by Sarah-Catherine Rodan  , Phillip Aouad  , Iain S McGregor  and Sarah Maguire

Received: 08 April 2021;  Published: 24 June 2021;  doi: 10.21926/obm.neurobiol.2102102

Anorexia Nervosa (AN) is a major health problem with one of the highest mortalities and treatment costs of any psychiatric condition. Cognitive behavioural therapy (CBT) is currently the most widely used treatment for AN in adults but provides remission rates ≤ 50%. Treatment drop-out is exceedingly high and those that persevere with treatment often relapse, causing increased risk of morbidity and mortality. There is an urgent need to find new interventions, especially as there are no approved pharmacological treat [...]

by Kate McKeown  , Emma Richards  , Jessica Richardson  and Andrea Tales

Received: 08 January 2021;  Published: 07 June 2021;  doi: 10.21926/obm.neurobiol.2102100

Information processing speed (Reaction time, RT) to a single administration of the Trails A and Trails B components of the Trail Making Test (TMT) is used in the assessment of brain and behavioural functional integrity across the lifespan in both clinical and research contexts. Although the clinical utility of such single trial-related and thus rapidly gained results, is recognised, it is possible that its administration as a single trial only, precludes its ability to provide a more in-depth and thus relevant repr [...]

by Paul A. Barclay  and Clint A. Bowers

Received: 27 July 2018;  Published: 07 October 2018;  doi: 10.21926/obm.icm.1804024

(1) Background: Meditation is a common intervention for college students suffering from issues with anxiety. Due to this popularity, several meditation-based video games have been released which can be used to supplement or motivate meditation practice. However, these tools are not often given scrutiny in a laboratory setting before being released to the public. Our lab conducted a brief feasibility pilot study to investigate Meditation Deathmatch, an open-source meditation video game aimed at stimulating meditatio [...]

by Remedios Martinez-Guijarro  , Maria Pachés  , Inmaculada Romero  and Daniel Aguado

Received: 08 October 2021;  Published: 15 December 2021;  doi: 10.21926/aeer.2104033

Heavy metal(loid)s are a group of elements present commonly in the environment, including Cr, Ni, Cu, Zn, Cd, Hg, Pb, and As elements, among others. While these elements could have their origins in natural sources, anthropogenic activities, such as mining, agriculture, industry, etc., are also responsible for enhancing the concentration of these elements in the ecosystems up to undesirable levels. A few of these metal(loid)s serve as necessary micronutrients for life, while the others are extremely harmful and migh [...]

by Igor Val Danilov

Received: 20 June 2023;  Published: 05 October 2023;  doi: 10.21926/obm.neurobiol.2304185

The theoretical article aims to develop knowledge about the modulation of shared intentionality at the cellular level. A hypothesis about the neurobiological processes during shared intentionality argues that this pre-perceptual communication occurs through nonlocal neuronal coupling in an ecosystem that can be described as the mother-fetus communication model. The current theoretical study analyses literature to discuss recent findings on the effect of oscillations on neuronal temporal coordination to verify wheth [...]

by Trevor R Norman

Received: 07 February 2021;  Published: 14 October 2021;  doi: 10.21926/obm.neurobiol.2104108

Depression in the elderly is a significant clinical problem which is likely to endure as an ongoing issue as the cohort of individuals aged over 65years continues to increase as a proportion of the total population. While there are a multiplicity of approaches to the treatment of depression, the mainstay for moderate to severe cases is pharmacotherapy. The majority of extant antidepressants have demonstrated efficacy, at least in short term (6-12weeks) clinical evaluations. There is demonstrable efficacy over and a [...]

by Kenneth Ugoeze  , Christian Alalor  , Chidozie Ibezim  , Bruno Chinko  , Peter Owonaro  , Clement Anie  , Ngozi Okoronkwo  , Amaka Mgbahurike  , Chijioke Ofomata  , Deghinmotei Alfred-Ugbenbo  and Geraldine Ndukwu

Received: 22 September 2023;  Published: 22 January 2024;  doi: 10.21926/aeer.2401005

The discovery of antibiotics and their use in the last century substantially shifted the management of an array of infections. However, its unprecedented irrational usage and inept disposal of their waste exposed the ecosystems to unquantifiable antibiotic deposits, triggering the emergence of antimicrobial resistance (AMR) with its immeasurable critical risk to public health. By adopting a narrative review method and accessing the available literature, the authors described what constitutes antibiotic waste, their [...]

by Garuth Chalfont  , Jane Simpson  , Sarah Davies  , David Morris  , Ruth Wilde  , Leigh Willoughby  and Christine Milligan

Received: 08 April 2019;  Published: 07 August 2019;  doi: 10.21926/obm.geriatr.1903066

The dominant narrative around dementia argues that progression cannot be halted or reversed. However, evidence on multimodal non-pharmacological treatments formulated around a ‘personalised medicine’ approach challenges this view. This paper reviews the current evidence for dementia prevention utilising such treatments and explains the logic of applying personalised medicine. The functional medicine treatment approach to ‘root cause’ analysis is presented as currently practiced with patients experiencing cognitive [...]

by Babak Jahani  , Xinnan Wang  and Amanda Brooks

Received: 26 June 2020;  Published: 08 September 2020;  doi: 10.21926/rpm.2003021

Bone tissue engineering (BTE) as a modern and more effective treatment for bone defects has recently received lots of attention. One of the pivotal parts of BTE is the “scaffold”, which functions as an indwelling carrier of cells and additives, as well as, providing a foundation for cell growth and eventually forming new, native-like bone. Up to now, many methods and materials have been employed to manufacture bone scaffolds. This review focuses on providing both basic knowledge of BTE as well as possible methods o [...]

by Maurizio Arena  and Claudia Aprea

Received: 16 December 2020;  Published: 22 February 2021;  doi: 10.21926/aeer.2101002

The current situation of the COVID-19 pandemic has led to multiple changes in the international market as well as in the lifestyle of people worldwide. The transport sector has undoubtedly been one of the most affected sectors due to restrictions imposed by the governments across the world to protect the health of their citizens, particularly the restrictions imposed on the operation of airlines. On the other hand, the reduction in travel by means of transport has contributed in part to the improvement in the envir [...]