by David Smithard  , Signe Westmark  and Dorte Melgaard

Received: 15 September 2019;  Published: 15 November 2019;  doi: 10.21926/obm.geriatr.1904086

Background: With the increasing age of the world population, the number of old and frail people is increasing. Respiratory disease is a common reason for hospital admission for older people. Aspiration of saliva, which is probably infected, is the likely etiological agent. The incidence of an abnormal swallow is high in frail older people. Despite the high incidence of swallow problems among older people, many hospital services do not routinely screen older people for dysphagia. Methods: A survey, using Research El [...]

by Joshua A Vova

Received: 21 February 2022;  Published: 20 April 2022;  doi: 10.21926/obm.neurobiol.2202120

Cerebral Palsy (CP) is the most frequent cause of childhood disability. CP occurs in 1 out of every 345 children in the United States. CP is primarily a motor disease that is the result of an insult to the brain that occurs during the prenatal or early postnatal period when the brain is still developing. CP is not a single disease but a physical description of motor impairments that originate from multiple etiologies. This article briefly discusses the etiologies, classification and management of the neurologic med [...]

by Nikolai A. Zarkevich

Received: 30 September 2019;  Published: 06 January 2020;  doi: 10.21926/jept.2001001

Most power plants produce electricity by converting a mechanical motion into alternating current (AC). Photovoltaic solar panels convert an electromagnetic flux of light into direct current (DC). In general, electric energy can be harvested from a flux in the environment or from a change of the environment itself. One can produce electricity from mechanical, chemical, thermal, electromagnetic (light), or another physical flux, or from a change of temperature, chemical composition, or a physical field: gravitationa [...]

by Mykhailo Zhylin  , Viktoriia Mendelo  , Svitlana Bondarevych  , Yuliia Kokorina  and Andrii Tatianchykov

Received: 08 July 2024;  Published: 22 November 2024;  doi: 10.21926/obm.neurobiol.2404256

Emotional regulation (ER) is the process by which people change their physiology, expressions, and emotional experiences to operate in their daily lives. Deficits in emotion control may be connected to physical and mental health consequences. This review aims to identify genetic variants, understand neurobiological mechanisms, and explore behavioral phenotypes associated with ER. In our study, we included English studies from online databases such as Web of Science, Cochrane Library, Google Scholar, PubMed, and Sco [...]

by Nicole A. Bailey  and Laura Mackay

Received: 12 May 2024;  Published: 16 August 2024;  doi: 10.21926/obm.genet.2403256

Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism with an incidence that varies throughout the world. PKU is caused by loss of function variants in the phenylalanine hydroxylase gene. This loss of function leads to the accumulation of an amino acid, phenylalanine (Phe), that can reach toxic levels in the blood. PKU is managed with a medical diet and sometimes with medication. If diagnosed early and with strict dietary control, neurocognitive deficits can be prevented. There is an important [...]

by Wisut Chamsa-ard  , Derek Fawcett  , Chun Che Fung  and Gerrard Poinern

Received: 28 September 2020;  Published: 29 December 2020;  doi: 10.21926/jept.2004018

The demand for high-quality freshwater is increasing due to global population growth, intensifying agricultural practices and expanding industrial development. Additionally, many global regions have low levels of rainfall which makes them arid and incapable of supporting large human populations or agriculture. Currently, large quantities of fossil fuels are used to generate the power needed to drive energy intensive desalination processes that deliver high-quality freshwater to many of these regions. However, the u [...]

by Richard B. Kreider

Received: 01 April 2021;  Published: 03 November 2021;  doi: 10.21926/obm.icm.2104041

Obesity has historically been thought to simply be related to an imbalance between energy intake and expenditure. Weight loss recommendations have traditionally focused on reducing energy intake, maintaining either a high-carbohydrate low-fat diet or vice versa, and increasing physical activity typically through low to moderate intensity exercise. More recently, genetic, physiological, and behavioral factors have also been found to play a significant role in the etiology of obesity. For this reason, the prevention [...]

by Suheir Awadalla  , E Bethan Davies  and Cris Glazebrook

Received: 21 October 2024;  Published: 31 December 2024;  doi: 10.21926/obm.neurobiol.2404261

Numerous studies have explored the prevalence of depression and anxiety symptoms among university students worldwide. However, only a few have examined how these symptoms affect students' academic performance. This systematic review explores the relationship between depression, anxiety, and academic performance among undergraduate university students. Peer-reviewed articles published between 1997 and June 2020 were included if they: (a) were in English; (b) had a study population that was exclusively undergraduate [...]

by Behzad Foroutan

Received: 02 January 2023;  Published: 03 July 2023;  doi: 10.21926/obm.genet.2303185

The main purpose of this paper was to generate a narrative review related to the current knowledge of the TP53 gene and its product, the p53 protein. It was also attempted to elucidate the different p53 reactivation strategies of great interest, as various small molecules are being studied to reactivate mutant p53. PubMed and ScienceDirect were searched for p53, mutant p53, and wild-type p53 limited by the title filter through the end of 2022. The collected articles were studied, evaluated and summarized. In the sh [...]

by Kenneth Ugoeze  , Christian Alalor  , Chidozie Ibezim  , Bruno Chinko  , Peter Owonaro  , Clement Anie  , Ngozi Okoronkwo  , Amaka Mgbahurike  , Chijioke Ofomata  , Deghinmotei Alfred-Ugbenbo  and Geraldine Ndukwu

Received: 22 September 2023;  Published: 22 January 2024;  doi: 10.21926/aeer.2401005

The discovery of antibiotics and their use in the last century substantially shifted the management of an array of infections. However, its unprecedented irrational usage and inept disposal of their waste exposed the ecosystems to unquantifiable antibiotic deposits, triggering the emergence of antimicrobial resistance (AMR) with its immeasurable critical risk to public health. By adopting a narrative review method and accessing the available literature, the authors described what constitutes antibiotic waste, their [...]