Generation of Unexpected Allele-Specific Anti-HLA Antibodies after the Transplantation of a Fully-Matched Kidney Allograft and the Diagnostic Approaches Required for Excluding Harmful Effects after Subsequent Renal Regrafts
Abstract
1883 11319
Generation of Unexpected Allele-Specific Anti-HLA Antibodies after the Transplantation of a Fully-Matched Kidney Allograft and the Diagnostic Approaches Required for Excluding Harmful Effects after Subsequent Renal RegraftsAbstract
The specification of anti-human leukocyte antigen (HLA) antibodies is an important task for patients awaiting kidney allografts. Especially the patients immunized in previous transplantations, transfusions, or pregnancies must be carefully observed, since grafting patients with HLA antigens/phenotypes recognized by their pre-formed antibodies are the main cause of harmful hyperacute and acute rejection. The complement-dependent lymphocytotoxicity-based de facto (physical) crossmatching (CDC-CM) has thus been implem [...] 1883 11319 |
Energy Storage and Installed Wind Capacity Requirements for the Substitution of Fossil Fuels in the Electricity Generation SectorAbstract
The impending adverse effects of Global Climate Change encourages the substitution of fossil fuels with non-carbon sources for electricity generation. However, while fossil fuel power plants may generate electric power at demand, the most abundant renewable energy sources-wind and solar-are intermittent or periodically variable. This necessitates the development of adequate energy storage at the utility/grid level. Using actual data for the hourly energy demand in the ERCOT electricity grid, this study examines the [...] 1621 11318 |
Auriculotherapy for Intractable Hiccups-A Case Reportby
Abstract
A 16 year old girl was evaluated for intractable hiccups for 6 six months, with a prior negative clinical and laboratory evaluation, and without any improvement with a variety of folk and medicinal therapies. A single treatment session of auriculotherapy produced a full clinical remission. 1990 11312 |
Estimating Met-Ocean Parameters during a Tropical Cyclone for Marine Science and Engineeringby
Abstract
During a tropical cyclone (TC) worldwide, the Regional and Mesoscale Meteorological Branch (RAMMB) of NOAA/NESDIS (http://rammb.cira.colostate.edu/) issues real-time TC surface wind analyses. The purpose of this article is to provide value-added estimations of several meteorological and oceanographic (met-ocean) parameters including overwater friction velocity and turbulence intensity, variation of the wind speed with height, significant wave height, peak or dominant wave period, wind-driven currents and wind-stres [...] 2070 11311 |
Enhanced Photocatalytic Degradation of p-Nitrophenol and Phenol Red Through Synergistic Effects of a CeO2-TiO2 NanocompositeAbstract
Organic compounds are one of the most severe pollutants occurring in the environment. Hence, it is important to remove these compounds from the environment through remediation processes such as photocatalysis. The present study investigated the photocatalytic degradation of p-nitrophenol (NP) and phenol red (PR) using a cerium oxide-titanium oxide nanocomposite (CeO2-TiO2nc) under UV light. CeO2-TiO2nc was synthesized using the co-precipitation method. An X-ray diffraction (XRD) analysis confirmed the phase purity [...] 2388 11308 |
Malignant Catatonia Requiring High Dose Bromocriptine: Case ReportAbstract
Catatonia can occur in patients diagnosed with schizophrenia and bipolar disorder and malignant catatonia is life threatening. Anti-psychotic medications should be discontinued during acute phase of catatonia. Anti-psychotic discontinuation in catatonia is a challenge in patients maintained on long-acting injectable antipsychotics because of the extended release. Case report: We present a case of malignant catatonia developed in a patient with history of schizophrenia and developmental delay. Symptoms lasted severa [...] 1448 11306 |
Development of a Novel Pipette Tip-Aided Cell Cloning Method for The Effective Isolation of Genome-Edited Porcine CellAbstract
Direct colony cloning of adherent mammalian cells using rings or dilution cloning has been used frequently for obtaining stable transfectants after gene delivery. As an alternative to these methods, successful isolation of the cells in a single colony is possible by placing a trypsin-immersed small paper disk onto the colony and subsequently picking up the paper with the assumption that it carries the trypsinized cells. However, the cloning success using this technique largely relies on the cell type used. In the p [...] 1995 11300 |
Harvesting the Potential of CO2 before it is Injected into Geological Reservoirsby
Abstract
To store CO2 in geological reservoirs, expansion valves have been used to intentionally release supercritical CO2 from high-pressure containers at a source point to lower-pressure pipelines and transport to a selected injection site. Using expansion valves, however, has some shortcomings: (i) the fluid potential, in the form of kinetic energy and pressure which can produce mechanical work or electricity, is wasted, and (ii) due to the Joule-Thomson cooling effect, the reduction in the temperature of the released CO [...] 3238 11300 |
Where’s Waldo? Extrahepatic Site Options for Islet Transplantationby
Abstract
The current predominant location for allo- and auto-transplantation of islets is the liver. Despite the historical success of this site, recent studies have revealed multiple disadvantages. Portal hypertension, portal vein thrombosis, bleeding, low oxygen tension, instant blood mediated inflammatory reaction, inadequate alpha cell function, and delays in neovascularization are factors that continue to drive researchers to explore alternative sites for islet transplantation. Factors of an optimal site include: capac [...] 1626 11300 |
A Case Series of Temozolomide in the Management of Refractory ProlactinomasAbstract
Objective: To report three cases of refractory prolactinomas treated with Temozolomide (TMZ). Background: Prolactinomas account for 40% of pituitary adenomas. Dopamine agonists (DA) are the first line of treatment followed by surgical resection and radiation. TMZ is an oral chemotherapeutic agent used in gliomas, which has been given to patients with prolactinomas refractory to conventional treatments. Methods: Retrospective chart review was conducted for refractory prolactinoma patients treated between 2008 and 20 [...] 1975 11299 |
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