by Carly M. Darden  , Srividya Vasu  , Kenjiro Kumano  , Bashoo Naziruddin  and Michael C. Lawrence

Received: 21 November 2018;  Published: 29 January 2019;  doi: 10.21926/obm.transplant.1901043

Islet transplantation is a minimally invasive cell based replacement therapy to prevent or reverse diabetes or hypoglycemia through natural hormonal responses to regulate blood glucose. However, extending the islet graft functional lifespan remains a challenge that prevents long-term success and widespread use of the procedure. Islets are subject to stress and damage and undergo immunological assault during transplantation procedures. Current treatments to prevent immune reactivity toward the graft come with toxic [...]

by Christine Demanche  , Jacques Guillot  and Magali Chabé

Received: 22 February 2019;  Published: 15 May 2019;  doi: 10.21926/obm.genet.1902078

Pneumocystis spp. are a group of fungi that are known for causing opportunistic infections in immunocompromised individuals. It was only at the end of the 20th century that the scientific community challenged the notion of a unique species in the genus Pneumocystis (i.e., Pneumocystis carinii) that drastically changed the understanding of the natural history of pneumocystosis. It is now accepted that the Pneumocystis genus comprises a group of heterogenous fungi having multiple stenoxenic biological entities. These [...]

by Huda Jamal Jumaah  , Mohammed Hashim Ameen  and Bahareh Kalantar

Received: 31 August 2022;  Published: 12 January 2023;  doi: 10.21926/aeer.2301006

Iraq’s lakes and rivers are currently exposed to drought because of climatic and political conditions. This study uses satellite images and geographic information systems to display the water depletion and the change in the surface water area of Hamrin Lake. Sentinel-2 imagery of 2018 and 2022 was used to analyze the surface water area changes and water depletion. A comparison was made by studying the changes that happened between 2018 and 2022 respectively. Moreover, a supervised classification technique was [...]

by Alex T. Von Schulze  , Marie van der Merwe  , Chad D. Touchberry  and Richard J. Bloomer

Received: 03 August 2021;  Published: 15 October 2021;  doi: 10.21926/rpn.2104001

Poor dietary habits can lead to obesity and insulin resistance—both of which can impair basal heat shock protein (HSP) expression and the HSP stress response in skeletal muscle. It remains unclear if impairments in HSP expression occur during the early stages of diet-induced obesity and metabolic dysfunction. We determined if basal HSP expression (HSP70, HSP60, HSP25) was impaired in sedentary or exercised rats following the onset of diet-induced obesity. Male Long-Evans rats (N=6-7/group) were assigned to a [...]

by Barbara Schmidt  , Teresa Deffner  and Jenny Rosendahl

Received: 11 December 2019;  Published: 28 April 2020;  doi: 10.21926/obm.icm.2002025

Patients in the intensive care unit are confronted with an extreme situation that may cause stress and anxiety. The negative experiences may cause patients to suffer for the long-term after leaving the intensive care unit. One such stressor in the intensive care unit is non-invasive ventilation. Positive therapeutic suggestions under hypnosis can help patients in intensive care to enhance their well-being by helping them to deal with specific stress like being ventilated. The aim of our study is to assess the effec [...]

by Mahyar Vefaghi  , Hediyeh Rezaei Sedehi  and Omid Ashkani

Received: 09 April 2025;  Published: 03 August 2025;  doi: 10.21926/rpm.2503012

Nowadays, the development of advanced processors plays a key role in the progress of humanity and the discovery of new sciences, and quantum computers play an essential role in this regard. In this regard, the development of new generation processors is necessary for the development of quantum computers. Quantum diamonds, with their astonishing properties, especially the presence of nitrogen-vacancy (NV) centers in their crystalline structure, are among the most advanced emerging technologies in the field of quantu [...]

by Makeda L. Robinson  , Kyle Enriquez  and Dora Y. Ho

Received: 02 November 2018;  Published: 08 January 2019;  doi: 10.21926/obm.transplant.1901038

Flaviviruses can cause epidemics and endemics with substantial public health threat and economic impacts. In the last few decades, many flaviviruses have re-emerged or expanded their territories to new regions or continents, including West Nile virus (WNV) which has become endemic in the US since its arrival in 1999 and Zika virus (ZIKV) which recently spread across the Americas. These events demonstrate the speed with which a vector-borne pathogen can disseminate when introduced into a susceptible population with [...]

by Nuria Arias-Ramos  , Jesús Pacheco-Torres  and Pilar López-Larrubia

Received: 11 November 2018;  Published: 30 January 2019;  doi: 10.21926/obm.neurobiol.1901020

Background: Despite important advances in multimodal therapeutic options, glioblastoma (GBM), the most frequent and aggressive form of all astrocytomas, remains with a median overall survival period of 15 months. A direct correlation between GBM hypoxia and higher aggressiveness, poor prognosis and greater resistance to different treatments has been established. However, because of intratumoral and interindividual heterogeneity, it has not been possible to assess accurately the hypoxia degree from physiopathologica [...]

by Francisco V. Muñoz  and Linda Larkey

Received: 20 May 2020;  Published: 27 July 2020;  doi: 10.21926/obm.icm.2003035

Breast cancer survivors (BCSs) report decrements in cognitive functioning. A Meditative Movement (MM) program (Qigong/Tai Chi Easy) combines meditation and exercise, practices known to improve cognitive function. Method: Using a single group, pre- to post-intervention assessment design, a pilot study was conducted in BCSs to test the effects of an 8-week MM intervention on cognitive functioning, sleep and mood and to explore changes on selected gene expression factors, BDNF, NF-kB1, and TP53, expected to improve wi [...]

by Steven Hespeler  and Donovan Fuqua

Received: 31 July 2020;  Published: 12 January 2021;  doi: 10.21926/jept.2101003

This investigation presents a data-driven Long-short Term Memory battery model for predicting State of Charge for lithium-ion batteries LiFePO4 for next-generation vehicle operations. Our modified algorithm builds and updates a model using multivariate inputs that include physical properties, voltage, current, and ambient temperature during operations. The primary research goal is to improve prediction performance on future values from multiple training examples using an online learning scheme. Initial results demo [...]