by Giuseppe De Benedittis

Received: 18 February 2020;  Published: 24 April 2020;  doi: 10.21926/obm.icm.2002023

There is increasing evidence demonstrating that hypnosis could be effective in the down-modulation of pain sensation in both acute and chronic pain states. In the neurophysiological context, recent evidence has deciphered, to a certain extent, the mystery of pain relief upon hypnosis. It is probable that hypnotic suggestions of analgesia are able to modulate pain processing at multiple levels and sites within the central nervous system (CNS). At the peripheral level, hypnosis may modulate the nociceptive input thro [...]

by Zhong Hu  and Haiping Hong

Received: 21 March 2023;  Published: 16 August 2023;  doi: 10.21926/rpm.2303031

The chemically functionalized carbon nanotubes (f-CNTs) and hydrogen bonding modified polymer composites (CPCs) exhibit unique chemical, mechanical, electrical, and thermal properties and are emerging as promising materials to achieve extraordinarily high electrical and thermal conductivity, lightweight and anticorrosion, superior strength and stiffness for potential applications in the aerospace and automotive industries, energy conversion, and optical and electronic devices, therefore, attracting considerable res [...]

by Heloísa Maria de Oliveira  , Francisco Alex de Sousa Silva  , Tellys Lins Almeida Barbosa  and Meiry Gláucia Freire Rodrigues

Received: 06 December 2022;  Published: 13 March 2023;  doi: 10.21926/cr.2301012

In an attempt to synthesize nanomaterial concerning chemistry, the sustainable synthesis of Zeolitic Imidazolate Framework-8 (ZIF-8) nanoparticles by a low-cost approach through the recycling of waste mother liquors was explored and then indicated the potential to remove chlorhexidine (CHLX) from an aqueous solution. ZIF-8 was produced under solvothermal reaction at 25°C and characterized by Fourier Transform Infrared Spectroscopy, X-ray diffraction, adsorption/desorption of N2, dynamic light scattering and con [...]

by Christin Deal  , Kara Coffey  and Hey Chong

Received: 02 June 2023;  Published: 04 August 2023;  doi: 10.21926/obm.genet.2303190

Newborn screening (NBS) for Severe Combined Immunodeficiency (SCID) has been successfully implemented in all 50 United States and Puerto Rico from 2008-2018. This life-saving screening tool has drastically improved overall survival of babies diagnosed with SCID from 74% to 96%. TREC is a stable, circular DNA molecule that is produced during the process of T-cell receptor (TCR) rearrangement and is the target of the quantitative PCR screen on Guthrie cards. Low TRECs are a marker of low naive T cell numbers. This ne [...]

by Ana Monteagudo-Sánchez  , Marta Sánchez-Delgado  , Sonia Guara Ciurana  , Jose Medrano  , Maria Eugenia Poo-Llanillo  , Miho Ishida  , Gudrun E. Moore  , Isabel Iglesias-Platas  , Carlos Simón  and David Monk

Received: 29 May 2018;  Published: 29 July 2018;  doi: 10.21926/obm.genet.1803026

Background: Symmetrical DNA methylation profiles of autosomal genes are associated with equal expression by both alleles. Genes with an allelic imbalance or monoallelic expression are associated with discrete intervals of allele-specific methylation (ASM), as highlighted by genomic imprinting, X-chromosome inactivation and genotype-driven ASM. However, a more complex pattern has been described in which random monoallelic methylation provides cells with a unique mechanism for modulating allelic dosage. Methods: We c [...]

by Alexander Manevich  , Simon Shimshon Rubin  , Rachel Ben-Hayun  , Judith Aharon-Peretz  and Michael Katz

Received: 07 September 2020;  Published: 12 March 2021;  doi: 10.21926/obm.geriatr.2101160

Caregiving for a loved one suffering from cognitive decline involves coping with many challenges and losses. This experience increases the risk of worsening the physical and mental health of the caregiver and has been the subject of a substantial number of studies focusing on the stress and burden of the primary caretaker. Theory and research on the grief reactions experienced by the family members, however, continues to lag in terms of the attention given to the behavioral and psychological burden of caregivers. T [...]

by Michelle Szucs  , Miguel Angulo  , Carlos Costa  and Mª Carmen Márquez

Received: 12 May 2021;  Published: 08 November 2021;  doi: 10.21926/rpm.2104045

Five different commercial proteases (Alcalase 2.4L, Flavourzyme 1000L, Neutrase, Protamex, and PTN) were evaluated for the simultaneous recovery of protein and lipids through hydrolysis. The hydrolysis reaction was monitored using the pH-stat procedure, in which samples were collected after 240 min of hydrolysis using each enzyme. The samples were analyzed for the degree of hydrolysis, protein hydrolysate, collagen, lipids, and fatty acids. A clear relationship was observed between the degree of hydrolysis and the [...]

by Mubashir Zafar

Received: 13 March 2024;  Published: 24 May 2024;  doi: 10.21926/obm.neurobiol.2402225

The increasing prevalence of mental health issues among university students has become a growing concern globally. This review explores the potential of Artificial Intelligence (AI) integrated with principles of behaviour therapy to address mental health challenges among university students. The paper examines how AI technologies, including chatbots, virtual reality, and machine learning algorithms, can be harnessed to provide accessible, personalized, and effective mental health interventions. Furthermore, it disc [...]

by Uttayan Chakrabarti  , Manish Chaturvedy  , Nitin Kumar Bajpai  , Jitendra Goswami  , Rajesh Kumar Garsa  and Rajesh Jhorawat

Received: 10 April 2023;  Published: 14 July 2023;  doi: 10.21926/obm.transplant.2303192

BK virus (BKV) is a common opportunistic pathogen in kidney transplant recipients and one of the most challenging causes of allograft dysfunction and loss. Although over-immunosuppression remains the primary risk factor for BKV infection after transplantation, male gender, older recipient age, prior rejection episodes, degree of human leukocyte antigen mismatching, prolonged cold ischemia time, BK virus serostatus and ureteral stent placement have all been implicated as risk factors. Routine screening post-renal tr [...]

by Athalie Redwood-Mills  , Taea Scott  , Mhairi Morris  and Jennifer Wilson

Received: 01 June 2024;  Published: 08 November 2024;  doi: 10.21926/obm.icm.2404066

Chronic diseases, responsible for 74% of global mortality, impose a substantial health burden. This study investigates the perceived effects of CrossFit, a form of functional training, on medication use in the UK population. The research aims to provide insights into how CrossFit might relate to medical interventions for individuals with long-term health conditions. The study, encompassing 1,211 UK residents (over 18yrs.) recruited via CrossFit Affiliates, involved a 14-question online survey covering information p [...]