediated rejection in kidney transplantation, which is increasingly recognized as the leading immunological cause of graft failure. The pathophysiologic complexity of this condition poses significant challenges for its treatment; however, progress toward advancing our understanding of its pathogenesis and diagnosis will allow for identification of new therapeutic targets. Emphasis is also given to prevention, which is mainly based on careful assessme [...]

by Anita Verma  and Anil Dhawan

Received: 14 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.transplant.2002108

The infectious complications before and after liver transplant (LT) are affected by the severity of liver disease and immunosuppression intensity after transplantation. Both cirrhosis and immunosuppression contribute to dysfunction of defensive mechanisms of the host. When a patient is evaluated for transplantation, the opportunity arises to assess the individual’s risk for infection and how one may modify those risks through prophylactic and therapeutic strategies. Pretransplant infectious disease evaluation focus [...]

by Alexander Peller  , Lara Suarez  , Ashleigh Trapuzzano  , Matt S. Stock  and Nicole Dawson

Received: 16 November 2021;  Published: 15 February 2022;  doi: 10.21926/obm.geriatr.2201188

Gait speed has been correlated to quality of life and has been called the sixth vital sign. The purpose of this study was to understand the factors that comprise fast and comfortable gait speed. 90 older adults provided demographic, cognitive, and functional performance data. Hierarchical linear regression models revealed predictors for comfortable gait speed to be lower-extremity strength ( B = 1.13, β = 0.233, P< .05), comorbid health ( B = −2.95, β = −0.22, P < 0.05), and gender( B = [...]