by Athalie Redwood-Mills  , Taea Scott  , Mhairi Morris  and Jennifer Wilson

Received: 01 June 2024;  Published: 08 November 2024;  doi: 10.21926/obm.icm.2404066

Chronic diseases, responsible for 74% of global mortality, impose a substantial health burden. This study investigates the perceived effects of CrossFit, a form of functional training, on medication use in the UK population. The research aims to provide insights into how CrossFit might relate to medical interventions for individuals with long-term health conditions. The study, encompassing 1,211 UK residents (over 18yrs.) recruited via CrossFit Affiliates, involved a 14-question online survey covering information p [...]

by Heloísa Maria de Oliveira  , Francisco Alex de Sousa Silva  , Tellys Lins Almeida Barbosa  and Meiry Gláucia Freire Rodrigues

Received: 06 December 2022;  Published: 13 March 2023;  doi: 10.21926/cr.2301012

In an attempt to synthesize nanomaterial concerning chemistry, the sustainable synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) nanoparticles by a low-cost approach through the recycling of waste mother liquors was explored and then indicated the potential to remove chlorhexidine (CHLX) from an aqueous solution. ZIF-8 was produced under solvothermal reaction at 25°C and characterized by Fourier Transform Infrared Spectroscopy, X-ray diffraction, adsorption/desorption of N2, dynamic light scattering and con [...]

by Bas T Röttgering  and Karoly Szuhai

Received: 14 May 2019;  Published: 14 October 2019;  doi: 10.21926/obm.genet.1904096

Insulin-like growth factor 2 (IGF2) is a strong mitogenic peptide with an imprinted gene that is primarily involved in fetal development. It is highly expressed in the fetus where it is involved in fetal growth and tissue differentiation. However, postnatally, the expression of IGF2 decreases despite higher expression levels in the blood as compared with that of IGF1. In adults, the physiological function of IGF2 is poorly understood; however, the possibility of a metabolic function exists. Although the expression [...]

by Khalid Nawaz  , Iqra  , Muneeb Ullah  , Jin-Wook Yoo  , Umme Aiman  , Madiha Ghazanfar  and Muhammad Naeem

Received: 21 June 2024;  Published: 10 January 2025;  doi: 10.21926/rpn.2501002

The persistent inflammation of the intestinal mucosa is the main characteristic of inflammatory bowel disease (IBD), a lifelong illness that affects people of both genders. The exact etiology is still undefined while previously it was attributed to genetic components. Later, it was investigated that the environment has an equal effect on the development of IBD encompassing both Crohn’s disease (CD) and Ulcerative colitis (UC). Among environmental risk factors linked to IBD, diet, notably the transition toward the W [...]

by Anita Verma  and Anil Dhawan

Received: 14 February 2020;  Published: 11 May 2020;  doi: 10.21926/obm.transplant.2002108

The infectious complications before and after liver transplant (LT) are affected by the severity of liver disease and immunosuppression intensity after transplantation. Both cirrhosis and immunosuppression contribute to dysfunction of defensive mechanisms of the host. When a patient is evaluated for transplantation, the opportunity arises to assess the individual’s risk for infection and how one may modify those risks through prophylactic and therapeutic strategies. Pretransplant infectious disease evaluation focus [...]

by Renée J. Zwanenburg  , Trijnie Dijkhuizen  , Martijn J. de Groot  , Sheela Nampoothiri  , Marjolein H. Willemsen  , Eelco Dulfer  , Madhavan V. Thampi  , Nicole de Leeuw  and Conny M.A. van Ravenswaaij-Arts

Received: 13 July 2018;  Published: 21 November 2018;  doi: 10.21926/obm.genet.1804050

Background: Phelan-McDermid syndrome (PMS), or 22q13.3 deletion syndrome, is a neurodevelopmental disorder with an estimated prevalence of 1 in 10,000 to 1 in 20,000 newborns. Although it usually occurs de novo with a low recurrence risk, an increased recurrence risk is observed in some families. In this paper, we provide an overview of the underlying causes of increased recurrence risk in families with PMS and present a workflow aimed at identifying an increased recurrence risk. Methods: First, we report clinical [...]

by Amir Mahboob  , Omid Hassanshahi  , Abdulqaiyoum Hakimi  and Mohammad Safi

Received: 02 March 2023;  Published: 19 April 2023;  doi: 10.21926/rpm.2302016

The largest proportion of the material used in multistory buildings, and thus its carbon impact, is attributed to their slabs being the main contributor of weight. Because of their high strength and concrete self-weight reduction, composite beams with hollow-core slabs were created for their technical and economic benefits, making this system inexpensive and with a reduced environmental impact, thereby lowering carbon emissions. Geometrically, the hollow slab has a sequence of T and L form pieces on both sides. Hol [...]

by Marcel Allbritton  and Carrie Heeter

Received: 30 July 2018;  Published: 09 October 2018;  doi: 10.21926/obm.icm.1804025

We propose a framework for understanding meditation that can support greater scientific rigor in reporting meditation research, and selecting meditation health interventions. There is no consistent and thorough framework for describing meditation research interventions. This impedes rigor of meditation research design and interpretation of findings. This also limits meaningful comparisons across research studies. The audience for this article includes researchers, meditation experts, healthcare professionals, and t [...]

by Estefanía Espina  , José M. Marbán  and Ana I. Maroto

Received: 29 May 2023;  Published: 23 October 2023;  doi: 10.21926/obm.neurobiol.2304191

Dyscalculia is a math learning disability that significantly interferes with students' academic performance and math-related aspects of their daily lives. Early diagnosis and the design of intervention programs adapted to the needs of each case are essential. In this sense, multiple technological resources are created to address both issues. Still, it is difficult to identify which characteristics they share and which are more relevant regarding didactic suitability. Given this situation, this research proposes cat [...]

by Uttayan Chakrabarti  , Manish Chaturvedy  , Nitin Kumar Bajpai  , Jitendra Goswami  , Rajesh Kumar Garsa  and Rajesh Jhorawat

Received: 10 April 2023;  Published: 14 July 2023;  doi: 10.21926/obm.transplant.2303192

BK virus (BKV) is a common opportunistic pathogen in kidney transplant recipients and one of the most challenging causes of allograft dysfunction and loss. Although over-immunosuppression remains the primary risk factor for BKV infection after transplantation, male gender, older recipient age, prior rejection episodes, degree of human leukocyte antigen mismatching, prolonged cold ischemia time, BK virus serostatus and ureteral stent placement have all been implicated as risk factors. Routine screening post-renal tr [...]