Table of Content

Open Access Original Research

Associations between Health-Related Behaviours, Well-Being, and Academic Performance of Secondary School Students with Special Educational Need: A Secondary Analysis

Received: 24 October 2022;  Published: 06 March 2023;  doi: 10.21926/rpn.2301005

Abstract

Health-related behaviours (HRBs) have been considered one of the most critical public health issues, especially for those with special educational needs (SEN). Previous research suggests that health-related behaviours are highly likely to impact well-being and academic achievement. Diet is a crucial health-related behaviour that needs to be investigated along with factors such as sleep and exercise. The present study used data from the Cornish Academies Project, and secondary analyses were conducted to investigate [...]

1254 8952

Open Access Comment

Clinical, Theoretical and Conceptual Issues in Chronic Pain and Their Application in a Hypnosis Practice

Received: 01 July 2019;  Published: 26 September 2019;  doi: 10.21926/obm.icm.1903057

Abstract

Hypnosis interventions consistently produce significant decreases in pain associated with a variety of chronic-pain problems (Elkins, Jensen & Patterson 2007) while neurophysiological studies have shown that specific hypnotic suggestions have clear effects on the brain and spinal cord functioning (Jensen & Patterson 2014; Flynn, 2019). Thus, it isuseful for clinicians who practise hypnotherapy to understand pain paradigms.

1986 8950

Open Access Original Research

Cisplatin-Based Neoadjuvant Chemotherapy for Elderly Patients with Muscle-Invasive Bladder Cancer: Is It Feasible?

Received: 23 July 2021;  Published: 08 November 2021;  doi: 10.21926/obm.geriatr.2104183

Abstract

Cisplatin-based neoadjuvant chemotherapy (C-NAC) has been the standard of care in localized muscle-invasive bladder cancer (MIBC). However, the feasibility and benefit of C-NAC in elderly patients remain uncertain since this population has always been underrepresented in pivotal trials and is often barred from chemotherapy in routine practice because of their perceived frailty. Therefore, in order to evaluate the effectiveness of C-NAC in elderly patients with MIBS, we retrospectively reviewed the medical files of [...]

1108 8946

Open Access Original Research

The P2X7 Receptor Antagonist AZ10606120 Does Not Alter Graft-Versus-Host Disease Development and Increases Serum Human Interferon-γ in a Humanized Mouse Model

Received: 06 June 2022;  Published: 06 September 2022;  doi: 10.21926/obm.transplant.2203166

Abstract

Allogeneic hematopoietic stem cell transplantation is a curative therapy for hematological malignancies, but its efficacy is limited by graft-versus-host disease (GVHD). This life-threatening disorder develops when donor (graft) immune cells cause inflammatory damage to recipient (host) tissues. The immune cell receptor channel P2X7 and its ligand adenosine 5’-triphosphate (ATP) have been implicated in GVHD pathogenesis. Therefore, this signaling axis represents a potential therapeutic target. This study aime [...]

1180 8944

Open Access Case Report

Efficacy of Autologous Stem Cell Transplantation for the Treatment of Multiple Myeloma in HIV-Positive Patients

Received: 12 April 2021;  Published: 09 July 2021;  doi: 10.21926/obm.transplant.2103148

Abstract

Prior to the advent of anti-retroviral therapy (ART), autologous stem cell transplant (ASCT) was relatively contraindicated for multiple myeloma (MM) patients with human immunodeficiency virus (HIV) due to issues associated with stem cell harvest and the risk of opportunistic infections. With the widespread use of ART for control of HIV, ASCT is now the preferred treatment for relapsed lymphoma, the leading hematopoietic malignancy associated with HIV/AIDS. Hence, MM patients with HIV controlled by ART may benefit [...]

1535 8943

Open Access Original Research

Influence of Recycled Concrete Aggregate Type on Rheological Behaviour of Mixtures Proportioned Using the Equivalent Volume Method

Received: 11 July 2022;  Published: 07 September 2022;  doi: 10.21926/rpm.2203017

Abstract

The ever-growing urgency to combat climate change has led the civil construction industry to develop and adopt sustainable construction materials and methods. The so-called recycled concrete aggregate (RCA) emerges as an alternative to decrease the carbon footprint of new concrete construction, the disposal of waste concrete, and the use of non-renewable natural resources such as cement and aggregates. RCA can be produced from crushing waste concrete; yet challenges remain when using RCA in concrete especially its [...]

1326 8941

Open Access Review

Evaluating the Efficacy of Action Observation Training in Improving Upper Limb Functionality in Children with Cerebral Palsy: A Scope Review

Received: 02 June 2024;  Published: 22 November 2024;  doi: 10.21926/obm.neurobiol.2404257

Abstract

This review evaluates the efficacy of Action Observation Training (AOT) in improving upper limb functionality in children with cerebral palsy (CP). Five studies were selected based on strict inclusion criteria, focusing on clinical interventions that assessed AOT's effects on upper limb motor skills in pediatric CP populations. Across these studies, significant improvements were observed in motor skills such as reach, grasp, and spontaneous use of the affected limb, underscoring AOT's potential functional benefits. [...]

996 8926

Open Access Original Research

Fischer-Tropsch Synthesis on Co/SBA-15 Catalyst: Characterization and Oligomerization Modeling

Received: 05 May 2022;  Published: 16 August 2022;  doi: 10.21926/cr.2203023

Abstract

In this study, we investigated the oligomerization mechanism of the Fischer-Tropsch synthesis catalyzed by a cobalt-based catalyst supported by SBA-15. The Co/SBA-15 catalyst contained 20% w/w of cobalt. It was prepared by the wet impregnation method and characterized by X-ray diffraction (XRD), N2 adsorption-desorption, temperature-programmed reduction (TPR), and scanning electron microscopy coupled to X-ray energy dispersion spectroscopy (SEM-EDS). The FT synthesis was conducted in a slurry bed reactor operating [...]

1718 8917

Open Access Review

Systematic Review of High-Dimensional Omics in Mind-Body Medicine

Received: 27 March 2022;  Published: 05 December 2022;  doi: 10.21926/obm.icm.2204052

Abstract

The multi-dimensional measurement of complex biological systems and sub-systems is made possible by high-dimensional omics technologies. This frontier of research is promising for elucidating disease processes, physiological parameters, and therapeutic action mechanisms. Omics have potential merit for the integrative medicine field that is relatively early in terms of mechanistic research towards understanding the underlining therapeutic processes of mind-body interventions that show to affect multiple systems simu [...]

1473 8916

Open Access Review

Perspective on Neurobiological and Clinical Early Indicators of Mild Cognitive Decline and Alzheimer’s Disease

Received: 17 April 2017;  Published: 09 July 2017;  doi: 10.21926/obm.neurobiol.1702006

Abstract

There is a need for early diagnosis, monitoring and treatment of Alzheimer’s Disease (AD) and Mild Cognitive Impairment (MCI). Traditional assessments of cognitive decline have been found to lack sensitivity and accuracy in differentiating varying stages of Dementia and cognitive decline as well as being time consuming in their administration. Key components of cognition namely memory and executive function have been identified as most predicative of AD status. Brief cognitive screening tools such as the Montreal C [...]

1668 8915

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