Table of Content

Open Access Original Research

Paranitrophenol and Organic Azo Dye Degradation: Catalytic Power of Terminalia Leaf Silver Nanoparticles

Received: 19 September 2025;  Published: 01 December 2025;  doi: 10.21926/cr.2504010

Abstract

Terminalia species is a widely available plant that can be used to synthesise silver nanoparticles (AgNPs) and harness their catalytic capacity. This experimental design will explore the potential of Terminalia AgNPs in contributing to the degradation process of toxic chemicals generated by industries such as textiles, food, and pharmaceuticals. This research uses four leaf varieties of Terminalia species—T. arjuna, T. bellirica, T. chebula, and T. catappa—to synthesize AgNPs, evaluate their optimal synthesis condi [...]

149 817

Open Access Original Research

Differential Expression of MiR-21 and MiR-19 in Biliary Atresia: Diagnostic Potential and Therapeutic Implications

Received: 24 May 2025;  Published: 26 November 2025;  doi: 10.21926/obm.genet.2504319

Abstract

Biliary atresia (BA), a severe pediatric liver disease of unknown etiology, causes neonatal jaundice, progressive cholestasis, and life-threatening liver fibrosis. Emerging evidence suggests microRNAs (miRNAs) – small non-coding RNAs that regulate gene expression by binding target mRNAs may play a role in BA pathogenesis. Circulating miRNAs have shown diagnostic potential for various diseases, prompting our investigation of miR-21 and miR-19 as potential biomarkers in BA. We conducted a case-control study comparing [...]

204 815

Open Access Original Research

Technology to Help People with Blindness and Intellectual Disability Manage Indoor Travel: Anticipating and Bypassing Obstacles

Received: 18 August 2025;  Published: 27 November 2025;  doi: 10.21926/obm.neurobiol.2504313

Abstract

Recent work with people with blindness and intellectual disability assessed a technology-aided program intended to help eight participants travel indoor routes to reach relevant destinations. The technology included a smartphone, two barcode readers worn by the participants at their ankles, barcodes displayed at specific points of the travel routes, and a mini speaker. The technology ensured that participants received verbal instructions on how to proceed (e.g., take a left turn, cross from one side to the other of [...]

158 793

Open Access Review

Risk Assessment in Clinical Histocompatibility Testing: Challenges, Strategies, and Future Directions

Received: 15 July 2025;  Published: 25 November 2025;  doi: 10.21926/obm.transplant.2504260

Abstract

Though the role of clinical histocompatibility testing is fundamental to successful transplant, systematic risk assessment and mitigation strategies remain underutilised in this domain. This review addresses risk identification, analysis, and control measures across the pre-analytical, analytical, and post-analytical phases of clinical histocompatibility testing, in line with international standards such as ISO 15189:2022. A structured, risk-based quality management system (QMS) is imperative for ensuring accurate [...]

166 778

Open Access Original Research

Environmental Risk Assessment of Antiretrovirals Consumed in Belo Horizonte, Brazil

Received: 09 June 2025;  Published: 04 December 2025;  doi: 10.21926/aeer.2504034

Abstract

The development and utilization of pharmaceuticals, notably antiretrovirals (ARVs), have significantly enhanced both human quality of life and life expectancy. Nevertheless, the excretion of these compounds into aquatic environments, often exacerbated by inadequate sanitation infrastructure, poses considerable risks to biota. This investigation evaluated the environmental impact of 14 ARVs consumed within the municipality of Belo Horizonte (BH), Brazil. The assessment employed the Environmental Risk Assessment (ERA [...]

145 775

Open Access Original Research

Framework for the Secured Integration of Renewable Energy into Power Systems

Received: 11 June 2025;  Published: 05 December 2025;  doi: 10.21926/jept.2504016

Abstract

This research introduces a blockchain framework to improve security and transparency for the use of renewable energy in power systems. The framework utilizes a permissioned blockchain architecture and IoT-based real-time monitoring to ensure data integrity and confidentiality and support efficient peer-to-peer (P2P) energy trading. Compared with traditional centralized energy management systems, the proposed design increases transaction security by 35%, decreases verification wait times by 28%, and decreases the ri [...]

136 759

Open Access Original Research

Effects of Trauma, Shame, and Self-Criticism on Hoarding: Comparative Data and Treatment Implications

Received: 31 January 2025;  Published: 01 December 2025;  doi: 10.21926/obm.icm.2504051

Abstract

Severe trauma has a significant impact on self-attitudes and emotions, such as self-criticism and shame, and psychological symptoms. This topic has been more well studied among populations with Trauma and Stress-Related Disorders, but examined to a lesser extent in other clinical populations where adverse life events and potentially traumatic events are highly prevalent, such as Hoarding Disorder. The current study examined trauma exposure, and the relationships between trauma, self-criticism, shame, and symptom se [...]

208 753

Open Access Commentary

Loneliness, Love and Their Connection: A Commentary

Received: 24 August 2025;  Published: 25 November 2025;  doi: 10.21926/obm.neurobiol.2504312

Abstract

A significant social stigma is associated with loneliness. The prevalence of social isolation, in the dawn of the 21st century points to the growing isolation in America. Lonely people who commonly display negative self-perceptions, show great difficulty to establish social ties, and that may be related to their personal inadequacies, or socially undesirable attributes. Lonely people suffer from a low social perception, painting them as less psychologically adjusted, and not very capable in relating to others. That [...]

155 698

Open Access Original Research

GHG Emissions Management in Urban Areas by Interactive Road Traffic Control: Application of Artificial Intelligence

Received: 04 June 2025;  Published: 03 December 2025;  doi: 10.21926/aeer.2504033

Abstract

The rising pollution levels in congested urban areas pose a serious threat to human health. Many solutions have been proposed to control and reduce gas emissions from road traffic, with results that are not entirely satisfactory. The adoption of new techniques and methodologies for early detection of pollutant emissions may enable effective management and control of road traffic contamination. The proposed method introduces an interactive protocol that facilitates communication between the traffic control center an [...]

110 637

Open Access Original Research

The Value of Camellia sinensis in the Management of Toxicity Induced by Cancer Treatments

Received: 17 June 2025;  Published: 02 December 2025;  doi: 10.21926/obm.icm.2504052

Abstract

While radiotherapy is one of the main treatments for head and neck cancer, adverse effects limit its effectiveness and affect patients' quality of life. Although various radioprotective substances have been proposed, comprehensive strategies are needed to modulate radiotoxicity. In this regard, compounds from green tea (Camellia sinensis), with antioxidant, anti-inflammatory, and antiproliferative properties, could be suitable for optimizing the radiotherapy relationship. A descriptive, prospective study was conduc [...]

124 627

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