Overview of Newborn Screening of Lysosomal Storage Diseases for Pediatric Care Providers
Abstract
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Overview of Newborn Screening of Lysosomal Storage Diseases for Pediatric Care ProvidersAbstract
Lysosomal storage disorders (LSD) are caused by enzymatic failure to degrade specific cellular byproducts of metabolism within the lysosome. They have a wide range of presentations involving multiple body systems and can manifest from infancy through adulthood. As treatments have become available for many of these disorders, newborn screening has been adapted for early identification and pre-symptomatic treatment. This article will review some of the LSD that are now being added to newborn screening panels, includi [...] 1168 10567 |
Advances in Quantum Properties of Graphene and Derivatives Applied to Functional Nanomaterials and MetamaterialsAbstract
In the present work we describe the most important quantum properties of graphene and derivatives recently published. We discuss how these properties were incorporated into varied hybrid materials such as substrates for specific tuning of matter to track varied quantum signals. Their potential applications were analyzed from nanomaterial and nanotechnology. In particular graphene, its derivatives and other carbon-based allotropes were chosen due to their special chemical structure and properties from the nanoscale [...] 1474 10567 |
Internet Mindfulness Meditation Intervention (IMMI) Program with iMINDr Application Support for Older Adults with Depression Symptoms: A Feasibility StudyAbstract
The growing population of older adults with depression is a significant public health concern, and effective treatments are necessary. Mindfulness meditation intervention offers effective treatment for depression, but little research has been conducted on the older population. This study aimed to evaluate if the combination of the Internet Mindfulness Meditation Intervention (IMMI) plus iMINDr application improves well-being in older adults with depressive symptoms. Potential participants were recruited online. IMM [...] 1414 10552 |
Environmental Impacts of Different Electricity Production Scenarios in FranceAbstract
This study focuses on the environmental impacts of the electricity production scenarios proposed for France for 2060 by the French electricity network manager, RTE. They consider an increasing electricity consumption and a production without fossil fuels, essentially based on wind, photovoltaic, hydraulic, and, for some, nuclear power. The total power to install is significantly higher than the current one; it is higher in the scenarios that rely more on photovoltaic and less on nuclear. Renewable energies require [...] 1172 10549 |
Review of the Nutritional Status in Older Adult Populationby
Abstract
The leading causes of death in older adults involve nutritional risk factors, heart disease, cancer, stroke and diabetes. Prevalence of lifestyle diseases, older adults consider themselves in good, very good or excellent health. Older adults want to remain independent and not burden others; they believe proper nutrition and sufficient exercise will help them maintain their autonomy and independence. To describe the diet, nutrition and general health status of the older adult population in Spain and their adherence [...] 1403 10547 |
Cortical Activity and Rhythmic Patterns in Mouse Models of Aging and Alzheimer’s DiseaseAbstract
Aging and Alzheimer’s disease (AD) have been reported to induce changes in the cerebral cortex circuits. The present review aims to study these alterations by reviewing emergent cortical activity with a focus on the rhythmic patterns. The rationale for this approach was two-fold: (i) emergent rhythmic activity integrates cellular and network properties of these underlying circuits; and (ii) alterations in rhythmic patterns reflect the functional impact of changes on the network induced by the pathophysiology of the [...] 1382 10546 |
Poly (Lactic Acid) (PLA)/Recycled Styrene Butadiene Rubber (rSBR) Compositesby
Abstract
Recycled styrene butadiene rubber (rSBR) from waste car tires was used as a filler in poly(lactic) acid (PLA) to modify its properties. The compounds were prepared via twin-screw extrusion and molded by injection with different rSBR contents (0 to 25% wt.). Additionally, recycled rubber particle size was controlled between 125 and 1000 μm to determine the effect of this parameter. From the samples produced, a series of morphological, physical and mechanical characterizations were performed. As expected, rSBR additi [...] 1610 10545 |
A Multi-modal Intervention after Stroke: The Caregiver Experienceby
Abstract
Background: A fall prevention intervention was delivered to people with chronic stroke (Merged Yoga and Occupational Therapy intervention-MY-OT). All caregivers were invited to also attend the 8-week intervention and were included in these analyses. Methods: The aim of this study was to examine changes in caregiver burden, positive aspects of caring, and caregiver's experiences after participating in the MY-OT intervention. This was a secondary data analyses and the purpose of this mixed-methods study was to quanti [...] 1993 10536 |
The Drag Forces on a Taylor Bubble Rising Steadily in Vertical PipesAbstract
By the adoption of a drag-buoyancy equality model, analytical solutions were obtained for the drag coefficients (CD) of Taylor bubbles rising steadily in pipes. The obtained solutions were functions of the geometry of the Taylor bubble and the gas volume fraction. The solutions were applicable at a wide range of Capillary numbers. The solution was validated by comparison with experimental data of other investigators. All derived drag formulas were subject to the condition that Bond number >4, for air-water syste [...] 1905 10536 |
Parting with the Concept of Alzheimer’s Disease in Seniumby
Abstract
The understanding of mental deterioration associated with old age has undergone several changes over the past two centuries, and has spurred major scientific debates. In the 19th century, this disorder was still considered an inevitable part of aging. The beginning of the 20th century offered a histological explanation for presenile dementia, and Alois Alzheimer was credited as the discoverer of a new disease that bears his name to date. In the last quarter of the 20th century, findings of Alois Alzheimer were appl [...] 1619 10535 |
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