Table of Content

Open Access Review

The Role of Self-Compassion in Recovery from Substance Use Disorders

Received: 04 March 2019;  Published: 24 April 2019;  doi: 10.21926/obm.icm.1902026

Abstract

Background: A large body of empirical evidence has supported the notion that individuals with substance use disorders (SUDs) have difficulty regulating their negative emotions and employing emotion-regulation strategies. The aim of this article is to (a) explore the role of self-compassion in providing an emotion-regulation strategy for initiating a process of recovery from SUDs; (b) examine the role of self-compassion in building recovery capital (RC) to promote long-term recovery; and (c) examine the practice of [...]

4754 28197

Open Access Review

The Role of Mitochondria in Oocyte and Early Embryo Health

Received: 01 January 2019;  Published: 29 March 2019;  doi: 10.21926/obm.genet.1901070

Abstract

The mitochondria of the oocyte are a prominent source of energy metabolism as well as mitochondrial DNA that will later populate the cells of the offspring. Recent discoveries provided new insight into the physiology of the mitochondria and its unique genetics. The concept of heteroplasmy defined as the presence of more than one type of mitochondrial genome, is gaining increasing recognition as an important contributor to several complex morbidities, age-related reproductive dysfunction and aging. Understanding the [...]

2753 28178

Open Access Review

Development of Low Elastic Modulus Titanium Alloys as Implant Biomaterials

Received: 20 March 2022;  Published: 21 April 2022;  doi: 10.21926/rpm.2202008

Abstract

Biomaterials have always been the focus of material scientists and engineers. Titanium and its alloys have favorable properties, such as high strength, low density, good corrosion resistance, non-toxicity, low elastic modulus, biocompatibility, etc. Thus, Ti alloys have received much attention from scientists and engineers who work with biomaterials. Among these properties, the elastic modulus is a very important property for implant biomaterials because it avoids the “stress shielding” effect. In this study, we su [...]

4417 27845

Open Access Review

Challenges and Opportunities of Gene Therapy in Cancer

Received: 07 October 2023;  Published: 04 March 2024;  doi: 10.21926/obm.genet.2401219

Abstract

Gene therapy involves either the direct introduction of genetic material (DNA or RNA) into the host cell (or organ), known as in vivo gene therapy, the re-introduction of the modified target cells taken out of the host, or ex vivo gene therapy. Cancer is mainly caused by the non-functioning of genes required for normal cell proliferation, and it has emerged as the leading cause of death globally due to the absence of efficient and safe therapies as well as early diagnostic modalities. Therapeutic trials using gene [...]

2534 27599

Open Access Review

Neonatal Hypoxic Ischemic Encephalopathy: An Updated Preclinical and Clinical Review

Received: 04 February 2020;  Published: 28 July 2020;  doi: 10.21926/obm.neurobiol.2003068

Abstract

Hypoxic-ischemic encephalopathy is a major cause of death and disability in the newborn period. Experimental models have demonstrated that brain injury in hypoxic-ischemic encephalopathy occurs in two phases: primary energy failure and secondary energy failure. In primary energy failure, there is a cessation of oxidative metabolism and irreversible neuronal injury, followed by secondary energy failure due to glutamate release, elevation of intracellular calcium, reactive oxygen species formation, apoptotic cell dea [...]

2532 27552

Open Access Original Research

The Impact of Breakfast Omission on Daily Activities and Academic Achievement: A Cross-Sectional Study at Fazaia Ruth Pfau Medical College

Received: 04 April 2024;  Published: 27 September 2024;  doi: 10.21926/rpn.2403016

Abstract

Breakfast omission can essentially impact daily activities and academic performance, leading to diminished energy, poor concentration, mood disturbances, and potentially lower academic accomplishment. Advancing the significance of a nutritious breakfast and ensuring access to such meals is crucial for physical and cognitive prosperity. Examine the effect of breakfast exclusion on daily activities and insightful achievement in specific people. This study intends to evaluate the potential significance of findings in [...]

6029 27539

Open Access Research Article

Gluten-Free Diet for the Treatment of ADHD; Pilot Study

Received: 17 December 2018;  Published: 03 April 2019;  doi: 10.21926/obm.neurobiol.1902024

Abstract

Background: The association between Attention Deficit Hyperactivity Disorder (ADHD) and celiac disease has already been established. Non-celiac gluten sensitivity (NCGS), as well as celiac disease, has been associated with neuro-psychiatric disorders. Our objective is to assess if a proportion of pediatric ADHD patients are affected by NCGS and could consequently benefit from a gluten-free diet. Methods: Pilot study of 6 ADHD patients. Personal or family history suggestive of NCGS was investigated. The Conners Cont [...]

2277 27277

Open Access Original Research

The Impact of Physical Activity on Brain Neuroplasticity, Cognitive Functions and Motor Skills

Received: 20 December 2023;  Published: 25 April 2024;  doi: 10.21926/obm.neurobiol.2402219

Abstract

The research aims to study the mechanisms and factors contributing to brain neuroplasticity. To achieve this goal, the following methods were used: analysis and synthesis, hermeneutic method, psychological testing, and comparative and generalization methods. The research results revealed the nature of the concept of brain neuroplasticity and types of neuroplasticity, analyzed the process of redistribution of brain functions, determined the role of compensatory plasticity, revealed methods of studying brain neuropla [...]

1703 27220

Open Access Original Research

Energy Efficiency of High-Speed Railways

Received: 18 August 2022;  Published: 26 December 2022;  doi: 10.21926/aeer.2204055

Abstract

The world is becoming more dependent on energy resources, which translates into political dependency on energy-exported states. This will significantly impact the economy, transport, and the environment around the world. Railway transport is becoming an essential mode of transportation because it can operate on an electrified network and has zero carbon emissions. High-Speed Railways (HSR) is an energy-intensive transport system, and it is important economically and environmentally to reduce the amount of used ener [...]

5518 27168

Open Access Review

Molecular Marker Analysis of Genetic Diversity in Maize: A Review

Received: 25 July 2021;  Published: 21 March 2022;  doi: 10.21926/obm.genet.2201150

Abstract

Maize is consumed as a food and used as an industrial product in the form of starch, pharmaceuticals, alcoholic beverages, oil, cosmetics, and textiles. In ancient times, landraces were more popular due to the presence of high genetic variability, resistance to biotic and abiotic factors, and the heterogeneous nature of maize; however, it has been replaced by improved and uniform cultivars with a higher yield. Modern maize has more homogeneity that enhances its vulnerability to biotic and abiotic stresses. Thus, we [...]

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